Cayman
Showing 7201–7350 of 45550 results
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7-Aminoactinomycin D (7-AAD) is a fluorescent DNA dye that is commonly used for the detection or exclusion of non-viable cells in flow cytometric analysis, as it is generally excluded by live cells.{21244,16311} It displays excitation spectra of 488, 546, and 578 nm and an emission spectrum of 650 nm.{41095} As 7-AAD is detected in the far red range of the spectrum, it exhibits minimal spectral overlap with commonly used probes, therefore it can be used in conjunction with probes such as FITC.{21244,41095} 7-AAD has been used to evaluate apoptosis and cell-mediated cytotoxicity and to stain DNA in cells that have been fixed and permeabilized by a variety of methods.{21244,16311,21243}
Brand:CaymanSKU:11397 - 1 mgAvailable on backorder
7-Aminoactinomycin D (7-AAD) is a fluorescent DNA dye that is commonly used for the detection or exclusion of non-viable cells in flow cytometric analysis, as it is generally excluded by live cells.{21244,16311} It displays excitation spectra of 488, 546, and 578 nm and an emission spectrum of 650 nm.{41095} As 7-AAD is detected in the far red range of the spectrum, it exhibits minimal spectral overlap with commonly used probes, therefore it can be used in conjunction with probes such as FITC.{21244,41095} 7-AAD has been used to evaluate apoptosis and cell-mediated cytotoxicity and to stain DNA in cells that have been fixed and permeabilized by a variety of methods.{21244,16311,21243}
Brand:CaymanSKU:11397 - 5 mgAvailable on backorder
7-APB is a derivative of the designer drug 6-APB (Item No. 11079), also known as benzo fury, and is a stimulant and entactogen belonging to the amphetamine and the phenethylamine classes.{22885} It is an analog of MDA (Item No. 11554) where the 3,4-methylenedioxyphenyl ring system has been replaced with a benzofuran ring. This product is intended for forensic purposes.
Brand:CaymanSKU:- 7-APB is a derivative of the designer drug 6-APB (Item No. 11079), also known as benzo fury, and is a stimulant and entactogen belonging to the amphetamine and the phenethylamine classes.{22885} It is an analog of MDA (Item No. 11554) where the 3,4-methylenedioxyphenyl ring system has been replaced with a benzofuran ring. This product is intended for forensic purposes.
Brand:CaymanSKU:- 7-APB is a derivative of the designer drug 6-APB (Item No. 11079), also known as benzo fury, and is a stimulant and entactogen belonging to the amphetamine and the phenethylamine classes.{22885} It is an analog of MDA (Item No. 11554) where the 3,4-methylenedioxyphenyl ring system has been replaced with a benzofuran ring. This product is intended for forensic purposes.
Brand:CaymanSKU:-
7-Azido-4-methylcoumarin (AzMC) is a coumarin fluorescent probe for hydrogen sulfide (H2S).{48665} AzMC selectively fluoresces in the presence of H2S over a panel of reactive nitrogen, oxygen, and sulfur species. AzMC displays excitation/emission maxima of 340/445 nm, respectively.
Brand:CaymanSKU:28307 - 1 mgAvailable on backorder
7-Azido-4-methylcoumarin (AzMC) is a coumarin fluorescent probe for hydrogen sulfide (H2S).{48665} AzMC selectively fluoresces in the presence of H2S over a panel of reactive nitrogen, oxygen, and sulfur species. AzMC displays excitation/emission maxima of 340/445 nm, respectively.
