Cayman
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3-methoxythio Benzamide is a synthetic intermediate useful for pharmaceutical synthesis. Thiobenzamides, including 3-methoxythio benzamide, are potent hepatotoxins in vivo.{18419}
Brand:CaymanSKU:10553 - 500 mgAvailable on backorder
Brand:CaymanSKU:13057 - 1 gAvailable on backorder
Brand:CaymanSKU:13057 - 5 gAvailable on backorder
Brand:CaymanSKU:13057 - 500 mgAvailable on backorder
3-methyl Orsellinic acid is a fungal metabolite that has been found in A. terreus.{41780} It has been used as a standard in dereplication of natural products.{41781}
Brand:CaymanSKU:25113 - 25 mgAvailable on backorder
3-methyl Orsellinic acid is a fungal metabolite that has been found in A. terreus.{41780} It has been used as a standard in dereplication of natural products.{41781}
Brand:CaymanSKU:25113 - 5 mgAvailable on backorder
Brand:CaymanSKU:13006 - 1 gAvailable on backorder
Brand:CaymanSKU:13006 - 250 mgAvailable on backorder
Brand:CaymanSKU:13006 - 5 gAvailable on backorder
Brand:CaymanSKU:13006 - 500 mgAvailable on backorder
3-Methyl-L-histidine is an endogenous amino acid and a component of the skeletal muscle proteins actin and myosin.{57085,57086,57087} It is released during the catabolism of muscle fibrillar protein and excreted in urine.{57087} Urinary levels of 3-methyl-L-histidine are decreased in children with protein-energy malnutrition compared with well-nourished control subjects. 3-Methyl-L-histidine has been used as a biomarker of skeletal muscle catabolism.{57085,57086,57087}
Brand:CaymanSKU:31165 - 100 mgAvailable on backorder
3-Methyl-L-histidine is an endogenous amino acid and a component of the skeletal muscle proteins actin and myosin.{57085,57086,57087} It is released during the catabolism of muscle fibrillar protein and excreted in urine.{57087} Urinary levels of 3-methyl-L-histidine are decreased in children with protein-energy malnutrition compared with well-nourished control subjects. 3-Methyl-L-histidine has been used as a biomarker of skeletal muscle catabolism.{57085,57086,57087}
Brand:CaymanSKU:31165 - 50 mgAvailable on backorder
Autophagy is a multi-step process that involves the degradation and digestion of intracellular components by the lysosome. This process allows cells to efficiently mobilize and recycle cellular constituents, and also prevents the accumulation of damaged organelles, misfolded proteins, and invading microorganisms. mTOR, whose activation is controlled by phosphoinositide 3-kinase (PI3K), is a key regulator of autophagy.{20297} 3-Methyladenine (3-MA) is a specific inhibitor of PI3K activity and one of the most widely used inhibitors of the initial phase of the autophagic process: the sequestering of cytoplasmic material by the lysosome.{21363,21361} At 5 mM, 3-MA inhibits protein degradation in rat hepatocytes by 65%.{21363} 3-MA has been shown to block class I, class II, and class III PI3Ks, including some downstream targets, and to suppress the invasion of highly metastatic human fibrosarcoma HT1080 cells at 10 mM.{21364,21362}
Brand:CaymanSKU:- Autophagy is a multi-step process that involves the degradation and digestion of intracellular components by the lysosome. This process allows cells to efficiently mobilize and recycle cellular constituents, and also prevents the accumulation of damaged organelles, misfolded proteins, and invading microorganisms. mTOR, whose activation is controlled by phosphoinositide 3-kinase (PI3K), is a key regulator of autophagy.{20297} 3-Methyladenine (3-MA) is a specific inhibitor of PI3K activity and one of the most widely used inhibitors of the initial phase of the autophagic process: the sequestering of cytoplasmic material by the lysosome.{21363,21361} At 5 mM, 3-MA inhibits protein degradation in rat hepatocytes by 65%.{21363} 3-MA has been shown to block class I, class II, and class III PI3Ks, including some downstream targets, and to suppress the invasion of highly metastatic human fibrosarcoma HT1080 cells at 10 mM.{21364,21362}
