Immunogen: Human β2-microglobulin protein • Host: Rabbit • Species reactivity: (+) Human and mouse • Applications: ELISA

β2-Microglobulin Polyclonal Antibody – 500 µg

Brand:
Cayman
Storage:

β2-Microglobulin is a 99-amino acid protein and the light chain component of major histocompatibility complex (MHC) class I molecules.{45065} It is non-covalently associated with the MHC class I α chain and comprises a protein-building subunit of the MHC class I molecule to facilitate complex transport to the cell surface and antigen presentation to cytotoxic T cells. β2-Microglobulin is found in cells, as well as in extracellular fluids, including urine and serum, and MHC class I-associated β2-microglobulin exhibits dissociation and equilibrium exchange with circulating soluble β2-microglobulin. Serum levels of β2-microglobulin are increased in patients with renal failure, systemic amyloidosis, various autoimmune diseases, including multiple sclerosis, chronic infections, and a variety of cancers.{45065,45066,45067,45064} It mediates signaling pathways that promote cellular growth, angiogenesis, epithelial-mesenchymal transition (EMT), and bone metastasis and is used as a predictive biomarker of survival in multiple myeloma and colorectal cancers.{45065} Cayman’s β2-Microglobulin Polyclonal Antibody can be used for Western blot and ELISA applications. This antibody recognizes β2-Microglobulin at ~13.7 kDa from human samples.  

 

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SKU: 26130 - 500 µg Category:

Description

Immunogen: Human β2-microglobulin protein • Host: Rabbit • Species reactivity: (+) Human and mouse • Applications: ELISA, WB

Synonyms: β2-M Polyclonal Antibody

Immunogen: Human β2-microglobulin protein

Formulation: 500 µg of Protein A-purified antibody

Isotype:

Applications: ELISA and WB

Origin:

Stability: 365 days

Application|ELISA||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cancer|Cell Migration & Metastasis||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Autoimmunity||Research Area|Neuroscience

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