A decomposition product of PGD2 in aqueous media in the presence of albumin; exhibits antitumor and antiviral activity

Δ12-Prostaglandin J2 – 500 µg

Brand:
Cayman
CAS:
87893-54-7
Storage:
-80
UN-No:
De Minimis - 1231 / 3

Δ12-PGJ2 is a decomposition product of PGD2 in aqueous media in the presence of albumin.{1742} It has antitumor and antiviral activity, inhibiting growth of cultured L1210 cells at with an IC50 value of 0.7 µg/ml.{334} Δ12-PGJ2 is present in normal human urine with a 24 hour excretion rate of 50-150 ng.{1393} It is also a moderately potent PPARγ ligand.{1424}  

 

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Description

A decomposition product of PGD2 in aqueous media in the presence of albumin; exhibits antitumor and antiviral activity, inhibiting growth of cultured L1210 cells (IC50 = 0.7 µg/ml)

Formal name: 11-oxo-15S-hydroxy-prosta-5Z,9,12E-trien-1-oic acid

Synonyms:  Δ12-PGJ2

Molecular weight: 334.5

CAS: 87893-54-7

Purity: ≥95%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Lipids|Prostaglandins||Product Type|Biochemicals|Receptor Pharmacology||Research Area|Cancer||Research Area|Infectious Disease|Viral Diseases||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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