Cayman

Showing 6001–6150 of 45550 results

  • 4-Hydroxymethamphetamine (hydrochloride) is an analytical reference standard categorized as an amphetamine. It is a metabolite of methamphetamine (Item Nos. 14216 | ISO60168).{47743} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:9002128 - 1 mg

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  • 4-Hydroxymethamphetamine (hydrochloride) is an analytical reference standard categorized as an amphetamine. It is a metabolite of methamphetamine (Item Nos. 14216 | ISO60168).{47743} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:9002128 - 5 mg

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  • 4-Hydroxyphenylacetic acid is a phenolic acid with anti-inflammatory activity.{46255} It is formed via microbial metabolism of aromatic amino acids and polyphenolic compounds, including flavonoid glycosides, by gut microbiota.{46256,46257,46258} 4-Hydroxyphenylacetic acid (100 mg/kg) inhibits seawater instillation-induced increases in TNF-α, IL-1β, and IL-6 levels in lung tissue and white blood cell numbers in bronchoalveolar lavage fluid (BALF) and prevents lung edema in a rat model of acute lung injury.{46255} Levels of 4-hydroxyphenylacetic acid are increased and decreased in serum and urine, respectively, in rats fed a high-fat diet.{46256} Serum levels of 4-hydroxyphenylacetic acid are increased in patients with stage III pancreatic cancer.{46259}  

     

    Brand:
    Cayman
    SKU:26613 - 100 g

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  • 4-Hydroxyphenylacetic acid is a phenolic acid with anti-inflammatory activity.{46255} It is formed via microbial metabolism of aromatic amino acids and polyphenolic compounds, including flavonoid glycosides, by gut microbiota.{46256,46257,46258} 4-Hydroxyphenylacetic acid (100 mg/kg) inhibits seawater instillation-induced increases in TNF-α, IL-1β, and IL-6 levels in lung tissue and white blood cell numbers in bronchoalveolar lavage fluid (BALF) and prevents lung edema in a rat model of acute lung injury.{46255} Levels of 4-hydroxyphenylacetic acid are increased and decreased in serum and urine, respectively, in rats fed a high-fat diet.{46256} Serum levels of 4-hydroxyphenylacetic acid are increased in patients with stage III pancreatic cancer.{46259}  

     

    Brand:
    Cayman
    SKU:26613 - 25 g

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  • 4-Hydroxyphenylacetic acid is a phenolic acid with anti-inflammatory activity.{46255} It is formed via microbial metabolism of aromatic amino acids and polyphenolic compounds, including flavonoid glycosides, by gut microbiota.{46256,46257,46258} 4-Hydroxyphenylacetic acid (100 mg/kg) inhibits seawater instillation-induced increases in TNF-α, IL-1β, and IL-6 levels in lung tissue and white blood cell numbers in bronchoalveolar lavage fluid (BALF) and prevents lung edema in a rat model of acute lung injury.{46255} Levels of 4-hydroxyphenylacetic acid are increased and decreased in serum and urine, respectively, in rats fed a high-fat diet.{46256} Serum levels of 4-hydroxyphenylacetic acid are increased in patients with stage III pancreatic cancer.{46259}  

     

    Brand:
    Cayman
    SKU:26613 - 250 g

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  • 4-Hydroxyphenylacetic acid is a phenolic acid with anti-inflammatory activity.{46255} It is formed via microbial metabolism of aromatic amino acids and polyphenolic compounds, including flavonoid glycosides, by gut microbiota.{46256,46257,46258} 4-Hydroxyphenylacetic acid (100 mg/kg) inhibits seawater instillation-induced increases in TNF-α, IL-1β, and IL-6 levels in lung tissue and white blood cell numbers in bronchoalveolar lavage fluid (BALF) and prevents lung edema in a rat model of acute lung injury.{46255} Levels of 4-hydroxyphenylacetic acid are increased and decreased in serum and urine, respectively, in rats fed a high-fat diet.{46256} Serum levels of 4-hydroxyphenylacetic acid are increased in patients with stage III pancreatic cancer.{46259}  

     

    Brand:
    Cayman
    SKU:26613 - 50 g

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  • 4-IBP is a sigma-1 (σ1) receptor ligand (Ki = 1.7 nM).{61020,61021} It is selective for σ1 over σ2 receptors (Ki = 25.2 nM). It inhibits the growth and migration of PC3 prostate cancer and A549 non-small cell lung cancer (NSCLC) cells, as well as the migration of C32 melanoma and U373 MG glioblastoma cells, when used at a concentration of 10 µM.{61020} 4-IBP (2 mg/kg) increases survival in a U373 MG mouse xenograft model. It also increases firing of serotonergic neurons in the rat dorsal raphe nucleus when administered at a dose of 2 mg/kg.{61021}  

     

    Brand:
    Cayman
    SKU:31518 - 10 mg

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  • 4-IBP is a sigma-1 (σ1) receptor ligand (Ki = 1.7 nM).{61020,61021} It is selective for σ1 over σ2 receptors (Ki = 25.2 nM). It inhibits the growth and migration of PC3 prostate cancer and A549 non-small cell lung cancer (NSCLC) cells, as well as the migration of C32 melanoma and U373 MG glioblastoma cells, when used at a concentration of 10 µM.{61020} 4-IBP (2 mg/kg) increases survival in a U373 MG mouse xenograft model. It also increases firing of serotonergic neurons in the rat dorsal raphe nucleus when administered at a dose of 2 mg/kg.{61021}  

     

    Brand:
    Cayman
    SKU:31518 - 25 mg

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  • 4-IBP is a sigma-1 (σ1) receptor ligand (Ki = 1.7 nM).{61020,61021} It is selective for σ1 over σ2 receptors (Ki = 25.2 nM). It inhibits the growth and migration of PC3 prostate cancer and A549 non-small cell lung cancer (NSCLC) cells, as well as the migration of C32 melanoma and U373 MG glioblastoma cells, when used at a concentration of 10 µM.{61020} 4-IBP (2 mg/kg) increases survival in a U373 MG mouse xenograft model. It also increases firing of serotonergic neurons in the rat dorsal raphe nucleus when administered at a dose of 2 mg/kg.{61021}  

     

    Brand:
    Cayman
    SKU:31518 - 5 mg

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  • 4-IBP is a sigma-1 (σ1) receptor ligand (Ki = 1.7 nM).{61020,61021} It is selective for σ1 over σ2 receptors (Ki = 25.2 nM). It inhibits the growth and migration of PC3 prostate cancer and A549 non-small cell lung cancer (NSCLC) cells, as well as the migration of C32 melanoma and U373 MG glioblastoma cells, when used at a concentration of 10 µM.{61020} 4-IBP (2 mg/kg) increases survival in a U373 MG mouse xenograft model. It also increases firing of serotonergic neurons in the rat dorsal raphe nucleus when administered at a dose of 2 mg/kg.{61021}  

     

    Brand:
    Cayman
    SKU:31518 - 50 mg

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  • 4-iodo-SAHA is a hydrophobic derivative of the class I and class II histone deacetylase (HDAC) inhibitor SAHA. At 1 μM it demonstrates >60% inhibition of HDAC1 and HDAC6 activity in a deacetylase activity assay, similar to that of SAHA. 4-iodo-SAHA inhibits proliferation of SK-BR-3 breast-derived and HT29 colon-derived cell lines with EC50 values comparable to that of SAHA (1.1 and 0.95 μM versus 2.1 and 2 μM, respectively). It is 10-fold more potent as an inhibitor of U937 leukemia cell proliferation compared to SAHA (0.12 μM versus 1.2 μM, respectively).{18112}  

     

    Brand:
    Cayman
    SKU:10495 - 100 mg

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  • 4-iodo-SAHA is a hydrophobic derivative of the class I and class II histone deacetylase (HDAC) inhibitor SAHA. At 1 μM it demonstrates >60% inhibition of HDAC1 and HDAC6 activity in a deacetylase activity assay, similar to that of SAHA. 4-iodo-SAHA inhibits proliferation of SK-BR-3 breast-derived and HT29 colon-derived cell lines with EC50 values comparable to that of SAHA (1.1 and 0.95 μM versus 2.1 and 2 μM, respectively). It is 10-fold more potent as an inhibitor of U937 leukemia cell proliferation compared to SAHA (0.12 μM versus 1.2 μM, respectively).{18112}  

     

    Brand:
    Cayman
    SKU:10495 - 250 mg

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  • 4-iodo-SAHA is a hydrophobic derivative of the class I and class II histone deacetylase (HDAC) inhibitor SAHA. At 1 μM it demonstrates >60% inhibition of HDAC1 and HDAC6 activity in a deacetylase activity assay, similar to that of SAHA. 4-iodo-SAHA inhibits proliferation of SK-BR-3 breast-derived and HT29 colon-derived cell lines with EC50 values comparable to that of SAHA (1.1 and 0.95 μM versus 2.1 and 2 μM, respectively). It is 10-fold more potent as an inhibitor of U937 leukemia cell proliferation compared to SAHA (0.12 μM versus 1.2 μM, respectively).{18112}  

