Cayman
Showing 5851–6000 of 45550 results
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4-epi Minocycline is the main degradation product of and a potential impurity in commercial preparations of minocycline.{37048,37047} Minocycline (Item No. 14454) is a broad spectrum tetracycline antibiotic that has a particularly long half-life in serum. Formulations containing minocycline have been used in the treatment of acne in older patients.{22890} Minocycline also has both anti-inflammatory and neuroprotective actions.{22888,22889}
Brand:CaymanSKU:90001066 - 500 µgAvailable on backorder
Chlortetracycline is an analog of tetracycline (Item No. 14328), a broad spectrum antibiotic. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects of the innate immune response.{27378,27379,27377,17512} 4-epi-Chlortetracycline is an epimer of chlortetracycline.
Brand:CaymanSKU:-Out of stock
Chlortetracycline is an analog of tetracycline (Item No. 14328), a broad spectrum antibiotic. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects of the innate immune response.{27378,27379,27377,17512} 4-epi-Chlortetracycline is an epimer of chlortetracycline.
Brand:CaymanSKU:-Out of stock
Chlortetracycline is an analog of tetracycline (Item No. 14328), a broad spectrum antibiotic. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects of the innate immune response.{27378,27379,27377,17512} 4-epi-Chlortetracycline is an epimer of chlortetracycline.
Brand:CaymanSKU:-Out of stock
4-Epianhydrochlortetracycline is a derivative of tetracycline (Item No. 14328).{41116} It inhibits matrix metalloproteinase-9 (MMP-9) activity in a dose-dependent manner in an assay for collagen degradation. 4-Epianhydrochlortetracycline also completely inhibits neutrophil-derived MMP-9 degradation of denatured collagen at a concentration of 500 μg/ml. Unlike tetracycline, 4-epianhydrochlortetracycline lacks antibiotic activity.
Brand:CaymanSKU:23146 - 1 mgAvailable on backorder
4-Epianhydrochlortetracycline is a derivative of tetracycline (Item No. 14328).{41116} It inhibits matrix metalloproteinase-9 (MMP-9) activity in a dose-dependent manner in an assay for collagen degradation. 4-Epianhydrochlortetracycline also completely inhibits neutrophil-derived MMP-9 degradation of denatured collagen at a concentration of 500 μg/ml. Unlike tetracycline, 4-epianhydrochlortetracycline lacks antibiotic activity.
Brand:CaymanSKU:23146 - 5 mgAvailable on backorder
4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline (Item No. 14422).{41111,41110} Unlike doxycycline, 4-epidoxycycline lacks antibiotic activity, therefore, it may not induce the intestinal inflammation in mice associated with doxycycline use. It is an alternative to doxycycline to inactivate the transactivator protein tTA or activate the reverse transactivator rtTA protein in Tet-Off- and Tet-On-based gene expression systems in vitro and in mice.
Brand:CaymanSKU:23225 - 1 mgAvailable on backorder
4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline (Item No. 14422).{41111,41110} Unlike doxycycline, 4-epidoxycycline lacks antibiotic activity, therefore, it may not induce the intestinal inflammation in mice associated with doxycycline use. It is an alternative to doxycycline to inactivate the transactivator protein tTA or activate the reverse transactivator rtTA protein in Tet-Off- and Tet-On-based gene expression systems in vitro and in mice.
Brand:CaymanSKU:23225 - 500 µgAvailable on backorder
Substituted cathinones, including 4-methylmethcathinone (hydrochloride) (Item No. 10801) and 4-methylethcathinone (hydrochloride) (Item No. 9001069) are psychoactive compounds commonly used as recreational drugs.{19500,19508} 4-Ethylethcathinone is a substituted cathinone with potential for abuse. Its physiological and toxicological properties have not been characterized. This product is intended for forensic applications.
Brand:CaymanSKU:11197 - 10 mgAvailable on backorder
Substituted cathinones, including 4-methylmethcathinone (hydrochloride) (Item No. 10801) and 4-methylethcathinone (hydrochloride) (Item No. 9001069) are psychoactive compounds commonly used as recreational drugs.{19500,19508} 4-Ethylethcathinone is a substituted cathinone with potential for abuse. Its physiological and toxicological properties have not been characterized. This product is intended for forensic applications.