Brand:CaymanSKU:- Autophagy is a multi-step process that involves the degradation and digestion of intracellular components by the lysosome. This process allows cells to efficiently mobilize and recycle cellular constituents, and also prevents the accumulation of damaged organelles, misfolded proteins, and invading microorganisms. mTOR, whose activation is controlled by phosphoinositide 3-kinase (PI3K), is a key regulator of autophagy.{20297} 3-Methyladenine (3-MA) is a specific inhibitor of PI3K activity and one of the most widely used inhibitors of the initial phase of the autophagic process: the sequestering of cytoplasmic material by the lysosome.{21363,21361} At 5 mM, 3-MA inhibits protein degradation in rat hepatocytes by 65%.{21363} 3-MA has been shown to block class I, class II, and class III PI3Ks, including some downstream targets, and to suppress the invasion of highly metastatic human fibrosarcoma HT1080 cells at 10 mM.{21364,21362}
Brand:CaymanSKU:-
3-Methylcrotonyl glycine (3-MCG) is a metabolite found in the urine of patients with 3-methylcrotonyl glycinuria, a metabolic disorder characterized by a deficiency in 3-methylcrotonyl-CoA carboxylase, that has diverse biological activities.{36412,36413} It inhibits CO2 production and mitochondrial complex II-III and creatine kinase activity in rat cerebral cortex preparations in a concentration-dependent manner.{36413} It also inhibits the Na+/K+-ATPase in purified synaptic membranes from rat cerebrum, indicating a potential role for this metabolite in the development of CNS damage associated with 3-methycrotonyl glycinuria.
Brand:CaymanSKU:22888 - 10 mgAvailable on backorder
3-Methylcrotonyl glycine (3-MCG) is a metabolite found in the urine of patients with 3-methylcrotonyl glycinuria, a metabolic disorder characterized by a deficiency in 3-methylcrotonyl-CoA carboxylase, that has diverse biological activities.{36412,36413} It inhibits CO2 production and mitochondrial complex II-III and creatine kinase activity in rat cerebral cortex preparations in a concentration-dependent manner.{36413} It also inhibits the Na+/K+-ATPase in purified synaptic membranes from rat cerebrum, indicating a potential role for this metabolite in the development of CNS damage associated with 3-methycrotonyl glycinuria.
Brand:CaymanSKU:22888 - 100 mgAvailable on backorder
3-Methylcrotonyl glycine (3-MCG) is a metabolite found in the urine of patients with 3-methylcrotonyl glycinuria, a metabolic disorder characterized by a deficiency in 3-methylcrotonyl-CoA carboxylase, that has diverse biological activities.{36412,36413} It inhibits CO2 production and mitochondrial complex II-III and creatine kinase activity in rat cerebral cortex preparations in a concentration-dependent manner.{36413} It also inhibits the Na+/K+-ATPase in purified synaptic membranes from rat cerebrum, indicating a potential role for this metabolite in the development of CNS damage associated with 3-methycrotonyl glycinuria.
Brand:CaymanSKU:22888 - 250 mgAvailable on backorder
3-Methylcrotonyl glycine (3-MCG) is a metabolite found in the urine of patients with 3-methylcrotonyl glycinuria, a metabolic disorder characterized by a deficiency in 3-methylcrotonyl-CoA carboxylase, that has diverse biological activities.{36412,36413} It inhibits CO2 production and mitochondrial complex II-III and creatine kinase activity in rat cerebral cortex preparations in a concentration-dependent manner.{36413} It also inhibits the Na+/K+-ATPase in purified synaptic membranes from rat cerebrum, indicating a potential role for this metabolite in the development of CNS damage associated with 3-methycrotonyl glycinuria.
