Cayman
Showing 6451–6600 of 45550 results
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Brand:CaymanSKU:10007134 - 250 mgAvailable on backorder
Brand:CaymanSKU:10007134 - 50 mgAvailable on backorder
Brand:CaymanSKU:10007134 - 500 mgAvailable on backorder
5-Bromouridine is a brominated analog of the nucleoside uridine (Item No. 20300).{46879} It can be incorporated into RNA and subsequently detected by antibodies against bromodeoxyuridine (Item No. 15580).{46880} 5-Bromouridine decreases the viability of HL-60 and MOLT-4 cells (LC50s = 10 and 20 μM, respectively). It induces apoptosis and halts the cell cycle at the S phase in HL-60 cells. It is photoreactive, and UV irradiation has been used to cross-link RNA containing 5-bromouridine to proteins in the study of of RNA-protein interactions.{46879,46881} 5-Bromouridine can also be incorporated into RNA using 5-bromouridine 5’-triphosphate (Item No. 18140).
Brand:CaymanSKU:30457 - 1 gAvailable on backorder
5-Bromouridine is a brominated analog of the nucleoside uridine (Item No. 20300).{46879} It can be incorporated into RNA and subsequently detected by antibodies against bromodeoxyuridine (Item No. 15580).{46880} 5-Bromouridine decreases the viability of HL-60 and MOLT-4 cells (LC50s = 10 and 20 μM, respectively). It induces apoptosis and halts the cell cycle at the S phase in HL-60 cells. It is photoreactive, and UV irradiation has been used to cross-link RNA containing 5-bromouridine to proteins in the study of of RNA-protein interactions.{46879,46881} 5-Bromouridine can also be incorporated into RNA using 5-bromouridine 5’-triphosphate (Item No. 18140).
Brand:CaymanSKU:30457 - 500 mgAvailable on backorder
5-Butyl-4-[2,3-difluoro-4-(phenylmethoxy)phenyl]-6-phenyl-2-pyrimidinamine is an inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1; IC50s = 66 and 2,730 nM for the human and mouse enzymes, respectively).{52747} It is selective for mPGES-1 over COX-1 but does inhibit COX-2 at 20 µM. It also inhibits LPS-induced prostaglandin E2 (PGE2; Item No. 14010) production in mouse peritoneal cells (IC50 = 12 nM). In vivo, 5-butyl-4-[2,3-difluoro-4-(phenylmethoxy)phenyl]-6-phenyl-2-pyrimidinamine (25 mg/kg) reduces carrageenan-induced paw edema in rats.
Brand:CaymanSKU:31338 - 1 mgAvailable on backorder
5-Butyl-4-[2,3-difluoro-4-(phenylmethoxy)phenyl]-6-phenyl-2-pyrimidinamine is an inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1; IC50s = 66 and 2,730 nM for the human and mouse enzymes, respectively).{52747} It is selective for mPGES-1 over COX-1 but does inhibit COX-2 at 20 µM. It also inhibits LPS-induced prostaglandin E2 (PGE2; Item No. 14010) production in mouse peritoneal cells (IC50 = 12 nM). In vivo, 5-butyl-4-[2,3-difluoro-4-(phenylmethoxy)phenyl]-6-phenyl-2-pyrimidinamine (25 mg/kg) reduces carrageenan-induced paw edema in rats.
Brand:CaymanSKU:31338 - 250 µgAvailable on backorder
5-Butyl-4-[2,3-difluoro-4-(phenylmethoxy)phenyl]-6-phenyl-2-pyrimidinamine is an inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1; IC50s = 66 and 2,730 nM for the human and mouse enzymes, respectively).{52747} It is selective for mPGES-1 over COX-1 but does inhibit COX-2 at 20 µM. It also inhibits LPS-induced prostaglandin E2 (PGE2; Item No. 14010) production in mouse peritoneal cells (IC50 = 12 nM). In vivo, 5-butyl-4-[2,3-difluoro-4-(phenylmethoxy)phenyl]-6-phenyl-2-pyrimidinamine (25 mg/kg) reduces carrageenan-induced paw edema in rats.
Brand:CaymanSKU:31338 - 500 µgAvailable on backorder
5-Butyl-4-phenyl-6-[4-(phenylmethoxy)phenyl]-2-pyrimidinamine is an inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1; IC50s = 117 and 60 nM for the human and mouse enzymes, respectively).{52747} It inhibits LPS-induced prostaglandin E2 (PGE2; Item No. 14010) production in mouse peritoneal cells (IC50 = 31 nM). In vivo, 5-Butyl-4-phenyl-6-[4-(phenylmethoxy)phenyl]-2-pyrimidinamine (25 mg/kg) reduces carrageenan-induced paw edema in rats.