Brand:CaymanSKU:11197 - 5 mgAvailable on backorder
Substituted cathinones, including 4-methylmethcathinone (hydrochloride) (Item No. 10801) and 4-methylethcathinone (hydrochloride) (Item No. 9001069) are psychoactive compounds commonly used as recreational drugs.{19500,19508} 4-Ethylethcathinone is a substituted cathinone with potential for abuse. Its physiological and toxicological properties have not been characterized. This product is intended for forensic applications.
Brand:CaymanSKU:11197 - 50 mgAvailable on backorder
4-fluoro ABUTINACA (Item No. 30724) is an analytical reference standard that is structurally similar to known synthetic cannabinoids. This product is intended for research and forensic applications.
Brand:CaymanSKU:30724 - 1 mgAvailable on backorder
4-fluoro ABUTINACA (Item No. 30724) is an analytical reference standard that is structurally similar to known synthetic cannabinoids. This product is intended for research and forensic applications.
Brand:CaymanSKU:30724 - 5 mgAvailable on backorder
Benzylpiperazines (BZP) are stimulant drugs which inhibit monoamine uptake.{20498,20500} BZP and substituted derivatives, such as 1-(3,4-methylenedioxybenzyl)piperazine, have been identified as designer drugs or drugs of abuse.{19508,20497} 4-fluoro BZP is a substituted BZP with a potential for abuse. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications. 4-fluoro BZP is also used as a precursor in the synthesis of certain bioactive compounds.{20501}
Brand:CaymanSKU:11112 - 10 mgAvailable on backorder
Benzylpiperazines (BZP) are stimulant drugs which inhibit monoamine uptake.{20498,20500} BZP and substituted derivatives, such as 1-(3,4-methylenedioxybenzyl)piperazine, have been identified as designer drugs or drugs of abuse.{19508,20497} 4-fluoro BZP is a substituted BZP with a potential for abuse. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications. 4-fluoro BZP is also used as a precursor in the synthesis of certain bioactive compounds.{20501}
Brand:CaymanSKU:11112 - 100 mgAvailable on backorder
Benzylpiperazines (BZP) are stimulant drugs which inhibit monoamine uptake.{20498,20500} BZP and substituted derivatives, such as 1-(3,4-methylenedioxybenzyl)piperazine, have been identified as designer drugs or drugs of abuse.{19508,20497} 4-fluoro BZP is a substituted BZP with a potential for abuse. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications. 4-fluoro BZP is also used as a precursor in the synthesis of certain bioactive compounds.{20501}
Brand:CaymanSKU:11112 - 50 mgAvailable on backorder
4-fluoro MDMB-BUTINACA 3-carboxyindazole metabolite (Item No. 27819) is an analytical reference standard that is structurally similar to known synthetic cannabinoid metabolites. 4-fluoro MDMB-BUTINACA 3-carboxyindazole metabolite is a precursor in the synthesis of 4-fluoro MDMB-BUTINACA (Item No. 26645). This product is intended for research and forensic applications.
Brand:CaymanSKU:27819 - 1 mgAvailable on backorder
4-fluoro Phenibut (hydrochloride) (Item No. 30232) is an analytical reference standard categorized as a gabapentinoid and is structurally similar to known nootropics.{53818} This product is intended for research and forensic applications.
Brand:CaymanSKU:30232 - 1 mgAvailable on backorder
4-fluoro Phenibut (hydrochloride) (Item No. 30232) is an analytical reference standard categorized as a gabapentinoid and is structurally similar to known nootropics.{53818} This product is intended for research and forensic applications.
Brand:CaymanSKU:30232 - 5 mgAvailable on backorder
4-fluoro U-47931E (Item No. 29563) is an analytical reference standard categorized as a utopioid. This product is intended for research and forensic applications.
