A lysolipid derivative of glucosylcerebroside; product contains 1-β-D-glucosylsphingadienine isolated from plants

1-β-D-Glucosylsphingadienine (d18:2 (4E,8E)) – 1 mg

Brand:
Cayman
CAS:
114200-59-8
Storage:
-20
UN-No:
Non-Hazardous - /

1-β-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides (Item Nos. 23206 | 23207).{41130} They are formed when sphingosines undergo glucosidation by UDP-glucose.{41131} Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of 10 and 50 μM, respectively. They also decrease the activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner. Glucosylsphingosine levels are elevated in patients with Gaucher’s disease, both in the spleen (in types 1, 2, and 3) and brain (type 2 and 3); thus, glucosylsphingosine has been used as a key biomarker of the disease.{41130,41132} This product contains 1-β-D-glucosylsphingadienine isolated from plants. [Matreya, LLC. Catalog No. 1310]  

 

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SKU: 23213 - 1 mg Category:

Description

A lysolipid derivative of glucosylcerebroside; product contains 1-β-D-glucosylsphingadienine isolated from plants

Formal name: 2S-amino-3R-hydroxy-4E,8E-octadecadienyl, β-D-glucopyranoside

Synonyms:  1-β-D-Glucosylsphingadienine (plant)|Glucosylsphingadienine (d18:2 (4E,8E))|Glucosylsphingosine (plant)

Molecular weight: 459.6

CAS: 114200-59-8

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Lipid Biochemistry|Sphingolipids||Research Area|Neuroscience

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