Cayman
Showing 5701–5850 of 45550 results
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4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a tobacco-specific nitrosamine carcinogen.{45973} Reactive metabolites of NNK alkylate DNA, forming pyridyloxobutyl (POB) and pyridylhydroxybutyl (PHB) adducts, and induce DNA methylation. NNK (100 mg/kg, single dose) increases the protein levels of DNA methyltransferase 1 (DNMT1) in mouse bronchial epithelial cells within one day and increases hypermethylation of the tumor suppressor genes Chd13, Prdm2, and Runx3 in lung tissue within three days.{45974} It induces tumor formation preferentially in the lung via various routes of administration in animal models.{45975} NNK induces adenomas and adenocarcinomas, which are present after 16 and 50 weeks, respectively, in mouse lung when administered at a single dose of 10 µmol/animal. Lifetime administration of NNK (63.5 mg/animal) to rats results in a 90% incidence of lung tumors.{45976}
Brand:CaymanSKU:-Out of stock
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4-(N-Boc-amino)piperidine is an organic building block.{49620,49621} It has been used in the synthesis of aminopiperidine antiviral chemokine (C-C motif) receptor 5 (CCR5) antagonists and antibacterial agents.
Brand:CaymanSKU:30398 - 1 gAvailable on backorder
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4-(N-Boc-amino)piperidine is an organic building block.{49620,49621} It has been used in the synthesis of aminopiperidine antiviral chemokine (C-C motif) receptor 5 (CCR5) antagonists and antibacterial agents.
Brand:CaymanSKU:30398 - 5 gAvailable on backorder
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Fatty acid amide hydrolase (FAAH) is the primary enzyme responsible for the hydrolysis of the endocannabinoid arachidonoyl ethanolamide (AEA). 4-(n-Nonyl) benzeneboronic acid is a potent inhibitor of FAAH, with an IC50 of 9.1 nM.{16557} It is also able to inhibit monoacylglycerol lipase (MAGL), which hydrolyzes 2-arachidonoyl glycerol (2-AG), but at ~1000-fold higher concentration (IC50 = 7.9 μM).{16557}
Brand:CaymanSKU:- -
Fatty acid amide hydrolase (FAAH) is the primary enzyme responsible for the hydrolysis of the endocannabinoid arachidonoyl ethanolamide (AEA). 4-(n-Nonyl) benzeneboronic acid is a potent inhibitor of FAAH, with an IC50 of 9.1 nM.{16557} It is also able to inhibit monoacylglycerol lipase (MAGL), which hydrolyzes 2-arachidonoyl glycerol (2-AG), but at ~1000-fold higher concentration (IC50 = 7.9 μM).{16557}
Brand:CaymanSKU:- -
Fatty acid amide hydrolase (FAAH) is the primary enzyme responsible for the hydrolysis of the endocannabinoid arachidonoyl ethanolamide (AEA). 4-(n-Nonyl) benzeneboronic acid is a potent inhibitor of FAAH, with an IC50 of 9.1 nM.{16557} It is also able to inhibit monoacylglycerol lipase (MAGL), which hydrolyzes 2-arachidonoyl glycerol (2-AG), but at ~1000-fold higher concentration (IC50 = 7.9 μM).{16557}
Brand:CaymanSKU:- -
Fatty acid amide hydrolase (FAAH) is the primary enzyme responsible for the hydrolysis of the endocannabinoid arachidonoyl ethanolamide (AEA). 4-(n-Nonyl) benzeneboronic acid is a potent inhibitor of FAAH, with an IC50 of 9.1 nM.{16557} It is also able to inhibit monoacylglycerol lipase (MAGL), which hydrolyzes 2-arachidonoyl glycerol (2-AG), but at ~1000-fold higher concentration (IC50 = 7.9 μM).{16557}
Brand:CaymanSKU:- -
4-(Neopentyloxysulfonyl)phenylboronic acid is a monosulfonic acid that has been used as a building block in the synthesis of water-soluble dibenzothiophene (DBT) and dibenzothiophene S-oxide (DBTO) derivatives.{41871}
Brand:CaymanSKU:21493 -Out of stock
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4-(Neopentyloxysulfonyl)phenylboronic acid is a monosulfonic acid that has been used as a building block in the synthesis of water-soluble dibenzothiophene (DBT) and dibenzothiophene S-oxide (DBTO) derivatives.{41871}
Brand:CaymanSKU:21493 -Out of stock
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4-(Neopentyloxysulfonyl)phenylboronic acid is a monosulfonic acid that has been used as a building block in the synthesis of water-soluble dibenzothiophene (DBT) and dibenzothiophene S-oxide (DBTO) derivatives.{41871}
Brand:CaymanSKU:21493 -Out of stock
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4-(Phenylcarbonyl)benzoic acid is a photooxidant.{52473,52474,52476} Upon light activation, 4-(phenylcarbonyl)benzoic acid forms an electrophilic aromatic ketone that acts as an oxidant in organic synthesis or biological systems. It has been used in the study of amino acid oxidation, as well as the synthesis of photoactivated antibacterial and antiviral compounds.
Brand:CaymanSKU:30407 - 1 gAvailable on backorder
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4-(Phenylcarbonyl)benzoic acid is a photooxidant.{52473,52474,52476} Upon light activation, 4-(phenylcarbonyl)benzoic acid forms an electrophilic aromatic ketone that acts as an oxidant in organic synthesis or biological systems. It has been used in the study of amino acid oxidation, as well as the synthesis of photoactivated antibacterial and antiviral compounds.
Brand:CaymanSKU:30407 - 10 gAvailable on backorder
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4-(Phenylcarbonyl)benzoic acid is a photooxidant.{52473,52474,52476} Upon light activation, 4-(phenylcarbonyl)benzoic acid forms an electrophilic aromatic ketone that acts as an oxidant in organic synthesis or biological systems. It has been used in the study of amino acid oxidation, as well as the synthesis of photoactivated antibacterial and antiviral compounds.
Brand:CaymanSKU:30407 - 5 gAvailable on backorder
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4-Acetamidobutyric acid is a GABA derivative.{48926} Urinary levels of 4-acetamidobutyric acid are elevated in patients with stage 5 chronic kidney disease compared to patients with stage 3 kidney disease and those without kidney disease.
Brand:CaymanSKU:29881 - 1 gAvailable on backorder
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4-Acetamidobutyric acid is a GABA derivative.{48926} Urinary levels of 4-acetamidobutyric acid are elevated in patients with stage 5 chronic kidney disease compared to patients with stage 3 kidney disease and those without kidney disease.
