(±)-O-Desmethyl Venlafaxine – 5 mg

Brand:
Cayman
CAS:
93413-62-8
Storage:
-20
UN-No:
Non-Hazardous - /

(±)-O-Desmethyl venlafaxine is the active metabolite of venlafaxine (Item No. 11567), an inhibitor of the reuptake of both serotonin and norepinephrine.{32154,22995,22994} Venlafaxine is metabolized by cytochrome P450 2D6, yielding O-desmethyl venlafaxine, which is pharmacologically similar to the parent drug.{32155,32156} (±)-O-Desmethyl venlafaxine inhibits the human serotonin and norepinephrine transporters with IC50 values of 47.3 and 531.3 nM, respectively.{32153}  

 

Available on backorder

SKU: 9001881 - 5 mg Category:

Description

A CYP2D6 metabolite of venlafaxine that inhibits the human serotonin and norepinephrine transporters (IC50s = 47.3 and 531.3 nM, respectively)


Formal name: 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol

Synonyms:  Desvenlafaxine|DVS 233|MDD-XR

Molecular weight: 263.4

CAS: 93413-62-8

Purity: ≥98%

Formulation: A crystalline solid