Δ14-Triamcinolone acetonide – 10 mg

Brand:
Cayman
CAS:
1260149-96-9
Storage:
-20
UN-No:
Non-Hazardous - /

Δ14-Triamcinolone acetonide is a potential impurity found in commercial preparations of triamcinolone acetonide.{35063} Triamcinolone acetonide is a synthetic corticosteroid.{43074} It decreases cytokine levels, the firing rate of sensory neurons, and mechanical hypersensitivity in a rat spinal nerve ligation model when used at a dose of 1.5 mg/kg prior to and following surgery for three days. Triamcinolone acetonide also decreases outflow facility in a mouse model of steroid-induced glaucoma when 20 µl of a 40 mg/ml suspension is administered subconjunctivally.{43075} Formulations containing triamcinolone acetonide are used in the treatment of diabetic macular edema.  

 

Available on backorder

SKU: 9000087 - 10 mg Category:

Description

A potential impurity found in commercial triamcinolone acetonide preparations ,


Formal name: (6aS,6bR,7S,8aS,8bS,11aR,12bS)-6b-fluoro-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12b-decahydro-4H-naphtho[2’,1’:4,5]indeno[1,2-d][1,3]dioxol-4-one

Synonyms:  14,15-dehydro Triamcinolone acetonide|Triamcinolone acetonide Impurity B

Molecular weight: 432.5

CAS: 1260149-96-9

Purity: ≥96%

Formulation: A crystalline solid