Brand:CaymanSKU:29881 - 10 gAvailable on backorder
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4-Acetamidobutyric acid is a GABA derivative.{48926} Urinary levels of 4-acetamidobutyric acid are elevated in patients with stage 5 chronic kidney disease compared to patients with stage 3 kidney disease and those without kidney disease.
Brand:CaymanSKU:29881 - 25 gAvailable on backorder
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4-Acetamidobutyric acid is a GABA derivative.{48926} Urinary levels of 4-acetamidobutyric acid are elevated in patients with stage 5 chronic kidney disease compared to patients with stage 3 kidney disease and those without kidney disease.
Brand:CaymanSKU:29881 - 5 gAvailable on backorder
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4-acetoxy MPT (Item No. 26494) is an analytical reference standard categorized as a tryptamine. This product is intended for research and forensic applications.
Brand:CaymanSKU:26494 - 1 mgAvailable on backorder
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4-acetoxy MPT (Item No. 26494) is an analytical reference standard categorized as a tryptamine. This product is intended for research and forensic applications.
Brand:CaymanSKU:26494 - 5 mgAvailable on backorder
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Brand:CaymanSKU:11053 - 1 g
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Brand:CaymanSKU:11053 - 5 g
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Brand:CaymanSKU:11053 - 500 mg
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Brand:CaymanSKU:11063 - 1 g
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Brand:CaymanSKU:11063 - 5 g
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Brand:CaymanSKU:11063 - 500 mg
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4-amino Nicotinic acid is a synthetic intermediate that has been used in various syntheses.{32526,32527}
Brand:CaymanSKU:20733 -Available on backorder
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4-amino Nicotinic acid is a synthetic intermediate that has been used in various syntheses.{32526,32527}
Brand:CaymanSKU:20733 -Available on backorder
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4-amino Nicotinic acid is a synthetic intermediate that has been used in various syntheses.{32526,32527}
Brand:CaymanSKU:20733 -Available on backorder
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4-amino Nicotinic acid is a synthetic intermediate that has been used in various syntheses.{32526,32527}
Brand:CaymanSKU:20733 -Available on backorder
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The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species.{22577,22591} 4-amino-1,8-Naphthalimide (4-ANI) is an inhibitor of PARP (IC50 = 180 nM).{22573} It blocks radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation, although it is not cytotoxic in the absence of radiation.{29753} 4-ANI is used to study the role of PARP activity in various cell systems.{25755,29751,29752}
Brand:CaymanSKU:-Available on backorder
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The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species.{22577,22591} 4-amino-1,8-Naphthalimide (4-ANI) is an inhibitor of PARP (IC50 = 180 nM).{22573} It blocks radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation, although it is not cytotoxic in the absence of radiation.{29753} 4-ANI is used to study the role of PARP activity in various cell systems.{25755,29751,29752}
Brand:CaymanSKU:-Available on backorder
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The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species.{22577,22591} 4-amino-1,8-Naphthalimide (4-ANI) is an inhibitor of PARP (IC50 = 180 nM).{22573} It blocks radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation, although it is not cytotoxic in the absence of radiation.{29753} 4-ANI is used to study the role of PARP activity in various cell systems.{25755,29751,29752}
Brand:CaymanSKU:-Available on backorder
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The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species.{22577,22591} 4-amino-1,8-Naphthalimide (4-ANI) is an inhibitor of PARP (IC50 = 180 nM).{22573} It blocks radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation, although it is not cytotoxic in the absence of radiation.{29753} 4-ANI is used to study the role of PARP activity in various cell systems.{25755,29751,29752}
Brand:CaymanSKU:-Available on backorder
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4-Amino-5-(bromomethyl)-2-methylpyrimidine is a heterocyclic building block.{53382,53383} It has been used in the synthesis of vitamin B1 analogs and thiaminephosphoric acid esters.
Brand:CaymanSKU:29839 - 10 mgAvailable on backorder
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4-Amino-5-(bromomethyl)-2-methylpyrimidine is a heterocyclic building block.{53382,53383} It has been used in the synthesis of vitamin B1 analogs and thiaminephosphoric acid esters.
Brand:CaymanSKU:29839 - 25 mgAvailable on backorder
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4-Amino-5-(bromomethyl)-2-methylpyrimidine is a heterocyclic building block.{53382,53383} It has been used in the synthesis of vitamin B1 analogs and thiaminephosphoric acid esters.
Brand:CaymanSKU:29839 - 5 mgAvailable on backorder
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4-Amino-5-(bromomethyl)-2-methylpyrimidine is a heterocyclic building block.{53382,53383} It has been used in the synthesis of vitamin B1 analogs and thiaminephosphoric acid esters.
