Cayman
Showing 3751–3900 of 45550 results
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15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 µM.{951}
Brand:CaymanSKU:37720 - 100 µgAvailable on backorder
15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 µM.{951}
Brand:CaymanSKU:37720 - 25 µgAvailable on backorder
15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 µM.{951}
Brand:CaymanSKU:37720 - 250 µgAvailable on backorder
15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 µM.{951}
Brand:CaymanSKU:37720 - 50 µgAvailable on backorder
15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid (Item Nos. 90110 | 90110.1 | 21908) by 15-lipoxygenase (15-LO).{6407,54203} Serum levels of 15(S)-HEPE are elevated in patients with asthma.{54204}
Brand:CaymanSKU:32710 - 100 µgAvailable on backorder
15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid (Item Nos. 90110 | 90110.1 | 21908) by 15-lipoxygenase (15-LO).{6407,54203} Serum levels of 15(S)-HEPE are elevated in patients with asthma.{54204}
Brand:CaymanSKU:32710 - 25 µgAvailable on backorder
15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid (Item Nos. 90110 | 90110.1 | 21908) by 15-lipoxygenase (15-LO).{6407,54203} Serum levels of 15(S)-HEPE are elevated in patients with asthma.{54204}
Brand:CaymanSKU:32710 - 250 µgAvailable on backorder
15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid (Item Nos. 90110 | 90110.1 | 21908) by 15-lipoxygenase (15-LO).{6407,54203} Serum levels of 15(S)-HEPE are elevated in patients with asthma.{54204}
Brand:CaymanSKU:32710 - 50 µgAvailable on backorder
15(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 15-LO. The biosynthesis of 15-HEPE from EPA in guinea pig epidermal enzyme preparations has been documented.{6407} 15(S)-HEPE generated by soybean lipoxygenation of EPA inhibits RBL-1 cell 5-LO with an IC50 value of 28 µM.{6407} 15(S)-HEPE MaxSpec® standard is a quantitative grade standard of 15(S)-HEPE (Item No. 32710) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 15(S)-HEPE MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Brand:CaymanSKU:26003 - 10 µgAvailable on backorder
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes.{118} 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.{373}
Brand:CaymanSKU:34720 - 100 µgAvailable on backorder
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes.{118} 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.{373}
Brand:CaymanSKU:34720 - 25 µgAvailable on backorder
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes.{118} 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.{373}
Brand:CaymanSKU:34720 - 50 µgAvailable on backorder
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes.{118} 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.{373}
Brand:CaymanSKU:34720 - 500 µgAvailable on backorder
Brand:CaymanSKU:434722 - 100 dtnAvailable on backorder
Brand:CaymanSKU:434722 - 500 dtnAvailable on backorder
15(S)-HETE is produced from arachidonic acid by the enzyme 15-lipoxygenase (15-LO). In humans it is formed primarily in the respiratory epithelium, leukocytes, and reticulocytes.{2363} 15(S)-HETE has been detected in high concentrations in nasal secretions and may contribute to allergic rhinitis.{373} 15(S)-HETE has anti-inflammatory properties, inhibiting carrageenan-induced arthritis and lowering leukotriene B4 (LTB4) concentrations in the synovial fluid of dogs.{1014} It may regulate T-lymphocytes by inhibiting 5- and 12-LOs.{682} It is also a vasoconstrictor, constricting cerebral and coronary arteries of dogs in vitro and cerebral arteries of pigs in vivo.{1015} 15(S)-HETE may also play a role in cancer, inhibiting apoptosis by carcinosarcoma cells.{3814} Our 15(S)-HETE ELISA is a competitive assay that permits the measurement of 15(S)-HETE within the range of 78-10,000 pg/ml, typically with a sensitivity (80% B/B0) of 185.4 pg/ml. This assay is very specific for 15(S)-HETE, showing very low crossreactivity to other HETEs.