Brand:CaymanSKU:29563 - 1 mgAvailable on backorder
4-fluoro U-47931E (Item No. 29563) is an analytical reference standard categorized as a utopioid. This product is intended for research and forensic applications.
Brand:CaymanSKU:29563 - 5 mgAvailable on backorder
4-fluoro-CUMYL-5-fluoro-PICA (Item No. 26131) is an analytical reference standard that is structurally similar to known synthetic cannabinoids. This product is intended for research and forensic applications.
Brand:CaymanSKU:26131 - 1 mgAvailable on backorder
4-fluoro-CUMYL-5-fluoro-PICA (Item No. 26131) is an analytical reference standard that is structurally similar to known synthetic cannabinoids. This product is intended for research and forensic applications.
Brand:CaymanSKU:26131 - 5 mgAvailable on backorder
4-fluoro-CUMYL-5-fluoro-PINACA (Item No. 26134) is an analytical reference standard categorized as a synthetic cannabinoid.{32921} This product is intended for research and forensic applications.
Brand:CaymanSKU:26134 - 1 mgAvailable on backorder
4-fluoro-CUMYL-5-fluoro-PINACA (Item No. 26134) is an analytical reference standard categorized as a synthetic cannabinoid.{32921} This product is intended for research and forensic applications.
Brand:CaymanSKU:26134 - 5 mgAvailable on backorder
4-Fluoro-L-phenylalanine is a non-proteinogenic amino acid and an inhibitor of protein synthesis.{47782,47783} It inhibits growth of MCF-7 breast cancer cells (IC50 = 11.8 μM).{47782} 4-Fluoro-L-phenylalanine reversibly inhibits stomatin-induced T. vorax macrostomal differentiation in a concentration-dependent manner.{47783} It has been used to replace phenylalanine residues in polypeptides for determining site-specific solvent accessibility by 19F-NMR.{47784}
Brand:CaymanSKU:29178 - 10 gAvailable on backorder
4-Fluoro-L-phenylalanine is a non-proteinogenic amino acid and an inhibitor of protein synthesis.{47782,47783} It inhibits growth of MCF-7 breast cancer cells (IC50 = 11.8 μM).{47782} 4-Fluoro-L-phenylalanine reversibly inhibits stomatin-induced T. vorax macrostomal differentiation in a concentration-dependent manner.{47783} It has been used to replace phenylalanine residues in polypeptides for determining site-specific solvent accessibility by 19F-NMR.{47784}
Brand:CaymanSKU:29178 - 25 gAvailable on backorder
4-Fluoro-L-phenylalanine is a non-proteinogenic amino acid and an inhibitor of protein synthesis.{47782,47783} It inhibits growth of MCF-7 breast cancer cells (IC50 = 11.8 μM).{47782} 4-Fluoro-L-phenylalanine reversibly inhibits stomatin-induced T. vorax macrostomal differentiation in a concentration-dependent manner.{47783} It has been used to replace phenylalanine residues in polypeptides for determining site-specific solvent accessibility by 19F-NMR.{47784}
Brand:CaymanSKU:29178 - 5 gAvailable on backorder
4-Fluoro-L-phenylalanine is a non-proteinogenic amino acid and an inhibitor of protein synthesis.{47782,47783} It inhibits growth of MCF-7 breast cancer cells (IC50 = 11.8 μM).{47782} 4-Fluoro-L-phenylalanine reversibly inhibits stomatin-induced T. vorax macrostomal differentiation in a concentration-dependent manner.{47783} It has been used to replace phenylalanine residues in polypeptides for determining site-specific solvent accessibility by 19F-NMR.{47784}
Brand:CaymanSKU:29178 - 50 gAvailable on backorder