Brand:CaymanSKU:28307 - 5 mgAvailable on backorder
7-Biopterin is a 7-substituted pterin.{54021} It is formed by non-enzymatic rearrangement of 4a-hydroxy-tetrahydropterin in the absence of pterin-4a-carbinolamine dehydratase (PCD) in vitro and levels are elevated in the urine of hyperphenylalaninemia patients carrying heterozygous mutations in the PCBD gene encoding PCD.{54021,54022}
Brand:CaymanSKU:29819 - 1 mgAvailable on backorder
7-Biopterin is a 7-substituted pterin.{54021} It is formed by non-enzymatic rearrangement of 4a-hydroxy-tetrahydropterin in the absence of pterin-4a-carbinolamine dehydratase (PCD) in vitro and levels are elevated in the urine of hyperphenylalaninemia patients carrying heterozygous mutations in the PCBD gene encoding PCD.{54021,54022}
Brand:CaymanSKU:29819 - 10 mgAvailable on backorder
7-Biopterin is a 7-substituted pterin.{54021} It is formed by non-enzymatic rearrangement of 4a-hydroxy-tetrahydropterin in the absence of pterin-4a-carbinolamine dehydratase (PCD) in vitro and levels are elevated in the urine of hyperphenylalaninemia patients carrying heterozygous mutations in the PCBD gene encoding PCD.{54021,54022}
Brand:CaymanSKU:29819 - 5 mgAvailable on backorder
7-Biopterin is a 7-substituted pterin.{54021} It is formed by non-enzymatic rearrangement of 4a-hydroxy-tetrahydropterin in the absence of pterin-4a-carbinolamine dehydratase (PCD) in vitro and levels are elevated in the urine of hyperphenylalaninemia patients carrying heterozygous mutations in the PCBD gene encoding PCD.{54021,54022}
Brand:CaymanSKU:29819 - 500 µgAvailable on backorder
7-Bromoheptanoic acid is a building block.{17893,41832} It has been used in the synthesis of azide-based nicotinamide phosphoribosyltransferase (Nampt) inhibitors with anticancer activity and SAHA (Item No. 10009929) derivatives that inhibit histone deacetylases (HDACs).
Brand:CaymanSKU:30420 - 1 gAvailable on backorder
7-Bromoheptanoic acid is a building block.{17893,41832} It has been used in the synthesis of azide-based nicotinamide phosphoribosyltransferase (Nampt) inhibitors with anticancer activity and SAHA (Item No. 10009929) derivatives that inhibit histone deacetylases (HDACs).
Brand:CaymanSKU:30420 - 10 gAvailable on backorder
7-Bromoheptanoic acid is a building block.{17893,41832} It has been used in the synthesis of azide-based nicotinamide phosphoribosyltransferase (Nampt) inhibitors with anticancer activity and SAHA (Item No. 10009929) derivatives that inhibit histone deacetylases (HDACs).
Brand:CaymanSKU:30420 - 5 gAvailable on backorder
Brand:CaymanSKU:10007081 - 1 gAvailable on backorder
Brand:CaymanSKU:10007081 - 5 gAvailable on backorder
Brand:CaymanSKU:10007081 - 500 mgAvailable on backorder
Brand:CaymanSKU:10007135 - 100 mgAvailable on backorder
Brand:CaymanSKU:10007135 - 250 mgAvailable on backorder
Brand:CaymanSKU:10007135 - 50 mgAvailable on backorder
Brand:CaymanSKU:10007135 - 500 mgAvailable on backorder
Brand:CaymanSKU:10007094 - 1 gAvailable on backorder
Brand:CaymanSKU:10007094 - 100 mgAvailable on backorder
Brand:CaymanSKU:10007094 - 5 gAvailable on backorder
Brand:CaymanSKU:10007094 - 500 mgAvailable on backorder
7-dehydro Cholesterol (7-DHC) is an immediate precursor of cholesterol.{22849} It is reduced to cholesterol by the enzyme 3β-hydroxysterol-Δ7-reductase (DHCR7) in the last step of cholesterol biosynthesis. 7-DHC accumulates in Smith-Lemli-Opitz syndrome (SLOS), a disorder characterized by a mutation in the DHCR7 gene and decreased cholesterol levels in bodily tissues and fluids, as well as microcephaly, intellectual disability, and distinctive dysmorphic features.{22849,27281} It is highly susceptible to free radical oxidation, giving rise to several oxysterols that may be involved in the pathogenesis of SLOS.{22849} 7-DHC levels are increased in brain, liver, and serum in a rat model of SLOS induced by the DHCR7 inhibitor AY 9944 (Item No. 14611).{22849} 7-DHC is a provitamin that is converted to vitamin D3 (Item No. 11792) by ultraviolet-B (UVB) light in a human skin equivalent system and in isolated human skin samples.{23284,23286}