Brand:CaymanSKU:31337 - 1 mgAvailable on backorder
5-Butyl-4-phenyl-6-[4-(phenylmethoxy)phenyl]-2-pyrimidinamine is an inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1; IC50s = 117 and 60 nM for the human and mouse enzymes, respectively).{52747} It inhibits LPS-induced prostaglandin E2 (PGE2; Item No. 14010) production in mouse peritoneal cells (IC50 = 31 nM). In vivo, 5-Butyl-4-phenyl-6-[4-(phenylmethoxy)phenyl]-2-pyrimidinamine (25 mg/kg) reduces carrageenan-induced paw edema in rats.
Brand:CaymanSKU:31337 - 250 µgAvailable on backorder
5-Butyl-4-phenyl-6-[4-(phenylmethoxy)phenyl]-2-pyrimidinamine is an inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1; IC50s = 117 and 60 nM for the human and mouse enzymes, respectively).{52747} It inhibits LPS-induced prostaglandin E2 (PGE2; Item No. 14010) production in mouse peritoneal cells (IC50 = 31 nM). In vivo, 5-Butyl-4-phenyl-6-[4-(phenylmethoxy)phenyl]-2-pyrimidinamine (25 mg/kg) reduces carrageenan-induced paw edema in rats.
Brand:CaymanSKU:31337 - 500 µgAvailable on backorder
5-Caffeoylquinic acid (5-CQA) is a phenolic compound that has been found in M. domestica and has diverse biological activities, including antioxidant, anti-inflammatory, and antidiabetic properties.{36748,36749,36750,36751} 5-CQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805; EC50 = 0.184 mg/ml) and 2,2ʹ-azobis(2-amidinopropane) dihydrochloride (AAPH; Item No. 82235) radicals in cell-free assays (IC50 = 0.124 mg/ml).{36748} It decreases IL-6 and TNF-α levels in serum and macrophage infiltration into epididymal adipose tissue in rats fed a high-fat diet when administered at a dose of 90 mg/kg per day.{36750} 5-CQA (90 mg/kg per day) also decreases serum and liver free fatty acid (FFA) levels and lowers blood glucose level in an oral glucose tolerance test in high-fat diet-fed rats.{36751}
Brand:CaymanSKU:25054 - 10 mgAvailable on backorder
5-Caffeoylquinic acid (5-CQA) is a phenolic compound that has been found in M. domestica and has diverse biological activities, including antioxidant, anti-inflammatory, and antidiabetic properties.{36748,36749,36750,36751} 5-CQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805; EC50 = 0.184 mg/ml) and 2,2ʹ-azobis(2-amidinopropane) dihydrochloride (AAPH; Item No. 82235) radicals in cell-free assays (IC50 = 0.124 mg/ml).{36748} It decreases IL-6 and TNF-α levels in serum and macrophage infiltration into epididymal adipose tissue in rats fed a high-fat diet when administered at a dose of 90 mg/kg per day.{36750} 5-CQA (90 mg/kg per day) also decreases serum and liver free fatty acid (FFA) levels and lowers blood glucose level in an oral glucose tolerance test in high-fat diet-fed rats.{36751}
Brand:CaymanSKU:25054 - 25 mgAvailable on backorder
5-Caffeoylquinic acid (5-CQA) is a phenolic compound that has been found in M. domestica and has diverse biological activities, including antioxidant, anti-inflammatory, and antidiabetic properties.{36748,36749,36750,36751} 5-CQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805; EC50 = 0.184 mg/ml) and 2,2ʹ-azobis(2-amidinopropane) dihydrochloride (AAPH; Item No. 82235) radicals in cell-free assays (IC50 = 0.124 mg/ml).{36748} It decreases IL-6 and TNF-α levels in serum and macrophage infiltration into epididymal adipose tissue in rats fed a high-fat diet when administered at a dose of 90 mg/kg per day.{36750} 5-CQA (90 mg/kg per day) also decreases serum and liver free fatty acid (FFA) levels and lowers blood glucose level in an oral glucose tolerance test in high-fat diet-fed rats.{36751}
Brand:CaymanSKU:25054 - 5 mgAvailable on backorder
5-Caffeoylquinic acid (5-CQA) is a phenolic compound that has been found in M. domestica and has diverse biological activities, including antioxidant, anti-inflammatory, and antidiabetic properties.{36748,36749,36750,36751} 5-CQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805; EC50 = 0.184 mg/ml) and 2,2ʹ-azobis(2-amidinopropane) dihydrochloride (AAPH; Item No. 82235) radicals in cell-free assays (IC50 = 0.124 mg/ml).{36748} It decreases IL-6 and TNF-α levels in serum and macrophage infiltration into epididymal adipose tissue in rats fed a high-fat diet when administered at a dose of 90 mg/kg per day.{36750} 5-CQA (90 mg/kg per day) also decreases serum and liver free fatty acid (FFA) levels and lowers blood glucose level in an oral glucose tolerance test in high-fat diet-fed rats.{36751}
Brand:CaymanSKU:25054 - 50 mgAvailable on backorder
5-Carboxyfluorescein is a single isomer derivative of 5(6)-carboxyfluorescein (Item No. 17172) that can be used to fluorescently label biomolecules through the interaction of carboxylic acid with primary amines.{13893} It demonstrates excitation/emission maxima of 492 and 518 nm, respectively.