Brand:CaymanSKU:22888 - 50 mgAvailable on backorder
3-Methylcytidine (methosulfate) is a cytidine derivative used as an internal standard for HPLC. 3-Methylcytidine is a common epigenetic modification in tRNA but its role in the cell has not been defined.{34089} 3-Methylcytidine has been investigated as a potential biomarker for cancer and was significantly elevated in the urine of breast cancer patients.{27863}
Brand:CaymanSKU:21064 -Out of stock
3-Methylcytidine (methosulfate) is a cytidine derivative used as an internal standard for HPLC. 3-Methylcytidine is a common epigenetic modification in tRNA but its role in the cell has not been defined.{34089} 3-Methylcytidine has been investigated as a potential biomarker for cancer and was significantly elevated in the urine of breast cancer patients.{27863}
Brand:CaymanSKU:21064 -Out of stock
3-Methylcytidine (methosulfate) is a cytidine derivative used as an internal standard for HPLC. 3-Methylcytidine is a common epigenetic modification in tRNA but its role in the cell has not been defined.{34089} 3-Methylcytidine has been investigated as a potential biomarker for cancer and was significantly elevated in the urine of breast cancer patients.{27863}
Brand:CaymanSKU:21064 -Out of stock
4-Methylmethcathinone (4-methyl MC) is a psychoactive synthetic cathinone that has been identified in bath salts and powders.{19498,19193,19508} 3-Methylmethcathinone (3-methyl MC) (hydrochloride) is a potential major impurity in preparations of 4-methyl MC. As an isomer of 4-methyl MC, it is likely to have psychoactive properties and may itself be marketed as a designer drug. The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:11224 - 10 mgAvailable on backorder
4-Methylmethcathinone (4-methyl MC) is a psychoactive synthetic cathinone that has been identified in bath salts and powders.{19498,19193,19508} 3-Methylmethcathinone (3-methyl MC) (hydrochloride) is a potential major impurity in preparations of 4-methyl MC. As an isomer of 4-methyl MC, it is likely to have psychoactive properties and may itself be marketed as a designer drug. The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:11224 - 5 mgAvailable on backorder
4-Methylmethcathinone (4-methyl MC) is a psychoactive synthetic cathinone that has been identified in bath salts and powders.{19498,19193,19508} 3-Methylmethcathinone (3-methyl MC) (hydrochloride) is a potential major impurity in preparations of 4-methyl MC. As an isomer of 4-methyl MC, it is likely to have psychoactive properties and may itself be marketed as a designer drug. The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:11224 - 50 mgAvailable on backorder
3-Methylquinoxaline-2-carboxylic acid (MQCA) is a major metabolite of olaquindox, an antibiotic and swine growth regulator.{48040,48041} It induces cell cycle arrest at the S phase and is toxic to Chang liver cells in a concentration- and time-dependent manner.{48041} MQCA has been used as a marker of olaquindox use in livestock applications.{48040}
Brand:CaymanSKU:25664 - 10 mgAvailable on backorder
3-Methylquinoxaline-2-carboxylic acid (MQCA) is a major metabolite of olaquindox, an antibiotic and swine growth regulator.{48040,48041} It induces cell cycle arrest at the S phase and is toxic to Chang liver cells in a concentration- and time-dependent manner.{48041} MQCA has been used as a marker of olaquindox use in livestock applications.{48040}
Brand:CaymanSKU:25664 - 100 mgAvailable on backorder
3-Methylquinoxaline-2-carboxylic acid (MQCA) is a major metabolite of olaquindox, an antibiotic and swine growth regulator.{48040,48041} It induces cell cycle arrest at the S phase and is toxic to Chang liver cells in a concentration- and time-dependent manner.{48041} MQCA has been used as a marker of olaquindox use in livestock applications.{48040}
Brand:CaymanSKU:25664 - 5 mgAvailable on backorder
3-Methylquinoxaline-2-carboxylic acid (MQCA) is a major metabolite of olaquindox, an antibiotic and swine growth regulator.{48040,48041} It induces cell cycle arrest at the S phase and is toxic to Chang liver cells in a concentration- and time-dependent manner.{48041} MQCA has been used as a marker of olaquindox use in livestock applications.{48040}
Brand:CaymanSKU:25664 - 50 mgAvailable on backorder