Brand:CaymanSKU:- 7-dehydro Cholesterol (7-DHC) is an immediate precursor of cholesterol.{22849} It is reduced to cholesterol by the enzyme 3β-hydroxysterol-Δ7-reductase (DHCR7) in the last step of cholesterol biosynthesis. 7-DHC accumulates in Smith-Lemli-Opitz syndrome (SLOS), a disorder characterized by a mutation in the DHCR7 gene and decreased cholesterol levels in bodily tissues and fluids, as well as microcephaly, intellectual disability, and distinctive dysmorphic features.{22849,27281} It is highly susceptible to free radical oxidation, giving rise to several oxysterols that may be involved in the pathogenesis of SLOS.{22849} 7-DHC levels are increased in brain, liver, and serum in a rat model of SLOS induced by the DHCR7 inhibitor AY 9944 (Item No. 14611).{22849} 7-DHC is a provitamin that is converted to vitamin D3 (Item No. 11792) by ultraviolet-B (UVB) light in a human skin equivalent system and in isolated human skin samples.{23284,23286}
Brand:CaymanSKU:- 7-dehydro Cholesterol (7-DHC) is an immediate precursor of cholesterol.{22849} It is reduced to cholesterol by the enzyme 3β-hydroxysterol-Δ7-reductase (DHCR7) in the last step of cholesterol biosynthesis. 7-DHC accumulates in Smith-Lemli-Opitz syndrome (SLOS), a disorder characterized by a mutation in the DHCR7 gene and decreased cholesterol levels in bodily tissues and fluids, as well as microcephaly, intellectual disability, and distinctive dysmorphic features.{22849,27281} It is highly susceptible to free radical oxidation, giving rise to several oxysterols that may be involved in the pathogenesis of SLOS.{22849} 7-DHC levels are increased in brain, liver, and serum in a rat model of SLOS induced by the DHCR7 inhibitor AY 9944 (Item No. 14611).{22849} 7-DHC is a provitamin that is converted to vitamin D3 (Item No. 11792) by ultraviolet-B (UVB) light in a human skin equivalent system and in isolated human skin samples.{23284,23286}
Brand:CaymanSKU:- 7-dehydro Cholesterol (7-DHC) is an immediate precursor of cholesterol.{22849} It is reduced to cholesterol by the enzyme 3β-hydroxysterol-Δ7-reductase (DHCR7) in the last step of cholesterol biosynthesis. 7-DHC accumulates in Smith-Lemli-Opitz syndrome (SLOS), a disorder characterized by a mutation in the DHCR7 gene and decreased cholesterol levels in bodily tissues and fluids, as well as microcephaly, intellectual disability, and distinctive dysmorphic features.{22849,27281} It is highly susceptible to free radical oxidation, giving rise to several oxysterols that may be involved in the pathogenesis of SLOS.{22849} 7-DHC levels are increased in brain, liver, and serum in a rat model of SLOS induced by the DHCR7 inhibitor AY 9944 (Item No. 14611).{22849} 7-DHC is a provitamin that is converted to vitamin D3 (Item No. 11792) by ultraviolet-B (UVB) light in a human skin equivalent system and in isolated human skin samples.{23284,23286}
Brand:CaymanSKU:-
7-dehydro Cholesterol-d7 is intended for use as an internal standard for the quantification of 7-dehydro cholesterol (Item No. 14612) by GC- or LC-MS. 7-dehydro Cholesterol (7-DHC) is an immediate precursor of cholesterol.{22849} It is reduced to cholesterol by the enzyme 3β-hydroxysterol-Δ7-reductase (DHCR7) in the last step of cholesterol biosynthesis. It accumulates in Smith-Lemli-Opitz syndrome (SLOS), a disorder characterized by a mutation in the DHCR7 gene and decreased cholesterol levels in bodily tissues and fluids, as well as microcephaly, intellectual disability, and distinctive dysmorphic features.{22849,27281} 7-DHC is highly susceptible to free radical oxidation, giving rise to several oxysterols that may be involved in the pathogenesis of SLOS.{22849} 7-DHC levels are increased in brain, liver, and serum in a rat model of SLOS induced by the DHCR7 inhibitor AY 9944 (Item No. 14611).{22849} 7-DHC is also a provitamin that is converted to vitamin D3 (Item No. 11792) by ultraviolet-B (UVB) light in a human skin equivalent system and in isolated human skin samples.{23284,23286}
Brand:CaymanSKU:25969 - 1 mgAvailable on backorder
7-dehydro Cholesterol-d7 is intended for use as an internal standard for the quantification of 7-dehydro cholesterol (Item No. 14612) by GC- or LC-MS. 7-dehydro Cholesterol (7-DHC) is an immediate precursor of cholesterol.{22849} It is reduced to cholesterol by the enzyme 3β-hydroxysterol-Δ7-reductase (DHCR7) in the last step of cholesterol biosynthesis. It accumulates in Smith-Lemli-Opitz syndrome (SLOS), a disorder characterized by a mutation in the DHCR7 gene and decreased cholesterol levels in bodily tissues and fluids, as well as microcephaly, intellectual disability, and distinctive dysmorphic features.{22849,27281} 7-DHC is highly susceptible to free radical oxidation, giving rise to several oxysterols that may be involved in the pathogenesis of SLOS.{22849} 7-DHC levels are increased in brain, liver, and serum in a rat model of SLOS induced by the DHCR7 inhibitor AY 9944 (Item No. 14611).{22849} 7-DHC is also a provitamin that is converted to vitamin D3 (Item No. 11792) by ultraviolet-B (UVB) light in a human skin equivalent system and in isolated human skin samples.{23284,23286}