Brand:CaymanSKU:19581 -Available on backorder
5-Carboxyfluorescein is a single isomer derivative of 5(6)-carboxyfluorescein (Item No. 17172) that can be used to fluorescently label biomolecules through the interaction of carboxylic acid with primary amines.{13893} It demonstrates excitation/emission maxima of 492 and 518 nm, respectively.
Brand:CaymanSKU:19581 -Available on backorder
5-Carboxyfluorescein is a single isomer derivative of 5(6)-carboxyfluorescein (Item No. 17172) that can be used to fluorescently label biomolecules through the interaction of carboxylic acid with primary amines.{13893} It demonstrates excitation/emission maxima of 492 and 518 nm, respectively.
Brand:CaymanSKU:19581 -Available on backorder
5-Carboxyfluorescein is a single isomer derivative of 5(6)-carboxyfluorescein (Item No. 17172) that can be used to fluorescently label biomolecules through the interaction of carboxylic acid with primary amines.{13893} It demonstrates excitation/emission maxima of 492 and 518 nm, respectively.
Brand:CaymanSKU:19581 -Available on backorder
5-Carboxytetramethylrhodamine succinimidyl ester (5-TAMRA-SE) is an amine-reactive fluorescent probe.{53090} It has been used in double site-directed peptide modification to label proteinase substrates for use in FRET assays. It quenches lucifer yellow CH (Item No. 25573) fluorescence by greater than 90% in uncleaved proteinase substrates, which allows for the detection of enzyme-cleaved substrates by an increase in fluorescence intensity. It has also been used in the synthesis of fluorescent derivatives of a variety of compounds, including the antibiotic ampicillin (Item No. 14417), nucleotide diphosphate uridine-5’-diphosphate (UDP; Item No. 18137), and the progesterone receptor antagonist RU486 (mifepristone; Item No. 10006317).{53091,53092,53093} 5-TAMRA-SE displays excitation maxima ranging from 540 to 560 nm and an emission maximum of 580 nm.{53090}
Brand:CaymanSKU:28509 - 1 mgAvailable on backorder
5-Carboxytetramethylrhodamine succinimidyl ester (5-TAMRA-SE) is an amine-reactive fluorescent probe.{53090} It has been used in double site-directed peptide modification to label proteinase substrates for use in FRET assays. It quenches lucifer yellow CH (Item No. 25573) fluorescence by greater than 90% in uncleaved proteinase substrates, which allows for the detection of enzyme-cleaved substrates by an increase in fluorescence intensity. It has also been used in the synthesis of fluorescent derivatives of a variety of compounds, including the antibiotic ampicillin (Item No. 14417), nucleotide diphosphate uridine-5’-diphosphate (UDP; Item No. 18137), and the progesterone receptor antagonist RU486 (mifepristone; Item No. 10006317).{53091,53092,53093} 5-TAMRA-SE displays excitation maxima ranging from 540 to 560 nm and an emission maximum of 580 nm.{53090}
Brand:CaymanSKU:28509 - 10 mgAvailable on backorder
5-Carboxytetramethylrhodamine succinimidyl ester (5-TAMRA-SE) is an amine-reactive fluorescent probe.{53090} It has been used in double site-directed peptide modification to label proteinase substrates for use in FRET assays. It quenches lucifer yellow CH (Item No. 25573) fluorescence by greater than 90% in uncleaved proteinase substrates, which allows for the detection of enzyme-cleaved substrates by an increase in fluorescence intensity. It has also been used in the synthesis of fluorescent derivatives of a variety of compounds, including the antibiotic ampicillin (Item No. 14417), nucleotide diphosphate uridine-5’-diphosphate (UDP; Item No. 18137), and the progesterone receptor antagonist RU486 (mifepristone; Item No. 10006317).{53091,53092,53093} 5-TAMRA-SE displays excitation maxima ranging from 540 to 560 nm and an emission maximum of 580 nm.{53090}
Brand:CaymanSKU:28509 - 25 mgAvailable on backorder
5-Carboxytetramethylrhodamine succinimidyl ester (5-TAMRA-SE) is an amine-reactive fluorescent probe.{53090} It has been used in double site-directed peptide modification to label proteinase substrates for use in FRET assays. It quenches lucifer yellow CH (Item No. 25573) fluorescence by greater than 90% in uncleaved proteinase substrates, which allows for the detection of enzyme-cleaved substrates by an increase in fluorescence intensity. It has also been used in the synthesis of fluorescent derivatives of a variety of compounds, including the antibiotic ampicillin (Item No. 14417), nucleotide diphosphate uridine-5’-diphosphate (UDP; Item No. 18137), and the progesterone receptor antagonist RU486 (mifepristone; Item No. 10006317).{53091,53092,53093} 5-TAMRA-SE displays excitation maxima ranging from 540 to 560 nm and an emission maximum of 580 nm.{53090}
Brand:CaymanSKU:28509 - 5 mgAvailable on backorder
AB-PINACA (Item No. 14038) is a synthetic cannabinoid recently identified in illegal herbal products.{22006} Structurally, this designer drug is developed on an indazole base, which distinguishes it from the many JWH compounds having an indolyl base.{22006,18232} 5-chloro AB-PINACA is a derivative of AB-PINACA featuring a chlorine atom added to the terminal carbon of the pentyl group. The physiological and toxicological properties of this compound have not been determined. This product is intended for research and forensic applications.