Brand:CaymanSKU:29839 - 50 mgAvailable on backorder
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4-Aminobenzoic acid, commonly known as PABA, is an intermediate in the synthesis of tetrahydrofolic acid (Item No. 18263) in many non-mammalian organisms, including bacteria and fungi. {30200} Folates, like tetrahydrofolic acid, have critical roles in the metabolism of nucleic acid precursors and several amino acids, as well as in methylation reactions.{29515} In mammals, PABA is metabolized by a variety of enzymes, including N-acetyltransferases.{30198} It may also be utilized by bacteria or fungi that are living in mammalian organisms, including those resident in the gut.{30199}
Brand:CaymanSKU:-Available on backorder
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4-Aminobenzoic acid, commonly known as PABA, is an intermediate in the synthesis of tetrahydrofolic acid (Item No. 18263) in many non-mammalian organisms, including bacteria and fungi. {30200} Folates, like tetrahydrofolic acid, have critical roles in the metabolism of nucleic acid precursors and several amino acids, as well as in methylation reactions.{29515} In mammals, PABA is metabolized by a variety of enzymes, including N-acetyltransferases.{30198} It may also be utilized by bacteria or fungi that are living in mammalian organisms, including those resident in the gut.{30199}
Brand:CaymanSKU:-Available on backorder
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4-Aminobenzoic acid, commonly known as PABA, is an intermediate in the synthesis of tetrahydrofolic acid (Item No. 18263) in many non-mammalian organisms, including bacteria and fungi. {30200} Folates, like tetrahydrofolic acid, have critical roles in the metabolism of nucleic acid precursors and several amino acids, as well as in methylation reactions.{29515} In mammals, PABA is metabolized by a variety of enzymes, including N-acetyltransferases.{30198} It may also be utilized by bacteria or fungi that are living in mammalian organisms, including those resident in the gut.{30199}
Brand:CaymanSKU:-Available on backorder
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4-Aminobenzoic acid, commonly known as PABA, is an intermediate in the synthesis of tetrahydrofolic acid (Item No. 18263) in many non-mammalian organisms, including bacteria and fungi. {30200} Folates, like tetrahydrofolic acid, have critical roles in the metabolism of nucleic acid precursors and several amino acids, as well as in methylation reactions.{29515} In mammals, PABA is metabolized by a variety of enzymes, including N-acetyltransferases.{30198} It may also be utilized by bacteria or fungi that are living in mammalian organisms, including those resident in the gut.{30199}
Brand:CaymanSKU:-Available on backorder
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Myeloperoxidase is an enzyme, produced by neutrophils and other myeloid cells, that is released upon degranulation.{16905,16661} 4-Aminobenzoic acid hydrazide (4-ABAH) is an ABAH that specifically and irreversibly inhibits the peroxidation activity of myeloperoxidase (IC50 = 0.3 μM).{16906,16907} This compound can be used with enzyme preparations, in cell cultures, and also in vivo.{16906,23608,23609,23607}
Brand:CaymanSKU:- -
Myeloperoxidase is an enzyme, produced by neutrophils and other myeloid cells, that is released upon degranulation.{16905,16661} 4-Aminobenzoic acid hydrazide (4-ABAH) is an ABAH that specifically and irreversibly inhibits the peroxidation activity of myeloperoxidase (IC50 = 0.3 μM).{16906,16907} This compound can be used with enzyme preparations, in cell cultures, and also in vivo.{16906,23608,23609,23607}
Brand:CaymanSKU:- -
4-Aminohippuric acid is a substrate for various renal transporters that has been used in the study of anion uptake in the kidney. It is a substrate for organic anion transporter 1 (OAT1; Km = 14.3 µM in X. laevis oocytes), the human inorganic phosphate transporter (NPT1; Km = 2.66 mM in HEK293 cells), and apical multidrug resistance protein (MDR2; Km = 880 µM in HEK293 cells).{38433,38434,38432} 4-Aminohippuric acid is a glycine amide form of 4-aminobenzoic acid (Item No. 18659). Formulations containing 4-aminohippuric acid have been used as markers to determine renal plasma flow.
Brand:CaymanSKU:23726 - 10 gAvailable on backorder
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4-Aminohippuric acid is a substrate for various renal transporters that has been used in the study of anion uptake in the kidney. It is a substrate for organic anion transporter 1 (OAT1; Km = 14.3 µM in X. laevis oocytes), the human inorganic phosphate transporter (NPT1; Km = 2.66 mM in HEK293 cells), and apical multidrug resistance protein (MDR2; Km = 880 µM in HEK293 cells).{38433,38434,38432} 4-Aminohippuric acid is a glycine amide form of 4-aminobenzoic acid (Item No. 18659). Formulations containing 4-aminohippuric acid have been used as markers to determine renal plasma flow.
Brand:CaymanSKU:23726 - 5 gAvailable on backorder
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Brand:CaymanSKU:10007085 - 1 g
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Brand:CaymanSKU:10007085 - 5 g
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Brand:CaymanSKU:10007085 - 500 mg
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4-Aminophenyl phosphate is a substrate for alkaline phosphatase (ALP) that can be used in enzymatic reactions to quantify ALP activity.{28215,28216} The enzymatic reaction results in the production of phenol, which is used to determine ALP concentrations.{28215}
Brand:CaymanSKU:-Available on backorder
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4-Aminophenyl phosphate is a substrate for alkaline phosphatase (ALP) that can be used in enzymatic reactions to quantify ALP activity.{28215,28216} The enzymatic reaction results in the production of phenol, which is used to determine ALP concentrations.{28215}
Brand:CaymanSKU:-Available on backorder
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4-Aminophenyl phosphate is a substrate for alkaline phosphatase (ALP) that can be used in enzymatic reactions to quantify ALP activity.{28215,28216} The enzymatic reaction results in the production of phenol, which is used to determine ALP concentrations.{28215}
Brand:CaymanSKU:-Available on backorder
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4-Aminophenyl phosphate is a substrate for alkaline phosphatase (ALP) that can be used in enzymatic reactions to quantify ALP activity.{28215,28216} The enzymatic reaction results in the production of phenol, which is used to determine ALP concentrations.{28215}
Brand:CaymanSKU:-Available on backorder
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4-Aminophenylphosphorylcholine is a probe that can be conjugated to sepharose in order to generate an adsorbent for use in affinity precipitation experiments.{32927}
Brand:CaymanSKU:20643 -Available on backorder
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4-Aminophenylphosphorylcholine is a probe that can be conjugated to sepharose in order to generate an adsorbent for use in affinity precipitation experiments.{32927}
Brand:CaymanSKU:20643 -Available on backorder
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4-Aminophenylphosphorylcholine is a probe that can be conjugated to sepharose in order to generate an adsorbent for use in affinity precipitation experiments.{32927}
Brand:CaymanSKU:20643 -Available on backorder
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4-Aminopyridine (4-AP) is a non-selective blocker of voltage-dependent K+-channels (Kv proteins in the KCN gene family). It has greatest potency at Kv1 (KCNA) and Kv3 (KCNC) family members (IC50s = 290, 590, 195, 13, 29, and 100 µM for subunits 1.1, 1.2, 1.3, 1.4, 3.1, and 3.2, respectively).{29898} 4-AP also blocks Kv2 and Kv4 subunits at millimolar concentrations.{29898} When administered orally, 4-AP has benefits against multiple sclerosis, while injection into the brain produces epileptiform activity and can be used to study seizures.{29897,29899,29900}
Brand:CaymanSKU:-Available on backorder