Brand:CaymanSKU:25969 - 500 µgAvailable on backorder
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe.{42339} It displays excitation/emission maxima of 387/468 nm, respectively, and fluorescence intensity increases when bound to cysteine residues.{42340}
Brand:CaymanSKU:-Available on backorder
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe.{42339} It displays excitation/emission maxima of 387/468 nm, respectively, and fluorescence intensity increases when bound to cysteine residues.{42340}
Brand:CaymanSKU:-Available on backorder
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe.{42339} It displays excitation/emission maxima of 387/468 nm, respectively, and fluorescence intensity increases when bound to cysteine residues.{42340}
Brand:CaymanSKU:-Available on backorder
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe.{42339} It displays excitation/emission maxima of 387/468 nm, respectively, and fluorescence intensity increases when bound to cysteine residues.{42340}
Brand:CaymanSKU:-Available on backorder
7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1 (Item No. 10878), which contains a 7(R) hydroxyl group. It can be used as an experimental negative control.
Brand:CaymanSKU:- 7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1 (Item No. 10878), which contains a 7(R) hydroxyl group. It can be used as an experimental negative control.
Brand:CaymanSKU:- 7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1 (Item No. 10878), which contains a 7(R) hydroxyl group. It can be used as an experimental negative control.
Brand:CaymanSKU:- 7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1 (Item No. 10878), which contains a 7(R) hydroxyl group. It can be used as an experimental negative control.
Brand:CaymanSKU:-
7-epi Paclitaxel is an active metabolite of paclitaxel (Taxol; Item No. 10461), a widely used chemotherapeutic compound.{32610} It is the major metabolite found in cells, although 6α-hydroxy paclitaxel (6α-hydroxy Taxol; Item No. 10009027) is the major biliary metabolite of paclitaxel in humans.{32610,32609} 7-epi Paclitaxel exhibits properties comparable to paclitaxel on both cells and in vitro microtubule polymerization.{32609}
Brand:CaymanSKU:20741 -Available on backorder
7-epi Paclitaxel is an active metabolite of paclitaxel (Taxol; Item No. 10461), a widely used chemotherapeutic compound.{32610} It is the major metabolite found in cells, although 6α-hydroxy paclitaxel (6α-hydroxy Taxol; Item No. 10009027) is the major biliary metabolite of paclitaxel in humans.{32610,32609} 7-epi Paclitaxel exhibits properties comparable to paclitaxel on both cells and in vitro microtubule polymerization.{32609}
Brand:CaymanSKU:20741 -Available on backorder
7-epi Paclitaxel is an active metabolite of paclitaxel (Taxol; Item No. 10461), a widely used chemotherapeutic compound.{32610} It is the major metabolite found in cells, although 6α-hydroxy paclitaxel (6α-hydroxy Taxol; Item No. 10009027) is the major biliary metabolite of paclitaxel in humans.{32610,32609} 7-epi Paclitaxel exhibits properties comparable to paclitaxel on both cells and in vitro microtubule polymerization.{32609}
Brand:CaymanSKU:20741 -Available on backorder
7-epi Paclitaxel is an active metabolite of paclitaxel (Taxol; Item No. 10461), a widely used chemotherapeutic compound.{32610} It is the major metabolite found in cells, although 6α-hydroxy paclitaxel (6α-hydroxy Taxol; Item No. 10009027) is the major biliary metabolite of paclitaxel in humans.{32610,32609} 7-epi Paclitaxel exhibits properties comparable to paclitaxel on both cells and in vitro microtubule polymerization.{32609}
Brand:CaymanSKU:20741 -Available on backorder
7-ethoxy-4-Methylcoumarin is a fluorophore that has been used to monitor functional activity of cytochrome P450 (CYP)1A1, CYP2B4, and CYP2B6.{31458,31457} It demonstrates excitation/emission maxima of 318 and 377 nm, respectively in methanol and 360 and 449 nm, respectively in dealkylase.