α-Pyrrolidinopentiophenone (α-PVP; Item No. 9001083) is an analog of pyrovalerone (Item No. 10817), a known monoamine transport inhibitor that prevents the reuptake of dopamine and norepinephrine.{18946,18943} 4-fluoro-α-PVP is an isomer of α-PVP characterized by the addition of a fluorine group at the 4 position of the phenyl ring. The biochemical, physiological, and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:- α-Pyrrolidinopentiophenone (α-PVP; Item No. 9001083) is an analog of pyrovalerone (Item No. 10817), a known monoamine transport inhibitor that prevents the reuptake of dopamine and norepinephrine.{18946,18943} 4-fluoro-α-PVP is an isomer of α-PVP characterized by the addition of a fluorine group at the 4 position of the phenyl ring. The biochemical, physiological, and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:- α-Pyrrolidinopentiophenone (α-PVP; Item No. 9001083) is an analog of pyrovalerone (Item No. 10817), a known monoamine transport inhibitor that prevents the reuptake of dopamine and norepinephrine.{18946,18943} 4-fluoro-α-PVP is an isomer of α-PVP characterized by the addition of a fluorine group at the 4 position of the phenyl ring. The biochemical, physiological, and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:-
Halogenated amphetamines, including fluoroamphetamines (FAs), are psychostimulatory designer drugs.{20299,19913} para-Fluoroamphetamine (4-FA) (hydrochloride) inhibits the uptake of dopamine, serotonin, and norepinephrine with IC50 values of 0.77, 6.8, and 0.42 μM, respectively, indicating potency comparable to cocaine or methamphetamine.{19758} Methodology for detecting 4-FA in serum and urine using GC/MS has recently been described.{20298} This product is intended for forensic purposes.
Brand:CaymanSKU:11156 - 10 mgAvailable on backorder
Halogenated amphetamines, including fluoroamphetamines (FAs), are psychostimulatory designer drugs.{20299,19913} para-Fluoroamphetamine (4-FA) (hydrochloride) inhibits the uptake of dopamine, serotonin, and norepinephrine with IC50 values of 0.77, 6.8, and 0.42 μM, respectively, indicating potency comparable to cocaine or methamphetamine.{19758} Methodology for detecting 4-FA in serum and urine using GC/MS has recently been described.{20298} This product is intended for forensic purposes.
Brand:CaymanSKU:11156 - 5 mgAvailable on backorder
Halogenated amphetamines, including fluoroamphetamines (FAs), are psychostimulatory designer drugs.{20299,19913} para-Fluoroamphetamine (4-FA) (hydrochloride) inhibits the uptake of dopamine, serotonin, and norepinephrine with IC50 values of 0.77, 6.8, and 0.42 μM, respectively, indicating potency comparable to cocaine or methamphetamine.{19758} Methodology for detecting 4-FA in serum and urine using GC/MS has recently been described.{20298} This product is intended for forensic purposes.
Brand:CaymanSKU:11156 - 50 mgAvailable on backorder
4-Fluoroethamphetamine (hydrochloride) (Item No. 25811) is an analytical reference standard that is categorized as an amphetamine. This product is intended for research and forensic applications.
Brand:CaymanSKU:25811 - 1 mgAvailable on backorder
4-Fluoroethamphetamine (hydrochloride) (Item No. 25811) is an analytical reference standard that is categorized as an amphetamine. This product is intended for research and forensic applications.
Brand:CaymanSKU:25811 - 5 mgAvailable on backorder
4-Fluoromethamphetamine (4-FMA) is a stimulant drug related to methamphetamine and 4-fluoroamphetamine.{19913} Though little is known of the pharmacological properties of fluoro-methoxy-substituted amphetamines, 4-FMA has been identified as a component of designer drugs sold as “legal high” replacements for restricted substances.{19913} The hydrochloride formulation of this compound is intended for use as a standard for the forensic analysis of samples that may contain 4-FMA.
Brand:CaymanSKU:9001070 - 10 mgAvailable on backorder
4-Fluoromethamphetamine (4-FMA) is a stimulant drug related to methamphetamine and 4-fluoroamphetamine.{19913} Though little is known of the pharmacological properties of fluoro-methoxy-substituted amphetamines, 4-FMA has been identified as a component of designer drugs sold as “legal high” replacements for restricted substances.{19913} The hydrochloride formulation of this compound is intended for use as a standard for the forensic analysis of samples that may contain 4-FMA.
