(±)-Nicotine – 500 mg

Brand:
Cayman
CAS:
22083-74-5
Storage:
-20
UN-No:
De Minimis - 1654 / 6.1

(±)-Nicotine is the racemic mixture of the dominant alkaloid found in tobacco plants. It acts as an agonist at neuronal nicotinic acetylcholine receptors (nAChRs; Kis = 481 and 11.1 nM for α3β4 and α4β2 subtypes, respectively) and possesses addictive and teratogenic properties.{18814} (−)-(S)-Nicotine is significantly more active at binding nAChRs compared to the (+)-(R) antipode, thus nicotine is typically synthesized as (−)-(S)-nicotine with only 0.2-1% of the (+)-(R) isomer present.{26727}  

 

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Description

The dominant alkaloid found in tobacco plants that acts as an agonist at neuronal nicotinic acetylcholine receptors (nAChRs; Kis = 481 and 11.1 nM for α3β4 and α4β2 subtypes, respectively)


Formal name: 3-(1-methyl-2-pyrrolidinyl)-pyridine

Synonyms:  DL-Nicotine

Molecular weight: 162.2

CAS: 22083-74-5

Purity: ≥98%

Formulation: A neat oil


Product Type|Biochemicals|Ion Channel Modulation||Research Area|Neuroscience