     

    Brand:
    Cayman
    SKU:10495 - 50 mg

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  • 4-iodo-SAHA is a hydrophobic derivative of the class I and class II histone deacetylase (HDAC) inhibitor SAHA. At 1 μM it demonstrates >60% inhibition of HDAC1 and HDAC6 activity in a deacetylase activity assay, similar to that of SAHA. 4-iodo-SAHA inhibits proliferation of SK-BR-3 breast-derived and HT29 colon-derived cell lines with EC50 values comparable to that of SAHA (1.1 and 0.95 μM versus 2.1 and 2 μM, respectively). It is 10-fold more potent as an inhibitor of U937 leukemia cell proliferation compared to SAHA (0.12 μM versus 1.2 μM, respectively).{18112}  

     

    Brand:
    Cayman
    SKU:10495 - 500 mg

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  • Some halogenated amphetamines deplete brain serotonin levels and display pronounced neurotoxicity.{25537} 4-Iodoamphetamine is a halogenated amphetamine featuring an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake by rat brain synaptosomes while showing reduced neurotoxic properties.{20299,20234} This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:9001853 - 1 mg

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  • Some halogenated amphetamines deplete brain serotonin levels and display pronounced neurotoxicity.{25537} 4-Iodoamphetamine is a halogenated amphetamine featuring an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake by rat brain synaptosomes while showing reduced neurotoxic properties.{20299,20234} This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:9001853 - 10 mg

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  • Some halogenated amphetamines deplete brain serotonin levels and display pronounced neurotoxicity.{25537} 4-Iodoamphetamine is a halogenated amphetamine featuring an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake by rat brain synaptosomes while showing reduced neurotoxic properties.{20299,20234} This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:9001853 - 5 mg

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  • 4-IPP is an inhibitor of macrophage migration inhibitory factor (MIF).{59363} It acts as a suicide substrate for MIF, leading to covalent modification of the N-terminal proline required for activation of its catalytic activity. 4-IPP (10 and 100 µM) inhibits the migration and anchorage-independent growth of A549 non-small cell lung cancer (NSCLC) cells. It inhibits proliferation of, and induces apoptosis in, TPC-1 thyroid carcinoma cells when used at concentrations of 50 and 100 µM.{59364} 4-IPP (~50 mg/kg) also inhibits the tautomerase activity of MIF in mouse liver in vivo.{59363}  

     

    Brand:
    Cayman
    SKU:31770 - 10 mg

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  • 4-IPP is an inhibitor of macrophage migration inhibitory factor (MIF).{59363} It acts as a suicide substrate for MIF, leading to covalent modification of the N-terminal proline required for activation of its catalytic activity. 4-IPP (10 and 100 µM) inhibits the migration and anchorage-independent growth of A549 non-small cell lung cancer (NSCLC) cells. It inhibits proliferation of, and induces apoptosis in, TPC-1 thyroid carcinoma cells when used at concentrations of 50 and 100 µM.{59364} 4-IPP (~50 mg/kg) also inhibits the tautomerase activity of MIF in mouse liver in vivo.{59363}  

     

    Brand:
    Cayman
    SKU:31770 - 25 mg

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  • 4-IPP is an inhibitor of macrophage migration inhibitory factor (MIF).{59363} It acts as a suicide substrate for MIF, leading to covalent modification of the N-terminal proline required for activation of its catalytic activity. 4-IPP (10 and 100 µM) inhibits the migration and anchorage-independent growth of A549 non-small cell lung cancer (NSCLC) cells. It inhibits proliferation of, and induces apoptosis in, TPC-1 thyroid carcinoma cells when used at concentrations of 50 and 100 µM.{59364} 4-IPP (~50 mg/kg) also inhibits the tautomerase activity of MIF in mouse liver in vivo.{59363}  

     

    Brand:
    Cayman
    SKU:31770 - 5 mg

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  • 4-IPP is an inhibitor of macrophage migration inhibitory factor (MIF).{59363} It acts as a suicide substrate for MIF, leading to covalent modification of the N-terminal proline required for activation of its catalytic activity. 4-IPP (10 and 100 µM) inhibits the migration and anchorage-independent growth of A549 non-small cell lung cancer (NSCLC) cells. It inhibits proliferation of, and induces apoptosis in, TPC-1 thyroid carcinoma cells when used at concentrations of 50 and 100 µM.{59364} 4-IPP (~50 mg/kg) also inhibits the tautomerase activity of MIF in mouse liver in vivo.{59363}  

     

    Brand:
    Cayman
    SKU:31770 - 50 mg

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  • 4-isocyanato TEMPO is a spin labeling reagent used to label the 2’-position in RNA.{39230} It has been used to study HIV-1 transactivation response RNA and hammerhead ribosome dynamics by electron paramagnetic resonance (EPR) spectroscopy.{39231, 39232}  

     

    Brand:
    Cayman
    SKU:23075 - 1 mg

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  • 4-isocyanato TEMPO is a spin labeling reagent used to label the 2’-position in RNA.{39230} It has been used to study HIV-1 transactivation response RNA and hammerhead ribosome dynamics by electron paramagnetic resonance (EPR) spectroscopy.{39231, 39232}  

     

    Brand:
    Cayman
    SKU:23075 - 10 mg

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  • 4-isocyanato TEMPO is a spin labeling reagent used to label the 2’-position in RNA.{39230} It has been used to study HIV-1 transactivation response RNA and hammerhead ribosome dynamics by electron paramagnetic resonance (EPR) spectroscopy.{39231, 39232}  

     

    Brand:
    Cayman
    SKU:23075 - 5 mg

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  • 4-isocyanato TEMPO is a spin labeling reagent used to label the 2’-position in RNA.{39230} It has been used to study HIV-1 transactivation response RNA and hammerhead ribosome dynamics by electron paramagnetic resonance (EPR) spectroscopy.{39231, 39232}  

     

    Brand:
    Cayman
    SKU:23075 - 500 µg

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  • 4-methoxy PCE (Item No. 9001356) is an analytical reference standard categorized as an arylcyclohexylamine. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:9001356 - 1 mg

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  • 4-methoxy PCE (Item No. 9001356) is an analytical reference standard categorized as an arylcyclohexylamine. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:9001356 - 5 mg

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  • Phencyclidine (PCP), known more commonly as angel dust, is a psychoactive drug that is regulated as a schedule I compound in the United States.{21020} 4-methoxy PCP is an analog of PCP which has recently been commercially produced as a designer drug.{22306} It preferentially binds the σ-2 receptor (Ki = 143 nM) and less weakly binds the NMDA receptor and serotonin transporter (Kis = 404 and 844 nM, respectively).{22308} The toxicological properties of this compound have not been reported. This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:11136 - 10 mg

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  • Phencyclidine (PCP), known more commonly as angel dust, is a psychoactive drug that is regulated as a schedule I compound in the United States.{21020} 4-methoxy PCP is an analog of PCP which has recently been commercially produced as a designer drug.{22306} It preferentially binds the σ-2 receptor (Ki = 143 nM) and less weakly binds the NMDA receptor and serotonin transporter (Kis = 404 and 844 nM, respectively).{22308} The toxicological properties of this compound have not been reported. This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:11136 - 5 mg

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  • Phencyclidine (PCP), known more commonly as angel dust, is a psychoactive drug that is regulated as a schedule I compound in the United States.{21020} 4-methoxy PCP is an analog of PCP which has recently been commercially produced as a designer drug.{22306} It preferentially binds the σ-2 receptor (Ki = 143 nM) and less weakly binds the NMDA receptor and serotonin transporter (Kis = 404 and 844 nM, respectively).{22308} The toxicological properties of this compound have not been reported. This product is intended for forensic and research purposes.  