Brand:CaymanSKU:9001070 - 5 mgAvailable on backorder
4-Fluoromethamphetamine (4-FMA) is a stimulant drug related to methamphetamine and 4-fluoroamphetamine.{19913} Though little is known of the pharmacological properties of fluoro-methoxy-substituted amphetamines, 4-FMA has been identified as a component of designer drugs sold as “legal high” replacements for restricted substances.{19913} The hydrochloride formulation of this compound is intended for use as a standard for the forensic analysis of samples that may contain 4-FMA.
Brand:CaymanSKU:9001070 - 50 mgAvailable on backorder
4-Fluoromethcathinone (hydrochloride) (exempt preparation) (Item No. 16054) is an analytical reference standard categorized as a cathinone. 4-Fluoromethcathinone has been detected in products sold as plant food.{18958} 4-Fluoromethcathinone is regulated as a Schedule I compound in the United States. 4-Fluoromethcathinone (hydrochloride) (exempt preparation) (Item No. 16054) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.
Brand:CaymanSKU:-
4-Fluoromethcathinone (4-FMC) (Item No. 10859) is a fluorinated cathinone derivative identified in several designer drugs that are marketed as plant feeders.{19192,19498} This metabolite of 4-FMC features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,S and S,R orientations at carbons one and two, as in ephedrine. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research purposes.
Brand:CaymanSKU:- 4-Fluoromethcathinone (4-FMC) (Item No. 10859) is a fluorinated cathinone derivative identified in several designer drugs that are marketed as plant feeders.{19192,19498} This metabolite of 4-FMC features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,S and S,R orientations at carbons one and two, as in ephedrine. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research purposes.
Brand:CaymanSKU:- 4-Fluoromethcathinone (4-FMC) (Item No. 10859) is a fluorinated cathinone derivative identified in several designer drugs that are marketed as plant feeders.{19192,19498} This metabolite of 4-FMC features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,S and S,R orientations at carbons one and two, as in ephedrine. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research purposes.
Brand:CaymanSKU:-
4-Fluoromethcathinone (4-FMC) (Item No. 10859) is a fluorinated cathinone derivative identified in several designer drugs that are marketed as plant feeders.{19192,19498} This metabolite of 4-FMC (hydrochloride) features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,R and S,S orientations at carbons one and two, as in pseudoephedrine. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research purposes.
Brand:CaymanSKU:9001433 - 1 mgAvailable on backorder
4-Fluoromethcathinone (4-FMC) (Item No. 10859) is a fluorinated cathinone derivative identified in several designer drugs that are marketed as plant feeders.{19192,19498} This metabolite of 4-FMC (hydrochloride) features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,R and S,S orientations at carbons one and two, as in pseudoephedrine. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research purposes.
Brand:CaymanSKU:9001433 - 5 mgAvailable on backorder
4-Fluoromethcathinone (4-FMC) (Item No. 10859) is a fluorinated cathinone derivative identified in several designer drugs that are marketed as plant feeders.{19192,19498} This metabolite of 4-FMC (hydrochloride) features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,R and S,S orientations at carbons one and two, as in pseudoephedrine. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research purposes.
Brand:CaymanSKU:9001433 - 500 µgAvailable on backorder
A wide variety of aminoalkylindole analogs are potent synthetic cannabinoids (CBs), including many of the JWH compounds.{16798} An alkyl chain of five carbons in length produces compounds with high affinity for both the central CB1 and the peripheral CB2 receptors.{16797} The addition of a terminal fluorine to the pentyl chain can further increase affinity for both CB receptors.{18696} 4-Fluoropentylindole is the base structure for various synthetic CBs that features a fluorine at the 4 position of the pentyl chain. A range of structures can be added to this base via a ketone linkage at the 3 position of the indole. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.
