(±)-C75 – 5 mg

Brand:
Cayman
CAS:
191282-48-1
Storage:
-20
UN-No:
Non-Hazardous - /

Inhibition of fatty acid synthase (FASN) by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines.{11992} (±)-C75 is a stable inhibitor of FASN that leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice.{7659} (±)-C75 is also cytotoxic to many human cancer cell lines, an effect believed to be mediated by the accumulation of malonyl-coenzyme A in cells with an upregulated FASN pathway.{11993}  

 

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SKU: 10005270 - 5 mg Category:

Description

A stable inhibitor of FASN that leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice


Formal name: tetrahydro-4-methylene-2R-octyl-5-oxo-3S-furancarboxylic acid

Synonyms: 

Molecular weight: 254.3

CAS: 191282-48-1

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cancer|Metabolism||Research Area|Endocrinology & Metabolism|Cofactors & Vitamins||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity