(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane – 50 mg

Brand:
Cayman
CAS:
257641-01-3
Storage:
-20
UN-No:
Non-Hazardous - /

(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (BMC) is a cyclohexane with two mercaptoacetamido groups. It is used, both in vitro and in vivo, to promote the correct folding of proteins that require disulfide bonds for functionality.{28312,28313} For in vitro applications, BMC may be used to facilitate protein refolding of solubilized proteins from inclusion bodies.{28312,28313} Reducing agents, like dithiothreitol, may interfere with refolding. BMC may also be added to the growth medium of cells, including yeast cells, to enhance the folding of proteins with disulfide bonds in vivo.{28313}  

 

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Description

A dithiol used, both in vitro and in vivo, to promote the correct folding of proteins that require disulfide bonds for functionality


Formal name: rel-N,N’-(1R,2R)-1,2-cyclohexanediylbis[2-mercapto-acetamide

Synonyms:  BMC|Vectrase P

Molecular weight: 262.4

CAS: 257641-01-3

Purity: ≥98%

Formulation: A crystalline solid


Application|Sample Preparation||Product Type|Biochemicals||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking|ER Protein Folding