Brand:CaymanSKU:9001857 - 1 mgAvailable on backorder
AB-PINACA (Item No. 14038) is a synthetic cannabinoid recently identified in illegal herbal products.{22006} Structurally, this designer drug is developed on an indazole base, which distinguishes it from the many JWH compounds having an indolyl base.{22006,18232} 5-chloro AB-PINACA is a derivative of AB-PINACA featuring a chlorine atom added to the terminal carbon of the pentyl group. The physiological and toxicological properties of this compound have not been determined. This product is intended for research and forensic applications.
Brand:CaymanSKU:9001857 - 10 mgAvailable on backorder
AB-PINACA (Item No. 14038) is a synthetic cannabinoid recently identified in illegal herbal products.{22006} Structurally, this designer drug is developed on an indazole base, which distinguishes it from the many JWH compounds having an indolyl base.{22006,18232} 5-chloro AB-PINACA is a derivative of AB-PINACA featuring a chlorine atom added to the terminal carbon of the pentyl group. The physiological and toxicological properties of this compound have not been determined. This product is intended for research and forensic applications.
Brand:CaymanSKU:9001857 - 5 mgAvailable on backorder
5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.{28629,28630}
Brand:CaymanSKU:-Available on backorder
5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.{28629,28630}
Brand:CaymanSKU:-Available on backorder
5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.{28629,28630}
Brand:CaymanSKU:-Available on backorder
NNEI (Item No. 15001) is an analog of the potent synthetic cannabinoid JWH 018 (Item No. 10900) which differs by having an amide linker inserted between the naphthalene and ketone groups. 5-chloro NNEI is a derivative of NNEI that has a chloride atom added to the terminal carbon of the pentyl group. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:- NNEI (Item No. 15001) is an analog of the potent synthetic cannabinoid JWH 018 (Item No. 10900) which differs by having an amide linker inserted between the naphthalene and ketone groups. 5-chloro NNEI is a derivative of NNEI that has a chloride atom added to the terminal carbon of the pentyl group. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:- NNEI (Item No. 15001) is an analog of the potent synthetic cannabinoid JWH 018 (Item No. 10900) which differs by having an amide linker inserted between the naphthalene and ketone groups. 5-chloro NNEI is a derivative of NNEI that has a chloride atom added to the terminal carbon of the pentyl group. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:-
5-chloro Tryptamine (hydrochloride) (Item No. 32707) is an analytical reference standard categorized as a tryptamine.{61118} It is a precursor in the synthesis of 5-chloro-N,N-DMT. This product is intended for research and forensic applications.
Brand:CaymanSKU:32707 - 1 mgAvailable on backorder
5-chloro Tryptamine (hydrochloride) (Item No. 32707) is an analytical reference standard categorized as a tryptamine.{61118} It is a precursor in the synthesis of 5-chloro-N,N-DMT. This product is intended for research and forensic applications.
Brand:CaymanSKU:32707 - 5 mgAvailable on backorder
5-Chloro-2′-deoxyuridine (CldU) is a thymidine analog that is readily incorporated, following phosphorylation, into newly synthesized DNA in place of thymidine.{29384} Like 5-bromo-2’-deoxyuridine (Item No. 15580) and 5-iodo-2’-deoxyuridine, CldU can be detected immunologically in cells and tissues.{29386,29381} CldU can also be added to cells or tissues sequentially with another thymidine analog to label temporally distinct populations.{29383,29385} The insertion of thymidine analogs, including CldU, can significantly alter DNA processing and replication, so these analogs have also been used as mutagens, clastogens, and antiviral compounds.{29384,29382}
Brand:CaymanSKU:-Available on backorder
5-Chloro-2′-deoxyuridine (CldU) is a thymidine analog that is readily incorporated, following phosphorylation, into newly synthesized DNA in place of thymidine.{29384} Like 5-bromo-2’-deoxyuridine (Item No. 15580) and 5-iodo-2’-deoxyuridine, CldU can be detected immunologically in cells and tissues.{29386,29381} CldU can also be added to cells or tissues sequentially with another thymidine analog to label temporally distinct populations.{29383,29385} The insertion of thymidine analogs, including CldU, can significantly alter DNA processing and replication, so these analogs have also been used as mutagens, clastogens, and antiviral compounds.{29384,29382}
Brand:CaymanSKU:-Available on backorder
5-Chloro-2′-deoxyuridine (CldU) is a thymidine analog that is readily incorporated, following phosphorylation, into newly synthesized DNA in place of thymidine.{29384} Like 5-bromo-2’-deoxyuridine (Item No. 15580) and 5-iodo-2’-deoxyuridine, CldU can be detected immunologically in cells and tissues.{29386,29381} CldU can also be added to cells or tissues sequentially with another thymidine analog to label temporally distinct populations.{29383,29385} The insertion of thymidine analogs, including CldU, can significantly alter DNA processing and replication, so these analogs have also been used as mutagens, clastogens, and antiviral compounds.{29384,29382}