3-Nitropropionic acid (3-NP) is an irreversible inhibitor of mitochondrial respiratory Complex II succinate dehydrogenase, resulting in energy depletion through disruption of the electron transport chain.{29416,29417,29415} This compound is a natural toxin of certain plants and fungi. Administration of 3-NP to rats (12 mg/kg per day) produces progressive striatal degeneration, while lower doses (8 mg/kg daily) in nonhuman primates results in neuropathologic and clinical features of Huntington’s disease.{29416} Conversely, Huntington’s disease results in a loss of Complex II activity.{29417} 3-NP also induces convulsions and is used to examine interventions effective in a mouse model of epilepsy.{29418}
Brand:CaymanSKU:- 3-Nitropropionic acid (3-NP) is an irreversible inhibitor of mitochondrial respiratory Complex II succinate dehydrogenase, resulting in energy depletion through disruption of the electron transport chain.{29416,29417,29415} This compound is a natural toxin of certain plants and fungi. Administration of 3-NP to rats (12 mg/kg per day) produces progressive striatal degeneration, while lower doses (8 mg/kg daily) in nonhuman primates results in neuropathologic and clinical features of Huntington’s disease.{29416} Conversely, Huntington’s disease results in a loss of Complex II activity.{29417} 3-NP also induces convulsions and is used to examine interventions effective in a mouse model of epilepsy.{29418}
Brand:CaymanSKU:- 3-Nitropropionic acid (3-NP) is an irreversible inhibitor of mitochondrial respiratory Complex II succinate dehydrogenase, resulting in energy depletion through disruption of the electron transport chain.{29416,29417,29415} This compound is a natural toxin of certain plants and fungi. Administration of 3-NP to rats (12 mg/kg per day) produces progressive striatal degeneration, while lower doses (8 mg/kg daily) in nonhuman primates results in neuropathologic and clinical features of Huntington’s disease.{29416} Conversely, Huntington’s disease results in a loss of Complex II activity.{29417} 3-NP also induces convulsions and is used to examine interventions effective in a mouse model of epilepsy.{29418}
Brand:CaymanSKU:-
3-O-methyl-L-DOPA is a metabolite of L-DOPA (Item No. 13248), produced by the activity of catechol O-methyltransferase. 3-O-methyl-L-DOPA may have effects of its own or it may compete with the actions of L-DOPA.{32397,32398,32399}
Brand:CaymanSKU:20737 -Available on backorder
3-O-methyl-L-DOPA is a metabolite of L-DOPA (Item No. 13248), produced by the activity of catechol O-methyltransferase. 3-O-methyl-L-DOPA may have effects of its own or it may compete with the actions of L-DOPA.{32397,32398,32399}
Brand:CaymanSKU:20737 -Available on backorder
3-O-methyl-L-DOPA is a metabolite of L-DOPA (Item No. 13248), produced by the activity of catechol O-methyltransferase. 3-O-methyl-L-DOPA may have effects of its own or it may compete with the actions of L-DOPA.{32397,32398,32399}
Brand:CaymanSKU:20737 -Available on backorder
3-O-methyl-L-DOPA is a metabolite of L-DOPA (Item No. 13248), produced by the activity of catechol O-methyltransferase. 3-O-methyl-L-DOPA may have effects of its own or it may compete with the actions of L-DOPA.{32397,32398,32399}
Brand:CaymanSKU:20737 -Available on backorder
3-O-methyl-N-acetyl-D-Glucosamine (3-O-methyl-GlcNAc) is a competitive inhibitor of N-acetylglucosamine kinase and a non-competitive inhibitor of N-acetylmannosamine kinase (Kis = 17 and 80 µM in rat liver, respectively, in vitro).{34408}
Brand:CaymanSKU:10011056 - 1 mgAvailable on backorder
3-O-methyl-N-acetyl-D-Glucosamine (3-O-methyl-GlcNAc) is a competitive inhibitor of N-acetylglucosamine kinase and a non-competitive inhibitor of N-acetylmannosamine kinase (Kis = 17 and 80 µM in rat liver, respectively, in vitro).{34408}
Brand:CaymanSKU:10011056 - 10 mgAvailable on backorder
3-O-methyl-N-acetyl-D-Glucosamine (3-O-methyl-GlcNAc) is a competitive inhibitor of N-acetylglucosamine kinase and a non-competitive inhibitor of N-acetylmannosamine kinase (Kis = 17 and 80 µM in rat liver, respectively, in vitro).{34408}
Brand:CaymanSKU:10011056 - 5 mgAvailable on backorder
3-oxo Stearic acid is an intermediate in the dissociated (or type II) fatty acid biosynthesis that occurs in bacteria and plants.{25141} This β-keto fatty acid is generated following the reaction of hexadecenoyl-acyl-carrier-protein (ACP) with malonyl-ACP by the enzyme β-ketoacyl-ACP synthase II, which produces 3-oxo octadecenoyl-ACP.{25140} Removal of the ACP group by ACP hydrolase produces the free acid.
