A quantitative analytical standard guaranteed to meet MaxSpec® identity

(±)18-HEPE MaxSpec® Standard – 10 µg

Brand:
Cayman
CAS:
141110-17-0
Storage:
-20
UN-No:
De Minimis - 1170 / 3

(±)18-HEPE is produced by non-enzymatic oxidation of eicosapentaenoic acid (EPA; Item Nos. 90110 | 90110.1 | 21908).{53027} 18-HEPE levels are increased in the plasma and heart, as well as in the supernatant of cultured peritoneal macrophages isolated from fat-1 transgenic mice that are capable of endogenously producing ω-3 fatty acids from ω-6 fatty acids.{53024,53025,53026} It reduces increases in cardiac fibrosis and the expression of Nppa, Col1a1, Tgfb1, Cx3cl1, and Adgre1 induced by transverse aortic constriction in a mouse model of cardiac hypertrophy when administered at doses of 1 and 5 µg.{53025} (±)18-HEPE MaxSpec® standard is a quantitative grade standard of (±)18-HEPE (Item No. 32840) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This (±)18-HEPE MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.  

 

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SKU: 23567 - 10 µg Category:

Description

A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications

Formal name: (±)-18-hydroxy-5Z,8Z,11Z,14Z,16E-eicosapentaenoic acid

Synonyms:  (±)18-Hydroxyeicosapentaenoic Acid|(±)18-hydroxy-EPA

Molecular weight: 318.5

CAS: 141110-17-0

Purity: ≥95%

Formulation: A solution in ethanol at 10 µg/ml

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards|MaxSpec®||Product Type|Biochemicals|Lipids|Hydroxy/Hydroperoxy/ Epoxy/Oxo Eicosanoids||Research Area|Cardiovascular System|Heart|Myocardial Hypertrophy||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Reactive O2/N2 Pathways||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation

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