     

    Brand:
    Cayman
    SKU:11136 - 50 mg

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  • Methedrone (4-methoxymethcathinone) is a substituted cathinone with psychoactive actions. Its use as a recreational drug and its toxicity have recently been reported.{19508,20369} 4-methyl-N,N-DMC is an analog of methedrone, differing by the presence of a second aminomethyl group. Its biological and toxicological properties have not been evaluated. This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:11666 - 10 mg

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  • Methedrone (4-methoxymethcathinone) is a substituted cathinone with psychoactive actions. Its use as a recreational drug and its toxicity have recently been reported.{19508,20369} 4-methyl-N,N-DMC is an analog of methedrone, differing by the presence of a second aminomethyl group. Its biological and toxicological properties have not been evaluated. This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:11666 - 5 mg

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  • Methedrone (4-methoxymethcathinone) is a substituted cathinone with psychoactive actions. Its use as a recreational drug and its toxicity have recently been reported.{19508,20369} 4-methyl-N,N-DMC is an analog of methedrone, differing by the presence of a second aminomethyl group. Its biological and toxicological properties have not been evaluated. This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:11666 - 50 mg

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  • Pyrrolidinophenones are a family of compounds that feature a pyrrolidinyl group affixed to the narcotic cathinone. Many have been identified as components of designer drugs. 4-methoxy-α-Pyrrolidinopentiophenone (4-MeO-α-PVP) (hydrochloride) shares structural features with the stimulant α-PVP. The mechanism of action is unknown for α-PVP, but is believed to be similar to that of the designer drug MDPV (Item No. 10624), which acts as a norepinephrine-dopamine reuptake inhibitor.{18946,18943} This product is intended to be used for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:-
  • Pyrrolidinophenones are a family of compounds that feature a pyrrolidinyl group affixed to the narcotic cathinone. Many have been identified as components of designer drugs. 4-methoxy-α-Pyrrolidinopentiophenone (4-MeO-α-PVP) (hydrochloride) shares structural features with the stimulant α-PVP. The mechanism of action is unknown for α-PVP, but is believed to be similar to that of the designer drug MDPV (Item No. 10624), which acts as a norepinephrine-dopamine reuptake inhibitor.{18946,18943} This product is intended to be used for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:-
  • Pyrrolidinophenones are a family of compounds that feature a pyrrolidinyl group affixed to the narcotic cathinone. Many have been identified as components of designer drugs. 4-methoxy-α-Pyrrolidinopentiophenone (4-MeO-α-PVP) (hydrochloride) shares structural features with the stimulant α-PVP. The mechanism of action is unknown for α-PVP, but is believed to be similar to that of the designer drug MDPV (Item No. 10624), which acts as a norepinephrine-dopamine reuptake inhibitor.{18946,18943} This product is intended to be used for forensic and research applications.  

     

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    Cayman
    SKU:-
  • 4-methoxy-α-Pyrrolidinopropiophenone (hydrochloride) (Item No. 10394), also known as MOPPP, is an analytical reference standard that is structurally categorized as a cathinone. It is a designer drug that has appeared on the illicit drug market.{19734} Its metabolism in rats has been described.{19734,19874} The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:10394 - 1 mg

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  • 4-methoxy-α-Pyrrolidinopropiophenone (hydrochloride) (Item No. 10394), also known as MOPPP, is an analytical reference standard that is structurally categorized as a cathinone. It is a designer drug that has appeared on the illicit drug market.{19734} Its metabolism in rats has been described.{19734,19874} The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:10394 - 5 mg

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  • 4-Methoxyamphetamine (4-MA), is a serotonergic drug of the amphetamine class.{19874} 4-MA exhibits both structural and pharmacological similarity to 3,4-methylenedioxymethamphetamine and may be a more potent hallucinogen, particularly through its effects on serotonergic transmission and through reversible inhibition of the enzyme MAO-A. 4-Methoxyamphetamine (4-MA), is a serotonergic drug of the amphetamine class.{19874} 4-MA exhibits both structural and pharmacological similarity to 3,4-methylenedioxymethamphetamine and may be a more potent hallucinogen, particularly through its effects on serotonergic transmission and through reversible inhibition of the enzyme MAO-A.{19874,21436,21437,21435} This product is intended for research and forensic applications.  

     

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  • 4-methoxythio Benzamide is a synthetic intermediate useful for pharmaceutical synthesis. Thiobenzamides, including 4-methoxythio benzamide, are potent hepatotoxins in vivo.{18419,18420}  

     

    Brand:
    Cayman
    SKU:10552 - 1 g

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  • 4-methoxythio Benzamide is a synthetic intermediate useful for pharmaceutical synthesis. Thiobenzamides, including 4-methoxythio benzamide, are potent hepatotoxins in vivo.{18419,18420}  

     

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    Cayman
    SKU:10552 - 5 g

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  • 4-methoxythio Benzamide is a synthetic intermediate useful for pharmaceutical synthesis. Thiobenzamides, including 4-methoxythio benzamide, are potent hepatotoxins in vivo.{18419,18420}  

     

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    Cayman
    SKU:10552 - 500 mg

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  • Erlotinib (Item No. 10483) is a tyrosine kinase inhibitor that acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 µM).{18354,18362} It binds to the EGF-activated receptor, with the phenyl group at one end sequestered in a hydrophobic pocket of the kinase domain and the ether linkages at the opposite end projecting into solvent.{24659,24660} 4-methyl Erlotinib is an analog of erlotinib characterized by the addition of a methyl group at the four position of the phenyl group. The biochemical and physiological properties of this compound are not known.  

     

    Brand:
    Cayman
    SKU:9001510 - 1 mg

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  • Erlotinib (Item No. 10483) is a tyrosine kinase inhibitor that acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 µM).{18354,18362} It binds to the EGF-activated receptor, with the phenyl group at one end sequestered in a hydrophobic pocket of the kinase domain and the ether linkages at the opposite end projecting into solvent.{24659,24660} 4-methyl Erlotinib is an analog of erlotinib characterized by the addition of a methyl group at the four position of the phenyl group. The biochemical and physiological properties of this compound are not known.  

     

    Brand:
    Cayman
    SKU:9001510 - 10 mg

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  • Erlotinib (Item No. 10483) is a tyrosine kinase inhibitor that acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 µM).{18354,18362} It binds to the EGF-activated receptor, with the phenyl group at one end sequestered in a hydrophobic pocket of the kinase domain and the ether linkages at the opposite end projecting into solvent.{24659,24660} 4-methyl Erlotinib is an analog of erlotinib characterized by the addition of a methyl group at the four position of the phenyl group. The biochemical and physiological properties of this compound are not known.  

     

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    Cayman
    SKU:9001510 - 5 mg

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  • 4-methyl PCP (hydrochloride) (Item No. 31007) is an analytical reference standard categorized as an arylcyclohexylamine. This product is intended for research and forensic applications.  

     

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    Cayman
    SKU:31007 - 1 mg

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  • 4-methyl PCP (hydrochloride) (Item No. 31007) is an analytical reference standard categorized as an arylcyclohexylamine. This product is intended for research and forensic applications.  

     

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    Cayman
    SKU:31007 - 5 mg

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  • 4-methyl-1-Pentanol is a branched chain primary alcohol found in wine and produced during fermentation.{29972} As a volatile compound it is reported to have a nutty odor. It is also used in cosmetic compounds for its antimicrobial effects.{29971}  

     

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    Cayman
    SKU:-

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  • 4-methyl-1-Pentanol is a branched chain primary alcohol found in wine and produced during fermentation.{29972} As a volatile compound it is reported to have a nutty odor. It is also used in cosmetic compounds for its antimicrobial effects.{29971}  

     

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    Cayman
    SKU:-

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  • 4-methyl-1-Pentanol is a branched chain primary alcohol found in wine and produced during fermentation.{29972} As a volatile compound it is reported to have a nutty odor. It is also used in cosmetic compounds for its antimicrobial effects.{29971}  

     

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    Cayman
    SKU:-

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  • 4-methyl-1-Pentanol is a branched chain primary alcohol found in wine and produced during fermentation.{29972} As a volatile compound it is reported to have a nutty odor. It is also used in cosmetic compounds for its antimicrobial effects.{29971}  

     

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    Cayman
    SKU:-

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  • 4-methyl-2-Oxovalerate is an immediate precursor and metabolite of L-leucine. It is a precursor leading to the synthesis of 2-methylpropyl glucosinolate, via L-leucine, in plants. 4-methyl-2-Oxovalerate is one of several plasma metabolites found to differ significantly between type 2 diabetes and control subjects.{33223}  

     

    Brand:
    Cayman
    SKU:21052 -

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  • 4-methyl-2-Oxovalerate is an immediate precursor and metabolite of L-leucine. It is a precursor leading to the synthesis of 2-methylpropyl glucosinolate, via L-leucine, in plants. 4-methyl-2-Oxovalerate is one of several plasma metabolites found to differ significantly between type 2 diabetes and control subjects.{33223}  

     

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    Cayman
    SKU:21052 -

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  • 4-methyl-2-Oxovalerate is an immediate precursor and metabolite of L-leucine. It is a precursor leading to the synthesis of 2-methylpropyl glucosinolate, via L-leucine, in plants. 4-methyl-2-Oxovalerate is one of several plasma metabolites found to differ significantly between type 2 diabetes and control subjects.{33223}  

     

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    Cayman
    SKU:21052 -

    Out of stock

  • 4-methyl-2-Oxovalerate is an immediate precursor and metabolite of L-leucine. It is a precursor leading to the synthesis of 2-methylpropyl glucosinolate, via L-leucine, in plants. 4-methyl-2-Oxovalerate is one of several plasma metabolites found to differ significantly between type 2 diabetes and control subjects.{33223}  

     

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    Cayman
    SKU:21052 -

    Out of stock

  • 4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one is a fluorescent coumarin derivative.{51048,51047} It displays excitation/emission maxima of 323/445 nm, respectively.{51048}  

     

    Brand:
    Cayman
    SKU:28473 - 1 mg

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  • 4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one is a fluorescent coumarin derivative.{51048,51047} It displays excitation/emission maxima of 323/445 nm, respectively.{51048}  

     

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    Cayman
    SKU:28473 - 10 mg

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  • 4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one is a fluorescent coumarin derivative.{51048,51047} It displays excitation/emission maxima of 323/445 nm, respectively.{51048}  

     

    Brand:
    Cayman
    SKU:28473 - 25 mg

    Available on backorder

  • 4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one is a fluorescent coumarin derivative.{51048,51047} It displays excitation/emission maxima of 323/445 nm, respectively.{51048}  

     

    Brand:
    Cayman
    SKU:28473 - 5 mg

    Available on backorder

  • 4-Methyl-7-(4-nitro-2-(trifluoromethyl)phenoxy)-2H-chromen-2-one is a turn-on fluorescent probe for the detection of hydrogen sulfide (H2S).{51047} It can be excited at 348 nm in DMSO and fluorescence intensity increases in the presence of bisulfide (HS-). 4-Methyl-7-(4-nitro-2-(trifluoromethyl)phenoxy)-2H-chromen-2-one is selective for HS- over cysteine, AcO-, F-, H2PO4-, Cl-, Br-, and I- and is not cytotoxic up to a concentration of 150 µg/ml.  

