Cayman
Showing 4501–4650 of 45550 results
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Brand:CaymanSKU:- Brand:CaymanSKU:- Brand:CaymanSKU:- Brand:CaymanSKU:-
2-methyl-4′-(methylthio)-2-Morpholinopropiophenone (MMMP; Item No. 21651) is an analytical reference standard that is structurally characterized as a substituted cathinone. It is a photoinitiator that almost instantaneously generates free radicals to induce polymerization in the production of UV curable inks, to speed drying during printing, and in colored coatings.{33785} MMMP is toxic to human peripheral blood mononuclear cells in vitro (250 µg/ml) through a caspase 3/7-dependent mechanism.{33786} This product is intended for research and forensic applications.
Brand:CaymanSKU:21651 -Out of stock
2-methyl-4′-(methylthio)-2-Morpholinopropiophenone (MMMP; Item No. 21651) is an analytical reference standard that is structurally characterized as a substituted cathinone. It is a photoinitiator that almost instantaneously generates free radicals to induce polymerization in the production of UV curable inks, to speed drying during printing, and in colored coatings.{33785} MMMP is toxic to human peripheral blood mononuclear cells in vitro (250 µg/ml) through a caspase 3/7-dependent mechanism.{33786} This product is intended for research and forensic applications.
Brand:CaymanSKU:21651 -Out of stock
2-Methylamino-1-phenylbutane is a methamphetamine analog with structural similarity to 2-ethylamino-1-phenylbutane (Item No. 9001863), a stimulant detected in urine samples from persons known to consume the banned sports dietary supplement ‘CRAZE’.{25934} The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:- 2-Methylamino-1-phenylbutane is a methamphetamine analog with structural similarity to 2-ethylamino-1-phenylbutane (Item No. 9001863), a stimulant detected in urine samples from persons known to consume the banned sports dietary supplement ‘CRAZE’.{25934} The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:- 2-Methylamino-1-phenylbutane is a methamphetamine analog with structural similarity to 2-ethylamino-1-phenylbutane (Item No. 9001863), a stimulant detected in urine samples from persons known to consume the banned sports dietary supplement ‘CRAZE’.{25934} The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:- 2-Methylamino-1-phenylbutane is a methamphetamine analog with structural similarity to 2-ethylamino-1-phenylbutane (Item No. 9001863), a stimulant detected in urine samples from persons known to consume the banned sports dietary supplement ‘CRAZE’.{25934} The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:-
2-Methylamphetamine (hydrochloride) (Item No. 24014) is an analytical reference standard catagorized as an amphetamine.{39407} This product is intended for research and forensic applications.
Brand:CaymanSKU:24014 - 1 mgAvailable on backorder
2-Methylamphetamine (hydrochloride) (Item No. 24014) is an analytical reference standard catagorized as an amphetamine.{39407} This product is intended for research and forensic applications.
Brand:CaymanSKU:24014 - 5 mgAvailable on backorder
2-Methylcitric acid is an endogenous tricarboxylic acid formed by the condensation of propionyl-CoA with oxaloacetic acid by citrate synthase under conditions of propionyl-CoA accumulation.{54023} Accumulation of 2-methylcitric acid is associated with cobalamin deficiencies, propionic acidemia, and methylmalonic acidurias.{54023,54024}
Brand:CaymanSKU:29327 - 1 mgAvailable on backorder
2-Methylcitric acid is an endogenous tricarboxylic acid formed by the condensation of propionyl-CoA with oxaloacetic acid by citrate synthase under conditions of propionyl-CoA accumulation.{54023} Accumulation of 2-methylcitric acid is associated with cobalamin deficiencies, propionic acidemia, and methylmalonic acidurias.{54023,54024}
Brand:CaymanSKU:29327 - 10 mgAvailable on backorder
2-Methylcitric acid is an endogenous tricarboxylic acid formed by the condensation of propionyl-CoA with oxaloacetic acid by citrate synthase under conditions of propionyl-CoA accumulation.{54023} Accumulation of 2-methylcitric acid is associated with cobalamin deficiencies, propionic acidemia, and methylmalonic acidurias.{54023,54024}
Brand:CaymanSKU:29327 - 25 mgAvailable on backorder
2-Methylcitric acid is an endogenous tricarboxylic acid formed by the condensation of propionyl-CoA with oxaloacetic acid by citrate synthase under conditions of propionyl-CoA accumulation.{54023} Accumulation of 2-methylcitric acid is associated with cobalamin deficiencies, propionic acidemia, and methylmalonic acidurias.{54023,54024}
Brand:CaymanSKU:29327 - 5 mgAvailable on backorder
4-Methylmethcathinone (4-methyl MC) is a psychoactive synthetic cathinone that has been identified in bath salts and powders.{19498,19193,19508} 2-methyl MC (hydrochloride) is a potential major impurity in preparations of 4-methyl MC. As an isomer of 4-methyl MC, it is likely to have psychoactive properties and may itself be marketed as a designer drug. The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:11223 - 10 mgAvailable on backorder
4-Methylmethcathinone (4-methyl MC) is a psychoactive synthetic cathinone that has been identified in bath salts and powders.{19498,19193,19508} 2-methyl MC (hydrochloride) is a potential major impurity in preparations of 4-methyl MC. As an isomer of 4-methyl MC, it is likely to have psychoactive properties and may itself be marketed as a designer drug. The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:11223 - 5 mgAvailable on backorder
4-Methylmethcathinone (4-methyl MC) is a psychoactive synthetic cathinone that has been identified in bath salts and powders.{19498,19193,19508} 2-methyl MC (hydrochloride) is a potential major impurity in preparations of 4-methyl MC. As an isomer of 4-methyl MC, it is likely to have psychoactive properties and may itself be marketed as a designer drug. The physiological and toxicological properties of this compound have not been determined. This product is intended for forensic and research applications.
