Description
Antigen: phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser33,37 of human β-catenin · Host: rabbit · Cross-reactivity: (+) human β-catenin · Application: WB • β-Catenin is a central component of the cadherin cell adhesion complex and plays an essential role in neural development in the Wingless/Wnt signaling pathway. It is thought to be regulated by the sequential phosphorylation of Ser29, Ser33, Ser37, and Thr41 by GSK3β. This hyperphosphorylation promotes the ubiquitylation and targeted destruction of β-catenin.
Synonyms: Anti-Phospho-Ser33,37 β-Catenin
Immunogen: phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser33,37 of human .beta.-catenin
Formulation: Affinity-purified IgG
Isotype:
Applications: WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cancer|Cell Signaling|Wnt Signaling||Research Area|Cell Biology|Cell Signaling|Wnt Signaling||Research Area|Cell Biology|ECM & Adhesion Molecules