Brand:CaymanSKU:-Available on backorder
Brand:CaymanSKU:10007127 - 10 gAvailable on backorder
Brand:CaymanSKU:10007127 - 25 gAvailable on backorder
Brand:CaymanSKU:10007127 - 5 gAvailable on backorder
Brand:CaymanSKU:10007127 - 50 gAvailable on backorder
5-Chlorouracil is a chlorinated derivative of the pyrimidine nucleoside base uracil (Item No. 26088). In vivo, it is converted into chlorodeoxyuridine, which is mutagenic and genotoxic.{46329} Uracil is chlorinated at the 5 position in a cell-free myeloperoxidase, peroxide, and chloride system in which hypochlorous acid is formed.{46330} 5-Chlorouracil has been found in human neutrophils stimulated with phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) in vitro and in inflammatory human exudate isolated from sites of superficial infection. Levels of 5-chlorouracil are increased in exudate isolated from the site of inflammation in a rat model of carrageenan-induced inflammation and in patient-derived human atherosclerotic aortic tissue.{46331,46332}
Brand:CaymanSKU:27790 - 10 gAvailable on backorder
5-Chlorouracil is a chlorinated derivative of the pyrimidine nucleoside base uracil (Item No. 26088). In vivo, it is converted into chlorodeoxyuridine, which is mutagenic and genotoxic.{46329} Uracil is chlorinated at the 5 position in a cell-free myeloperoxidase, peroxide, and chloride system in which hypochlorous acid is formed.{46330} 5-Chlorouracil has been found in human neutrophils stimulated with phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) in vitro and in inflammatory human exudate isolated from sites of superficial infection. Levels of 5-chlorouracil are increased in exudate isolated from the site of inflammation in a rat model of carrageenan-induced inflammation and in patient-derived human atherosclerotic aortic tissue.{46331,46332}
Brand:CaymanSKU:27790 - 25 gAvailable on backorder
5-Chlorouracil is a chlorinated derivative of the pyrimidine nucleoside base uracil (Item No. 26088). In vivo, it is converted into chlorodeoxyuridine, which is mutagenic and genotoxic.{46329} Uracil is chlorinated at the 5 position in a cell-free myeloperoxidase, peroxide, and chloride system in which hypochlorous acid is formed.{46330} 5-Chlorouracil has been found in human neutrophils stimulated with phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) in vitro and in inflammatory human exudate isolated from sites of superficial infection. Levels of 5-chlorouracil are increased in exudate isolated from the site of inflammation in a rat model of carrageenan-induced inflammation and in patient-derived human atherosclerotic aortic tissue.{46331,46332}
Brand:CaymanSKU:27790 - 5 gAvailable on backorder
5-Chlorouracil is a chlorinated derivative of the pyrimidine nucleoside base uracil (Item No. 26088). In vivo, it is converted into chlorodeoxyuridine, which is mutagenic and genotoxic.{46329} Uracil is chlorinated at the 5 position in a cell-free myeloperoxidase, peroxide, and chloride system in which hypochlorous acid is formed.{46330} 5-Chlorouracil has been found in human neutrophils stimulated with phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) in vitro and in inflammatory human exudate isolated from sites of superficial infection. Levels of 5-chlorouracil are increased in exudate isolated from the site of inflammation in a rat model of carrageenan-induced inflammation and in patient-derived human atherosclerotic aortic tissue.{46331,46332}
Brand:CaymanSKU:27790 - 50 gAvailable on backorder
5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin. It is a weak inhibitor of human platelet aggregation with an IC50 of 2.8 µM compared to 0.3 µM for carbaprostacyclin.{509,3320} 5-cis Carbaprostacyclin is a much weaker effector of rabbit mesenteric artery relaxation with an EC50 of 104 µM compared to 5.9 µM for carbaprostacyclin. It even antagonizes the adenylate cyclase activation induced by carbaprostacyclin.{3320}
Brand:CaymanSKU:-Available on backorder
5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin. It is a weak inhibitor of human platelet aggregation with an IC50 of 2.8 µM compared to 0.3 µM for carbaprostacyclin.{509,3320} 5-cis Carbaprostacyclin is a much weaker effector of rabbit mesenteric artery relaxation with an EC50 of 104 µM compared to 5.9 µM for carbaprostacyclin. It even antagonizes the adenylate cyclase activation induced by carbaprostacyclin.{3320}
Brand:CaymanSKU:-Available on backorder
5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin. It is a weak inhibitor of human platelet aggregation with an IC50 of 2.8 µM compared to 0.3 µM for carbaprostacyclin.{509,3320} 5-cis Carbaprostacyclin is a much weaker effector of rabbit mesenteric artery relaxation with an EC50 of 104 µM compared to 5.9 µM for carbaprostacyclin. It even antagonizes the adenylate cyclase activation induced by carbaprostacyclin.{3320}
Brand:CaymanSKU:-Available on backorder
5-cis Iloprost is the C-5 cis-isomer of iloprost, a second generation structural analog of prostaglandin I2 (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable prostacyclin analogs, typified by carbaprostacyclin.{3347} There are no published studies of the pharmacological properties of 5-cis iloprost.