Brand:CaymanSKU:11223 - 50 mgAvailable on backorder
2-Methylthioadenosine diphosphate (2-MeSADP) is an agonist of purinergic P2Y receptors with EC50s of 5.13 and 0.89 nM for human recombinant P2Y1 and P2Y12 receptors, respectively.{43571} It also acts as an agonist at rat P2Y1 and P2Y12 and mouse P2Y13 receptors (EC50s = 0.58, 0.89, and 6.2 nM, respectively).{43571,43572} It induces platelet aggregation and inhibits cyclic AMP accumulation in platelet-rich plasma stimulated by prostaglandin E1 (PGE1; Item No. 13010) more potently than ADP (Item Nos. 21121 | 16778).{43573}
Brand:CaymanSKU:21230 -Out of stock
2-Methylthioadenosine diphosphate (2-MeSADP) is an agonist of purinergic P2Y receptors with EC50s of 5.13 and 0.89 nM for human recombinant P2Y1 and P2Y12 receptors, respectively.{43571} It also acts as an agonist at rat P2Y1 and P2Y12 and mouse P2Y13 receptors (EC50s = 0.58, 0.89, and 6.2 nM, respectively).{43571,43572} It induces platelet aggregation and inhibits cyclic AMP accumulation in platelet-rich plasma stimulated by prostaglandin E1 (PGE1; Item No. 13010) more potently than ADP (Item Nos. 21121 | 16778).{43573}
Brand:CaymanSKU:21230 -Out of stock
2-Methylthioadenosine diphosphate (2-MeSADP) is an agonist of purinergic P2Y receptors with EC50s of 5.13 and 0.89 nM for human recombinant P2Y1 and P2Y12 receptors, respectively.{43571} It also acts as an agonist at rat P2Y1 and P2Y12 and mouse P2Y13 receptors (EC50s = 0.58, 0.89, and 6.2 nM, respectively).{43571,43572} It induces platelet aggregation and inhibits cyclic AMP accumulation in platelet-rich plasma stimulated by prostaglandin E1 (PGE1; Item No. 13010) more potently than ADP (Item Nos. 21121 | 16778).{43573}
Brand:CaymanSKU:21230 -Out of stock
2-NBDG is a fluorescent derivative of glucose whose uptake is competitively inhibited by D-glucose (Item No. 23733), but not L-glucose (Item No. 20829) or sucrose, in E. coli.{20027} It has been used to monitor glucose uptake by bacteria and live mammalian cells and in tumor biopsies.{20027,19928,20025,20026} 2-NBDG displays excitation/emission maxima of 475/550 nm, respectively.{20027}
Brand:CaymanSKU:11046 - 1 mgAvailable on backorder
2-NBDG is a fluorescent derivative of glucose whose uptake is competitively inhibited by D-glucose (Item No. 23733), but not L-glucose (Item No. 20829) or sucrose, in E. coli.{20027} It has been used to monitor glucose uptake by bacteria and live mammalian cells and in tumor biopsies.{20027,19928,20025,20026} 2-NBDG displays excitation/emission maxima of 475/550 nm, respectively.{20027}
Brand:CaymanSKU:11046 - 10 mgAvailable on backorder
2-NBDG is a fluorescent derivative of glucose whose uptake is competitively inhibited by D-glucose (Item No. 23733), but not L-glucose (Item No. 20829) or sucrose, in E. coli.{20027} It has been used to monitor glucose uptake by bacteria and live mammalian cells and in tumor biopsies.{20027,19928,20025,20026} 2-NBDG displays excitation/emission maxima of 475/550 nm, respectively.{20027}
Brand:CaymanSKU:11046 - 5 mgAvailable on backorder
2-Nitro-5-thiocyanatobenzoic acid is used to cyanylate proteins and to specifically cleave the amino-terminal peptide bond of cysteine residues.{29392,29391}
Brand:CaymanSKU:-Available on backorder
2-Nitro-5-thiocyanatobenzoic acid is used to cyanylate proteins and to specifically cleave the amino-terminal peptide bond of cysteine residues.{29392,29391}
Brand:CaymanSKU:-Available on backorder
2-NMC (Item No. 22488) is an analytical reference standard. It is a substituted anilide whose physiological and toxicological properties are not known.{39049} This product is intended for research and forensic applications.
