Cayman
Showing 37651–37800 of 45550 results
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Brand:CaymanSKU:400382 - 500 dtnAvailable on backorder
Cayman’s Resolvin D1 (RvD1) ELISA Kit is a competitive assay that can be used for quantification of RvD1 (17(S)-Resolvin D1) in plasma, serum, and cell culture supernatants. The assay has a range from 3.3-2,000 pg/ml and a sensitivity (80% B/B0) of approximately 15 pg/ml.
Brand:CaymanSKU:500380 - 480 solid wellsAvailable on backorder
Cayman’s Resolvin D1 (RvD1) ELISA Kit is a competitive assay that can be used for quantification of RvD1 (17(S)-Resolvin D1) in plasma, serum, and cell culture supernatants. The assay has a range from 3.3-2,000 pg/ml and a sensitivity (80% B/B0) of approximately 15 pg/ml.
Brand:CaymanSKU:500380 - 480 strip wellsAvailable on backorder
Cayman’s Resolvin D1 (RvD1) ELISA Kit is a competitive assay that can be used for quantification of RvD1 (17(S)-Resolvin D1) in plasma, serum, and cell culture supernatants. The assay has a range from 3.3-2,000 pg/ml and a sensitivity (80% B/B0) of approximately 15 pg/ml.
Brand:CaymanSKU:500380 - 96 solid wellsAvailable on backorder
Cayman’s Resolvin D1 (RvD1) ELISA Kit is a competitive assay that can be used for quantification of RvD1 (17(S)-Resolvin D1) in plasma, serum, and cell culture supernatants. The assay has a range from 3.3-2,000 pg/ml and a sensitivity (80% B/B0) of approximately 15 pg/ml.
Brand:CaymanSKU:500380 - 96 strip wellsAvailable on backorder
Brand:CaymanSKU:400384 - 100 ngAvailable on backorder
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.{14973} Resolvin D1 (RvD1) is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase.{13989} A 17(R)-epimer (Item No. 13060) of RvD1 can also be generated in aspirin-treated samples.{11433} Both RvD1 and its 17(R)-configuration reduce human polymorphonuclear leukocyte (PMNL) transendothelial migration, the earliest event in acute inflammation, with EC50 values of ~30 nM.{15718} RvD1 and its aspirin-triggered form also exhibit a dose-dependent reduction in leukocyte infiltration in a mouse model of peritonitis with a maximal inhibition of ~35% at a 10-100 ng dose.{15718} Analytical and biological comparisons of synthetic RvD1 with endogenously derived RvD1 have confirmed its identity as matching the natural product.{14569} RvD1 MaxSpec® standard is a quantitative grade standard of RvD1 (Item No. 10012554) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This RvD1 MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Brand:CaymanSKU:25905 - 10 µgAvailable on backorder
Resolvin D1 (RvD1; Item No. 10012554) is produced physiologically from the sequential oxygenation of docosahexaenoic acid (Item No. 90310) by 15- and 5-lipoxygenase (Item No. 60402).{13989} It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with an EC50 value of ~30 nM.{15718} RvD1 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.
Brand:CaymanSKU:9001815 - 10 µgAvailable on backorder
Resolvin D1 (RvD1; Item No. 10012554) is produced physiologically from the sequential oxygenation of docosahexaenoic acid (Item No. 90310) by 15- and 5-lipoxygenase (Item No. 60402).{13989} It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with an EC50 value of ~30 nM.{15718} RvD1 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.
Brand:CaymanSKU:9001815 - 100 µgAvailable on backorder
Resolvin D1 (RvD1; Item No. 10012554) is produced physiologically from the sequential oxygenation of docosahexaenoic acid (Item No. 90310) by 15- and 5-lipoxygenase (Item No. 60402).{13989} It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with an EC50 value of ~30 nM.{15718} RvD1 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.
Brand:CaymanSKU:9001815 - 25 µgAvailable on backorder
Resolvin D1 (RvD1; Item No. 10012554) is produced physiologically from the sequential oxygenation of docosahexaenoic acid (Item No. 90310) by 15- and 5-lipoxygenase (Item No. 60402).{13989} It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with an EC50 value of ~30 nM.{15718} RvD1 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.