Brand:CaymanSKU:19586 -Available on backorder
7-ethoxy-4-Methylcoumarin is a fluorophore that has been used to monitor functional activity of cytochrome P450 (CYP)1A1, CYP2B4, and CYP2B6.{31458,31457} It demonstrates excitation/emission maxima of 318 and 377 nm, respectively in methanol and 360 and 449 nm, respectively in dealkylase.
Brand:CaymanSKU:19586 -Available on backorder
7-ethoxy-4-Methylcoumarin is a fluorophore that has been used to monitor functional activity of cytochrome P450 (CYP)1A1, CYP2B4, and CYP2B6.{31458,31457} It demonstrates excitation/emission maxima of 318 and 377 nm, respectively in methanol and 360 and 449 nm, respectively in dealkylase.
Brand:CaymanSKU:19586 -Available on backorder
7-Ethoxycoumarin is a substrate for cytochrome P450 (CYP).{57183} It undergoes O-deethylation by various CYP isoforms, including CYP1A1, -1A2, and -2B in mice and CYP2E1 in humans. 7-Ethoxycoumarin has been used in the functional characterization of CYPs in cats, rats, and isolated human cornea.{57184,57185,57186}
Brand:CaymanSKU:31215 - 1 gAvailable on backorder
7-Ethoxycoumarin is a substrate for cytochrome P450 (CYP).{57183} It undergoes O-deethylation by various CYP isoforms, including CYP1A1, -1A2, and -2B in mice and CYP2E1 in humans. 7-Ethoxycoumarin has been used in the functional characterization of CYPs in cats, rats, and isolated human cornea.{57184,57185,57186}
Brand:CaymanSKU:31215 - 100 mgAvailable on backorder
7-Ethoxycoumarin is a substrate for cytochrome P450 (CYP).{57183} It undergoes O-deethylation by various CYP isoforms, including CYP1A1, -1A2, and -2B in mice and CYP2E1 in humans. 7-Ethoxycoumarin has been used in the functional characterization of CYPs in cats, rats, and isolated human cornea.{57184,57185,57186}
Brand:CaymanSKU:31215 - 250 mgAvailable on backorder
7-Ethoxycoumarin is a substrate for cytochrome P450 (CYP).{57183} It undergoes O-deethylation by various CYP isoforms, including CYP1A1, -1A2, and -2B in mice and CYP2E1 in humans. 7-Ethoxycoumarin has been used in the functional characterization of CYPs in cats, rats, and isolated human cornea.{57184,57185,57186}
Brand:CaymanSKU:31215 - 500 mgAvailable on backorder
7-Ethoxyresorufin (7-ER) is a fluorogenic substrate for, and competitive inhibitor of, the cytochrome P450 (CYP) isoform CYP1A1 (IC50 = 0.1 µM).{26089,26092,26091} Upon enzymatic cleavage by CYP1A1, resorufin is released and its fluorescence can be used to quantify CYP1A1 activity. Resorufin displays excitation/emission maxima of 570/580 nm, respectively.{50356} 7-ER has been used in the study of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) metabolism and the mechanisms of vasodilation.{15972,12467} 7-ER is a noncompetitive inhibitor of neuronal nitric oxide synthase (nNOS; Ki = 0.76 µM).{26088,26090}
Brand:CaymanSKU:- 7-Ethoxyresorufin (7-ER) is a fluorogenic substrate for, and competitive inhibitor of, the cytochrome P450 (CYP) isoform CYP1A1 (IC50 = 0.1 µM).{26089,26092,26091} Upon enzymatic cleavage by CYP1A1, resorufin is released and its fluorescence can be used to quantify CYP1A1 activity. Resorufin displays excitation/emission maxima of 570/580 nm, respectively.{50356} 7-ER has been used in the study of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) metabolism and the mechanisms of vasodilation.{15972,12467} 7-ER is a noncompetitive inhibitor of neuronal nitric oxide synthase (nNOS; Ki = 0.76 µM).{26088,26090}
Brand:CaymanSKU:-
7-fluoro Tryptamine is a tryptamine derivative that potentially agonizes 5-HT serotonin receptors. Although the biological effects of this compound have not been reported, certain hallucinogenic typtamines containing a fluorine substitution at the 5-, 6-, or 7-position have been shown to have 5-HT2C receptor selectivity over both the 5HT2A and 5-HT2B subtypes.{29113,25254} This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
7-fluoro Tryptamine is a tryptamine derivative that potentially agonizes 5-HT serotonin receptors. Although the biological effects of this compound have not been reported, certain hallucinogenic typtamines containing a fluorine substitution at the 5-, 6-, or 7-position have been shown to have 5-HT2C receptor selectivity over both the 5HT2A and 5-HT2B subtypes.{29113,25254} This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
7-fluoro Tryptamine is a tryptamine derivative that potentially agonizes 5-HT serotonin receptors. Although the biological effects of this compound have not been reported, certain hallucinogenic typtamines containing a fluorine substitution at the 5-, 6-, or 7-position have been shown to have 5-HT2C receptor selectivity over both the 5HT2A and 5-HT2B subtypes.{29113,25254} This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
7-fluoro Tryptamine is a tryptamine derivative that potentially agonizes 5-HT serotonin receptors. Although the biological effects of this compound have not been reported, certain hallucinogenic typtamines containing a fluorine substitution at the 5-, 6-, or 7-position have been shown to have 5-HT2C receptor selectivity over both the 5HT2A and 5-HT2B subtypes.{29113,25254} This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
7-hydroxy Coumarin glucuronide is a 7-hydroxy coumarin phase II metabolite that can be used as a standard for the analysis of 7-hydroxy coumarin metabolism.