Brand:CaymanSKU:22488 -Out of stock
2-NMC (Item No. 22488) is an analytical reference standard. It is a substituted anilide whose physiological and toxicological properties are not known.{39049} This product is intended for research and forensic applications.
Brand:CaymanSKU:22488 -Out of stock
2-nonyl-3-hydroxy-4-Quinolone is a quinolone compound produced by P. aeruginosa and other related bacteria.{31016} It plays a role as a cell-to-cell signaling molecule, acting as a quorum sensing signal molecule to control the expression of many virulence genes as a function of cell population density.{31016} 2-nonyl-3-hydroxy-4-Quinolone is also reported to chelate ferric iron at physiological pH via its 3’-hydroxy group.{31016}
Brand:CaymanSKU:9002699 - 1 mgAvailable on backorder
2-nonyl-3-hydroxy-4-Quinolone is a quinolone compound produced by P. aeruginosa and other related bacteria.{31016} It plays a role as a cell-to-cell signaling molecule, acting as a quorum sensing signal molecule to control the expression of many virulence genes as a function of cell population density.{31016} 2-nonyl-3-hydroxy-4-Quinolone is also reported to chelate ferric iron at physiological pH via its 3’-hydroxy group.{31016}
Brand:CaymanSKU:9002699 - 10 mgAvailable on backorder
2-nonyl-3-hydroxy-4-Quinolone is a quinolone compound produced by P. aeruginosa and other related bacteria.{31016} It plays a role as a cell-to-cell signaling molecule, acting as a quorum sensing signal molecule to control the expression of many virulence genes as a function of cell population density.{31016} 2-nonyl-3-hydroxy-4-Quinolone is also reported to chelate ferric iron at physiological pH via its 3’-hydroxy group.{31016}
Brand:CaymanSKU:9002699 - 5 mgAvailable on backorder
2-Nonylquinolin-4(1H)-one is a quinolone alkaloid that has been found in P. aeruginosa and has diverse biological activities.{58183,58184,58185,58188} It reduces infection of Huh7.5 cells by hepatitis C virus (HCV) with an IC50 value of 1.4 µg/ml.{58183} 2-Nonylquinolin-4(1H)-one (50 and 100 µg/ml) is also active against L. gongylophorus, a symbiotic fungus of the agricultural pest A. sexdens (leaf-cutting ant).{58184} It inhibits activation of nuclear factor of activated T cells (NFAT) induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) and the calcium ionophore A23187 (Item No. 11016) in Jurkat cells (IC50 = 3.44 µM), but not LPS-induced NF-κB activation in RAW 264.7 cells (IC50 = >100 µM), in reporter assays.{58185} This compound is expected to exist in one or both tautomeric forms, depending on experimental conditions.
Brand:CaymanSKU:9003627 - 10 mgAvailable on backorder
2-Nonylquinolin-4(1H)-one is a quinolone alkaloid that has been found in P. aeruginosa and has diverse biological activities.{58183,58184,58185,58188} It reduces infection of Huh7.5 cells by hepatitis C virus (HCV) with an IC50 value of 1.4 µg/ml.{58183} 2-Nonylquinolin-4(1H)-one (50 and 100 µg/ml) is also active against L. gongylophorus, a symbiotic fungus of the agricultural pest A. sexdens (leaf-cutting ant).{58184} It inhibits activation of nuclear factor of activated T cells (NFAT) induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) and the calcium ionophore A23187 (Item No. 11016) in Jurkat cells (IC50 = 3.44 µM), but not LPS-induced NF-κB activation in RAW 264.7 cells (IC50 = >100 µM), in reporter assays.{58185} This compound is expected to exist in one or both tautomeric forms, depending on experimental conditions.
Brand:CaymanSKU:9003627 - 25 mgAvailable on backorder
2-Nonylquinolin-4(1H)-one is a quinolone alkaloid that has been found in P. aeruginosa and has diverse biological activities.{58183,58184,58185,58188} It reduces infection of Huh7.5 cells by hepatitis C virus (HCV) with an IC50 value of 1.4 µg/ml.{58183} 2-Nonylquinolin-4(1H)-one (50 and 100 µg/ml) is also active against L. gongylophorus, a symbiotic fungus of the agricultural pest A. sexdens (leaf-cutting ant).{58184} It inhibits activation of nuclear factor of activated T cells (NFAT) induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) and the calcium ionophore A23187 (Item No. 11016) in Jurkat cells (IC50 = 3.44 µM), but not LPS-induced NF-κB activation in RAW 264.7 cells (IC50 = >100 µM), in reporter assays.{58185} This compound is expected to exist in one or both tautomeric forms, depending on experimental conditions.
