A quantitative analytical standard guaranteed to meet MaxSpec® identity

(±)17-HDHA MaxSpec® Standard – 100 µg

Brand:
Cayman
CAS:
90780-52-2
Storage:
-20
UN-No:
De Minimis - 1170 / 3

(±)17-HDHA is an autoxidation product of docosahexaenoic acid (DHA; Item No. 90310) in vitro.{7479,7491} It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.{7480,7490,7492} 17(S)-HDHA (Item No. 10009799) could be produced by enzymatic oxidation of DHA using soybean lipoxygenase (LO) and is the putative product of mammalian 15-LOs.{7492} 17(S)-HDHA was shown to be an inhibitor of U-46619 (Item No. 16450) -induced rabbit and rat aortic smooth muscle contraction with IC50 values of 4.9 and 7.2 µM, respectively.{7481} (±)17-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid. (±)17-HDHA MaxSpec® standard is a quantitative grade standard of (±)17-HDHA (Item No. 33650) that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This (±)17-HDHA MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.  

 

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SKU: 10007223 - 100 µg Category:

Description

A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications,

Formal name: (±)17-hydroxy-4Z,7Z,10Z,13Z,15Z,19Z-docosahexaenoic acid

Synonyms:  (±)17-HDoHE|17-hydroxy DHA|17-hydroxy Docosahexaenoic Acid

Molecular weight: 344.5

CAS: 90780-52-2

Purity: ≥95%

Formulation: A solution in ethanol at 100 µg/ml

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards|MaxSpec®||Product Type|Biochemicals|Lipids|Docosanoids||Research Area|Lipid Biochemistry|Reactive O2/N2 Pathways||Research Area|Neuroscience|Ophthalmology||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation

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