     

    Brand:
    Cayman
    SKU:28471 - 1 mg

    Available on backorder

  • 4-Methyl-7-(4-nitro-2-(trifluoromethyl)phenoxy)-2H-chromen-2-one is a turn-on fluorescent probe for the detection of hydrogen sulfide (H2S).{51047} It can be excited at 348 nm in DMSO and fluorescence intensity increases in the presence of bisulfide (HS-). 4-Methyl-7-(4-nitro-2-(trifluoromethyl)phenoxy)-2H-chromen-2-one is selective for HS- over cysteine, AcO-, F-, H2PO4-, Cl-, Br-, and I- and is not cytotoxic up to a concentration of 150 µg/ml.  

     

    Brand:
    Cayman
    SKU:28471 - 10 mg

    Available on backorder

  • 4-Methyl-7-(4-nitro-2-(trifluoromethyl)phenoxy)-2H-chromen-2-one is a turn-on fluorescent probe for the detection of hydrogen sulfide (H2S).{51047} It can be excited at 348 nm in DMSO and fluorescence intensity increases in the presence of bisulfide (HS-). 4-Methyl-7-(4-nitro-2-(trifluoromethyl)phenoxy)-2H-chromen-2-one is selective for HS- over cysteine, AcO-, F-, H2PO4-, Cl-, Br-, and I- and is not cytotoxic up to a concentration of 150 µg/ml.  

     

    Brand:
    Cayman
    SKU:28471 - 25 mg

    Available on backorder

  • 4-Methyl-7-(4-nitro-2-(trifluoromethyl)phenoxy)-2H-chromen-2-one is a turn-on fluorescent probe for the detection of hydrogen sulfide (H2S).{51047} It can be excited at 348 nm in DMSO and fluorescence intensity increases in the presence of bisulfide (HS-). 4-Methyl-7-(4-nitro-2-(trifluoromethyl)phenoxy)-2H-chromen-2-one is selective for HS- over cysteine, AcO-, F-, H2PO4-, Cl-, Br-, and I- and is not cytotoxic up to a concentration of 150 µg/ml.  

     

    Brand:
    Cayman
    SKU:28471 - 5 mg

    Available on backorder

  • 4-Methyl-7-(4-nitrophenoxy)-2H-chromen-2-one is a fluorescent coumarin derivative.{51048,51047} It displays excitation/emission maxima of 323/445 nm, respectively.{51048} Unlike the hydrogen sulfide probe 7-(2,4-dinitrophenoxy)-4-methyl-2H-chromen-2-one (Item No. 28472), 4-methyl-7-(4-nitrophenoxy)-2H-chromen-2-one does not undergo an increase in fluoresence intensity in the presence of sulfur-containing molecules.{51048,51047}  

     

    Brand:
    Cayman
    SKU:28474 - 1 mg

    Available on backorder

  • 4-Methyl-7-(4-nitrophenoxy)-2H-chromen-2-one is a fluorescent coumarin derivative.{51048,51047} It displays excitation/emission maxima of 323/445 nm, respectively.{51048} Unlike the hydrogen sulfide probe 7-(2,4-dinitrophenoxy)-4-methyl-2H-chromen-2-one (Item No. 28472), 4-methyl-7-(4-nitrophenoxy)-2H-chromen-2-one does not undergo an increase in fluoresence intensity in the presence of sulfur-containing molecules.{51048,51047}  

     

    Brand:
    Cayman
    SKU:28474 - 10 mg

    Available on backorder

  • 4-Methyl-7-(4-nitrophenoxy)-2H-chromen-2-one is a fluorescent coumarin derivative.{51048,51047} It displays excitation/emission maxima of 323/445 nm, respectively.{51048} Unlike the hydrogen sulfide probe 7-(2,4-dinitrophenoxy)-4-methyl-2H-chromen-2-one (Item No. 28472), 4-methyl-7-(4-nitrophenoxy)-2H-chromen-2-one does not undergo an increase in fluoresence intensity in the presence of sulfur-containing molecules.{51048,51047}  

     

    Brand:
    Cayman
    SKU:28474 - 25 mg

    Available on backorder

  • 4-Methyl-7-(4-nitrophenoxy)-2H-chromen-2-one is a fluorescent coumarin derivative.{51048,51047} It displays excitation/emission maxima of 323/445 nm, respectively.{51048} Unlike the hydrogen sulfide probe 7-(2,4-dinitrophenoxy)-4-methyl-2H-chromen-2-one (Item No. 28472), 4-methyl-7-(4-nitrophenoxy)-2H-chromen-2-one does not undergo an increase in fluoresence intensity in the presence of sulfur-containing molecules.{51048,51047}  

     

    Brand:
    Cayman
    SKU:28474 - 5 mg

    Available on backorder

  • 4-methyl-N,N-Dimethylcathinone (hydrochloride) (Item No. 17393) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • 4-methyl-N,N-Dimethylcathinone (hydrochloride) (Item No. 17393) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • 4-methyl-N,N-Dimethylcathinone (hydrochloride) (Item No. 17393) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • α-Ethyltryptamine (AET), like α-methyltryptamine (Item No. 11135), is a psychedelic drug with schedule 1 status in the United States. Both alter monoamine release and re-uptake in the brain.{20018,19758} 4-methyl-α-Ethyltryptamine is a homolog of AET. Its physiological and toxicological properties remain to be elucidated. This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:-
  • α-Ethyltryptamine (AET), like α-methyltryptamine (Item No. 11135), is a psychedelic drug with schedule 1 status in the United States. Both alter monoamine release and re-uptake in the brain.{20018,19758} 4-methyl-α-Ethyltryptamine is a homolog of AET. Its physiological and toxicological properties remain to be elucidated. This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:-
  • α-Ethyltryptamine (AET), like α-methyltryptamine (Item No. 11135), is a psychedelic drug with schedule 1 status in the United States. Both alter monoamine release and re-uptake in the brain.{20018,19758} 4-methyl-α-Ethyltryptamine is a homolog of AET. Its physiological and toxicological properties remain to be elucidated. This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:-
  • 4-methyl-α-Isopropylaminovalerophenone (hydrochloride) (Item No. 31008) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:31008 - 1 mg

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  • 4-methyl-α-Isopropylaminovalerophenone (hydrochloride) (Item No. 31008) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:31008 - 5 mg

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  • 4-methyl-α-Pyrrolidinobutiophenone (4-methyl PBP) is a synthetic cathinone with psychoactive properties which has recently been identified in party pills and powders.{19193,20009} The metabolism of methyl PBP has been characterized.{19963,20462} The biological and toxicological properties of this compound are unknown. This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:9001190 - 10 mg

    Available on backorder

  • 4-methyl-α-Pyrrolidinobutiophenone (4-methyl PBP) is a synthetic cathinone with psychoactive properties which has recently been identified in party pills and powders.{19193,20009} The metabolism of methyl PBP has been characterized.{19963,20462} The biological and toxicological properties of this compound are unknown. This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:9001190 - 5 mg

    Available on backorder

  • 4-methyl-α-Pyrrolidinobutiophenone (4-methyl PBP) is a synthetic cathinone with psychoactive properties which has recently been identified in party pills and powders.{19193,20009} The metabolism of methyl PBP has been characterized.{19963,20462} The biological and toxicological properties of this compound are unknown. This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:9001190 - 50 mg

    Available on backorder

  • 4-methyl-α-Pyrrolidinoisohexanophenone (hydrochloride) (Item No. 31013) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:31013 - 1 mg

    Available on backorder

  • 4-methyl-α-Pyrrolidinoisohexanophenone (hydrochloride) (Item No. 31013) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:31013 - 5 mg