Brand:CaymanSKU:9003627 - 5 mgAvailable on backorder
2-Nonylquinolin-4(1H)-one is a quinolone alkaloid that has been found in P. aeruginosa and has diverse biological activities.{58183,58184,58185,58188} It reduces infection of Huh7.5 cells by hepatitis C virus (HCV) with an IC50 value of 1.4 µg/ml.{58183} 2-Nonylquinolin-4(1H)-one (50 and 100 µg/ml) is also active against L. gongylophorus, a symbiotic fungus of the agricultural pest A. sexdens (leaf-cutting ant).{58184} It inhibits activation of nuclear factor of activated T cells (NFAT) induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) and the calcium ionophore A23187 (Item No. 11016) in Jurkat cells (IC50 = 3.44 µM), but not LPS-induced NF-κB activation in RAW 264.7 cells (IC50 = >100 µM), in reporter assays.{58185} This compound is expected to exist in one or both tautomeric forms, depending on experimental conditions.
Brand:CaymanSKU:9003627 - 50 mgAvailable on backorder
2-O-Acetyl-20-hydroxyecdysone is an ecdysone steroid hormone that has been found in plants and animals.{46337} It completely inhibits the growth of the bacteria S. aureus, E. coli, and P. vulgaris, as well as the fungi C. albicans, A. alternata, and F. solani when used at a concentration of 10 µg/ml. 2-O-Acetyl-20-hydroxyecdysone (50 µM) increases aggregation of amyloid-β (1-42) (Aβ42), increases fibril formation by 60%, and decreases oligomer levels in cell-free assays.{46338} It reduces Aβ42-induced cytotoxicity of SH-SY5Y cells when used at concentrations of 5 and 10 µM.
Brand:CaymanSKU:28063 - 1 mgAvailable on backorder
2-O-Acetyl-20-hydroxyecdysone is an ecdysone steroid hormone that has been found in plants and animals.{46337} It completely inhibits the growth of the bacteria S. aureus, E. coli, and P. vulgaris, as well as the fungi C. albicans, A. alternata, and F. solani when used at a concentration of 10 µg/ml. 2-O-Acetyl-20-hydroxyecdysone (50 µM) increases aggregation of amyloid-β (1-42) (Aβ42), increases fibril formation by 60%, and decreases oligomer levels in cell-free assays.{46338} It reduces Aβ42-induced cytotoxicity of SH-SY5Y cells when used at concentrations of 5 and 10 µM.
Brand:CaymanSKU:28063 - 10 mgAvailable on backorder
2-O-Acetyl-20-hydroxyecdysone is an ecdysone steroid hormone that has been found in plants and animals.{46337} It completely inhibits the growth of the bacteria S. aureus, E. coli, and P. vulgaris, as well as the fungi C. albicans, A. alternata, and F. solani when used at a concentration of 10 µg/ml. 2-O-Acetyl-20-hydroxyecdysone (50 µM) increases aggregation of amyloid-β (1-42) (Aβ42), increases fibril formation by 60%, and decreases oligomer levels in cell-free assays.{46338} It reduces Aβ42-induced cytotoxicity of SH-SY5Y cells when used at concentrations of 5 and 10 µM.
Brand:CaymanSKU:28063 - 5 mgAvailable on backorder
2-O-ethyl PAF C-16 is a synthetic PAF analog which contains an ethyl group, attached by an ether linkage, at the sn-2 position. It is a less potent agonist than methylcarbamyl PAF C-16 in the induction of platelet aggregation in both human and rabbit PRP.{613} 2-O-ethyl PAF C-16 causes aggregation of neutrophils in the presence of divalent cations and a desensitization to aggregation in the absence of divalent cations.{614}
Brand:CaymanSKU:60925 - 1 mgAvailable on backorder
2-O-ethyl PAF C-16 is a synthetic PAF analog which contains an ethyl group, attached by an ether linkage, at the sn-2 position. It is a less potent agonist than methylcarbamyl PAF C-16 in the induction of platelet aggregation in both human and rabbit PRP.{613} 2-O-ethyl PAF C-16 causes aggregation of neutrophils in the presence of divalent cations and a desensitization to aggregation in the absence of divalent cations.{614}
Brand:CaymanSKU:60925 - 10 mgAvailable on backorder
2-O-ethyl PAF C-16 is a synthetic PAF analog which contains an ethyl group, attached by an ether linkage, at the sn-2 position. It is a less potent agonist than methylcarbamyl PAF C-16 in the induction of platelet aggregation in both human and rabbit PRP.{613} 2-O-ethyl PAF C-16 causes aggregation of neutrophils in the presence of divalent cations and a desensitization to aggregation in the absence of divalent cations.{614}
Brand:CaymanSKU:60925 - 25 mgAvailable on backorder
2-O-ethyl PAF C-16 is a synthetic PAF analog which contains an ethyl group, attached by an ether linkage, at the sn-2 position. It is a less potent agonist than methylcarbamyl PAF C-16 in the induction of platelet aggregation in both human and rabbit PRP.{613} 2-O-ethyl PAF C-16 causes aggregation of neutrophils in the presence of divalent cations and a desensitization to aggregation in the absence of divalent cations.{614}
Brand:CaymanSKU:60925 - 5 mgAvailable on backorder
2-O-Hexadecyl Glycerol is a β-monoglyceride of palmitic acid (Item No. 10006627). It is an intermediate in the metabolism of triacylglycerols or diacylglycerols and an analog of 2-palmitoyl glycerol (Item No. 17882), an endocannabinoid that fails to bind to cannabinoid CB1 or CB2 receptors, but rather potentiates the biological effects 2-arachidonoyl glycerol (Item No. 62160).{9610}
Brand:CaymanSKU:11924 - 1 mgAvailable on backorder