Brand:CaymanSKU:9001815 - 50 µgAvailable on backorder
Resolvin D1-d5 (RvD1-d5) is intended for use as an internal standard for the quantification of RvD1 (Item No. 10012554) by GC- or LC-mass spectrometry. Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.{14973} RvD1 is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase.{13989} A 17(R)-epimer of RvD1 can also be generated in aspirin-treated samples.{11433} Both RvD1 and its 17(R) configuration reduce human polymorphonuclear leukocyte (PMNL) transendothelial migration, the earliest event in acute inflammation, with EC50 values of ~30 nM.{15718} RvD1 and its aspirin-triggered form also exhibit a dose-dependent reduction in leukocyte infiltration in a mouse model of peritonitis with a maximal inhibition of ~35% at a 10-100 ng dose.{15718}
Brand:CaymanSKU:11182 - 10 µgAvailable on backorder
Resolvin D1-d5 (RvD1-d5) is intended for use as an internal standard for the quantification of RvD1 (Item No. 10012554) by GC- or LC-mass spectrometry. Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.{14973} RvD1 is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase.{13989} A 17(R)-epimer of RvD1 can also be generated in aspirin-treated samples.{11433} Both RvD1 and its 17(R) configuration reduce human polymorphonuclear leukocyte (PMNL) transendothelial migration, the earliest event in acute inflammation, with EC50 values of ~30 nM.{15718} RvD1 and its aspirin-triggered form also exhibit a dose-dependent reduction in leukocyte infiltration in a mouse model of peritonitis with a maximal inhibition of ~35% at a 10-100 ng dose.{15718}
Brand:CaymanSKU:11182 - 25 µgAvailable on backorder
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.{14973} Resolvin D2 (RvD2) is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase and functions to dampen excessive neutrophil trafficking to sites of inflammation.{18209} It reduces zymosan-stimulated PMN infiltration by 70% at doses as low as 10 pg per mouse and significantly reduces PAF-stimulated leukocyte adherence and emigration at 1 nM.{18209} Also, by stimulating nitric oxide production, RvD2 dose dependently decreases leukocyte-endothelial interactions. In a mouse model of sepsis, RvD2 reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance.{18209} Analytical and biological comparisons of synthetic RvD2 with endogenously derived RvD2 have confirmed its identity as matching the natural product.{14569}
Brand:CaymanSKU:10007279 - 10 µgAvailable on backorder
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.{14973} Resolvin D2 (RvD2) is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase and functions to dampen excessive neutrophil trafficking to sites of inflammation.{18209} It reduces zymosan-stimulated PMN infiltration by 70% at doses as low as 10 pg per mouse and significantly reduces PAF-stimulated leukocyte adherence and emigration at 1 nM.{18209} Also, by stimulating nitric oxide production, RvD2 dose dependently decreases leukocyte-endothelial interactions. In a mouse model of sepsis, RvD2 reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance.{18209} Analytical and biological comparisons of synthetic RvD2 with endogenously derived RvD2 have confirmed its identity as matching the natural product.{14569}
Brand:CaymanSKU:10007279 - 100 µgAvailable on backorder
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.{14973} Resolvin D2 (RvD2) is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase and functions to dampen excessive neutrophil trafficking to sites of inflammation.{18209} It reduces zymosan-stimulated PMN infiltration by 70% at doses as low as 10 pg per mouse and significantly reduces PAF-stimulated leukocyte adherence and emigration at 1 nM.{18209} Also, by stimulating nitric oxide production, RvD2 dose dependently decreases leukocyte-endothelial interactions. In a mouse model of sepsis, RvD2 reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance.{18209} Analytical and biological comparisons of synthetic RvD2 with endogenously derived RvD2 have confirmed its identity as matching the natural product.{14569}
Brand:CaymanSKU:10007279 - 25 µgAvailable on backorder
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.{14973} Resolvin D2 (RvD2) is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase and functions to dampen excessive neutrophil trafficking to sites of inflammation.{18209} It reduces zymosan-stimulated PMN infiltration by 70% at doses as low as 10 pg per mouse and significantly reduces PAF-stimulated leukocyte adherence and emigration at 1 nM.{18209} Also, by stimulating nitric oxide production, RvD2 dose dependently decreases leukocyte-endothelial interactions. In a mouse model of sepsis, RvD2 reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance.{18209} Analytical and biological comparisons of synthetic RvD2 with endogenously derived RvD2 have confirmed its identity as matching the natural product.{14569}
Brand:CaymanSKU:10007279 - 50 µgAvailable on backorder
Brand:CaymanSKU:401122 - 100 dtnAvailable on backorder
Brand:CaymanSKU:401122 - 500 dtnAvailable on backorder
Resolvin D2 (RvD2) is produced physiologically from the sequential oxygenation of docosahexaenoic acid (DHA) by 15- and 5-lipoxygenases. RvD2 reduces polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, by ~70% at doses as low as 10 pg in the mouse model of peritonitis. In the rat model of burn injury and sepsis, RvD2 restores defective neutrophil motility and dramatically increases survival at doses of 8-10 ng/rat. Resolvins also enhance bacterial clearance by phagocytosis and have been shown to synergistically enhance certain antibiotics. Cayman’s Resolvin D2 ELISA Kit is a competitive assay that can be used for quantification of RvD2. Due to the number and variation of potential sample types, this assay has been validated in Cayman’s ELISA Buffer (Item No. 400060) diluted to 1X (0.1 M potassium phosphate containing 0.1% BSA, 400 mM sodium chloride, 1 mM EDTA, and 0.01% sodium azide), human plasma, and human serum. The assay has a range from 1.6-1,000 pg/ml and a sensitivity (80% B/B0) of approximately 10 pg/ml.