Brand:CaymanSKU:- A wide variety of aminoalkylindole analogs are potent synthetic cannabinoids (CBs), including many of the JWH compounds.{16798} An alkyl chain of five carbons in length produces compounds with high affinity for both the central CB1 and the peripheral CB2 receptors.{16797} The addition of a terminal fluorine to the pentyl chain can further increase affinity for both CB receptors.{18696} 4-Fluoropentylindole is the base structure for various synthetic CBs that features a fluorine at the 4 position of the pentyl chain. A range of structures can be added to this base via a ketone linkage at the 3 position of the indole. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.
Brand:CaymanSKU:- A wide variety of aminoalkylindole analogs are potent synthetic cannabinoids (CBs), including many of the JWH compounds.{16798} An alkyl chain of five carbons in length produces compounds with high affinity for both the central CB1 and the peripheral CB2 receptors.{16797} The addition of a terminal fluorine to the pentyl chain can further increase affinity for both CB receptors.{18696} 4-Fluoropentylindole is the base structure for various synthetic CBs that features a fluorine at the 4 position of the pentyl chain. A range of structures can be added to this base via a ketone linkage at the 3 position of the indole. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.
Brand:CaymanSKU:-
Brand:CaymanSKU:10007086 - 1 gAvailable on backorder
Brand:CaymanSKU:10007086 - 10 gAvailable on backorder
Brand:CaymanSKU:10007086 - 5 gAvailable on backorder
Brand:CaymanSKU:10007086 - 500 mgAvailable on backorder
4-HOBA is an isomer of the isoketal scavenger 2-HOBA (Item No. 25357) that has reduced efficacy as an isoketal scavenger.{40882} Unlike 2-HOBA, 4-HOBA has no effect on hypertension induced by angiotensin II (Item No. 17150) in mice.{40882} 4-HOBA has been used as a negative control for the activity of 2-HOBA and related compounds in a mouse model of hypertension.{40882}
Brand:CaymanSKU:25398 - 10 gAvailable on backorder
4-HOBA is an isomer of the isoketal scavenger 2-HOBA (Item No. 25357) that has reduced efficacy as an isoketal scavenger.{40882} Unlike 2-HOBA, 4-HOBA has no effect on hypertension induced by angiotensin II (Item No. 17150) in mice.{40882} 4-HOBA has been used as a negative control for the activity of 2-HOBA and related compounds in a mouse model of hypertension.{40882}
Brand:CaymanSKU:25398 - 25 gAvailable on backorder
4-HOBA is an isomer of the isoketal scavenger 2-HOBA (Item No. 25357) that has reduced efficacy as an isoketal scavenger.{40882} Unlike 2-HOBA, 4-HOBA has no effect on hypertension induced by angiotensin II (Item No. 17150) in mice.{40882} 4-HOBA has been used as a negative control for the activity of 2-HOBA and related compounds in a mouse model of hypertension.{40882}
Brand:CaymanSKU:25398 - 5 gAvailable on backorder
4-HOBA is an isomer of the isoketal scavenger 2-HOBA (Item No. 25357) that has reduced efficacy as an isoketal scavenger.{40882} Unlike 2-HOBA, 4-HOBA has no effect on hypertension induced by angiotensin II (Item No. 17150) in mice.{40882} 4-HOBA has been used as a negative control for the activity of 2-HOBA and related compounds in a mouse model of hypertension.{40882}
Brand:CaymanSKU:25398 - 50 gAvailable on backorder
4-hydroxy Nonenal (4-HNE; Item No. 32100) is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress.{869,1103} 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity.{869,1103,1109} 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides.{10101} Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.
Brand:CaymanSKU:10004413 - 1 mgAvailable on backorder
4-hydroxy Nonenal (4-HNE; Item No. 32100) is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress.{869,1103} 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity.{869,1103,1109} 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides.{10101} Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.
Brand:CaymanSKU:10004413 - 10 mgAvailable on backorder
4-hydroxy Nonenal (4-HNE; Item No. 32100) is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress.{869,1103} 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity.{869,1103,1109} 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides.{10101} Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.
Brand:CaymanSKU:10004413 - 5 mgAvailable on backorder
4-hydroxy Nonenal (4-HNE; Item No. 32100) is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress.{869,1103} 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity.{869,1103,1109} 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides.{10101} Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.