2-O-Hexadecyl Glycerol is a β-monoglyceride of palmitic acid (Item No. 10006627). It is an intermediate in the metabolism of triacylglycerols or diacylglycerols and an analog of 2-palmitoyl glycerol (Item No. 17882), an endocannabinoid that fails to bind to cannabinoid CB1 or CB2 receptors, but rather potentiates the biological effects 2-arachidonoyl glycerol (Item No. 62160).{9610}
Brand:CaymanSKU:11924 - 10 mgAvailable on backorder
2-O-Hexadecyl Glycerol is a β-monoglyceride of palmitic acid (Item No. 10006627). It is an intermediate in the metabolism of triacylglycerols or diacylglycerols and an analog of 2-palmitoyl glycerol (Item No. 17882), an endocannabinoid that fails to bind to cannabinoid CB1 or CB2 receptors, but rather potentiates the biological effects 2-arachidonoyl glycerol (Item No. 62160).{9610}
Brand:CaymanSKU:11924 - 25 mgAvailable on backorder
2-O-Hexadecyl Glycerol is a β-monoglyceride of palmitic acid (Item No. 10006627). It is an intermediate in the metabolism of triacylglycerols or diacylglycerols and an analog of 2-palmitoyl glycerol (Item No. 17882), an endocannabinoid that fails to bind to cannabinoid CB1 or CB2 receptors, but rather potentiates the biological effects 2-arachidonoyl glycerol (Item No. 62160).{9610}
Brand:CaymanSKU:11924 - 5 mgAvailable on backorder
2-O-methyl PAF C-16 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. Although the biological activities of 2-O-methyl PAF C-16 have not been well characterized, the C-18 analog has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart.{2099} In rat astrocytes, the C-18 analog causes the release of large quantities of NO by a pathway involving activation of NOS.{2985}
Brand:CaymanSKU:60902 - 1 mgAvailable on backorder
2-O-methyl PAF C-16 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. Although the biological activities of 2-O-methyl PAF C-16 have not been well characterized, the C-18 analog has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart.{2099} In rat astrocytes, the C-18 analog causes the release of large quantities of NO by a pathway involving activation of NOS.{2985}
Brand:CaymanSKU:60902 - 10 mgAvailable on backorder
2-O-methyl PAF C-16 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. Although the biological activities of 2-O-methyl PAF C-16 have not been well characterized, the C-18 analog has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart.{2099} In rat astrocytes, the C-18 analog causes the release of large quantities of NO by a pathway involving activation of NOS.{2985}
Brand:CaymanSKU:60902 - 25 mgAvailable on backorder
2-O-methyl PAF C-16 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. Although the biological activities of 2-O-methyl PAF C-16 have not been well characterized, the C-18 analog has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart.{2099} In rat astrocytes, the C-18 analog causes the release of large quantities of NO by a pathway involving activation of NOS.{2985}
Brand:CaymanSKU:60902 - 5 mgAvailable on backorder
2-O-methyl-PAF C-18 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. It has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart.{2099} In rat astrocytes, 2-O-methyl PAF C-18 causes the release of large quantities of nitric oxide by a pathway involving activation of nitric oxide synthase.{2985}
Brand:CaymanSKU:60912 - 10 mgAvailable on backorder
2-O-methyl-PAF C-18 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. It has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart.{2099} In rat astrocytes, 2-O-methyl PAF C-18 causes the release of large quantities of nitric oxide by a pathway involving activation of nitric oxide synthase.{2985}
Brand:CaymanSKU:60912 - 100 mgAvailable on backorder
2-O-methyl-PAF C-18 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. It has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart.{2099} In rat astrocytes, 2-O-methyl PAF C-18 causes the release of large quantities of nitric oxide by a pathway involving activation of nitric oxide synthase.{2985}
Brand:CaymanSKU:60912 - 5 mgAvailable on backorder
2-O-methyl-PAF C-18 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. It has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart.{2099} In rat astrocytes, 2-O-methyl PAF C-18 causes the release of large quantities of nitric oxide by a pathway involving activation of nitric oxide synthase.{2985}
Brand:CaymanSKU:60912 - 50 mgAvailable on backorder
2-O-α-D-Glucopyranosyl-L-ascorbic acid (AA-2G) is a glucosylated derivative of L-ascorbic acid (Item No. 14656) that has antioxidant and radioprotective activities.{54442,54443,54444} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (EC50 = 61 μM in 60% ethanol).{54442} AA-2G (5 mM) inhibits γ-radiation-induced cell death in CHO-10B2 and radiosensitive xrs5 cells, as well as UVC- or broadband UVB-induced cell death in CHO-10B2 and UV-sensitive UV135 cells.{54443} It is hydrolyzed to ascorbic acid by α-glucosidase and increases serum levels of ascorbic acid in rats and guinea pigs when administered orally at doses of 19.2 and 96 mg/animal, respectively.{54444} AA-2G (19.2 mg/animal per day) reverses weight loss and inhibits subcutaneous hemorrhage in guinea pigs fed a vitamin C-deficient diet.
