(±)-Atenolol – 5 g

Brand:
Cayman
CAS:
29122-68-7
Storage:
-20
UN-No:
Non-Hazardous - /

(±)-Atenolol is an antagonist of the β1-adrenergic receptor (β1-AR; Ki = 1.14 µM).{28226} It is selective for β1-ARs over β2-ARs (Ki = 48.7 µM). (±)-Atenolol (200 mg/kg per day) delays the onset of hypertension in spontaneously hypertensive rats.{49503} Formulations containing atenolol have been used in the treatment of high blood pressure.  

 

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Description

A β1-AR antagonist (Ki = 1.14 µM); selective for β1-ARs over β2-ARs (Ki = 48.7 µM); delays the onset of hypertension in spontaneously hypertensive rats at 200 mg/kg


Formal name: 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-benzeneacetamide

Synonyms:  ​(R,S)-Atenolol|Duraatenol|ICI 66082

Molecular weight: 266.3

CAS: 29122-68-7

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Heart|Arrhythmia