Brand:CaymanSKU:10008585 - 1 mgAvailable on backorder
5-cis Iloprost is the C-5 cis-isomer of iloprost, a second generation structural analog of prostaglandin I2 (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable prostacyclin analogs, typified by carbaprostacyclin.{3347} There are no published studies of the pharmacological properties of 5-cis iloprost.
Brand:CaymanSKU:10008585 - 10 mgAvailable on backorder
5-cis Iloprost is the C-5 cis-isomer of iloprost, a second generation structural analog of prostaglandin I2 (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable prostacyclin analogs, typified by carbaprostacyclin.{3347} There are no published studies of the pharmacological properties of 5-cis iloprost.
Brand:CaymanSKU:10008585 - 5 mgAvailable on backorder
5-cis Iloprost is the C-5 cis-isomer of iloprost, a second generation structural analog of prostaglandin I2 (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable prostacyclin analogs, typified by carbaprostacyclin.{3347} There are no published studies of the pharmacological properties of 5-cis iloprost.
Brand:CaymanSKU:10008585 - 500 µgAvailable on backorder
5-Cyano-2,3-di-(p-tolyl)tetrazolium (chloride) is a redox-sensitive tetrazolium salt used primarily to detect metabolic activity in microorganisms.{25823,25821,25822} This membrane-permeable indicator is readily taken up by living cells and reduced by respiratory activity to produce a red fluorescent, water-insoluble formazan crystal (absorption maximum at 450 nm).{25822,25820} While the oxidized salt is non-fluorescent, the reduced formazan can be evaluated using a standard rhodamine filter set (excitation: 510-560 nm; emission > 590 nm), although optimum excitation requires a blue 420 nm excitation filter.{25823,25821} For flow cytometry, a 480 nm excitation laser combined with detection in the red region is suitable.
Brand:CaymanSKU:- 5-Cyano-2,3-di-(p-tolyl)tetrazolium (chloride) is a redox-sensitive tetrazolium salt used primarily to detect metabolic activity in microorganisms.{25823,25821,25822} This membrane-permeable indicator is readily taken up by living cells and reduced by respiratory activity to produce a red fluorescent, water-insoluble formazan crystal (absorption maximum at 450 nm).{25822,25820} While the oxidized salt is non-fluorescent, the reduced formazan can be evaluated using a standard rhodamine filter set (excitation: 510-560 nm; emission > 590 nm), although optimum excitation requires a blue 420 nm excitation filter.{25823,25821} For flow cytometry, a 480 nm excitation laser combined with detection in the red region is suitable.
Brand:CaymanSKU:- 5-Cyano-2,3-di-(p-tolyl)tetrazolium (chloride) is a redox-sensitive tetrazolium salt used primarily to detect metabolic activity in microorganisms.{25823,25821,25822} This membrane-permeable indicator is readily taken up by living cells and reduced by respiratory activity to produce a red fluorescent, water-insoluble formazan crystal (absorption maximum at 450 nm).{25822,25820} While the oxidized salt is non-fluorescent, the reduced formazan can be evaluated using a standard rhodamine filter set (excitation: 510-560 nm; emission > 590 nm), although optimum excitation requires a blue 420 nm excitation filter.{25823,25821} For flow cytometry, a 480 nm excitation laser combined with detection in the red region is suitable.
Brand:CaymanSKU:- 5-Cyano-2,3-di-(p-tolyl)tetrazolium (chloride) is a redox-sensitive tetrazolium salt used primarily to detect metabolic activity in microorganisms.{25823,25821,25822} This membrane-permeable indicator is readily taken up by living cells and reduced by respiratory activity to produce a red fluorescent, water-insoluble formazan crystal (absorption maximum at 450 nm).{25822,25820} While the oxidized salt is non-fluorescent, the reduced formazan can be evaluated using a standard rhodamine filter set (excitation: 510-560 nm; emission > 590 nm), although optimum excitation requires a blue 420 nm excitation filter.{25823,25821} For flow cytometry, a 480 nm excitation laser combined with detection in the red region is suitable.