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  • 4-Methylaminoantipyrine is a major active metabolite of the non-opioid prodrug metamizole (Item No. 15771).{25749} It is formed from metamizole by non-enzymatic hydrolysis in the gastrointestinal tract.{57230} 4-Methylaminoantipyrine (0.1 mM) inhibits production of prostaglandin E2 (PGE2; Item No. 14010) induced by the calcium ionophore A23187 (Item Nos. 11016 | 22030) in isolated mouse peritoneal macrophages.{57231} It increases the paw withdrawal threshold in a rat model of carrageenan-induced hyperalgesia when administered at a dose of 160 µg/paw.{57232} 4-Methylaminoantipyrine (60, 90, and 120 mg/kg) reduces LPS-induced pyrexia in rats.{57233} It is also a potential impurity found in commercial preparations of metamizole.{57234}  

     

    Brand:
    Cayman
    SKU:31612 - 1 mg

    Available on backorder

  • 4-Methylaminoantipyrine is a major active metabolite of the non-opioid prodrug metamizole (Item No. 15771).{25749} It is formed from metamizole by non-enzymatic hydrolysis in the gastrointestinal tract.{57230} 4-Methylaminoantipyrine (0.1 mM) inhibits production of prostaglandin E2 (PGE2; Item No. 14010) induced by the calcium ionophore A23187 (Item Nos. 11016 | 22030) in isolated mouse peritoneal macrophages.{57231} It increases the paw withdrawal threshold in a rat model of carrageenan-induced hyperalgesia when administered at a dose of 160 µg/paw.{57232} 4-Methylaminoantipyrine (60, 90, and 120 mg/kg) reduces LPS-induced pyrexia in rats.{57233} It is also a potential impurity found in commercial preparations of metamizole.{57234}  

     

    Brand:
    Cayman
    SKU:31612 - 10 mg

    Available on backorder

  • 4-Methylaminoantipyrine is a major active metabolite of the non-opioid prodrug metamizole (Item No. 15771).{25749} It is formed from metamizole by non-enzymatic hydrolysis in the gastrointestinal tract.{57230} 4-Methylaminoantipyrine (0.1 mM) inhibits production of prostaglandin E2 (PGE2; Item No. 14010) induced by the calcium ionophore A23187 (Item Nos. 11016 | 22030) in isolated mouse peritoneal macrophages.{57231} It increases the paw withdrawal threshold in a rat model of carrageenan-induced hyperalgesia when administered at a dose of 160 µg/paw.{57232} 4-Methylaminoantipyrine (60, 90, and 120 mg/kg) reduces LPS-induced pyrexia in rats.{57233} It is also a potential impurity found in commercial preparations of metamizole.{57234}  

     

    Brand:
    Cayman
    SKU:31612 - 5 mg

    Available on backorder

  • 4-Methylamphetamine (4-MA) (hydrochloride) (Item No. 14215) is an analytical reference standard categorized as an amphetamine. 4-MA acts on norepinephrine (NE), dopamine (DA), and serotonin (5-HT) transporters to increase extracellular levels of these neurotransmitters. In vitro, the potencies of 4-MA for NE and DA release are similar to those of D-amphetamine with EC50 values of 22.2 and 7.2 nM for NE and 44.1 and 8.0 nM for DA, respectively.{36006} 4-MA is more potent than D-amphetamine at releasing serotonin (EC50s = 53.4 and 1,756 nM, respectively). In rats, 4-MA acts as an agonist at 5-HT1A receptors and induces hypothermia.{36005} It is found as a contaminant in amphetamine, and ingestion has been associated with severe intoxication and fatalities.{36004} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-
  • 4-Methylamphetamine (4-MA) (hydrochloride) (Item No. 14215) is an analytical reference standard categorized as an amphetamine. 4-MA acts on norepinephrine (NE), dopamine (DA), and serotonin (5-HT) transporters to increase extracellular levels of these neurotransmitters. In vitro, the potencies of 4-MA for NE and DA release are similar to those of D-amphetamine with EC50 values of 22.2 and 7.2 nM for NE and 44.1 and 8.0 nM for DA, respectively.{36006} 4-MA is more potent than D-amphetamine at releasing serotonin (EC50s = 53.4 and 1,756 nM, respectively). In rats, 4-MA acts as an agonist at 5-HT1A receptors and induces hypothermia.{36005} It is found as a contaminant in amphetamine, and ingestion has been associated with severe intoxication and fatalities.{36004} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-
  • 4-Methylbenzamide oxime is intended to be used as a building block in drug discovery chemistry.  

     

    Brand:
    Cayman
    SKU:-
  • 4-Methylbenzamide oxime is intended to be used as a building block in drug discovery chemistry.  

     

    Brand:
    Cayman
    SKU:-
  • 4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations that also has estrogenic activities.{20419,20420} It has estrogenic activity in fish and in mammals, binding competitively to estrogen receptors and stimulating transactivation.{20419} In addition to reducing receptor sensitivity to estradiol, 4-MBC directs dose-dependent changes in the expression of estrogen receptor subtypes, progesterone receptor, and androgen receptor.{20419,20420} This results in changes in reproductive organ and brain development in both males and females.{20419,20420} When applied topically, it is absorbed systemically and can be detected in urine.{20421}  

     

    Brand:
    Cayman
    SKU:-
  • 4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations that also has estrogenic activities.{20419,20420} It has estrogenic activity in fish and in mammals, binding competitively to estrogen receptors and stimulating transactivation.{20419} In addition to reducing receptor sensitivity to estradiol, 4-MBC directs dose-dependent changes in the expression of estrogen receptor subtypes, progesterone receptor, and androgen receptor.{20419,20420} This results in changes in reproductive organ and brain development in both males and females.{20419,20420} When applied topically, it is absorbed systemically and can be detected in urine.{20421}  

     

    Brand:
    Cayman
    SKU:-
  • 4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations that also has estrogenic activities.{20419,20420} It has estrogenic activity in fish and in mammals, binding competitively to estrogen receptors and stimulating transactivation.{20419} In addition to reducing receptor sensitivity to estradiol, 4-MBC directs dose-dependent changes in the expression of estrogen receptor subtypes, progesterone receptor, and androgen receptor.{20419,20420} This results in changes in reproductive organ and brain development in both males and females.{20419,20420} When applied topically, it is absorbed systemically and can be detected in urine.{20421}  

     

    Brand:
    Cayman
    SKU:-
  • 4-Methylethcathinone (4-MEC) is a cathinone derivative identified in several designer, recreational drugs that are sold as “legal high” replacements for controlled stimulants such as methamphetamine and 3,4-methylenedioxymethamphetamine.{19500,19914,19498} The hydrochloride formulation of this compound is intended for use as a standard for the forensic analysis of samples that may contain 4-MEC.  

     

    Brand:
    Cayman
    SKU:-
  • 4-Methylhistamine is a histamine H4 receptor agonist (Ki = 50 nM).{36324} It is >100-fold selective for H4 over other histamine receptors. 4-Methylhistamine inhibits CRE-β-galactosidase activity induced by forskolin (Item No. 11018) with an EC50 value of 39.8 nM in SK-N-MC cells transfected with the human H4 receptor. It induces a change in eosinophil shape (EC50 = 0.36 μM) and stimulates migration of murine bone marrow mast cells (EC50 = 12 μM), activities that can be inhibited by the histamine H4 antagonist JNJ-7777120 (Item No. 10011925). Intratracheal administration of 4-methylhistamine (10 μg/animal) reduces airway resistance and inflammation and increases the number of CD4+CD25+FoxP3+ regulatory T cells in a mouse model of allergic asthma.{36323} 4-Methylhistamine also reduces epidermal hyperplasis, hyperkeratosis, and lymphocyte infiltration and increases the number of CD4+CD25+FoxP3+ regulatory T cells in a mouse model of psoriasis induced by imiquimod (Item No. 14956).{36325}  

     

    Brand:
    Cayman
    SKU:23761 - 1 mg

    Available on backorder

  • 4-Methylhistamine is a histamine H4 receptor agonist (Ki = 50 nM).{36324} It is >100-fold selective for H4 over other histamine receptors. 4-Methylhistamine inhibits CRE-β-galactosidase activity induced by forskolin (Item No. 11018) with an EC50 value of 39.8 nM in SK-N-MC cells transfected with the human H4 receptor. It induces a change in eosinophil shape (EC50 = 0.36 μM) and stimulates migration of murine bone marrow mast cells (EC50 = 12 μM), activities that can be inhibited by the histamine H4 antagonist JNJ-7777120 (Item No. 10011925). Intratracheal administration of 4-methylhistamine (10 μg/animal) reduces airway resistance and inflammation and increases the number of CD4+CD25+FoxP3+ regulatory T cells in a mouse model of allergic asthma.{36323} 4-Methylhistamine also reduces epidermal hyperplasis, hyperkeratosis, and lymphocyte infiltration and increases the number of CD4+CD25+FoxP3+ regulatory T cells in a mouse model of psoriasis induced by imiquimod (Item No. 14956).{36325}  

     