Brand:CaymanSKU:534721 - 480 solid wellsAvailable on backorder
15(S)-HETE is produced from arachidonic acid by the enzyme 15-lipoxygenase (15-LO). In humans it is formed primarily in the respiratory epithelium, leukocytes, and reticulocytes.{2363} 15(S)-HETE has been detected in high concentrations in nasal secretions and may contribute to allergic rhinitis.{373} 15(S)-HETE has anti-inflammatory properties, inhibiting carrageenan-induced arthritis and lowering leukotriene B4 (LTB4) concentrations in the synovial fluid of dogs.{1014} It may regulate T-lymphocytes by inhibiting 5- and 12-LOs.{682} It is also a vasoconstrictor, constricting cerebral and coronary arteries of dogs in vitro and cerebral arteries of pigs in vivo.{1015} 15(S)-HETE may also play a role in cancer, inhibiting apoptosis by carcinosarcoma cells.{3814} Our 15(S)-HETE ELISA is a competitive assay that permits the measurement of 15(S)-HETE within the range of 78-10,000 pg/ml, typically with a sensitivity (80% B/B0) of 185.4 pg/ml. This assay is very specific for 15(S)-HETE, showing very low crossreactivity to other HETEs.
Brand:CaymanSKU:534721 - 480 strip wellsAvailable on backorder
15(S)-HETE is produced from arachidonic acid by the enzyme 15-lipoxygenase (15-LO). In humans it is formed primarily in the respiratory epithelium, leukocytes, and reticulocytes.{2363} 15(S)-HETE has been detected in high concentrations in nasal secretions and may contribute to allergic rhinitis.{373} 15(S)-HETE has anti-inflammatory properties, inhibiting carrageenan-induced arthritis and lowering leukotriene B4 (LTB4) concentrations in the synovial fluid of dogs.{1014} It may regulate T-lymphocytes by inhibiting 5- and 12-LOs.{682} It is also a vasoconstrictor, constricting cerebral and coronary arteries of dogs in vitro and cerebral arteries of pigs in vivo.{1015} 15(S)-HETE may also play a role in cancer, inhibiting apoptosis by carcinosarcoma cells.{3814} Our 15(S)-HETE ELISA is a competitive assay that permits the measurement of 15(S)-HETE within the range of 78-10,000 pg/ml, typically with a sensitivity (80% B/B0) of 185.4 pg/ml. This assay is very specific for 15(S)-HETE, showing very low crossreactivity to other HETEs.
Brand:CaymanSKU:534721 - 96 solid wellsAvailable on backorder
15(S)-HETE is produced from arachidonic acid by the enzyme 15-lipoxygenase (15-LO). In humans it is formed primarily in the respiratory epithelium, leukocytes, and reticulocytes.{2363} 15(S)-HETE has been detected in high concentrations in nasal secretions and may contribute to allergic rhinitis.{373} 15(S)-HETE has anti-inflammatory properties, inhibiting carrageenan-induced arthritis and lowering leukotriene B4 (LTB4) concentrations in the synovial fluid of dogs.{1014} It may regulate T-lymphocytes by inhibiting 5- and 12-LOs.{682} It is also a vasoconstrictor, constricting cerebral and coronary arteries of dogs in vitro and cerebral arteries of pigs in vivo.{1015} 15(S)-HETE may also play a role in cancer, inhibiting apoptosis by carcinosarcoma cells.{3814} Our 15(S)-HETE ELISA is a competitive assay that permits the measurement of 15(S)-HETE within the range of 78-10,000 pg/ml, typically with a sensitivity (80% B/B0) of 185.4 pg/ml. This assay is very specific for 15(S)-HETE, showing very low crossreactivity to other HETEs.