Brand:CaymanSKU:-
5-deoxy-D-Ribose is a building block that has been used in the synthesis of carcinolytic compounds.{46846}
Brand:CaymanSKU:30103 - 100 mgAvailable on backorder
5-deoxy-D-Ribose is a building block that has been used in the synthesis of carcinolytic compounds.{46846}
Brand:CaymanSKU:30103 - 250 mgAvailable on backorder
5-deoxy-D-Ribose is a building block that has been used in the synthesis of carcinolytic compounds.{46846}
Brand:CaymanSKU:30103 - 50 mgAvailable on backorder
5-deoxy-D-Ribose is a building block that has been used in the synthesis of carcinolytic compounds.{46846}
Brand:CaymanSKU:30103 - 500 mgAvailable on backorder
5-APB (hydrochloride) (Item No. 11134) is a stimulant and entactogen belonging to the amphetamine class of psychoactive designer drugs.{22885} 5-EAPB is an analog of 5-APB that is characterized by an ethyl group added to the amine. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:- 5-APB (hydrochloride) (Item No. 11134) is a stimulant and entactogen belonging to the amphetamine class of psychoactive designer drugs.{22885} 5-EAPB is an analog of 5-APB that is characterized by an ethyl group added to the amine. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:- 5-APB (hydrochloride) (Item No. 11134) is a stimulant and entactogen belonging to the amphetamine class of psychoactive designer drugs.{22885} 5-EAPB is an analog of 5-APB that is characterized by an ethyl group added to the amine. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:-
5-Ethynyl-2′-deoxyuridine (EdU) is a nucleoside analog of thymidine that is used to monitor de novo DNA synthesis through click chemistry.{32475,32476} Like 5-bromo-2’-deoxyuridine (BrdU; Item No. 15580), EdU is incorporated into DNA during active DNA synthesis. It can then be detected using a fluorescent azide probe and copper catalysis using 1,3-dipolar cycloaddition.{32476} Modified nucleosides, including EdU, can be cytotoxic when added to cells for prolonged periods.{32477}
Brand:CaymanSKU:20518 -Available on backorder
5-Ethynyl-2′-deoxyuridine (EdU) is a nucleoside analog of thymidine that is used to monitor de novo DNA synthesis through click chemistry.{32475,32476} Like 5-bromo-2’-deoxyuridine (BrdU; Item No. 15580), EdU is incorporated into DNA during active DNA synthesis. It can then be detected using a fluorescent azide probe and copper catalysis using 1,3-dipolar cycloaddition.{32476} Modified nucleosides, including EdU, can be cytotoxic when added to cells for prolonged periods.{32477}
Brand:CaymanSKU:20518 -Available on backorder
5-Ethynyl-2′-deoxyuridine (EdU) is a nucleoside analog of thymidine that is used to monitor de novo DNA synthesis through click chemistry.{32475,32476} Like 5-bromo-2’-deoxyuridine (BrdU; Item No. 15580), EdU is incorporated into DNA during active DNA synthesis. It can then be detected using a fluorescent azide probe and copper catalysis using 1,3-dipolar cycloaddition.{32476} Modified nucleosides, including EdU, can be cytotoxic when added to cells for prolonged periods.{32477}
Brand:CaymanSKU:20518 -Available on backorder
5-Ethynyl-2′-deoxyuridine (EdU) is a nucleoside analog of thymidine that is used to monitor de novo DNA synthesis through click chemistry.{32475,32476} Like 5-bromo-2’-deoxyuridine (BrdU; Item No. 15580), EdU is incorporated into DNA during active DNA synthesis. It can then be detected using a fluorescent azide probe and copper catalysis using 1,3-dipolar cycloaddition.{32476} Modified nucleosides, including EdU, can be cytotoxic when added to cells for prolonged periods.{32477}
Brand:CaymanSKU:20518 -Available on backorder
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. 5-fluoro 203 is a cytotoxic compound that at 1 µM activates AhR signaling, inducing transcription of CYP1A1, which leads to the formation of DNA adducts and cell cycle arrest.{28854,28853,27489} In certain ovarian, breast, kidney, and colorectal cancer cells, 5-fluoro 203 can increase the levels of reactive oxygen species as well as activate JNK, ERK, and p38 MAPK.{28855}
Brand:CaymanSKU:-Available on backorder
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. 5-fluoro 203 is a cytotoxic compound that at 1 µM activates AhR signaling, inducing transcription of CYP1A1, which leads to the formation of DNA adducts and cell cycle arrest.{28854,28853,27489} In certain ovarian, breast, kidney, and colorectal cancer cells, 5-fluoro 203 can increase the levels of reactive oxygen species as well as activate JNK, ERK, and p38 MAPK.{28855}
Brand:CaymanSKU:-Available on backorder
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. 5-fluoro 203 is a cytotoxic compound that at 1 µM activates AhR signaling, inducing transcription of CYP1A1, which leads to the formation of DNA adducts and cell cycle arrest.{28854,28853,27489} In certain ovarian, breast, kidney, and colorectal cancer cells, 5-fluoro 203 can increase the levels of reactive oxygen species as well as activate JNK, ERK, and p38 MAPK.{28855}
Brand:CaymanSKU:-Available on backorder
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. 5-fluoro 203 is a cytotoxic compound that at 1 µM activates AhR signaling, inducing transcription of CYP1A1, which leads to the formation of DNA adducts and cell cycle arrest.{28854,28853,27489} In certain ovarian, breast, kidney, and colorectal cancer cells, 5-fluoro 203 can increase the levels of reactive oxygen species as well as activate JNK, ERK, and p38 MAPK.{28855}
Brand:CaymanSKU:-Available on backorder
5-fluoro AB-PINACA 3-carboxyindazole metabolite (Item No. 27733) is an analytical reference standard that is structurally similar to known synthetic cannabinoid metabolites. 5-fluoro AB-PINACA 3-carboxyindazole metabolite is a precursor in the synthesis of 5-fluoro AB-PINACA (Item No. 14755), 5-fluoro ADB-PINACA, (S)-5-fluoro ADB (Item Nos. 25012 | 23631), 5-fluoro AMB (Item No. 15489), and 5-fluoro CUMYL-PINACA (Item No. 17726).{30114,41223,48261} This product is intended for research and forensic applications.
