A goitrogen; dietary administration increases thyroid weight and decreases thyroid radioactive iodine uptake in rats fed a low-iodine diet at 0.06-0.18% w/w; increases thyroid weight in chicks; inhibits norepinephrine formation by bovine dopamine-β-hydroxylase in vitro at 0.2 mM

(±)-Goitrin – 25 mg

Brand:
Cayman
CAS:
13190-34-6
Storage:
-20
UN-No:
Non-Hazardous - /

(±)-Goitrin is a goitrogen and antithyroid compound that has been found in plants of the Brassica family.{46142,46143} Dietary administration of (±)-goitrin (0.06-0.18% w/w) increases thyroid weight and decreases thyroid radioactive iodine uptake in rats fed a low-iodine diet.{46142} It also increases thyroid weight in chicks in a dose-dependent manner.{46143} (±)-Goitrin inhibits norepinephrine formation by bovine dopamine-β-hydroxylase in vitro when used at a concentration of 0.2 mM.{46144}  

 

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Description

A goitrogen; dietary administration increases thyroid weight and decreases thyroid radioactive iodine uptake in rats fed a low-iodine diet at 0.06-0.18% w/w; increases thyroid weight in chicks; inhibits norepinephrine formation by bovine dopamine-β-hydroxylase in vitro at 0.2 mM,

Formal name: 5-ethenyl-2-oxazolidinethione

Synonyms:  DL-Goitrin

Molecular weight: 129.2

CAS: 13190-34-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products||Research Area|Toxicology

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