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4-Aminopyridine (4-AP) is a non-selective blocker of voltage-dependent K+-channels (Kv proteins in the KCN gene family). It has greatest potency at Kv1 (KCNA) and Kv3 (KCNC) family members (IC50s = 290, 590, 195, 13, 29, and 100 µM for subunits 1.1, 1.2, 1.3, 1.4, 3.1, and 3.2, respectively).{29898} 4-AP also blocks Kv2 and Kv4 subunits at millimolar concentrations.{29898} When administered orally, 4-AP has benefits against multiple sclerosis, while injection into the brain produces epileptiform activity and can be used to study seizures.{29897,29899,29900}
Brand:CaymanSKU:-Available on backorder
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4-Aminopyridine (4-AP) is a non-selective blocker of voltage-dependent K+-channels (Kv proteins in the KCN gene family). It has greatest potency at Kv1 (KCNA) and Kv3 (KCNC) family members (IC50s = 290, 590, 195, 13, 29, and 100 µM for subunits 1.1, 1.2, 1.3, 1.4, 3.1, and 3.2, respectively).{29898} 4-AP also blocks Kv2 and Kv4 subunits at millimolar concentrations.{29898} When administered orally, 4-AP has benefits against multiple sclerosis, while injection into the brain produces epileptiform activity and can be used to study seizures.{29897,29899,29900}
Brand:CaymanSKU:-Available on backorder
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4-Aminopyridine (4-AP) is a non-selective blocker of voltage-dependent K+-channels (Kv proteins in the KCN gene family). It has greatest potency at Kv1 (KCNA) and Kv3 (KCNC) family members (IC50s = 290, 590, 195, 13, 29, and 100 µM for subunits 1.1, 1.2, 1.3, 1.4, 3.1, and 3.2, respectively).{29898} 4-AP also blocks Kv2 and Kv4 subunits at millimolar concentrations.{29898} When administered orally, 4-AP has benefits against multiple sclerosis, while injection into the brain produces epileptiform activity and can be used to study seizures.{29897,29899,29900}
Brand:CaymanSKU:-Available on backorder
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4-Anilino-1-benzylpiperidine (Item No. 20086) is an analytical reference standard that is categorized as an impurity of certain opioids. It has been identified as an impurity of fentanyl (Item Nos. ISO60197 | 14719) and its analogs. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Brand:CaymanSKU:20086 -Available on backorder
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4-Anilino-1-benzylpiperidine (Item No. 20086) is an analytical reference standard that is categorized as an impurity of certain opioids. It has been identified as an impurity of fentanyl (Item Nos. ISO60197 | 14719) and its analogs. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Brand:CaymanSKU:20086 -Available on backorder
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4-APB is a positional isomer of the designer drug 6-APB (Item No. 11079), also known as benzo fury, found in recreational drugs.{22885} It is expected to have psychoactive effects similar to 6-APB. 4-APB is also an analog of MDA (Item No. 11554) in which the 3,4-methylenedioxyphenyl ring system has been replaced with a benzofuran ring. This product is intended for forensic and research applications.
Brand:CaymanSKU:- -
4-APB is a positional isomer of the designer drug 6-APB (Item No. 11079), also known as benzo fury, found in recreational drugs.{22885} It is expected to have psychoactive effects similar to 6-APB. 4-APB is also an analog of MDA (Item No. 11554) in which the 3,4-methylenedioxyphenyl ring system has been replaced with a benzofuran ring. This product is intended for forensic and research applications.
Brand:CaymanSKU:- -
4-APB is a positional isomer of the designer drug 6-APB (Item No. 11079), also known as benzo fury, found in recreational drugs.{22885} It is expected to have psychoactive effects similar to 6-APB. 4-APB is also an analog of MDA (Item No. 11554) in which the 3,4-methylenedioxyphenyl ring system has been replaced with a benzofuran ring. This product is intended for forensic and research applications.
Brand:CaymanSKU:- -
Amphetamines designed with 2,3-dihydrobenzofuran in place of the phenyl group include the entactogens 5-APDB (Item No. 11456) and 6-APDB (Item No. 11146). These designer drugs can inhibit monoamine uptake.{21930} 4-APDB is an analog of 5- and 6-APDB. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:9001891 - 1 mgAvailable on backorder
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Amphetamines designed with 2,3-dihydrobenzofuran in place of the phenyl group include the entactogens 5-APDB (Item No. 11456) and 6-APDB (Item No. 11146). These designer drugs can inhibit monoamine uptake.{21930} 4-APDB is an analog of 5- and 6-APDB. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:9001891 - 10 mgAvailable on backorder
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Amphetamines designed with 2,3-dihydrobenzofuran in place of the phenyl group include the entactogens 5-APDB (Item No. 11456) and 6-APDB (Item No. 11146). These designer drugs can inhibit monoamine uptake.{21930} 4-APDB is an analog of 5- and 6-APDB. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
Brand:CaymanSKU:9001891 - 5 mgAvailable on backorder
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Brand:CaymanSKU:10550 - 1 g
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Brand:CaymanSKU:10550 - 100 mg
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Brand:CaymanSKU:10550 - 250 mg
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Brand:CaymanSKU:10550 - 500 mg
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4-bromo A23187 is a halogenated analog of the highly selective calcium ionophore A23187 (Item No. 11016). 4-bromo A23187 is non-fluorescent.{31997} As a result, it is often used in experiments where fluorescent probes are employed.{31998,31999}
Brand:CaymanSKU:20438 -Available on backorder
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4-bromo A23187 is a halogenated analog of the highly selective calcium ionophore A23187 (Item No. 11016). 4-bromo A23187 is non-fluorescent.{31997} As a result, it is often used in experiments where fluorescent probes are employed.{31998,31999}
Brand:CaymanSKU:20438 -Available on backorder
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4-bromo A23187 is a halogenated analog of the highly selective calcium ionophore A23187 (Item No. 11016). 4-bromo A23187 is non-fluorescent.{31997} As a result, it is often used in experiments where fluorescent probes are employed.{31998,31999}
Brand:CaymanSKU:20438 -Available on backorder
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4-bromo-2,5-DMA is a common hallucinogenic designer drug that avidly binds and activates serotonin receptors (Kis= 2.2 and 2.8 nM for 5-HT2A and 5-HT2C, respectively).{21282,21376} Methods have been developed for the identification of this compound in serum and in urine.{21281,21517} This product is intended for research and forensic applications.
Brand:CaymanSKU:- -
4-bromo-2,5-Dimethoxymethamphetamine is a designer drug patterned after 2,5-dimethylamphetamine compounds on the illicit drug market.{24049,20771} The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research purposes.
Brand:CaymanSKU:- -
4-bromo-2,5-Dimethoxymethamphetamine is a designer drug patterned after 2,5-dimethylamphetamine compounds on the illicit drug market.{24049,20771} The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research purposes.
Brand:CaymanSKU:- -
4-bromo-2,5-Dimethoxymethamphetamine is a designer drug patterned after 2,5-dimethylamphetamine compounds on the illicit drug market.{24049,20771} The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research purposes.
Brand:CaymanSKU:- -
4-bromo-α-Pyrrolidinovalerophenone (hydrochloride) (Item No. 19329) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
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4-bromo-α-Pyrrolidinovalerophenone (hydrochloride) (Item No. 19329) is an analytical reference standard categorized as a cathinone. This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
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4-Bromoamphetamine is a para-substituted amphetamine that acts as a monoamine releasing agent.{25537,25538} It is highly neurotoxic, producing long-term depletion of serotonin.{25537,25538} This product is intended only for forensic and research purposes.
