A metabolite of the CYP2C19 substrate mephenytoin that has been used for developing UPLC- MS/MS assays for evaluating CYP probe drugs and their relevant metabolites in human urine or plasma samples

(±)4-Hydroxymephenytoin – 5 mg

Brand:
Cayman
CAS:
61837-65-8
Storage:
-20
UN-No:
Non-Hazardous - /

(±)4-Hydroxymephenytoin is a metabolite of (S)-mephenytoin (Item No. 11913), a substrate of the cytochrome P450 (CYP) isoform CYP2C19 with anticonvulsant activities.{23859,23860} It has been used for developing ultra-performance LC tandem mass spectrometry assays for evaluating CYP probe drugs and their relevant metabolites in human urine or plasma samples.{26241}  

 

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Description

A metabolite of the CYP2C19 substrate mephenytoin that has been used for developing UPLC- MS/MS assays for evaluating CYP probe drugs and their relevant metabolites in human urine or plasma samples

Formal name: 5-ethyl-5-(4-hydroxyphenyl)-3-methyl-2,4-imidazolidinedione

Synonyms: 

Molecular weight: 234.3

CAS: 61837-65-8

Purity: ≥98%

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Neuroscience|Seizure Disorders||Research Area|Toxicology|Drug Metabolism|Cytochrome P450||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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