Brand:CaymanSKU:534721 - 96 strip wellsAvailable on backorder
Brand:CaymanSKU:434724 - 1 eaAvailable on backorder
Arachidonoyl ethanolamide (AEA; Item No. 90050) was the first endogenous cannabinoid (CB) to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as THC.{1134,2713} Since that time, a number of related endocannabinoids have been isolated, most notably 2-arachidonoyl glycerol (Item No. 62160).{2713} Lipoxygenases, especially rabbit reticulocyte and soybean 15-lipoxygenases, actively convert endocannabinoids to their 15(S)-hydroperoxy and hydroxy metabolites.{11412} 15(S)-HETE ethanolamide is less potent than AEA at the CB1 receptor (Ki of 600 versus 90 nM). 15(S)-HETE ethanolamide also inhibits fatty acid amide hydrolase.{11365}
Brand:CaymanSKU:10169 - 100 µgAvailable on backorder
Arachidonoyl ethanolamide (AEA; Item No. 90050) was the first endogenous cannabinoid (CB) to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as THC.{1134,2713} Since that time, a number of related endocannabinoids have been isolated, most notably 2-arachidonoyl glycerol (Item No. 62160).{2713} Lipoxygenases, especially rabbit reticulocyte and soybean 15-lipoxygenases, actively convert endocannabinoids to their 15(S)-hydroperoxy and hydroxy metabolites.{11412} 15(S)-HETE ethanolamide is less potent than AEA at the CB1 receptor (Ki of 600 versus 90 nM). 15(S)-HETE ethanolamide also inhibits fatty acid amide hydrolase.{11365}
Brand:CaymanSKU:10169 - 25 µgAvailable on backorder
Arachidonoyl ethanolamide (AEA; Item No. 90050) was the first endogenous cannabinoid (CB) to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as THC.{1134,2713} Since that time, a number of related endocannabinoids have been isolated, most notably 2-arachidonoyl glycerol (Item No. 62160).{2713} Lipoxygenases, especially rabbit reticulocyte and soybean 15-lipoxygenases, actively convert endocannabinoids to their 15(S)-hydroperoxy and hydroxy metabolites.{11412} 15(S)-HETE ethanolamide is less potent than AEA at the CB1 receptor (Ki of 600 versus 90 nM). 15(S)-HETE ethanolamide also inhibits fatty acid amide hydrolase.{11365}
Brand:CaymanSKU:10169 - 50 µgAvailable on backorder
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes.{118} 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.{373} 15(S)-HETE MaxSpec® standard is a quantitative grade standard of 15(S)-HETE (Item No. 34720) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 15(S)-HETE MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Brand:CaymanSKU:10007251 - 100 µgAvailable on backorder
15(S)-HETE methyl ester is a synthetic derivative of 15(S)-HETE (Item No. 34720), a major arachidonic acid metabolite from the 15-lipoxygenase pathway. Methyl esters of lipids are commonly used in formulations of nutritional supplements.
Brand:CaymanSKU:21327 -Out of stock
15(S)-HETE methyl ester is a synthetic derivative of 15(S)-HETE (Item No. 34720), a major arachidonic acid metabolite from the 15-lipoxygenase pathway. Methyl esters of lipids are commonly used in formulations of nutritional supplements.
Brand:CaymanSKU:21327 -Out of stock
15(S)-HETE methyl ester is a synthetic derivative of 15(S)-HETE (Item No. 34720), a major arachidonic acid metabolite from the 15-lipoxygenase pathway. Methyl esters of lipids are commonly used in formulations of nutritional supplements.
Brand:CaymanSKU:21327 -Out of stock
15(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 15(S)-HETE by GC- or LC-MS. 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes.{118} 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.{373}
Brand:CaymanSKU:334720 - 100 µgAvailable on backorder
15(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 15(S)-HETE by GC- or LC-MS. 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes.{118} 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.{373}
Brand:CaymanSKU:334720 - 25 µgAvailable on backorder
15(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 15(S)-HETE by GC- or LC-MS. 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes.{118} 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.{373}
Brand:CaymanSKU:334720 - 50 µgAvailable on backorder
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid (DGLA; Item No. 90230). It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 µM.{2692} In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.{951}
Brand:CaymanSKU:36720 - 100 µgAvailable on backorder
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid (DGLA; Item No. 90230). It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 µM.{2692} In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.{951}
Brand:CaymanSKU:36720 - 25 µgAvailable on backorder
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid (DGLA; Item No. 90230). It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 µM.{2692} In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.{951}
Brand:CaymanSKU:36720 - 50 µgAvailable on backorder
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid (DGLA; Item No. 90230). It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 µM.{2692} In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.{951}
Brand:CaymanSKU:36720 - 500 µgAvailable on backorder
15(S)-HpEDE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosadienoic acid. Although the biological activities of 15(S)-HpEDE have not been well characterized, it is expected to behave similarly to 15(S)-HpETE (Cat. No. 44720).