Brand:CaymanSKU:19882 -Available on backorder
7-hydroxy Coumarin glucuronide is a 7-hydroxy coumarin phase II metabolite that can be used as a standard for the analysis of 7-hydroxy coumarin metabolism.
Brand:CaymanSKU:19882 -Available on backorder
7-hydroxy Coumarin glucuronide is a 7-hydroxy coumarin phase II metabolite that can be used as a standard for the analysis of 7-hydroxy coumarin metabolism.
Brand:CaymanSKU:19882 -Available on backorder
7-hydroxy Coumarin glucuronide is a 7-hydroxy coumarin phase II metabolite that can be used as a standard for the analysis of 7-hydroxy coumarin metabolism.
Brand:CaymanSKU:19882 -Available on backorder
7-hydroxy Coumarin sulfate is a phase II metabolite of coumarin that can be used as an internal standard for the analysis of 7-hydroxy coumarin metabolism using GC- or LC-MS.{39157,39159,39158}
Brand:CaymanSKU:20892 -Out of stock
7-hydroxy Coumarin sulfate is a phase II metabolite of coumarin that can be used as an internal standard for the analysis of 7-hydroxy coumarin metabolism using GC- or LC-MS.{39157,39159,39158}
Brand:CaymanSKU:20892 -Out of stock
7-hydroxy Coumarin sulfate is a phase II metabolite of coumarin that can be used as an internal standard for the analysis of 7-hydroxy coumarin metabolism using GC- or LC-MS.{39157,39159,39158}
Brand:CaymanSKU:20892 -Out of stock
7-hydroxy DPAT is a dopamine D3 receptor agonist.{52357} It selectively binds to the dopamine D3 over the D2, D1, and D4 receptors (Kis = 0.78, 61, 650, and 5,300 nM, respectively, in radioligand binding assays). 7-hydroxy DPAT increases calcium mobilization in HEK293 cells expressing the D3 receptor with an EC50 value of 13.5 nM in a FLIPR assay.{52358} It decreases the release of striatal dopamine and its metabolite 3,4-dihydroxyphenylacetic acid (DOPAC; Item No. 24912) in rats when administered intraperitoneally at a dose of 0.25 mg/kg.{52359} 7-hydroxy DPAT (2 µg/µl for eight weeks, i.c.v.) reduces the loss of ipsilateral substantia nigra pars compacta (SNC) dopaminergic neurons in a rat model of Parkinson’s disease induced by 6-OHDA (Item No. 25330).{52360} It also decreases amphetamine-induced ipsilateral rotations and increases the number of steps reached with the contralateral paw in the staircase test in the same model.
Brand:CaymanSKU:29516 - 10 mgAvailable on backorder
7-hydroxy DPAT is a dopamine D3 receptor agonist.{52357} It selectively binds to the dopamine D3 over the D2, D1, and D4 receptors (Kis = 0.78, 61, 650, and 5,300 nM, respectively, in radioligand binding assays). 7-hydroxy DPAT increases calcium mobilization in HEK293 cells expressing the D3 receptor with an EC50 value of 13.5 nM in a FLIPR assay.{52358} It decreases the release of striatal dopamine and its metabolite 3,4-dihydroxyphenylacetic acid (DOPAC; Item No. 24912) in rats when administered intraperitoneally at a dose of 0.25 mg/kg.{52359} 7-hydroxy DPAT (2 µg/µl for eight weeks, i.c.v.) reduces the loss of ipsilateral substantia nigra pars compacta (SNC) dopaminergic neurons in a rat model of Parkinson’s disease induced by 6-OHDA (Item No. 25330).{52360} It also decreases amphetamine-induced ipsilateral rotations and increases the number of steps reached with the contralateral paw in the staircase test in the same model.