Brand:CaymanSKU:31402 - 10 gAvailable on backorder
2-O-α-D-Glucopyranosyl-L-ascorbic acid (AA-2G) is a glucosylated derivative of L-ascorbic acid (Item No. 14656) that has antioxidant and radioprotective activities.{54442,54443,54444} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (EC50 = 61 μM in 60% ethanol).{54442} AA-2G (5 mM) inhibits γ-radiation-induced cell death in CHO-10B2 and radiosensitive xrs5 cells, as well as UVC- or broadband UVB-induced cell death in CHO-10B2 and UV-sensitive UV135 cells.{54443} It is hydrolyzed to ascorbic acid by α-glucosidase and increases serum levels of ascorbic acid in rats and guinea pigs when administered orally at doses of 19.2 and 96 mg/animal, respectively.{54444} AA-2G (19.2 mg/animal per day) reverses weight loss and inhibits subcutaneous hemorrhage in guinea pigs fed a vitamin C-deficient diet.
Brand:CaymanSKU:31402 - 25 gAvailable on backorder
2-O-α-D-Glucopyranosyl-L-ascorbic acid (AA-2G) is a glucosylated derivative of L-ascorbic acid (Item No. 14656) that has antioxidant and radioprotective activities.{54442,54443,54444} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (EC50 = 61 μM in 60% ethanol).{54442} AA-2G (5 mM) inhibits γ-radiation-induced cell death in CHO-10B2 and radiosensitive xrs5 cells, as well as UVC- or broadband UVB-induced cell death in CHO-10B2 and UV-sensitive UV135 cells.{54443} It is hydrolyzed to ascorbic acid by α-glucosidase and increases serum levels of ascorbic acid in rats and guinea pigs when administered orally at doses of 19.2 and 96 mg/animal, respectively.{54444} AA-2G (19.2 mg/animal per day) reverses weight loss and inhibits subcutaneous hemorrhage in guinea pigs fed a vitamin C-deficient diet.
Brand:CaymanSKU:31402 - 5 gAvailable on backorder
2-O-α-D-Glucopyranosyl-L-ascorbic acid (AA-2G) is a glucosylated derivative of L-ascorbic acid (Item No. 14656) that has antioxidant and radioprotective activities.{54442,54443,54444} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (EC50 = 61 μM in 60% ethanol).{54442} AA-2G (5 mM) inhibits γ-radiation-induced cell death in CHO-10B2 and radiosensitive xrs5 cells, as well as UVC- or broadband UVB-induced cell death in CHO-10B2 and UV-sensitive UV135 cells.{54443} It is hydrolyzed to ascorbic acid by α-glucosidase and increases serum levels of ascorbic acid in rats and guinea pigs when administered orally at doses of 19.2 and 96 mg/animal, respectively.{54444} AA-2G (19.2 mg/animal per day) reverses weight loss and inhibits subcutaneous hemorrhage in guinea pigs fed a vitamin C-deficient diet.