Brand:CaymanSKU:9001850 - 10 mgAvailable on backorder
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4-Bromoamphetamine is a para-substituted amphetamine that acts as a monoamine releasing agent.{25537,25538} It is highly neurotoxic, producing long-term depletion of serotonin.{25537,25538} This product is intended only for forensic and research purposes.
Brand:CaymanSKU:9001850 - 5 mgAvailable on backorder
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4-Bromoamphetamine is a para-substituted amphetamine that acts as a monoamine releasing agent.{25537,25538} It is highly neurotoxic, producing long-term depletion of serotonin.{25537,25538} This product is intended only for forensic and research purposes.
Brand:CaymanSKU:9001850 - 50 mgAvailable on backorder
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4-Bromoethcathinone (hydrochloride) (Item No. 17395) is an analytical reference standard that is structurally categorized as a cathinone. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
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4-Bromoethcathinone (hydrochloride) (Item No. 17395) is an analytical reference standard that is structurally categorized as a cathinone. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
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4-CAB is an analog of p-chloroamphetamine, a psychoactive compound which shows pronounced toxicity for serotonergic neurons.{22305,21515} 4-CAB inhibits the reuptake of serotonin (IC50 = 330 nM) and dopamine (IC50 = 2.3 μM).{22305} This product is intended for forensic and research applications.
Brand:CaymanSKU:- -
4-CAB is an analog of p-chloroamphetamine, a psychoactive compound which shows pronounced toxicity for serotonergic neurons.{22305,21515} 4-CAB inhibits the reuptake of serotonin (IC50 = 330 nM) and dopamine (IC50 = 2.3 μM).{22305} This product is intended for forensic and research applications.
Brand:CaymanSKU:- -
4-CAB is an analog of p-chloroamphetamine, a psychoactive compound which shows pronounced toxicity for serotonergic neurons.{22305,21515} 4-CAB inhibits the reuptake of serotonin (IC50 = 330 nM) and dopamine (IC50 = 2.3 μM).{22305} This product is intended for forensic and research applications.
Brand:CaymanSKU:- -
4-carboxy TEMPO is a nitroxide and spin label.{40632} Nitroxides such as 4-carboxy TEMPO react with reactive oxygen species (ROS) and can be used with electron spin resonance (ESR) spectroscopy to monitor ROS production in vivo.{40632},{40634} It has also been used to study flavin-photosensitized damage in inner mitochondrial membranes.{40633}
Brand:CaymanSKU:23139 - 100 mgAvailable on backorder
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4-carboxy TEMPO is a nitroxide and spin label.{40632} Nitroxides such as 4-carboxy TEMPO react with reactive oxygen species (ROS) and can be used with electron spin resonance (ESR) spectroscopy to monitor ROS production in vivo.{40632},{40634} It has also been used to study flavin-photosensitized damage in inner mitochondrial membranes.{40633}
Brand:CaymanSKU:23139 - 250 mgAvailable on backorder
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4-carboxy TEMPO is a nitroxide and spin label.{40632} Nitroxides such as 4-carboxy TEMPO react with reactive oxygen species (ROS) and can be used with electron spin resonance (ESR) spectroscopy to monitor ROS production in vivo.{40632},{40634} It has also been used to study flavin-photosensitized damage in inner mitochondrial membranes.{40633}
Brand:CaymanSKU:23139 - 50 mgAvailable on backorder
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4-carboxy TEMPO is a nitroxide and spin label.{40632} Nitroxides such as 4-carboxy TEMPO react with reactive oxygen species (ROS) and can be used with electron spin resonance (ESR) spectroscopy to monitor ROS production in vivo.{40632},{40634} It has also been used to study flavin-photosensitized damage in inner mitochondrial membranes.{40633}
Brand:CaymanSKU:23139 - 500 mgAvailable on backorder
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4-chloro CUMYL-PINACA (Item No. 26132) is an analytical reference standard that is structurally similar to known synthetic cannabinoids. This product is intended for research and forensic applications.
Brand:CaymanSKU:26132 - 1 mgAvailable on backorder
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4-chloro CUMYL-PINACA (Item No. 26132) is an analytical reference standard that is structurally similar to known synthetic cannabinoids. This product is intended for research and forensic applications.
Brand:CaymanSKU:26132 - 5 mgAvailable on backorder
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2,5-Dimethoxyamphetamine (2,5-DMA) (Item No. 9001314) and its 4-substituted analogs are designer drugs which activate the serotonin 5-HT2 receptors.{21376,20771,21281} 4-chloro-2,5-Dimethoxyamphetamine (4-chloro-2,5-DMA) is an analog of 2,5-DMA which can be found on the illicit drug market.{20771} Its physiological and toxicological properties are poorly understood. This product is intended for research and forensic applications.
Brand:CaymanSKU:12038 - 1 mgAvailable on backorder
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2,5-Dimethoxyamphetamine (2,5-DMA) (Item No. 9001314) and its 4-substituted analogs are designer drugs which activate the serotonin 5-HT2 receptors.{21376,20771,21281} 4-chloro-2,5-Dimethoxyamphetamine (4-chloro-2,5-DMA) is an analog of 2,5-DMA which can be found on the illicit drug market.{20771} Its physiological and toxicological properties are poorly understood. This product is intended for research and forensic applications.
Brand:CaymanSKU:12038 - 10 mgAvailable on backorder
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2,5-Dimethoxyamphetamine (2,5-DMA) (Item No. 9001314) and its 4-substituted analogs are designer drugs which activate the serotonin 5-HT2 receptors.{21376,20771,21281} 4-chloro-2,5-Dimethoxyamphetamine (4-chloro-2,5-DMA) is an analog of 2,5-DMA which can be found on the illicit drug market.{20771} Its physiological and toxicological properties are poorly understood. This product is intended for research and forensic applications.