Brand:CaymanSKU:27733 - 1 mgAvailable on backorder
5-fluoro AB-PINACA 3-carboxyindazole metabolite (Item No. 27733) is an analytical reference standard that is structurally similar to known synthetic cannabinoid metabolites. 5-fluoro AB-PINACA 3-carboxyindazole metabolite is a precursor in the synthesis of 5-fluoro AB-PINACA (Item No. 14755), 5-fluoro ADB-PINACA, (S)-5-fluoro ADB (Item Nos. 25012 | 23631), 5-fluoro AMB (Item No. 15489), and 5-fluoro CUMYL-PINACA (Item No. 17726).{30114,41223,48261} This product is intended for research and forensic applications.
Brand:CaymanSKU:27733 - 5 mgAvailable on backorder
5-fluoro AB-PINACA (Item No. 14755) is a synthetic cannabinoid featuring an aminoalkylindazole base. 5-fluoro ABICA is a homolog of 5-fluoro AB-PINACA that differs by having an indole group in place of the indazole group. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:9001555 - 1 mgAvailable on backorder
5-fluoro AB-PINACA (Item No. 14755) is a synthetic cannabinoid featuring an aminoalkylindazole base. 5-fluoro ABICA is a homolog of 5-fluoro AB-PINACA that differs by having an indole group in place of the indazole group. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:9001555 - 10 mgAvailable on backorder
5-fluoro AB-PINACA (Item No. 14755) is a synthetic cannabinoid featuring an aminoalkylindazole base. 5-fluoro ABICA is a homolog of 5-fluoro AB-PINACA that differs by having an indole group in place of the indazole group. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:9001555 - 5 mgAvailable on backorder
ADBICA is a synthetic cannabinoid that has recently been identified in herbal blends.{23290} 5-fluoro ADBICA is a derivative of ADBICA featuring a fluorine atom added to the terminal carbon of the pentyl group. The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:- ADBICA is a synthetic cannabinoid that has recently been identified in herbal blends.{23290} 5-fluoro ADBICA is a derivative of ADBICA featuring a fluorine atom added to the terminal carbon of the pentyl group. The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:- ADBICA is a synthetic cannabinoid that has recently been identified in herbal blends.{23290} 5-fluoro ADBICA is a derivative of ADBICA featuring a fluorine atom added to the terminal carbon of the pentyl group. The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:-
AKB48 is a pentyl indazole with structural similarity to JWH 018 adamantyl carboxamide (Item No. 9001193) and STS-135 (Item No. 11564), which are synthetic cannabinoids (CBs) with potential to be sold for recreational abuse.{22837} AKB48 N-(5-fluoropentyl) analog (Item No. 12065) is a structural derivative of AKB48 in which a fluorine atom has been added to the terminal carbon of the pentyl chain. This modification in other synthetic CBs typically increases the compound’s affinity for both CB receptors significantly.{18696} 5-fluoro AKB48 N-(4-hyroxypentyl) metabolite is an expected phase 1 metabolite of AKB48 N-(5-fluoropentyl) analog, based on the known metabolism of similar compounds.{19353} This product is intended for research and forensic applications.
Brand:CaymanSKU:- AKB48 is a pentyl indazole with structural similarity to JWH 018 adamantyl carboxamide (Item No. 9001193) and STS-135 (Item No. 11564), which are synthetic cannabinoids (CBs) with potential to be sold for recreational abuse.{22837} AKB48 N-(5-fluoropentyl) analog (Item No. 12065) is a structural derivative of AKB48 in which a fluorine atom has been added to the terminal carbon of the pentyl chain. This modification in other synthetic CBs typically increases the compound’s affinity for both CB receptors significantly.{18696} 5-fluoro AKB48 N-(4-hyroxypentyl) metabolite is an expected phase 1 metabolite of AKB48 N-(5-fluoropentyl) analog, based on the known metabolism of similar compounds.{19353} This product is intended for research and forensic applications.
Brand:CaymanSKU:-