Brand:CaymanSKU:29516 - 25 mgAvailable on backorder
7-hydroxy DPAT is a dopamine D3 receptor agonist.{52357} It selectively binds to the dopamine D3 over the D2, D1, and D4 receptors (Kis = 0.78, 61, 650, and 5,300 nM, respectively, in radioligand binding assays). 7-hydroxy DPAT increases calcium mobilization in HEK293 cells expressing the D3 receptor with an EC50 value of 13.5 nM in a FLIPR assay.{52358} It decreases the release of striatal dopamine and its metabolite 3,4-dihydroxyphenylacetic acid (DOPAC; Item No. 24912) in rats when administered intraperitoneally at a dose of 0.25 mg/kg.{52359} 7-hydroxy DPAT (2 µg/µl for eight weeks, i.c.v.) reduces the loss of ipsilateral substantia nigra pars compacta (SNC) dopaminergic neurons in a rat model of Parkinson’s disease induced by 6-OHDA (Item No. 25330).{52360} It also decreases amphetamine-induced ipsilateral rotations and increases the number of steps reached with the contralateral paw in the staircase test in the same model.
Brand:CaymanSKU:29516 - 5 mgAvailable on backorder
7-hydroxy Mitragynine (Item No. 13114) is an analytical reference standard that is structurally categorized as an opioid. It is an active metabolite of mitragynine (Item Nos. 18567 | 11151) that can be detected in urine.{33910} It is an agonist at the µ-opioid receptor (pD2 = 8.20), with a potency 13- and 46-fold higher than morphine and mitragynine, respectively.{20202} This product is intended for research and forensic applications.
Brand:CaymanSKU:-
7-hydroxy Pestalotin is a fungal metabolite originally isolated from Penicillium.{49001} It is phytotoxic against evening primrose, prickly sida, johnsongrass, morning glory, lambsquarter, and A. abla.{49002}
Brand:CaymanSKU:26523 - 2.5 mgAvailable on backorder
7-hydroxy Pestalotin is a fungal metabolite originally isolated from Penicillium.{49001} It is phytotoxic against evening primrose, prickly sida, johnsongrass, morning glory, lambsquarter, and A. abla.{49002}
Brand:CaymanSKU:26523 - 500 µgAvailable on backorder
7-hydroxy Warfarin is a metabolite of (-)-warfarin (Item No. 13531), which is a more potent vitamin K antagonist than (+)-warfarin (Item No. 13526).{39027,17423} Both isomers of warfarin are metabolized by the cytochrome P450 isoform 2C9 (CYP2C9). Stereoselective metabolism also occurs, and CYP2C9 is the primary enzyme responsible for metabolism of (-)-warfarin to 7-hydroxy warfarin.{39027}
Brand:CaymanSKU:9000672 - 1 mgAvailable on backorder
7-hydroxy Warfarin is a metabolite of (-)-warfarin (Item No. 13531), which is a more potent vitamin K antagonist than (+)-warfarin (Item No. 13526).{39027,17423} Both isomers of warfarin are metabolized by the cytochrome P450 isoform 2C9 (CYP2C9). Stereoselective metabolism also occurs, and CYP2C9 is the primary enzyme responsible for metabolism of (-)-warfarin to 7-hydroxy warfarin.{39027}
Brand:CaymanSKU:9000672 - 10 mgAvailable on backorder
7-hydroxy Warfarin is a metabolite of (-)-warfarin (Item No. 13531), which is a more potent vitamin K antagonist than (+)-warfarin (Item No. 13526).{39027,17423} Both isomers of warfarin are metabolized by the cytochrome P450 isoform 2C9 (CYP2C9). Stereoselective metabolism also occurs, and CYP2C9 is the primary enzyme responsible for metabolism of (-)-warfarin to 7-hydroxy warfarin.{39027}
Brand:CaymanSKU:9000672 - 5 mgAvailable on backorder
7-hydroxy Warfarin is a metabolite of (-)-warfarin (Item No. 13531), which is a more potent vitamin K antagonist than (+)-warfarin (Item No. 13526).{39027,17423} Both isomers of warfarin are metabolized by the cytochrome P450 isoform 2C9 (CYP2C9). Stereoselective metabolism also occurs, and CYP2C9 is the primary enzyme responsible for metabolism of (-)-warfarin to 7-hydroxy warfarin.{39027}