Brand:CaymanSKU:12038 - 5 mgAvailable on backorder
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4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate.{24622,54088,54089,54090,54091} It has been used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer compounds.{24622,54088,54089} It is also a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib (Item No. 10483), with antiproliferative activity.{54090,54091}
Brand:CaymanSKU:30487 - 100 mgAvailable on backorder
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4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate.{24622,54088,54089,54090,54091} It has been used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer compounds.{24622,54088,54089} It is also a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib (Item No. 10483), with antiproliferative activity.{54090,54091}
Brand:CaymanSKU:30487 - 25 mgAvailable on backorder
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4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate.{24622,54088,54089,54090,54091} It has been used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer compounds.{24622,54088,54089} It is also a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib (Item No. 10483), with antiproliferative activity.{54090,54091}
Brand:CaymanSKU:30487 - 250 mgAvailable on backorder
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4-Chloro-6,7-bis(2-methoxyethoxy)quinazoline is a building block and synthetic intermediate.{24622,54088,54089,54090,54091} It has been used as a precursor in the synthesis of receptor tyrosine kinase (RTK) inhibitors, dual RTK and histone deacetylase (HDAC) inhibitors, and anticancer compounds.{24622,54088,54089} It is also a synthetic intermediate in the synthesis of EGFR inhibitors, including erlotinib (Item No. 10483), with antiproliferative activity.{54090,54091}
Brand:CaymanSKU:30487 - 50 mgAvailable on backorder
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4-chloro-α-cyanocinnamic acid (Cl-CCA) is a phenylpropanoid, related to cinnamic acid, which is synthesized by plants from phenylalanine. Cl-CCA readily co-crystallizes with various biomolecules (e.g., peptides, nucleic acids, etc.).
Brand:CaymanSKU:9000981 - 10 mgAvailable on backorder
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4-chloro-α-cyanocinnamic acid (Cl-CCA) is a phenylpropanoid, related to cinnamic acid, which is synthesized by plants from phenylalanine. Cl-CCA readily co-crystallizes with various biomolecules (e.g., peptides, nucleic acids, etc.).
Brand:CaymanSKU:9000981 - 25 mgAvailable on backorder
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4-chloro-α-cyanocinnamic acid (Cl-CCA) is a phenylpropanoid, related to cinnamic acid, which is synthesized by plants from phenylalanine. Cl-CCA readily co-crystallizes with various biomolecules (e.g., peptides, nucleic acids, etc.).
Brand:CaymanSKU:9000981 - 5 mgAvailable on backorder
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4-chloro-α-cyanocinnamic acid (Cl-CCA) is a phenylpropanoid, related to cinnamic acid, which is synthesized by plants from phenylalanine. Cl-CCA readily co-crystallizes with various biomolecules (e.g., peptides, nucleic acids, etc.).
Brand:CaymanSKU:9000981 - 50 mgAvailable on backorder
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Halogenated amphetamines, including chloroamphetamines (CAs), are psychostimulatory compounds that have been abused recreationally.{25534} 4-CA is a halogenated amphetamine that causes rapid depletion of serotonin and its major metabolite, 5-hydroxyindoleacetic acid, in animal brains within hours after injection.{25537,25538} In addition, it is highly and selectively neurotoxic, targeting serotonergic neurons.{25537,25538} This product is intended for forensic and research applications.
Brand:CaymanSKU:9001856 - 10 mgAvailable on backorder
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Halogenated amphetamines, including chloroamphetamines (CAs), are psychostimulatory compounds that have been abused recreationally.{25534} 4-CA is a halogenated amphetamine that causes rapid depletion of serotonin and its major metabolite, 5-hydroxyindoleacetic acid, in animal brains within hours after injection.{25537,25538} In addition, it is highly and selectively neurotoxic, targeting serotonergic neurons.{25537,25538} This product is intended for forensic and research applications.
Brand:CaymanSKU:9001856 - 5 mgAvailable on backorder
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Halogenated amphetamines, including chloroamphetamines (CAs), are psychostimulatory compounds that have been abused recreationally.{25534} 4-CA is a halogenated amphetamine that causes rapid depletion of serotonin and its major metabolite, 5-hydroxyindoleacetic acid, in animal brains within hours after injection.{25537,25538} In addition, it is highly and selectively neurotoxic, targeting serotonergic neurons.{25537,25538} This product is intended for forensic and research applications.
Brand:CaymanSKU:9001856 - 50 mgAvailable on backorder
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4-Chlorocathinone (hydrochloride) (Item No. 30379) is an analytical reference standard categorized as a cathinone.{52427} 4-Chlorocathinone produces partial stimulus generalization to (±)-cathinone (Item Nos. 14138 | 15654) in rats. This product is intended for research and forensic applications.
Brand:CaymanSKU:30379 - 1 mgAvailable on backorder
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4-Chlorocathinone (hydrochloride) (Item No. 30379) is an analytical reference standard categorized as a cathinone.{52427} 4-Chlorocathinone produces partial stimulus generalization to (±)-cathinone (Item Nos. 14138 | 15654) in rats. This product is intended for research and forensic applications.
Brand:CaymanSKU:30379 - 5 mgAvailable on backorder
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Methamphetamine (Item No. 13997) is a regulated psychoactive compound that is both neurotoxic and prone to addiction.{26354,26355,26356} 4-Chloromethamphetamine is a halogenated analog of methamphetamine. In vivo, it is converted to 4-chloroamphetamine (Item No. 9001856), which causes rapid depletion of neurological serotonin within hours after injection.{25537,25538} 4-Chloroampetamine is highly and selectively neurotoxic, targeting serotonergic neurons.{25537,25538} This product is intended for forensic and research applications.
Brand:CaymanSKU:9002185 - 10 mgAvailable on backorder
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Methamphetamine (Item No. 13997) is a regulated psychoactive compound that is both neurotoxic and prone to addiction.{26354,26355,26356} 4-Chloromethamphetamine is a halogenated analog of methamphetamine. In vivo, it is converted to 4-chloroamphetamine (Item No. 9001856), which causes rapid depletion of neurological serotonin within hours after injection.{25537,25538} 4-Chloroampetamine is highly and selectively neurotoxic, targeting serotonergic neurons.{25537,25538} This product is intended for forensic and research applications.
Brand:CaymanSKU:9002185 - 5 mgAvailable on backorder
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Methamphetamine (Item No. 13997) is a regulated psychoactive compound that is both neurotoxic and prone to addiction.{26354,26355,26356} 4-Chloromethamphetamine is a halogenated analog of methamphetamine. In vivo, it is converted to 4-chloroamphetamine (Item No. 9001856), which causes rapid depletion of neurological serotonin within hours after injection.{25537,25538} 4-Chloroampetamine is highly and selectively neurotoxic, targeting serotonergic neurons.{25537,25538} This product is intended for forensic and research applications.