Brand:CaymanSKU:47720 - 100 µgAvailable on backorder
15(S)-HpEDE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosadienoic acid. Although the biological activities of 15(S)-HpEDE have not been well characterized, it is expected to behave similarly to 15(S)-HpETE (Cat. No. 44720).
Brand:CaymanSKU:47720 - 25 µgAvailable on backorder
15(S)-HpEDE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosadienoic acid. Although the biological activities of 15(S)-HpEDE have not been well characterized, it is expected to behave similarly to 15(S)-HpETE (Cat. No. 44720).
Brand:CaymanSKU:47720 - 250 µgAvailable on backorder
15(S)-HpEDE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosadienoic acid. Although the biological activities of 15(S)-HpEDE have not been well characterized, it is expected to behave similarly to 15(S)-HpETE (Cat. No. 44720).
Brand:CaymanSKU:47720 - 50 µgAvailable on backorder
15(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosapentaenoic acid. Although the biological activities of 15(S)-HpEPE have not been well characterized, it is expected to behave similarly to 15(S)-HpETE (Catalog No. 44720).
Brand:CaymanSKU:42710 - 100 µgAvailable on backorder
15(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosapentaenoic acid. Although the biological activities of 15(S)-HpEPE have not been well characterized, it is expected to behave similarly to 15(S)-HpETE (Catalog No. 44720).
Brand:CaymanSKU:42710 - 25 µgAvailable on backorder
15(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosapentaenoic acid. Although the biological activities of 15(S)-HpEPE have not been well characterized, it is expected to behave similarly to 15(S)-HpETE (Catalog No. 44720).
Brand:CaymanSKU:42710 - 250 µgAvailable on backorder
15(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosapentaenoic acid. Although the biological activities of 15(S)-HpEPE have not been well characterized, it is expected to behave similarly to 15(S)-HpETE (Catalog No. 44720).
Brand:CaymanSKU:42710 - 50 µgAvailable on backorder
15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4{391} or reduced to 15(S)-HETE by peroxidases.{3959,391} 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1.{4194} 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO.{3959,454,588}
Brand:CaymanSKU:44720 - 100 µgAvailable on backorder
15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4{391} or reduced to 15(S)-HETE by peroxidases.{3959,391} 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1.{4194} 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO.{3959,454,588}
Brand:CaymanSKU:44720 - 25 µgAvailable on backorder
15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4{391} or reduced to 15(S)-HETE by peroxidases.{3959,391} 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1.{4194} 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO.{3959,454,588}
Brand:CaymanSKU:44720 - 250 µgAvailable on backorder
15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4{391} or reduced to 15(S)-HETE by peroxidases.{3959,391} 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1.{4194} 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO.{3959,454,588}
Brand:CaymanSKU:44720 - 50 µgAvailable on backorder
15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.{9736} A 3 µg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys.{9736} 15(S)-Latanoprost is a potential impurity in most commercial preparations of the latanoprost bulk drug product.
Brand:CaymanSKU:-Out of stock
15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.{9736} A 3 µg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys.{9736} 15(S)-Latanoprost is a potential impurity in most commercial preparations of the latanoprost bulk drug product.
Brand:CaymanSKU:-Out of stock
15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.{9736} A 3 µg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys.{9736} 15(S)-Latanoprost is a potential impurity in most commercial preparations of the latanoprost bulk drug product.
Brand:CaymanSKU:-Out of stock
15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.{9736} A 3 µg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys.{9736} 15(S)-Latanoprost is a potential impurity in most commercial preparations of the latanoprost bulk drug product.