Brand:CaymanSKU:- 3-oxo Stearic acid is an intermediate in the dissociated (or type II) fatty acid biosynthesis that occurs in bacteria and plants.{25141} This β-keto fatty acid is generated following the reaction of hexadecenoyl-acyl-carrier-protein (ACP) with malonyl-ACP by the enzyme β-ketoacyl-ACP synthase II, which produces 3-oxo octadecenoyl-ACP.{25140} Removal of the ACP group by ACP hydrolase produces the free acid.
Brand:CaymanSKU:- 3-oxo Stearic acid is an intermediate in the dissociated (or type II) fatty acid biosynthesis that occurs in bacteria and plants.{25141} This β-keto fatty acid is generated following the reaction of hexadecenoyl-acyl-carrier-protein (ACP) with malonyl-ACP by the enzyme β-ketoacyl-ACP synthase II, which produces 3-oxo octadecenoyl-ACP.{25140} Removal of the ACP group by ACP hydrolase produces the free acid.
Brand:CaymanSKU:-
3-Oxocholic acid is a secondary bile acid and a metabolite of cholic acid (Item No. 20250) in C. perfringens, a bacteria found in the intestines of mammals and in the environment.{45190,51216} 3-Oxocholic acid serum levels increase following ileal transposition surgery in rats.{51217}
Brand:CaymanSKU:28403 - 100 mgAvailable on backorder
3-Oxocholic acid is a secondary bile acid and a metabolite of cholic acid (Item No. 20250) in C. perfringens, a bacteria found in the intestines of mammals and in the environment.{45190,51216} 3-Oxocholic acid serum levels increase following ileal transposition surgery in rats.{51217}
Brand:CaymanSKU:28403 - 25 mgAvailable on backorder
3-Oxocholic acid is a secondary bile acid and a metabolite of cholic acid (Item No. 20250) in C. perfringens, a bacteria found in the intestines of mammals and in the environment.{45190,51216} 3-Oxocholic acid serum levels increase following ileal transposition surgery in rats.{51217}
Brand:CaymanSKU:28403 - 250 mgAvailable on backorder
3-Oxocholic acid is a secondary bile acid and a metabolite of cholic acid (Item No. 20250) in C. perfringens, a bacteria found in the intestines of mammals and in the environment.{45190,51216} 3-Oxocholic acid serum levels increase following ileal transposition surgery in rats.{51217}
Brand:CaymanSKU:28403 - 50 mgAvailable on backorder
3-Propylxanthine is a xanthine derivative that antagonizes adenosine receptors (Kis = 44, 32, and 6.3 µM for A1, A2A, and A2B, respectively) and cAMP phosphodiesterase (Ki = 42 µM).{27926,33858,29142} Through these actions, 3-propylxanthine induces smooth muscle relaxation, blocks smooth muscle contraction and VEGF secretion driven by adenosine receptor agonists, and reduces bronchial hyperresponsiveness.{33856,33857,33858}
Brand:CaymanSKU:21746 -Out of stock
3-Propylxanthine is a xanthine derivative that antagonizes adenosine receptors (Kis = 44, 32, and 6.3 µM for A1, A2A, and A2B, respectively) and cAMP phosphodiesterase (Ki = 42 µM).{27926,33858,29142} Through these actions, 3-propylxanthine induces smooth muscle relaxation, blocks smooth muscle contraction and VEGF secretion driven by adenosine receptor agonists, and reduces bronchial hyperresponsiveness.{33856,33857,33858}
Brand:CaymanSKU:21746 -Out of stock
3-Propylxanthine is a xanthine derivative that antagonizes adenosine receptors (Kis = 44, 32, and 6.3 µM for A1, A2A, and A2B, respectively) and cAMP phosphodiesterase (Ki = 42 µM).{27926,33858,29142} Through these actions, 3-propylxanthine induces smooth muscle relaxation, blocks smooth muscle contraction and VEGF secretion driven by adenosine receptor agonists, and reduces bronchial hyperresponsiveness.{33856,33857,33858}
Brand:CaymanSKU:21746 -Out of stock
Brand:CaymanSKU:13004 - 1 gAvailable on backorder
Brand:CaymanSKU:13004 - 100 mgAvailable on backorder
Brand:CaymanSKU:13004 - 250 mgAvailable on backorder
Brand:CaymanSKU:13004 - 500 mgAvailable on backorder
3-Pyrimidin-2-yl-2-pyrimidin-2-ylmethyl-propionic acid is a synthetic intermediate useful for pharmaceutical synthesis.
