A non-reducing inhibitor of 5-LO that shows selectivity for 5-LO over 12-LO or COX; inhibits topoisomerase II activity and arrests cell cycling or induces apoptosis in cancer cells

β-acetyl-Boswellic Acid – 1 mg

Brand:
Cayman
CAS:
5968-70-7
Storage:
-20
UN-No:
Non-Hazardous - /

Boswellic acids are pentacyclic triterpenes first isolated from the resin of Boswellia plants. They have anti-inflammatory and anti-arthritic actions in mice.{30046,30045} β-acetyl-Boswellic acid is a non-reducing inhibitor of 5-lipoxygenase (5-LO) that shows selectivity for 5-LO over 12-LO or COX.{6066,30044} When studied as a 1:1 mixture with α-acetyl-boswellic acid, it inhibits topoisomerase II activity and arrests cell cycling or induces apoptosis in cancer cells.{30048,30047}  

 

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SKU: 11674 - 1 mg Category:

Description

A non-reducing inhibitor of 5-LO that shows selectivity for 5-LO over 12-LO or COX; inhibits topoisomerase II activity and arrests cell cycling or induces apoptosis in cancer cells

Formal name: (3α,4β)-3-(acetyloxy)-urs-12-en-23-oic acid

Synonyms:  3-O-acetyl-β-Boswellic acid|ABA|β-Boswellic acid acetate

Molecular weight: 498.7

CAS: 5968-70-7

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Terpenes||Product Type|Biochemicals|Small Molecule Inhibitors|Lipoxygenases||Product Type|Biochemicals|Small Molecule Inhibitors|Topoisomerases||Research Area|Cancer|Cell Cycle||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|DNA Damage and Repair|Topoisomerase||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Leukotrienes||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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