A murine-specific primary bile acid; dietary administration reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet; dietary administration dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones

β-Muricholic Acid – 5 mg

Brand:
Cayman
CAS:
2393-59-1
Storage:
-20
UN-No:
Non-Hazardous - /

β-Muricholic acid (β-MCA) is a murine-specific primary bile acid.{30824,45190} Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet.{33864} Dietary administration of β-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.{33865}  

 

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Description

A murine-specific primary bile acid; dietary administration reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet; dietary administration dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones

Formal name: (5β)-3α,6β,7β-trihydroxy-cholan-24-oic acid

Synonyms:  5β-Cholanic Acid-3α,6β,7β-triol|β-MCA

Molecular weight: 408.6

CAS: 2393-59-1

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Endocrinology & Metabolism|Bile Acids & Microbiome||Research Area|Lipid Biochemistry|Sterol Lipids

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