    Brand:
    Cayman
    SKU:23761 - 10 mg

    Available on backorder

  • 4-Methylhistamine is a histamine H4 receptor agonist (Ki = 50 nM).{36324} It is >100-fold selective for H4 over other histamine receptors. 4-Methylhistamine inhibits CRE-β-galactosidase activity induced by forskolin (Item No. 11018) with an EC50 value of 39.8 nM in SK-N-MC cells transfected with the human H4 receptor. It induces a change in eosinophil shape (EC50 = 0.36 μM) and stimulates migration of murine bone marrow mast cells (EC50 = 12 μM), activities that can be inhibited by the histamine H4 antagonist JNJ-7777120 (Item No. 10011925). Intratracheal administration of 4-methylhistamine (10 μg/animal) reduces airway resistance and inflammation and increases the number of CD4+CD25+FoxP3+ regulatory T cells in a mouse model of allergic asthma.{36323} 4-Methylhistamine also reduces epidermal hyperplasis, hyperkeratosis, and lymphocyte infiltration and increases the number of CD4+CD25+FoxP3+ regulatory T cells in a mouse model of psoriasis induced by imiquimod (Item No. 14956).{36325}  

     

    Brand:
    Cayman
    SKU:23761 - 5 mg

    Available on backorder

  • Mephedrone (Item No. 10801) is a designer drug of the phenethylamine class with putative stimulant and entactogen-like properties.{19656,19498,19193} 4-Methylmethamphetamine (4-MMA) is a metabolite of mephedrone that lacks the β-keto moiety.{19964} This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:9001345 - 10 mg

    Available on backorder

  • Mephedrone (Item No. 10801) is a designer drug of the phenethylamine class with putative stimulant and entactogen-like properties.{19656,19498,19193} 4-Methylmethamphetamine (4-MMA) is a metabolite of mephedrone that lacks the β-keto moiety.{19964} This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:9001345 - 5 mg

    Available on backorder

  • Mephedrone (Item No. 10801) is a designer drug of the phenethylamine class with putative stimulant and entactogen-like properties.{19656,19498,19193} 4-Methylmethamphetamine (4-MMA) is a metabolite of mephedrone that lacks the β-keto moiety.{19964} This product is intended for forensic and research applications.  

     

    Brand:
    Cayman
    SKU:9001345 - 50 mg

    Available on backorder

  • 4-Methylpentanoic acid-d12 is intended for use as an internal standard for the quantification of 4-methylpentanoic acid by GC- or LC-MS. 4-Methylpentanoic acid is a short-chain volatile fatty acid that is produced during wastewater treatment using anaerobic membrane bioreactors.{46333} It is a synthetic intermediate in the synthesis of biodiesel, polyhydroxyalkanoate (PHA) biopolymers, and various organic compounds.  

     

    Brand:
    Cayman
    SKU:27873 - 100 mg

    Available on backorder

  • 4-Methylpentanoic acid-d12 is intended for use as an internal standard for the quantification of 4-methylpentanoic acid by GC- or LC-MS. 4-Methylpentanoic acid is a short-chain volatile fatty acid that is produced during wastewater treatment using anaerobic membrane bioreactors.{46333} It is a synthetic intermediate in the synthesis of biodiesel, polyhydroxyalkanoate (PHA) biopolymers, and various organic compounds.  

     

    Brand:
    Cayman
    SKU:27873 - 250 mg

    Available on backorder

  • 4-Methylpentanoic acid-d12 is intended for use as an internal standard for the quantification of 4-methylpentanoic acid by GC- or LC-MS. 4-Methylpentanoic acid is a short-chain volatile fatty acid that is produced during wastewater treatment using anaerobic membrane bioreactors.{46333} It is a synthetic intermediate in the synthesis of biodiesel, polyhydroxyalkanoate (PHA) biopolymers, and various organic compounds.  

     

    Brand:
    Cayman
    SKU:27873 - 50 mg

    Available on backorder

  • 4-Methylpentanoic acid-d12 is intended for use as an internal standard for the quantification of 4-methylpentanoic acid by GC- or LC-MS. 4-Methylpentanoic acid is a short-chain volatile fatty acid that is produced during wastewater treatment using anaerobic membrane bioreactors.{46333} It is a synthetic intermediate in the synthesis of biodiesel, polyhydroxyalkanoate (PHA) biopolymers, and various organic compounds.  

     

    Brand:
    Cayman
    SKU:27873 - 500 mg

    Available on backorder

  • 4-Methylumbelliferone (4-ΜU) is a synthetic coumarin with diverse biological activities.{52251,52252,27251} It inhibits hyaluronic acid synthesis in PC3-ML and DU145 cells (IC50s = ~0.4 mM for both).{52251} 4-MU inhibits the growth of PC3-ML, DU145, C4-2B, LNCaP, and LAPC-4 prostate cancer cells (IC50s = 0.2-0.4 mM) and invasion and chemotactic motility of PC3-ML and DU145 cells in vitro. It reduces tumor growth and microvessel density in a PC3-ML mouse xenograft model when administered at doses of 225 and 450 mg/kg twice per day. 4-ΜU is active against H. pylori and V. cholerae in vitro (MICs = 59 and 100-200 μg/ml, respectively).{52252} Derivatives and conjugates of 4-ΜU have been used as fluorogenic substrates to measure enzyme activity.{39610,26284,47304} Upon enzymatic cleavage, 4-ΜU is released and its fluorescence can be used to quantify enzyme activity. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251}  

     

    Brand:
    Cayman
    SKU:29603 - 100 g

    Available on backorder

  • 4-Methylumbelliferone (4-ΜU) is a synthetic coumarin with diverse biological activities.{52251,52252,27251} It inhibits hyaluronic acid synthesis in PC3-ML and DU145 cells (IC50s = ~0.4 mM for both).{52251} 4-MU inhibits the growth of PC3-ML, DU145, C4-2B, LNCaP, and LAPC-4 prostate cancer cells (IC50s = 0.2-0.4 mM) and invasion and chemotactic motility of PC3-ML and DU145 cells in vitro. It reduces tumor growth and microvessel density in a PC3-ML mouse xenograft model when administered at doses of 225 and 450 mg/kg twice per day. 4-ΜU is active against H. pylori and V. cholerae in vitro (MICs = 59 and 100-200 μg/ml, respectively).{52252} Derivatives and conjugates of 4-ΜU have been used as fluorogenic substrates to measure enzyme activity.{39610,26284,47304} Upon enzymatic cleavage, 4-ΜU is released and its fluorescence can be used to quantify enzyme activity. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251}  

     

    Brand:
    Cayman
    SKU:29603 - 250 g

    Available on backorder

  • 4-Methylumbelliferone (4-ΜU) is a synthetic coumarin with diverse biological activities.{52251,52252,27251} It inhibits hyaluronic acid synthesis in PC3-ML and DU145 cells (IC50s = ~0.4 mM for both).{52251} 4-MU inhibits the growth of PC3-ML, DU145, C4-2B, LNCaP, and LAPC-4 prostate cancer cells (IC50s = 0.2-0.4 mM) and invasion and chemotactic motility of PC3-ML and DU145 cells in vitro. It reduces tumor growth and microvessel density in a PC3-ML mouse xenograft model when administered at doses of 225 and 450 mg/kg twice per day. 4-ΜU is active against H. pylori and V. cholerae in vitro (MICs = 59 and 100-200 μg/ml, respectively).{52252} Derivatives and conjugates of 4-ΜU have been used as fluorogenic substrates to measure enzyme activity.{39610,26284,47304} Upon enzymatic cleavage, 4-ΜU is released and its fluorescence can be used to quantify enzyme activity. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251}  

     

    Brand:
    Cayman
    SKU:29603 - 50 g

    Available on backorder

  • 4-Methylumbelliferone (4-ΜU) is a synthetic coumarin with diverse biological activities.{52251,52252,27251} It inhibits hyaluronic acid synthesis in PC3-ML and DU145 cells (IC50s = ~0.4 mM for both).{52251} 4-MU inhibits the growth of PC3-ML, DU145, C4-2B, LNCaP, and LAPC-4 prostate cancer cells (IC50s = 0.2-0.4 mM) and invasion and chemotactic motility of PC3-ML and DU145 cells in vitro. It reduces tumor growth and microvessel density in a PC3-ML mouse xenograft model when administered at doses of 225 and 450 mg/kg twice per day. 4-ΜU is active against H. pylori and V. cholerae in vitro (MICs = 59 and 100-200 μg/ml, respectively).{52252} Derivatives and conjugates of 4-ΜU have been used as fluorogenic substrates to measure enzyme activity.{39610,26284,47304} Upon enzymatic cleavage, 4-ΜU is released and its fluorescence can be used to quantify enzyme activity. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251}  

     

    Brand:
    Cayman
    SKU:29603 - 500 g

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  • 4-Methylumbelliferyl 2-acetoamido-2-deoxy-α-D-galactopyranoside (4-MU-2-acetoamido-2-deoxy-α-Gal) is a fluorogenic substrate used to quantify α- and β-galactopyranosaminidase activity.{41895} 4-MU-2-acetoamido-2-deoxy-α-Gal is cleaved by α- and β-galactopyranosaminidase to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251}  