Brand:CaymanSKU:9002185 - 50 mgAvailable on backorder
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4-Chlorophenyl-2-pyridinylmethanol is a synthetic intermediate. It has been used in the synthesis of pharmaceutical compounds, including bepotastine besilate, a non-sedating antihistamine.{34017}
Brand:CaymanSKU:21861 -Out of stock
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4-Chlorophenyl-2-pyridinylmethanol is a synthetic intermediate. It has been used in the synthesis of pharmaceutical compounds, including bepotastine besilate, a non-sedating antihistamine.{34017}
Brand:CaymanSKU:21861 -Out of stock
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4-Chlorophenyl-2-pyridinylmethanol is a synthetic intermediate. It has been used in the synthesis of pharmaceutical compounds, including bepotastine besilate, a non-sedating antihistamine.{34017}
Brand:CaymanSKU:21861 -Out of stock
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4-Chlorophenyl-2-pyridinylmethanol is a synthetic intermediate. It has been used in the synthesis of pharmaceutical compounds, including bepotastine besilate, a non-sedating antihistamine.{34017}
Brand:CaymanSKU:21861 -Out of stock
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4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50 = 27 µM).{46807} It is selective for MIF-2 over MIF-1 (IC50 = 450 µM). It inhibits MIF-2, but not MIF-1, binding to CD74 in vitro when used at a concentration of 10 µM. 4-CPPC (5, 10, and 25 µM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
Brand:CaymanSKU:30068 - 1 mgAvailable on backorder
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4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50 = 27 µM).{46807} It is selective for MIF-2 over MIF-1 (IC50 = 450 µM). It inhibits MIF-2, but not MIF-1, binding to CD74 in vitro when used at a concentration of 10 µM. 4-CPPC (5, 10, and 25 µM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
Brand:CaymanSKU:30068 - 10 mgAvailable on backorder
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4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50 = 27 µM).{46807} It is selective for MIF-2 over MIF-1 (IC50 = 450 µM). It inhibits MIF-2, but not MIF-1, binding to CD74 in vitro when used at a concentration of 10 µM. 4-CPPC (5, 10, and 25 µM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
Brand:CaymanSKU:30068 - 5 mgAvailable on backorder
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4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50 = 27 µM).{46807} It is selective for MIF-2 over MIF-1 (IC50 = 450 µM). It inhibits MIF-2, but not MIF-1, binding to CD74 in vitro when used at a concentration of 10 µM. 4-CPPC (5, 10, and 25 µM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
Brand:CaymanSKU:30068 - 500 µgAvailable on backorder
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4-cyano MDMB-BUTINACA (Item No. 26507) is an analytical reference standard categorized as a synthetic cannabinoid.{22072} This product is intended for research and forensic applications.
Brand:CaymanSKU:26507 - 1 mgAvailable on backorder
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4-cyano MDMB-BUTINACA (Item No. 26507) is an analytical reference standard categorized as a synthetic cannabinoid.{22072} This product is intended for research and forensic applications.
Brand:CaymanSKU:26507 - 5 mgAvailable on backorder
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Brand:CaymanSKU:10007084 - 1 g
Available on backorder
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Brand:CaymanSKU:10007084 - 10 g
Available on backorder
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Brand:CaymanSKU:10007084 - 5 g
Available on backorder
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Brand:CaymanSKU:10007084 - 500 mg
Available on backorder
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4-DAMP is a potent antagonist of the muscarinic M3 receptor (pKi = 9.3).{23026,23027,23044} It is routinely used to study the regulation and functions of the M3 receptor.{23024,23023} 4-DAMP also has a high affinity for the closely-related M5 receptor (pKi = 8.9).{23044}
Brand:CaymanSKU:- -
4-DAMP is a potent antagonist of the muscarinic M3 receptor (pKi = 9.3).{23026,23027,23044} It is routinely used to study the regulation and functions of the M3 receptor.{23024,23023} 4-DAMP also has a high affinity for the closely-related M5 receptor (pKi = 8.9).{23044}
Brand:CaymanSKU:- -
4-DAMP is a potent antagonist of the muscarinic M3 receptor (pKi = 9.3).{23026,23027,23044} It is routinely used to study the regulation and functions of the M3 receptor.{23024,23023} 4-DAMP also has a high affinity for the closely-related M5 receptor (pKi = 8.9).{23044}
Brand:CaymanSKU:- -
4-deoxy Nivalenol is a natural type B trichothecene produced by certain species of the fungus Fusarium, particularly those found on cereal crops, including wheat, barley, oats, maize, and rye.{24416,24414} This mycotoxin can induce vomiting, diarrhea, and weight loss as well as other physiological and toxicological effects.{24415} It inhibits protein biosynthesis, binds to peptidyl transferase, and inhibits the synthesis of RNA and DNA, contributing to immunotoxicity.{24417} It passes the blood-brain barrier at different rates in different animals and this may be related to anorexia.{24415}
Brand:CaymanSKU:11428 - 1 mgAvailable on backorder
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4-deoxy Nivalenol is a natural type B trichothecene produced by certain species of the fungus Fusarium, particularly those found on cereal crops, including wheat, barley, oats, maize, and rye.{24416,24414} This mycotoxin can induce vomiting, diarrhea, and weight loss as well as other physiological and toxicological effects.{24415} It inhibits protein biosynthesis, binds to peptidyl transferase, and inhibits the synthesis of RNA and DNA, contributing to immunotoxicity.{24417} It passes the blood-brain barrier at different rates in different animals and this may be related to anorexia.{24415}
Brand:CaymanSKU:11428 - 5 mgAvailable on backorder
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4-deoxy Nivalenol is a natural type B trichothecene produced by certain species of the fungus Fusarium, particularly those found on cereal crops, including wheat, barley, oats, maize, and rye.{24416,24414} This mycotoxin can induce vomiting, diarrhea, and weight loss as well as other physiological and toxicological effects.{24415} It inhibits protein biosynthesis, binds to peptidyl transferase, and inhibits the synthesis of RNA and DNA, contributing to immunotoxicity.{24417} It passes the blood-brain barrier at different rates in different animals and this may be related to anorexia.{24415}
Brand:CaymanSKU:11428 - 500 µgAvailable on backorder
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4-deoxy Nivalenol-13C15 is intended for use as an internal standard for the quantification of 4-deoxy nivalenol (Item No. 11428) by GC- or LC-MS. 4-deoxy Nivalenol is a trichothecene mycotoxin that has been found in Fusarium.{24416} It binds to eukaryotic ribosomes and inhibits protein synthesis in mice when administered at doses ranging from 5 to 25 mg/kg. 4-deoxy Nivalenol (0.1 and 0.2 mg/kg) induces emesis in pigs and decreases feed consumption in pigs when administered at a dose of 40 ppb in the diet.{58158} It induces lethality in mice (LD50 = 46-78 mg/kg).{58159} 4-deoxy Nivalenol has been found in F. graminearum-infected cereal grains such as wheat, barley, and corn.