Brand:CaymanSKU:10007110 - 1 gAvailable on backorder
3-Pyrimidin-2-yl-2-pyrimidin-2-ylmethyl-propionic acid is a synthetic intermediate useful for pharmaceutical synthesis.
Brand:CaymanSKU:10007110 - 100 mgAvailable on backorder
3-Pyrimidin-2-yl-2-pyrimidin-2-ylmethyl-propionic acid is a synthetic intermediate useful for pharmaceutical synthesis.
Brand:CaymanSKU:10007110 - 500 mgAvailable on backorder
Brand:CaymanSKU:10007109 - 1 gAvailable on backorder
Brand:CaymanSKU:10007109 - 100 mgAvailable on backorder
Brand:CaymanSKU:10007109 - 50 mgAvailable on backorder
Brand:CaymanSKU:10007109 - 500 mgAvailable on backorder
3-Thiatetradecanoic acid (3-thia TDA) is an analog of the 14-carbon saturated fatty acid myristic acid, wherein the C-3 carbon has been replaced by sulfur in a thioether linkage. When chronically administered to rats, 3-thia TDA acts as a peroxisome inducer (PPAR ligand), increases fatty acid oxidation, and lowers plasma lipid levels.{3828} Incorporation of 3-thia TDA into dietary regimens at 150 and 300 mg/kg in rats induces the formation of oleic acid via Δ9-desaturase, and dose-dependently increases Δ9-desaturase mRNA levels.{4942}
Brand:CaymanSKU:90500 - 1 mgAvailable on backorder
3-Thiatetradecanoic acid (3-thia TDA) is an analog of the 14-carbon saturated fatty acid myristic acid, wherein the C-3 carbon has been replaced by sulfur in a thioether linkage. When chronically administered to rats, 3-thia TDA acts as a peroxisome inducer (PPAR ligand), increases fatty acid oxidation, and lowers plasma lipid levels.{3828} Incorporation of 3-thia TDA into dietary regimens at 150 and 300 mg/kg in rats induces the formation of oleic acid via Δ9-desaturase, and dose-dependently increases Δ9-desaturase mRNA levels.{4942}
Brand:CaymanSKU:90500 - 10 mgAvailable on backorder
3-Thiatetradecanoic acid (3-thia TDA) is an analog of the 14-carbon saturated fatty acid myristic acid, wherein the C-3 carbon has been replaced by sulfur in a thioether linkage. When chronically administered to rats, 3-thia TDA acts as a peroxisome inducer (PPAR ligand), increases fatty acid oxidation, and lowers plasma lipid levels.{3828} Incorporation of 3-thia TDA into dietary regimens at 150 and 300 mg/kg in rats induces the formation of oleic acid via Δ9-desaturase, and dose-dependently increases Δ9-desaturase mRNA levels.{4942}
Brand:CaymanSKU:90500 - 5 mgAvailable on backorder
Brand:CaymanSKU:10007103 - 1 gAvailable on backorder
Brand:CaymanSKU:10007103 - 10 gAvailable on backorder
Brand:CaymanSKU:10007103 - 25 gAvailable on backorder
Brand:CaymanSKU:10007103 - 5 gAvailable on backorder
3-Thiopheneacrylic acid methyl ester is a synthetic intermediate useful for pharmaceutical synthesis.
Brand:CaymanSKU:10007102 - 1 gAvailable on backorder
3-Thiopheneacrylic acid methyl ester is a synthetic intermediate useful for pharmaceutical synthesis.
Brand:CaymanSKU:10007102 - 10 gAvailable on backorder
3-Thiopheneacrylic acid methyl ester is a synthetic intermediate useful for pharmaceutical synthesis.
Brand:CaymanSKU:10007102 - 25 gAvailable on backorder
3-Thiopheneacrylic acid methyl ester is a synthetic intermediate useful for pharmaceutical synthesis.
