A mixture of trans (3R/7R and 3S/7S) isomers; induces the synthesis of proteinase inhibitors in plant leaves; in cancer cells

(±)-Jasmonic Acid methyl ester – 25 g

Brand:
Cayman
CAS:
39924-52-2
Storage:
-20
UN-No:
Non-Hazardous - /

The jasmonates are a group of plant stress hormones that naturally occur in plants following exposure to certain types of stresses, including pathogen and herbivore attacks. (±)-Jasmonic acid methyl ester is a mixture of trans (3R/7R and 3S/7S) isomers. (±)-Jasmonic acid methyl ester induces the synthesis of proteinase inhibitors in plant leaves.{16943} In cancer cells, it suppresses proliferation and induces apoptosis.{16945} More specifically, methyl jasmonate inhibits hexokinase that is bound to mitochondria.{16944} As hexokinase is overexpressed in cancer cells and contributes to cancer cell growth and survival, methyl jasmonate’s disruption of mitochondrial hexokinase activity selectively targets, and kills, cancer cells. (±)-Jasmonic acid methyl ester derivatives also have potential as anti-inflammatory agents.{16946}  

 

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SKU: 9000059 - 25 g Category:

Description

A mixture of trans (3R/7R and 3S/7S) isomers; induces the synthesis of proteinase inhibitors in plant leaves; in cancer cells, suppresses proliferation and induces apoptosis; inhibits hexokinase that is bound to mitochondria; methyl jasmonate derivatives also have potential as anti-inflammatory agents.

Formal name: 3-oxo-2-(2-penten-1-yl)-cyclopentaneacetic acid, methyl ester

Synonyms:  (±)-Methyl Jasmonate

Molecular weight: 224.3

CAS: 39924-52-2

Purity: ≥95% (mixture of isomers)

Formulation: A neat oil

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