Brand:CaymanSKU:-Out of stock
16-doxyl Stearic acid is a form of stearic acid (Item No. 10011298) that contains a 4,4-dimethyl-3-oxazolinyloxy (DOXYL) group, creating a hydrophobic spin label. It is commonly used to study molecular aspects of membranes and hydrophobic proteins.{48524,48525,48526}
Brand:CaymanSKU:20355 -Available on backorder
16-doxyl Stearic acid is a form of stearic acid (Item No. 10011298) that contains a 4,4-dimethyl-3-oxazolinyloxy (DOXYL) group, creating a hydrophobic spin label. It is commonly used to study molecular aspects of membranes and hydrophobic proteins.{48524,48525,48526}
Brand:CaymanSKU:20355 -Available on backorder
16-doxyl Stearic acid is a form of stearic acid (Item No. 10011298) that contains a 4,4-dimethyl-3-oxazolinyloxy (DOXYL) group, creating a hydrophobic spin label. It is commonly used to study molecular aspects of membranes and hydrophobic proteins.{48524,48525,48526}
Brand:CaymanSKU:20355 -Available on backorder
16-doxyl Stearic acid is a form of stearic acid (Item No. 10011298) that contains a 4,4-dimethyl-3-oxazolinyloxy (DOXYL) group, creating a hydrophobic spin label. It is commonly used to study molecular aspects of membranes and hydrophobic proteins.{48524,48525,48526}
Brand:CaymanSKU:20355 -Available on backorder
16-epi Latrunculin B, first isolated from the Red Sea sponge N. magnifica, is a stereoisomer of the actin polymerization inhibitor, latrunculin B (Item No. 10010631).{31273,31274} At 5-10 µg/ml, 16-epi latrunculin B can disrupt microfilament activity in an actin disruption assay.{31274} It also demonstrates cytotoxic activity in mouse KA31T and NIH3T3 tumor cells (GI50s = 1 and 4 µg/ml, respectively) and antiviral activity against herpes simplex type 1 virus (ED50 = 1 µg/ml).{31273}
Brand:CaymanSKU:19608 -Available on backorder
16-hydroxy Hexadecanoic acid is a metabolite of the saturated fatty acid palmitic acid (16:0) that has been hydroxylated on its terminal (ω) carbon. It is produced by ω-hydroxylation of palmitic acid by cytochrome P450 in both plants and animals.{19460,19462,19461,19458} In plants, it is commonly a component of cutin.{19459,19462}
Brand:CaymanSKU:9000789 - 1 gAvailable on backorder
16-hydroxy Hexadecanoic acid is a metabolite of the saturated fatty acid palmitic acid (16:0) that has been hydroxylated on its terminal (ω) carbon. It is produced by ω-hydroxylation of palmitic acid by cytochrome P450 in both plants and animals.{19460,19462,19461,19458} In plants, it is commonly a component of cutin.{19459,19462}
Brand:CaymanSKU:9000789 - 5 gAvailable on backorder
16-O-Methylcafestol is a diterpene that has been found in robusta (C. canephora) coffee beans.{42528} It has been used as a marker for robusta contamination and or adulteration of Arabica (C. arabica) roast coffee grounds in commercial production.
Brand:CaymanSKU:20259 -Available on backorder
16-O-Methylcafestol is a diterpene that has been found in robusta (C. canephora) coffee beans.{42528} It has been used as a marker for robusta contamination and or adulteration of Arabica (C. arabica) roast coffee grounds in commercial production.
Brand:CaymanSKU:20259 -Available on backorder
16-O-Methylcafestol is a diterpene that has been found in robusta (C. canephora) coffee beans.{42528} It has been used as a marker for robusta contamination and or adulteration of Arabica (C. arabica) roast coffee grounds in commercial production.
Brand:CaymanSKU:20259 -Available on backorder
16-Oxokahweol is a synthetic diterpene and derivative of kahweol (Item No. 14015).{53495} It increases cytosolic glutathione S-transferase (GST) activity and acid-soluble sulfhydryl levels in mouse liver and small bowel mucosa when administered at a dose of 10 µmol/animal once per day for three days.
Brand:CaymanSKU:30117 - 1 mgAvailable on backorder
16-Oxokahweol is a synthetic diterpene and derivative of kahweol (Item No. 14015).{53495} It increases cytosolic glutathione S-transferase (GST) activity and acid-soluble sulfhydryl levels in mouse liver and small bowel mucosa when administered at a dose of 10 µmol/animal once per day for three days.
Brand:CaymanSKU:30117 - 10 mgAvailable on backorder
16-Oxokahweol is a synthetic diterpene and derivative of kahweol (Item No. 14015).{53495} It increases cytosolic glutathione S-transferase (GST) activity and acid-soluble sulfhydryl levels in mouse liver and small bowel mucosa when administered at a dose of 10 µmol/animal once per day for three days.