Brand:CaymanSKU:10007102 - 5 gAvailable on backorder
3-trifluoromethyl-N-Methylamphetamine (Item No. 22492) is an analytical reference standard that is categorized as an amphetamine. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Brand:CaymanSKU:22492 -Out of stock
3-trifluoromethyl-N-Methylamphetamine (Item No. 22492) is an analytical reference standard that is categorized as an amphetamine. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Brand:CaymanSKU:22492 -Out of stock
3-Trifluoromethylamphetamine (hydrochloride) ( Item No. 22604) is an analytical reference standard that is categorized as an amphetamine. It is an active metabolite of fenfluramine and benfluorex that acts as an agonist at serotonin (5-HT) receptors (IC50s = 6.92, 3.55, 0.17, and 2.09 µM for 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT2 receptors, respectively, in murine brain).{39006,39005} Norfenfluramine induces anorexia in mice and rats with EC50 values of 6.8 and 0.8 mg/kg, i.p., respectively.{39006} This product is intended for research and forensic applications.
Brand:CaymanSKU:22604 -Out of stock
3-Trifluoromethylamphetamine (hydrochloride) ( Item No. 22604) is an analytical reference standard that is categorized as an amphetamine. It is an active metabolite of fenfluramine and benfluorex that acts as an agonist at serotonin (5-HT) receptors (IC50s = 6.92, 3.55, 0.17, and 2.09 µM for 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT2 receptors, respectively, in murine brain).{39006,39005} Norfenfluramine induces anorexia in mice and rats with EC50 values of 6.8 and 0.8 mg/kg, i.p., respectively.{39006} This product is intended for research and forensic applications.
Brand:CaymanSKU:22604 -Out of stock
3-TYP is a sirtuin 3 (SIRT3) inhibitor (IC50 = 38 μM).{48840} It is selective for SIRT3 over SIRT1 and SIRT2 at 1 mM. 3-TYP (1 mM) increases acetylation of lysine residues in mitochondrial proteins in HeLa cells. It inhibits the growth of CCRF-CEM, COLO 205, OVCAR-4, OVCAR-8, and SKOV3 cells by greater than 50% when used at a concentration of 10 μM.
Brand:CaymanSKU:29660 - 1 gAvailable on backorder
3-TYP is a sirtuin 3 (SIRT3) inhibitor (IC50 = 38 μM).{48840} It is selective for SIRT3 over SIRT1 and SIRT2 at 1 mM. 3-TYP (1 mM) increases acetylation of lysine residues in mitochondrial proteins in HeLa cells. It inhibits the growth of CCRF-CEM, COLO 205, OVCAR-4, OVCAR-8, and SKOV3 cells by greater than 50% when used at a concentration of 10 μM.
Brand:CaymanSKU:29660 - 100 mgAvailable on backorder
3-TYP is a sirtuin 3 (SIRT3) inhibitor (IC50 = 38 μM).{48840} It is selective for SIRT3 over SIRT1 and SIRT2 at 1 mM. 3-TYP (1 mM) increases acetylation of lysine residues in mitochondrial proteins in HeLa cells. It inhibits the growth of CCRF-CEM, COLO 205, OVCAR-4, OVCAR-8, and SKOV3 cells by greater than 50% when used at a concentration of 10 μM.
Brand:CaymanSKU:29660 - 250 mgAvailable on backorder
3-TYP is a sirtuin 3 (SIRT3) inhibitor (IC50 = 38 μM).{48840} It is selective for SIRT3 over SIRT1 and SIRT2 at 1 mM. 3-TYP (1 mM) increases acetylation of lysine residues in mitochondrial proteins in HeLa cells. It inhibits the growth of CCRF-CEM, COLO 205, OVCAR-4, OVCAR-8, and SKOV3 cells by greater than 50% when used at a concentration of 10 μM.
Brand:CaymanSKU:29660 - 500 mgAvailable on backorder
3,3′-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) is a non-nucleotide inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; Ki = 50 µM).{48700,50816} It also inhibits urease (IC50 = 84.53 µM for the Jack bean enzyme).{48701}
Brand:CaymanSKU:29864 - 1 mgAvailable on backorder
3,3′-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) is a non-nucleotide inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; Ki = 50 µM).{48700,50816} It also inhibits urease (IC50 = 84.53 µM for the Jack bean enzyme).{48701}
Brand:CaymanSKU:29864 - 10 mgAvailable on backorder