Brand:CaymanSKU:31249 - 1.2 mlAvailable on backorder
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4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities.{38612,38613,38614,38615,38616} It inhibits transport of pyridoxine (Item No. 20706), pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells.{38612} DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells.{38613} DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos.{38614} It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy.{38615} DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.{38616}
Brand:CaymanSKU:21863 -Out of stock
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4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities.{38612,38613,38614,38615,38616} It inhibits transport of pyridoxine (Item No. 20706), pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells.{38612} DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells.{38613} DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos.{38614} It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy.{38615} DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.{38616}
Brand:CaymanSKU:21863 -Out of stock
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4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities.{38612,38613,38614,38615,38616} It inhibits transport of pyridoxine (Item No. 20706), pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells.{38612} DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells.{38613} DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos.{38614} It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy.{38615} DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.{38616}
Brand:CaymanSKU:21863 -Out of stock
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4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities.{38612,38613,38614,38615,38616} It inhibits transport of pyridoxine (Item No. 20706), pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells.{38612} DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells.{38613} DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos.{38614} It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy.{38615} DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.{38616}
Brand:CaymanSKU:21863 -Out of stock
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4-deoxy-4α-Phorbol is a tetracyclic diterpene found in croton oil.{39635,39636} It has been used in the semisynthesis of inhibitors of the HIV-1-induced cytopathic effect on MT-4 cells and 4α-phorbol esters.
Brand:CaymanSKU:24998 - 1 mgAvailable on backorder
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4-deoxy-4α-Phorbol is a tetracyclic diterpene found in croton oil.{39635,39636} It has been used in the semisynthesis of inhibitors of the HIV-1-induced cytopathic effect on MT-4 cells and 4α-phorbol esters.
Brand:CaymanSKU:24998 - 10 mgAvailable on backorder
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4-deoxy-4α-Phorbol is a tetracyclic diterpene found in croton oil.{39635,39636} It has been used in the semisynthesis of inhibitors of the HIV-1-induced cytopathic effect on MT-4 cells and 4α-phorbol esters.
Brand:CaymanSKU:24998 - 25 mgAvailable on backorder
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4-deoxy-4α-Phorbol is a tetracyclic diterpene found in croton oil.{39635,39636} It has been used in the semisynthesis of inhibitors of the HIV-1-induced cytopathic effect on MT-4 cells and 4α-phorbol esters.
Brand:CaymanSKU:24998 - 5 mgAvailable on backorder
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4-Deoxypyridoxine phosphate is a vitamin B6 analog and an inhibitor of sphingosine-1-phosphate (S1P) lyase.{50834} It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50s = 100 µM in the absence and presence of vitamin B6, respectively).
Brand:CaymanSKU:29973 - 1 mgAvailable on backorder
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4-Deoxypyridoxine phosphate is a vitamin B6 analog and an inhibitor of sphingosine-1-phosphate (S1P) lyase.{50834} It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50s = 100 µM in the absence and presence of vitamin B6, respectively).
Brand:CaymanSKU:29973 - 10 mgAvailable on backorder
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4-Deoxypyridoxine phosphate is a vitamin B6 analog and an inhibitor of sphingosine-1-phosphate (S1P) lyase.{50834} It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50s = 100 µM in the absence and presence of vitamin B6, respectively).
Brand:CaymanSKU:29973 - 25 mgAvailable on backorder
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4-Deoxypyridoxine phosphate is a vitamin B6 analog and an inhibitor of sphingosine-1-phosphate (S1P) lyase.{50834} It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50s = 100 µM in the absence and presence of vitamin B6, respectively).
Brand:CaymanSKU:29973 - 5 mgAvailable on backorder
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4-desmethoxy Omeprazole is a potential impurity found in commercial omeprazole and esomeprazole magnesium preparations. Omeprazole (Item No. 14880) is a selective and irreversible inhibitor of the gastric H+/K+ ATPase pump (IC50 = 1.1 μM).{14045} It is a racemic mixture of two enantiomers, (S)-omeprazole (esomeprazole magnesium; Item No. 17326) and (R)-omeprazole (Item No. 18874), which are prodrugs of the active sulfonamide which is formed by acid-stimulated conversion.{18256,18249} Both enantiomers are extensively metabolized by the cytochrome P450 (CYP) isomers CYP2C19 and CYP3A4.{18249}
Brand:CaymanSKU:22122 -Out of stock
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4-desmethoxy Omeprazole is a potential impurity found in commercial omeprazole and esomeprazole magnesium preparations. Omeprazole (Item No. 14880) is a selective and irreversible inhibitor of the gastric H+/K+ ATPase pump (IC50 = 1.1 μM).{14045} It is a racemic mixture of two enantiomers, (S)-omeprazole (esomeprazole magnesium; Item No. 17326) and (R)-omeprazole (Item No. 18874), which are prodrugs of the active sulfonamide which is formed by acid-stimulated conversion.{18256,18249} Both enantiomers are extensively metabolized by the cytochrome P450 (CYP) isomers CYP2C19 and CYP3A4.{18249}
Brand:CaymanSKU:22122 -Out of stock
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4-desmethoxy Omeprazole is a potential impurity found in commercial omeprazole and esomeprazole magnesium preparations. Omeprazole (Item No. 14880) is a selective and irreversible inhibitor of the gastric H+/K+ ATPase pump (IC50 = 1.1 μM).{14045} It is a racemic mixture of two enantiomers, (S)-omeprazole (esomeprazole magnesium; Item No. 17326) and (R)-omeprazole (Item No. 18874), which are prodrugs of the active sulfonamide which is formed by acid-stimulated conversion.{18256,18249} Both enantiomers are extensively metabolized by the cytochrome P450 (CYP) isomers CYP2C19 and CYP3A4.{18249}
Brand:CaymanSKU:22122 -Out of stock
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4-desmethoxy Omeprazole is a potential impurity found in commercial omeprazole and esomeprazole magnesium preparations. Omeprazole (Item No. 14880) is a selective and irreversible inhibitor of the gastric H+/K+ ATPase pump (IC50 = 1.1 μM).{14045} It is a racemic mixture of two enantiomers, (S)-omeprazole (esomeprazole magnesium; Item No. 17326) and (R)-omeprazole (Item No. 18874), which are prodrugs of the active sulfonamide which is formed by acid-stimulated conversion.{18256,18249} Both enantiomers are extensively metabolized by the cytochrome P450 (CYP) isomers CYP2C19 and CYP3A4.{18249}
Brand:CaymanSKU:22122 -Out of stock
![A vitamin B6 analog and an inhibitor of S1P lyase; induces accumulation of [3H]dhS1P in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50s = 100 µM in the absence and presence of vitamin B6](https://interpriseusa.com/wp-content/uploads/2021/06/29973.png)
