A non-selective dopamine receptor agonist (pKis = 6.43

(−)-Apomorphine (hydrochloride) – 100 mg

Brand:
Cayman
CAS:
314-19-2
Storage:
-20
UN-No:
Non-Hazardous - /

(−)-Apomorphine is a non-selective dopamine receptor agonist that exhibits pKi values of 6.43, 7.08, 7.59, 8.36, and 7.83 for human recombinant D1, D2L, D3, D4, and D5 receptors, respectively.{21785,17063} It produces biphasic effects on locomotor activity and displays anti-parkinsonian and neuroprotective actions.{21785,21786,23301}  

 

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Description

A non-selective dopamine receptor agonist (pKis = 6.43, 7.08, 7.59, 8.36, and 7.83 for human recombinant D1, D2L, D3, D4, and D5 receptors, respectively); produces biphasic effects on locomotor activity and displays anti-parkinsonian and neuroprotective actions

Formal name: 5,6,6aR,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol, monohydrochloride

Synonyms:  NSC 11442|Uprima

Molecular weight: 303.8

CAS: 314-19-2

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Neurodegenerative Disorders|Parkinson’s Disease

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