Brand:CaymanSKU:10004413 - 500 µgAvailable on backorder
4-hydroperoxy Cyclophosphamide (4-OOH-CY) is the active metabolite form of the prodrug Cyclophosphamide (Item No. 13849). 4-OOH-CY crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS).{34375} Formulations containing the prodrug Cyclophosphamide are used to treat lymphomas and autoimmune disorders.{22688,21833}
Brand:CaymanSKU:-Available on backorder
4-hydroperoxy Cyclophosphamide (4-OOH-CY) is the active metabolite form of the prodrug Cyclophosphamide (Item No. 13849). 4-OOH-CY crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS).{34375} Formulations containing the prodrug Cyclophosphamide are used to treat lymphomas and autoimmune disorders.{22688,21833}
Brand:CaymanSKU:-Available on backorder
4-hydroperoxy Cyclophosphamide (4-OOH-CY) is the active metabolite form of the prodrug Cyclophosphamide (Item No. 13849). 4-OOH-CY crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS).{34375} Formulations containing the prodrug Cyclophosphamide are used to treat lymphomas and autoimmune disorders.{22688,21833}
Brand:CaymanSKU:-Available on backorder
4-hydroperoxy Cyclophosphamide (4-OOH-CY) is the active metabolite form of the prodrug Cyclophosphamide (Item No. 13849). 4-OOH-CY crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS).{34375} Formulations containing the prodrug Cyclophosphamide are used to treat lymphomas and autoimmune disorders.{22688,21833}
Brand:CaymanSKU:-Available on backorder
Alprazolam is a benzodiazepine with anxiolytic and sedative actions.{25991} 4-Hydroxyalprazolam is a major metabolite of alprazolam, produced by the actions of cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5.{25991,25993,25992} It may be detected in serum or, in a glucuronidated form, in urine.{25993} Alternatively, 4-hydroxyalprazolam can be further metabolized to benzophenone.{25993}
Brand:CaymanSKU:- Alprazolam is a benzodiazepine with anxiolytic and sedative actions.{25991} 4-Hydroxyalprazolam is a major metabolite of alprazolam, produced by the actions of cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5.{25991,25993,25992} It may be detected in serum or, in a glucuronidated form, in urine.{25993} Alternatively, 4-hydroxyalprazolam can be further metabolized to benzophenone.{25993}
Brand:CaymanSKU:-
4-hydroxy Alternariol is a metabolite of the mycotoxin alternariol (Item No. 11306) formed through cytochrome P450 (CYP450) metabolism.{41226} It increases reactive oxygen species (ROS) in KYSE510 human esophageal cells by 701% compared to control.{41227} 4-hydroxy Alternariol increases topoisomerase IIβ-DNA complexes by 208% compared to control in an ICE assay but does not induce DNA damage in KYSE510 cells. It completely inhibits topoisomerase IIα activity at a concentration of 25 µM under cell-free conditions.
Brand:CaymanSKU:23636 - 1 mgAvailable on backorder
4-hydroxy Alternariol is a metabolite of the mycotoxin alternariol (Item No. 11306) formed through cytochrome P450 (CYP450) metabolism.{41226} It increases reactive oxygen species (ROS) in KYSE510 human esophageal cells by 701% compared to control.{41227} 4-hydroxy Alternariol increases topoisomerase IIβ-DNA complexes by 208% compared to control in an ICE assay but does not induce DNA damage in KYSE510 cells. It completely inhibits topoisomerase IIα activity at a concentration of 25 µM under cell-free conditions.
Brand:CaymanSKU:23636 - 5 mgAvailable on backorder
4-hydroxy Alternariol is a metabolite of the mycotoxin alternariol (Item No. 11306) formed through cytochrome P450 (CYP450) metabolism.{41226} It increases reactive oxygen species (ROS) in KYSE510 human esophageal cells by 701% compared to control.{41227} 4-hydroxy Alternariol increases topoisomerase IIβ-DNA complexes by 208% compared to control in an ICE assay but does not induce DNA damage in KYSE510 cells. It completely inhibits topoisomerase IIα activity at a concentration of 25 µM under cell-free conditions.