Brand:CaymanSKU:30117 - 5 mgAvailable on backorder
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.{187,421,1651} 16-phenoxy PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.{2058} Ethyl amides of PGs serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.
Brand:CaymanSKU:10009875 - 1 mgAvailable on backorder
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.{187,421,1651} 16-phenoxy PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.{2058} Ethyl amides of PGs serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.
Brand:CaymanSKU:10009875 - 10 mgAvailable on backorder
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.{187,421,1651} 16-phenoxy PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.{2058} Ethyl amides of PGs serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.
Brand:CaymanSKU:10009875 - 5 mgAvailable on backorder
16-phenoxy tetranor PGA2 is a minor metabolite found in human plasma after intravenous administration of sulprostone.{3387} Its biological activity has not been studied or reported in the literature.
Brand:CaymanSKU:10285 - 1 mgAvailable on backorder
16-phenoxy tetranor PGA2 is a minor metabolite found in human plasma after intravenous administration of sulprostone.{3387} Its biological activity has not been studied or reported in the literature.
Brand:CaymanSKU:10285 - 10 mgAvailable on backorder
16-phenoxy tetranor PGA2 is a minor metabolite found in human plasma after intravenous administration of sulprostone.{3387} Its biological activity has not been studied or reported in the literature.
Brand:CaymanSKU:10285 - 5 mgAvailable on backorder
16-phenoxy tetranor PGE2 is the free acid form of sulprostone formed by the hydrolysis of the methylsulfonamide bond.{3387} 16-phenoxy tetranor PGE2 is a minor metabolite of sulprostone found in human plasma after parenteral administration of the drug.{3387}
Brand:CaymanSKU:- 16-phenoxy tetranor PGE2 is the free acid form of sulprostone formed by the hydrolysis of the methylsulfonamide bond.{3387} 16-phenoxy tetranor PGE2 is a minor metabolite of sulprostone found in human plasma after parenteral administration of the drug.{3387}
Brand:CaymanSKU:- 16-phenoxy tetranor PGE2 is the free acid form of sulprostone formed by the hydrolysis of the methylsulfonamide bond.{3387} 16-phenoxy tetranor PGE2 is a minor metabolite of sulprostone found in human plasma after parenteral administration of the drug.{3387}
Brand:CaymanSKU:-
16-phenoxy PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.{2058}
Brand:CaymanSKU:-Out of stock
16-phenoxy PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.{2058}
Brand:CaymanSKU:-Out of stock
16-phenoxy PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.{2058}
Brand:CaymanSKU:-Out of stock
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α isopropyl ester (16-phenoxy tetranor PGF2α isopropyl ester) is a lipophilic analog of 16-phenoxy tetranor PGF2α. Isopropyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
Brand:CaymanSKU:10010103 - 1 mgAvailable on backorder
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α isopropyl ester (16-phenoxy tetranor PGF2α isopropyl ester) is a lipophilic analog of 16-phenoxy tetranor PGF2α. Isopropyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
Brand:CaymanSKU:10010103 - 10 mgAvailable on backorder
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α isopropyl ester (16-phenoxy tetranor PGF2α isopropyl ester) is a lipophilic analog of 16-phenoxy tetranor PGF2α. Isopropyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
Brand:CaymanSKU:10010103 - 5 mgAvailable on backorder
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α isopropyl ester (16-phenoxy tetranor PGF2α isopropyl ester) is a lipophilic analog of 16-phenoxy tetranor PGF2α. Isopropyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
Brand:CaymanSKU:10010103 - 500 µgAvailable on backorder
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α (16-phenoxy tetranor PGF2α) is a metabolically stable form of PGF2α containing a 16-phenoxy group at the ω-terminus. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.{2058} 16-phenoxy tetranor PGF2α methyl ester is a lipophilic analog of 16-phenoxy tetranor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
Brand:CaymanSKU:10010102 - 1 mgAvailable on backorder
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α (16-phenoxy tetranor PGF2α) is a metabolically stable form of PGF2α containing a 16-phenoxy group at the ω-terminus. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.{2058} 16-phenoxy tetranor PGF2α methyl ester is a lipophilic analog of 16-phenoxy tetranor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
Brand:CaymanSKU:10010102 - 5 mgAvailable on backorder