     

    Brand:
    Cayman
    SKU:23099 - 1 mg

    Available on backorder

  • 4-Methylumbelliferyl 2-acetoamido-2-deoxy-α-D-galactopyranoside (4-MU-2-acetoamido-2-deoxy-α-Gal) is a fluorogenic substrate used to quantify α- and β-galactopyranosaminidase activity.{41895} 4-MU-2-acetoamido-2-deoxy-α-Gal is cleaved by α- and β-galactopyranosaminidase to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251}  

     

    Brand:
    Cayman
    SKU:23099 - 10 mg

    Available on backorder

  • 4-Methylumbelliferyl 2-acetoamido-2-deoxy-α-D-galactopyranoside (4-MU-2-acetoamido-2-deoxy-α-Gal) is a fluorogenic substrate used to quantify α- and β-galactopyranosaminidase activity.{41895} 4-MU-2-acetoamido-2-deoxy-α-Gal is cleaved by α- and β-galactopyranosaminidase to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251}  

     

    Brand:
    Cayman
    SKU:23099 - 25 mg

    Available on backorder

  • 4-Methylumbelliferyl 2-acetoamido-2-deoxy-α-D-galactopyranoside (4-MU-2-acetoamido-2-deoxy-α-Gal) is a fluorogenic substrate used to quantify α- and β-galactopyranosaminidase activity.{41895} 4-MU-2-acetoamido-2-deoxy-α-Gal is cleaved by α- and β-galactopyranosaminidase to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251}  

     

    Brand:
    Cayman
    SKU:23099 - 5 mg

    Available on backorder

  • 4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (4-MU-α-GlcNS) is a fluorogenic substrate of heparin sulphamidase.{39610} Heparin sulphamidase cleaves 4-MU-α-GlcNS to yield 4-MU-α-GlcNH2, which is then cleaved by α-glucosaminidase to release the fluorescent product 4-MU, which displays an emission maxima of 445-454 nm.{39610,27251} The excitation maxima for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.{27251} 4-MU-α-GlcNS has been used to quantify heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders.{39611}  

     

    Brand:
    Cayman
    SKU:24931 - 1 mg

    Available on backorder

  • 4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (4-MU-α-GlcNS) is a fluorogenic substrate of heparin sulphamidase.{39610} Heparin sulphamidase cleaves 4-MU-α-GlcNS to yield 4-MU-α-GlcNH2, which is then cleaved by α-glucosaminidase to release the fluorescent product 4-MU, which displays an emission maxima of 445-454 nm.{39610,27251} The excitation maxima for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.{27251} 4-MU-α-GlcNS has been used to quantify heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders.{39611}  

     

    Brand:
    Cayman
    SKU:24931 - 500 µg

    Available on backorder

  • 4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is a fluorogenic substrate of palmitoyl-protein thioesterase (PPT, also known as CLN1), a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. 4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is cleaved by PPT/CLN1 to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251} This substrate is used in assays that measure PPT activity, which is commonly deficient in the neurodegenerative disorder known as infantile neuronal ceroid lipofuscinosis.{31634,31635}  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • 4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is a fluorogenic substrate of palmitoyl-protein thioesterase (PPT, also known as CLN1), a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. 4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is cleaved by PPT/CLN1 to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251} This substrate is used in assays that measure PPT activity, which is commonly deficient in the neurodegenerative disorder known as infantile neuronal ceroid lipofuscinosis.{31634,31635}  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • 4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is a fluorogenic substrate of palmitoyl-protein thioesterase (PPT, also known as CLN1), a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. 4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is cleaved by PPT/CLN1 to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251} This substrate is used in assays that measure PPT activity, which is commonly deficient in the neurodegenerative disorder known as infantile neuronal ceroid lipofuscinosis.{31634,31635}  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • 4-Methylumbelliferyl caprylate (MUCAP) is a fluorogenic substrate for C8 esterase.{42625} MUCAP is cleaved by C8 esterase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251}  

     

    Brand:
    Cayman
    SKU:26802 - 1 g

    Available on backorder

  • 4-Methylumbelliferyl caprylate (MUCAP) is a fluorogenic substrate for C8 esterase.{42625} MUCAP is cleaved by C8 esterase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251}  

     

    Brand:
    Cayman
    SKU:26802 - 10 g

    Available on backorder

  • 4-Methylumbelliferyl caprylate (MUCAP) is a fluorogenic substrate for C8 esterase.{42625} MUCAP is cleaved by C8 esterase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251}  

     

    Brand:
    Cayman
    SKU:26802 - 25 g

    Available on backorder

  • 4-Methylumbelliferyl caprylate (MUCAP) is a fluorogenic substrate for C8 esterase.{42625} MUCAP is cleaved by C8 esterase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251}  

     

    Brand:
    Cayman
    SKU:26802 - 5 g

    Available on backorder

  • 4-Methylumbelliferyl (4-MU) oleate is a fluorogenic substrate for acid and alkaline lipases.{31463,31464,31465} It is cleaved by lipases, liberating 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.{27251}  

     

    Brand:
    Cayman
    SKU:19590 -

    Available on backorder

  • 4-Methylumbelliferyl (4-MU) oleate is a fluorogenic substrate for acid and alkaline lipases.{31463,31464,31465} It is cleaved by lipases, liberating 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.{27251}  

     

    Brand:
    Cayman
    SKU:19590 -

    Available on backorder

  • 4-Methylumbelliferyl (4-MU) oleate is a fluorogenic substrate for acid and alkaline lipases.{31463,31464,31465} It is cleaved by lipases, liberating 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.{27251}  

     

    Brand:
    Cayman
    SKU:19590 -

    Available on backorder

  • 4-Methylumbelliferyl (4-MU) oleate is a fluorogenic substrate for acid and alkaline lipases.{31463,31464,31465} It is cleaved by lipases, liberating 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.{27251}  

     

    Brand:
    Cayman
    SKU:19590 -

    Available on backorder

  • Cholesterol ester storage disease and Wolman disease are recessive autosomal disorders caused by a deficiency in lysosomal acid lipase (LAL), also known as cholesteryl ester hydrolase.{26282,26283} 4-Methylumbelliferyl palmitate (4-MUP) is a fluorogenic substrate for lysosomal acid lypase (LAL).{26284} 4-MUP is cleaved by LAL to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251} 4-MUP may also be cleaved by other acid lipases.{26285,26286} Recent advances allow the assessment of LAL activity in very small blood volumes using 4-MUP.{26282,26283}  

     

    Brand:
    Cayman
    SKU:-
  • Cholesterol ester storage disease and Wolman disease are recessive autosomal disorders caused by a deficiency in lysosomal acid lipase (LAL), also known as cholesteryl ester hydrolase.{26282,26283} 4-Methylumbelliferyl palmitate (4-MUP) is a fluorogenic substrate for lysosomal acid lypase (LAL).{26284} 4-MUP is cleaved by LAL to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251} 4-MUP may also be cleaved by other acid lipases.{26285,26286} Recent advances allow the assessment of LAL activity in very small blood volumes using 4-MUP.{26282,26283}  

     

    Brand:
    Cayman
    SKU:-
  • Cholesterol ester storage disease and Wolman disease are recessive autosomal disorders caused by a deficiency in lysosomal acid lipase (LAL), also known as cholesteryl ester hydrolase.{26282,26283} 4-Methylumbelliferyl palmitate (4-MUP) is a fluorogenic substrate for lysosomal acid lypase (LAL).{26284} 4-MUP is cleaved by LAL to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251} 4-MUP may also be cleaved by other acid lipases.{26285,26286} Recent advances allow the assessment of LAL activity in very small blood volumes using 4-MUP.{26282,26283}  

     

    Brand:
    Cayman
    SKU:-
  • Cholesterol ester storage disease and Wolman disease are recessive autosomal disorders caused by a deficiency in lysosomal acid lipase (LAL), also known as cholesteryl ester hydrolase.{26282,26283} 4-Methylumbelliferyl palmitate (4-MUP) is a fluorogenic substrate for lysosomal acid lypase (LAL).{26284} 4-MUP is cleaved by LAL to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251} 4-MUP may also be cleaved by other acid lipases.{26285,26286} Recent advances allow the assessment of LAL activity in very small blood volumes using 4-MUP.{26282,26283}  

     

    Brand:
    Cayman
    SKU:-
  • 4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity.{41061} 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251} It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient.{41061} 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.{41060}  

     

    Brand:
    Cayman
    SKU:20907 -

    Out of stock

  • 4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity.{41061} 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251} It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient.{41061} 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.{41060}  

     

    Brand:
    Cayman
    SKU:20907 -

    Out of stock

  • 4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity.{41061} 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251} It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient.{41061} 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.{41060}  

     

    Brand:
    Cayman
    SKU:20907 -

    Out of stock

  • 4-Methylumbelliferyl β-D-N,N’-diacetylchitobioside (4-ΜU-(GlcNAc)2) is a fluorogenic substrate for chitinases and chitobiosidases.{45280,45281} 4-ΜU-(GlcNAc)2 is cleaved by chitinases and chitobiosidases to release the fluorescent moiety 4-ΜU. 4-ΜU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.  

