A major hepatic metabolite of zearalenone that is a less potent agonist of estrogen receptors than the parent compound; has pronounced effects on uterotropic activity

α-Zearalenol – 5 mg

Brand:
Cayman
CAS:
36455-72-8
Storage:
-20
UN-No:
Non-Hazardous - /

α-Zearalenol is a major hepatic metabolite of zearalenone (Item No. 11353), a mycotoxin produced by fungi in food and animal feeds.{20562,27394} It is a less potent agonist of estrogen receptors than the parent compound.{27392} However, α-zearalenol has pronounced effects on uterotropic activity, sperm motility, and preimplantation embryonic development.{27393,27396,27395}  

 

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Description

A major hepatic metabolite of zearalenone that is a less potent agonist of estrogen receptors than the parent compound; has pronounced effects on uterotropic activity, sperm motility, and preimplantation embryonic development

Formal name: (3S,7R,11E)-3,4,5,6,7,8,9,10-octahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one

Synonyms: 

Molecular weight: 320.4

CAS: 36455-72-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Product Type|Biochemicals|Toxins|Mycotoxins||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Toxicology|Drug Metabolism|Drug Metabolites||Research Area|Toxicology|Environmental|Endocrine Disruption

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