Brand:CaymanSKU:31402 - 50 gAvailable on backorder
2-Oleoyl glycerol (2-OG) is a natural monoacylglycerol with an 18:1 oleoyl group at the sn-2 position of glycerol. 2-OG, like 2-arachidonoyl glycerol (2-AG; Item No. 62160), is metabolized by monoacylglycerol lipase, but, unlike 2-AG, it is not metabolized by cyclooxygenases or lipoxygenases.{15412,14196,27758} 2-OG is an agonist of GPR119 (EC50 = 2.5 µM), stimulating the release of glucagon-like peptide-1 from intestinal L-cells.{27759}
Brand:CaymanSKU:-Out of stock
2-Oleoyl glycerol (2-OG) is a natural monoacylglycerol with an 18:1 oleoyl group at the sn-2 position of glycerol. 2-OG, like 2-arachidonoyl glycerol (2-AG; Item No. 62160), is metabolized by monoacylglycerol lipase, but, unlike 2-AG, it is not metabolized by cyclooxygenases or lipoxygenases.{15412,14196,27758} 2-OG is an agonist of GPR119 (EC50 = 2.5 µM), stimulating the release of glucagon-like peptide-1 from intestinal L-cells.{27759}
Brand:CaymanSKU:-Out of stock
2-Oleoyl glycerol (2-OG) is a natural monoacylglycerol with an 18:1 oleoyl group at the sn-2 position of glycerol. 2-OG, like 2-arachidonoyl glycerol (2-AG; Item No. 62160), is metabolized by monoacylglycerol lipase, but, unlike 2-AG, it is not metabolized by cyclooxygenases or lipoxygenases.{15412,14196,27758} 2-OG is an agonist of GPR119 (EC50 = 2.5 µM), stimulating the release of glucagon-like peptide-1 from intestinal L-cells.{27759}
Brand:CaymanSKU:-Out of stock
2-Oleoyl glycerol (2-OG) is a natural monoacylglycerol with an 18:1 oleoyl group at the sn-2 position of glycerol. 2-OG, like 2-arachidonoyl glycerol (2-AG; Item No. 62160), is metabolized by monoacylglycerol lipase, but, unlike 2-AG, it is not metabolized by cyclooxygenases or lipoxygenases.{15412,14196,27758} 2-OG is an agonist of GPR119 (EC50 = 2.5 µM), stimulating the release of glucagon-like peptide-1 from intestinal L-cells.{27759}
Brand:CaymanSKU:-Out of stock
2-oxo Clopidogrel is an intermediary metabolite of clopidogrel (Item No. 13657). Clopidogrel is a prodrug that is converted to its active metabolite via two sequential oxidative steps.{32041} The first step leads to formation of 2-oxo clopidogrel, followed by conversion to the active metabolite, which binds specifically and irreversibly to the platelet P2Y12 purinergic receptor, inhibiting ADP-mediated platelet activation and aggregation.{32041}
Brand:CaymanSKU:20394 -Available on backorder
2-oxo Clopidogrel is an intermediary metabolite of clopidogrel (Item No. 13657). Clopidogrel is a prodrug that is converted to its active metabolite via two sequential oxidative steps.{32041} The first step leads to formation of 2-oxo clopidogrel, followed by conversion to the active metabolite, which binds specifically and irreversibly to the platelet P2Y12 purinergic receptor, inhibiting ADP-mediated platelet activation and aggregation.{32041}
Brand:CaymanSKU:20394 -Available on backorder
2-oxo Clopidogrel is an intermediary metabolite of clopidogrel (Item No. 13657). Clopidogrel is a prodrug that is converted to its active metabolite via two sequential oxidative steps.{32041} The first step leads to formation of 2-oxo clopidogrel, followed by conversion to the active metabolite, which binds specifically and irreversibly to the platelet P2Y12 purinergic receptor, inhibiting ADP-mediated platelet activation and aggregation.{32041}
Brand:CaymanSKU:20394 -Available on backorder
2-Arachidonoyl glycerol (2-AG; Item No. 62160) is an endogenous agonist of the CB1 and CB2 cannabinoid receptors. 2-Palmitoyl glycerol is a fatty acid ester that does not bind directly to cannabinoid receptors, nor inhibit adenylyl cyclase, but rather potentiates the activity of 2-AG (and other endocannabinoids) to bind to CB1 and CB2 and inhibit adenylyl cyclase.{9610} This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release.{9610} 2-Palmitoyl glycerol and related endogenous fatty acid derivatives have been shown to interact with endocannabinoids in the modulation of pain sensitivity.{29117}
Brand:CaymanSKU:-Available on backorder
2-Arachidonoyl glycerol (2-AG; Item No. 62160) is an endogenous agonist of the CB1 and CB2 cannabinoid receptors. 2-Palmitoyl glycerol is a fatty acid ester that does not bind directly to cannabinoid receptors, nor inhibit adenylyl cyclase, but rather potentiates the activity of 2-AG (and other endocannabinoids) to bind to CB1 and CB2 and inhibit adenylyl cyclase.{9610} This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release.{9610} 2-Palmitoyl glycerol and related endogenous fatty acid derivatives have been shown to interact with endocannabinoids in the modulation of pain sensitivity.{29117}
Brand:CaymanSKU:-Available on backorder
2-Arachidonoyl glycerol (2-AG; Item No. 62160) is an endogenous agonist of the CB1 and CB2 cannabinoid receptors. 2-Palmitoyl glycerol is a fatty acid ester that does not bind directly to cannabinoid receptors, nor inhibit adenylyl cyclase, but rather potentiates the activity of 2-AG (and other endocannabinoids) to bind to CB1 and CB2 and inhibit adenylyl cyclase.{9610} This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release.{9610} 2-Palmitoyl glycerol and related endogenous fatty acid derivatives have been shown to interact with endocannabinoids in the modulation of pain sensitivity.{29117}
Brand:CaymanSKU:-Available on backorder
2-Arachidonoyl glycerol (2-AG; Item No. 62160) is an endogenous agonist of the CB1 and CB2 cannabinoid receptors. 2-Palmitoyl glycerol is a fatty acid ester that does not bind directly to cannabinoid receptors, nor inhibit adenylyl cyclase, but rather potentiates the activity of 2-AG (and other endocannabinoids) to bind to CB1 and CB2 and inhibit adenylyl cyclase.{9610} This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release.{9610} 2-Palmitoyl glycerol and related endogenous fatty acid derivatives have been shown to interact with endocannabinoids in the modulation of pain sensitivity.{29117}
Brand:CaymanSKU:-Available on backorder
2-Phenethylamine is a natural monoamine alkaloid that acts as neuromodulator in the central nervous system. It stimulates the release of norepinephrine and dopamine and is metabolized by monoamine oxidases as well as other enzymes.{21276,26163,26162} This product is intended for forensic and research applications.