Brand:CaymanSKU:9000672 - 500 µgAvailable on backorder
7-Hydroxy-4-methyl-8-nitrocoumarin is a coumarin derivative with antibacterial and antioxidant activities.{53822,53821} It is active against S. aureus and E. coli in a disc assay when used at concentrations of 50 and 100 µg/disc.{53822} 7-Hydroxy-4-methyl-8-nitrocoumarin inhibits NADPH-dependent lipid peroxidation in rat liver microsomes.{53821}
Brand:CaymanSKU:30900 - 500 mgAvailable on backorder
7-hydroxycoumarinyl Arachidonate is the arachidonic acid ester of 7-hydroxycoumarin (umbelliferone) and behaves as a substrate for cPLA2. Hydrolysis of 7-hydroxycoumarinyl arachidonate by phospholipase results in the release of the fluorescent compound 7-hydroxycoumarin which can be monitored spectrophotometrically (excitation at 335 nm, emission at 450 nm).{1743,3042}
Brand:CaymanSKU:62910 - 10 mgAvailable on backorder
7-hydroxycoumarinyl Arachidonate is the arachidonic acid ester of 7-hydroxycoumarin (umbelliferone) and behaves as a substrate for cPLA2. Hydrolysis of 7-hydroxycoumarinyl arachidonate by phospholipase results in the release of the fluorescent compound 7-hydroxycoumarin which can be monitored spectrophotometrically (excitation at 335 nm, emission at 450 nm).{1743,3042}
Brand:CaymanSKU:62910 - 25 mgAvailable on backorder
7-hydroxycoumarinyl Arachidonate is the arachidonic acid ester of 7-hydroxycoumarin (umbelliferone) and behaves as a substrate for cPLA2. Hydrolysis of 7-hydroxycoumarinyl arachidonate by phospholipase results in the release of the fluorescent compound 7-hydroxycoumarin which can be monitored spectrophotometrically (excitation at 335 nm, emission at 450 nm).{1743,3042}
Brand:CaymanSKU:62910 - 5 mgAvailable on backorder
7-hydroxycoumarinyl Arachidonate is the arachidonic acid ester of 7-hydroxycoumarin (umbelliferone) and behaves as a substrate for cPLA2. Hydrolysis of 7-hydroxycoumarinyl arachidonate by phospholipase results in the release of the fluorescent compound 7-hydroxycoumarin which can be monitored spectrophotometrically (excitation at 335 nm, emission at 450 nm).{1743,3042}
Brand:CaymanSKU:62910 - 50 mgAvailable on backorder
7-hydroxycoumarinyl-γ-Linolenate is a γ-linolenic acid ester of 7-hydroxycoumarin (umbelliferone) that behaves as a substrate for cPLA2. Hydrolysis of 7-hydroxycoumarinyl-γ-linolenate by phospholipase results in the release of the fluorescent compound 7-hydroxycoumarin which can be monitored spectrophotometrically (excitation at 335 nm, emission at 450 nm).{1743}
Brand:CaymanSKU:10556 - 10 mgAvailable on backorder
7-hydroxycoumarinyl-γ-Linolenate is a γ-linolenic acid ester of 7-hydroxycoumarin (umbelliferone) that behaves as a substrate for cPLA2. Hydrolysis of 7-hydroxycoumarinyl-γ-linolenate by phospholipase results in the release of the fluorescent compound 7-hydroxycoumarin which can be monitored spectrophotometrically (excitation at 335 nm, emission at 450 nm).{1743}
Brand:CaymanSKU:10556 - 25 mgAvailable on backorder
7-hydroxycoumarinyl-γ-Linolenate is a γ-linolenic acid ester of 7-hydroxycoumarin (umbelliferone) that behaves as a substrate for cPLA2. Hydrolysis of 7-hydroxycoumarinyl-γ-linolenate by phospholipase results in the release of the fluorescent compound 7-hydroxycoumarin which can be monitored spectrophotometrically (excitation at 335 nm, emission at 450 nm).{1743}
Brand:CaymanSKU:10556 - 5 mgAvailable on backorder