Brand:CaymanSKU:23636 - 500 µgAvailable on backorder
4-Hydroxyamphetamine (4-HA) is a bioactive metabolite of amphetamine.{24225,24227} This sympathomimetic is an agonist of the trace amine-associated receptor 1 (EC50 = ~0.2 μM in HEK293 cells expressing rat TAAR1).{24228} As a 1% ophthalmologic solution, 4-HA has been used to dilate the pupil in the diagnosis of Horner’s syndrome.{24224,24226} This product is intended only for forensic and research purposes.
Brand:CaymanSKU:9001830 - 10 mgAvailable on backorder
4-Hydroxyamphetamine (4-HA) is a bioactive metabolite of amphetamine.{24225,24227} This sympathomimetic is an agonist of the trace amine-associated receptor 1 (EC50 = ~0.2 μM in HEK293 cells expressing rat TAAR1).{24228} As a 1% ophthalmologic solution, 4-HA has been used to dilate the pupil in the diagnosis of Horner’s syndrome.{24224,24226} This product is intended only for forensic and research purposes.
Brand:CaymanSKU:9001830 - 5 mgAvailable on backorder
4-Hydroxyamphetamine (4-HA) is a bioactive metabolite of amphetamine.{24225,24227} This sympathomimetic is an agonist of the trace amine-associated receptor 1 (EC50 = ~0.2 μM in HEK293 cells expressing rat TAAR1).{24228} As a 1% ophthalmologic solution, 4-HA has been used to dilate the pupil in the diagnosis of Horner’s syndrome.{24224,24226} This product is intended only for forensic and research purposes.
Brand:CaymanSKU:9001830 - 50 mgAvailable on backorder
4-hydroxy Atorvastatin is a metabolite of atorvastatin (Item No. 10493), an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.{18329,18240,18241,18235} Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin.{18329}
Brand:CaymanSKU:22575 -Out of stock
4-hydroxy Atorvastatin is a metabolite of atorvastatin (Item No. 10493), an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.{18329,18240,18241,18235} Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin.{18329}
Brand:CaymanSKU:22575 -Out of stock
4-hydroxy Atorvastatin is a metabolite of atorvastatin (Item No. 10493), an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.{18329,18240,18241,18235} Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin.{18329}
Brand:CaymanSKU:22575 -Out of stock
4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin (Item No. 10493), an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.{18239,18240,18241,18235} Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin (Item No. 22575) and 2-hydroxy atorvastatin, which can be interconverted between their acid and lactone forms.{18239} Atorvastatin can itself be lactonized to atorvastatin lactone (Item No. 20951) then metabolized by CYP3A4 directly to 4-hydroxy atorvastatin lactone and 2-hydroxy atorvastatin lactone.
Brand:CaymanSKU:23358 - 1 mgAvailable on backorder
4-hydroxy Diethyltryptamine (4-hydroxy DET) is a substituted tryptamine which is structurally related to the natural hallucinogen psilocin (4-hydroxy dimethyltryptamine). 4-hydroxy DET is a designer drug of abuse.{22648} The physiological and toxicological properties of this compound are poorly studied. This product is intended for forensic and research purposes.
Brand:CaymanSKU:- 4-hydroxy Diethyltryptamine (4-hydroxy DET) is a substituted tryptamine which is structurally related to the natural hallucinogen psilocin (4-hydroxy dimethyltryptamine). 4-hydroxy DET is a designer drug of abuse.{22648} The physiological and toxicological properties of this compound are poorly studied. This product is intended for forensic and research purposes.
Brand:CaymanSKU:- 4-hydroxy Diethyltryptamine (4-hydroxy DET) is a substituted tryptamine which is structurally related to the natural hallucinogen psilocin (4-hydroxy dimethyltryptamine). 4-hydroxy DET is a designer drug of abuse.{22648} The physiological and toxicological properties of this compound are poorly studied. This product is intended for forensic and research purposes.
Brand:CaymanSKU:-