Brand:CaymanSKU:- 2-Phenethylamine is a natural monoamine alkaloid that acts as neuromodulator in the central nervous system. It stimulates the release of norepinephrine and dopamine and is metabolized by monoamine oxidases as well as other enzymes.{21276,26163,26162} This product is intended for forensic and research applications.
Brand:CaymanSKU:- 2-Phenethylamine is a natural monoamine alkaloid that acts as neuromodulator in the central nervous system. It stimulates the release of norepinephrine and dopamine and is metabolized by monoamine oxidases as well as other enzymes.{21276,26163,26162} This product is intended for forensic and research applications.
Brand:CaymanSKU:-
2-Phenyl-2-(1-piperidinyl)propane is an analog of phencyclidine that acts as a mechanism-based inactivator of human cytochrome P450 (CYP) 2B6 (Ki = 5.6 µM; IC50 = 5.1 µM).{29044} It is 15-fold more selective for inhibition of CYP2B6 over CYP2D6 and 40-60-fold more selective for CYP2B6 over CYP1A2, CYP2A6, CYP2Cs, and CYP3A.{29044}
Brand:CaymanSKU:-Available on backorder
2-Phenyl-2-(1-piperidinyl)propane is an analog of phencyclidine that acts as a mechanism-based inactivator of human cytochrome P450 (CYP) 2B6 (Ki = 5.6 µM; IC50 = 5.1 µM).{29044} It is 15-fold more selective for inhibition of CYP2B6 over CYP2D6 and 40-60-fold more selective for CYP2B6 over CYP1A2, CYP2A6, CYP2Cs, and CYP3A.{29044}
Brand:CaymanSKU:-Available on backorder
2-Phenyl-2-(1-piperidinyl)propane is an analog of phencyclidine that acts as a mechanism-based inactivator of human cytochrome P450 (CYP) 2B6 (Ki = 5.6 µM; IC50 = 5.1 µM).{29044} It is 15-fold more selective for inhibition of CYP2B6 over CYP2D6 and 40-60-fold more selective for CYP2B6 over CYP1A2, CYP2A6, CYP2Cs, and CYP3A.{29044}
Brand:CaymanSKU:-Available on backorder
2-Phenyl-2-(1-piperidinyl)propane is an analog of phencyclidine that acts as a mechanism-based inactivator of human cytochrome P450 (CYP) 2B6 (Ki = 5.6 µM; IC50 = 5.1 µM).{29044} It is 15-fold more selective for inhibition of CYP2B6 over CYP2D6 and 40-60-fold more selective for CYP2B6 over CYP1A2, CYP2A6, CYP2Cs, and CYP3A.{29044}
Brand:CaymanSKU:-Available on backorder
Brand:CaymanSKU:11057 - 1 gAvailable on backorder
Brand:CaymanSKU:11057 - 5 gAvailable on backorder
Brand:CaymanSKU:11057 - 500 mgAvailable on backorder
2-Phenylaminoadenosine is an adenosine receptor agonist.{48560} It binds to adenosine A1 receptors in rat cortical membranes (IC50 = 910 nM) and A2 receptors in rat striatal membranes (IC50 = 115 nM). 2-Phenylaminoadenosine increases coronary flow in a perfused working rat heart model ex vivo (EC25 = 110 nM). It decreases blood pressure in normotensive (ED25 = 28 μg/kg) and spontaneously hypertensive rats (SHR; ED30 = 5.32 μg/kg).{48560,48561} 2-Phenylaminoadenosine (500 nmol/kg) increases L-dihydroxyphenylalanine (L-DOPA; Item No. 13248) accumulation in rat striatum.{48562} It also inhibits conditioned avoidance responding (CAR) to electric shock in rats (ED50 = 1.3 mg/kg).{48563}
Brand:CaymanSKU:28734 - 10 mgAvailable on backorder