     

    Brand:
    Cayman
    SKU:27730 - 1 mg

    Available on backorder

  • 4-Methylumbelliferyl β-D-N,N’-diacetylchitobioside (4-ΜU-(GlcNAc)2) is a fluorogenic substrate for chitinases and chitobiosidases.{45280,45281} 4-ΜU-(GlcNAc)2 is cleaved by chitinases and chitobiosidases to release the fluorescent moiety 4-ΜU. 4-ΜU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.  

     

    Brand:
    Cayman
    SKU:27730 - 10 mg

    Available on backorder

  • 4-Methylumbelliferyl β-D-N,N’-diacetylchitobioside (4-ΜU-(GlcNAc)2) is a fluorogenic substrate for chitinases and chitobiosidases.{45280,45281} 4-ΜU-(GlcNAc)2 is cleaved by chitinases and chitobiosidases to release the fluorescent moiety 4-ΜU. 4-ΜU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.  

     

    Brand:
    Cayman
    SKU:27730 - 5 mg

    Available on backorder

  • 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside is a fluorogenic substrate for β-hexosaminidases.{47303,47304} Upon enzymatic cleavage by β-hexosaminidases, 4-methylumbelliferone (4-ΜU) is released and its fluorescence can be used to quantify β-hexosaminidase activity. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251} 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside has been used to quantify β-hexosaminidase activity in serum or leukocytes from patients with GM2 gangliosidoses such as Tay-Sachs disease, which is characterized by defects in the α subunit of β-hexosaminidase.{47304,40891}  

     

    Brand:
    Cayman
    SKU:26953 - 1 g

    Available on backorder

  • 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside is a fluorogenic substrate for β-hexosaminidases.{47303,47304} Upon enzymatic cleavage by β-hexosaminidases, 4-methylumbelliferone (4-ΜU) is released and its fluorescence can be used to quantify β-hexosaminidase activity. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251} 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside has been used to quantify β-hexosaminidase activity in serum or leukocytes from patients with GM2 gangliosidoses such as Tay-Sachs disease, which is characterized by defects in the α subunit of β-hexosaminidase.{47304,40891}  

     

    Brand:
    Cayman
    SKU:26953 - 100 mg

    Available on backorder

  • 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside is a fluorogenic substrate for β-hexosaminidases.{47303,47304} Upon enzymatic cleavage by β-hexosaminidases, 4-methylumbelliferone (4-ΜU) is released and its fluorescence can be used to quantify β-hexosaminidase activity. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251} 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside has been used to quantify β-hexosaminidase activity in serum or leukocytes from patients with GM2 gangliosidoses such as Tay-Sachs disease, which is characterized by defects in the α subunit of β-hexosaminidase.{47304,40891}  

     

    Brand:
    Cayman
    SKU:26953 - 250 mg

    Available on backorder

  • 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside is a fluorogenic substrate for β-hexosaminidases.{47303,47304} Upon enzymatic cleavage by β-hexosaminidases, 4-methylumbelliferone (4-ΜU) is released and its fluorescence can be used to quantify β-hexosaminidase activity. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251} 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside has been used to quantify β-hexosaminidase activity in serum or leukocytes from patients with GM2 gangliosidoses such as Tay-Sachs disease, which is characterized by defects in the α subunit of β-hexosaminidase.{47304,40891}  

     

    Brand:
    Cayman
    SKU:26953 - 500 mg

    Available on backorder

  • 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is a fluorogenic substrate of neuraminidases.{27249} 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is cleaved by neuraminidases to release the fluorescence moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid has been used to quantify neuraminidase activity in mammalian cells and clinical isolates of influenza virus.{27250,27253,27252}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is a fluorogenic substrate of neuraminidases.{27249} 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is cleaved by neuraminidases to release the fluorescence moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid has been used to quantify neuraminidase activity in mammalian cells and clinical isolates of influenza virus.{27250,27253,27252}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is a fluorogenic substrate of neuraminidases.{27249} 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is cleaved by neuraminidases to release the fluorescence moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid has been used to quantify neuraminidase activity in mammalian cells and clinical isolates of influenza virus.{27250,27253,27252}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is a fluorogenic substrate of neuraminidases.{27249} 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid is cleaved by neuraminidases to release the fluorescence moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid has been used to quantify neuraminidase activity in mammalian cells and clinical isolates of influenza virus.{27250,27253,27252}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 4-Methylumbelliferyl-α-D-galactopyranoside (4-MU-α-Gal) is a fluorogenic substrate of α-galactosidase.{33136,33137} In addition to its use in characterizing novel α-galactosidases, 4-MU-α-Gal is used in assays to evaluate deficiency in α-galactosidase activity related to Fabry disease.{33138} Hydrolysis of 4-MU-α-Gal releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.{27251}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 4-Methylumbelliferyl-α-D-galactopyranoside (4-MU-α-Gal) is a fluorogenic substrate of α-galactosidase.{33136,33137} In addition to its use in characterizing novel α-galactosidases, 4-MU-α-Gal is used in assays to evaluate deficiency in α-galactosidase activity related to Fabry disease.{33138} Hydrolysis of 4-MU-α-Gal releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.{27251}  

     

    Brand:
    Cayman
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  • 4-Methylumbelliferyl-α-D-galactopyranoside (4-MU-α-Gal) is a fluorogenic substrate of α-galactosidase.{33136,33137} In addition to its use in characterizing novel α-galactosidases, 4-MU-α-Gal is used in assays to evaluate deficiency in α-galactosidase activity related to Fabry disease.{33138} Hydrolysis of 4-MU-α-Gal releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.{27251}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 4-Methylumbelliferyl-α-D-galactopyranoside (4-MU-α-Gal) is a fluorogenic substrate of α-galactosidase.{33136,33137} In addition to its use in characterizing novel α-galactosidases, 4-MU-α-Gal is used in assays to evaluate deficiency in α-galactosidase activity related to Fabry disease.{33138} Hydrolysis of 4-MU-α-Gal releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.{27251}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 4-Methylumbelliferyl-α-D-glucopyranoside is a fluorogenic substrate for α-glucosidase.{49104,49103} 4-Methylumbelliferyl-α-D-glucopyranoside is cleaved by α-glucosidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251} 4-Methylumbelliferyl-α-D-glucopyranoside has been used to quantify α-glucosidase activity in infant blood spot samples as a biomarker of Fabry and Pompe diseases, lysosomal storage disorders characterized by a deficiency in the enzyme.{49104,49103}  

     

    Brand:
    Cayman
    SKU:26810 - 100 mg

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  • 4-Methylumbelliferyl-α-D-glucopyranoside is a fluorogenic substrate for α-glucosidase.{49104,49103} 4-Methylumbelliferyl-α-D-glucopyranoside is cleaved by α-glucosidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251} 4-Methylumbelliferyl-α-D-glucopyranoside has been used to quantify α-glucosidase activity in infant blood spot samples as a biomarker of Fabry and Pompe diseases, lysosomal storage disorders characterized by a deficiency in the enzyme.{49104,49103}  

     

    Brand:
    Cayman
    SKU:26810 - 25 mg

    Available on backorder

  • 4-Methylumbelliferyl-α-D-glucopyranoside is a fluorogenic substrate for α-glucosidase.{49104,49103} 4-Methylumbelliferyl-α-D-glucopyranoside is cleaved by α-glucosidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases.{27251} 4-Methylumbelliferyl-α-D-glucopyranoside has been used to quantify α-glucosidase activity in infant blood spot samples as a biomarker of Fabry and Pompe diseases, lysosomal storage disorders characterized by a deficiency in the enzyme.{49104,49103}  

     

    Brand:
    Cayman
    SKU:26810 - 50 mg

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  • 4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and heparin sulfate. 4-Methylumbelliferyl-α-L-iduronide is cleaved by α-L-iduronidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251} This substrate is used in assays that measure the activity of α-L-iduronidase, which is commonly deficient in a type of lysosomal storage disease called mucopolysaccharidosis.{31700}  

     

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    Cayman
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  • 4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and heparin sulfate. 4-Methylumbelliferyl-α-L-iduronide is cleaved by α-L-iduronidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251} This substrate is used in assays that measure the activity of α-L-iduronidase, which is commonly deficient in a type of lysosomal storage disease called mucopolysaccharidosis.{31700}  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • 4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and heparin sulfate. 4-Methylumbelliferyl-α-L-iduronide is cleaved by α-L-iduronidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251} This substrate is used in assays that measure the activity of α-L-iduronidase, which is commonly deficient in a type of lysosomal storage disease called mucopolysaccharidosis.{31700}  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder