The C-5 glycoside isomer of uridine; formed when uridine in RNA undergoes site-specific isomerization by a pseudouridine synthase enzyme; found in tRNAs from bacteria

β-Pseudouridine – 25 mg

Brand:
Cayman
CAS:
1445-07-4
Storage:
-20
UN-No:
Non-Hazardous - /

β-Pseudouridine is the C-5 glycoside isomer of the nucleoside uridine (Item No. 20300).{37180} It is formed when uridine in RNA undergoes site-specific isomerization by a pseudouridine synthase enzyme. β-pseudouridine is found in tRNAs from bacteria, archaea, and eukaryotes.{37181} In vitro, it reduces the number of X-ray-induced chromosomal aberrations in human lymphocytes isolated from whole blood in a dose-dependent manner.{37182}  

 

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Description

The C-5 glycoside isomer of uridine; formed when uridine in RNA undergoes site-specific isomerization by a pseudouridine synthase enzyme; found in tRNAs from bacteria, archaea, and eukaryotes; reduces the number of X-ray-induced chromosomal aberrations in human lymphocytes isolated from whole blood in a dose-dependent manner

Formal name: 5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione

Synonyms:  5-Ribosyluracil|NSC 162405

Molecular weight: 244.2

CAS: 1445-07-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis

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