Brand:CaymanSKU:501120 - 480 solid wellsAvailable on backorder
Resolvin D2 (RvD2) is produced physiologically from the sequential oxygenation of docosahexaenoic acid (DHA) by 15- and 5-lipoxygenases. RvD2 reduces polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, by ~70% at doses as low as 10 pg in the mouse model of peritonitis. In the rat model of burn injury and sepsis, RvD2 restores defective neutrophil motility and dramatically increases survival at doses of 8-10 ng/rat. Resolvins also enhance bacterial clearance by phagocytosis and have been shown to synergistically enhance certain antibiotics. Cayman’s Resolvin D2 ELISA Kit is a competitive assay that can be used for quantification of RvD2. Due to the number and variation of potential sample types, this assay has been validated in Cayman’s ELISA Buffer (Item No. 400060) diluted to 1X (0.1 M potassium phosphate containing 0.1% BSA, 400 mM sodium chloride, 1 mM EDTA, and 0.01% sodium azide), human plasma, and human serum. The assay has a range from 1.6-1,000 pg/ml and a sensitivity (80% B/B0) of approximately 10 pg/ml.
Brand:CaymanSKU:501120 - 480 strip wellsAvailable on backorder
Resolvin D2 (RvD2) is produced physiologically from the sequential oxygenation of docosahexaenoic acid (DHA) by 15- and 5-lipoxygenases. RvD2 reduces polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, by ~70% at doses as low as 10 pg in the mouse model of peritonitis. In the rat model of burn injury and sepsis, RvD2 restores defective neutrophil motility and dramatically increases survival at doses of 8-10 ng/rat. Resolvins also enhance bacterial clearance by phagocytosis and have been shown to synergistically enhance certain antibiotics. Cayman’s Resolvin D2 ELISA Kit is a competitive assay that can be used for quantification of RvD2. Due to the number and variation of potential sample types, this assay has been validated in Cayman’s ELISA Buffer (Item No. 400060) diluted to 1X (0.1 M potassium phosphate containing 0.1% BSA, 400 mM sodium chloride, 1 mM EDTA, and 0.01% sodium azide), human plasma, and human serum. The assay has a range from 1.6-1,000 pg/ml and a sensitivity (80% B/B0) of approximately 10 pg/ml.
Brand:CaymanSKU:501120 - 96 solid wellsAvailable on backorder
Resolvin D2 (RvD2) is produced physiologically from the sequential oxygenation of docosahexaenoic acid (DHA) by 15- and 5-lipoxygenases. RvD2 reduces polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, by ~70% at doses as low as 10 pg in the mouse model of peritonitis. In the rat model of burn injury and sepsis, RvD2 restores defective neutrophil motility and dramatically increases survival at doses of 8-10 ng/rat. Resolvins also enhance bacterial clearance by phagocytosis and have been shown to synergistically enhance certain antibiotics. Cayman’s Resolvin D2 ELISA Kit is a competitive assay that can be used for quantification of RvD2. Due to the number and variation of potential sample types, this assay has been validated in Cayman’s ELISA Buffer (Item No. 400060) diluted to 1X (0.1 M potassium phosphate containing 0.1% BSA, 400 mM sodium chloride, 1 mM EDTA, and 0.01% sodium azide), human plasma, and human serum. The assay has a range from 1.6-1,000 pg/ml and a sensitivity (80% B/B0) of approximately 10 pg/ml.
Brand:CaymanSKU:501120 - 96 strip wellsAvailable on backorder
Brand:CaymanSKU:401124 - 50 ngAvailable on backorder
Resolvin D2 (RvD2) (Item No. 10007279) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase.{20052} It evokes diverse anti-inflammatory effects which may mediate the resolution of inflammation.{19640,18209} RvD2 methyl ester is a methyl ester version of the free acid which may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.
Brand:CaymanSKU:9001497 - 10 µgAvailable on backorder
Resolvin D2 (RvD2) (Item No. 10007279) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase.{20052} It evokes diverse anti-inflammatory effects which may mediate the resolution of inflammation.{19640,18209} RvD2 methyl ester is a methyl ester version of the free acid which may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.
Brand:CaymanSKU:9001497 - 100 µgAvailable on backorder
Resolvin D2 (RvD2) (Item No. 10007279) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase.{20052} It evokes diverse anti-inflammatory effects which may mediate the resolution of inflammation.{19640,18209} RvD2 methyl ester is a methyl ester version of the free acid which may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.
Brand:CaymanSKU:9001497 - 25 µgAvailable on backorder
Resolvin D2 (RvD2) (Item No. 10007279) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase.{20052} It evokes diverse anti-inflammatory effects which may mediate the resolution of inflammation.{19640,18209} RvD2 methyl ester is a methyl ester version of the free acid which may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.
Brand:CaymanSKU:9001497 - 50 µgAvailable on backorder
Resolvin D2-d5 (RvD2-d5) is intended for use as an internal standard for the quantification of resolvin D2 (Item No. 10007279) by GC- or LC-MS. Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.{14973} Resolvin D2 is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase and functions to dampen excessive neutrophil trafficking to sites of inflammation.{18209} It reduces zymosan-stimulated PMN infiltration by 70% at doses as low as 10 pg per mouse and significantly reduces PAF-stimulated leukocyte adherence and emigration at 1 nM.{18209} Also, by stimulating nitric oxide production, resolvin D2 dose dependently decreases leukocyte-endothelial interactions. In a murine model of sepsis, resolvin D2 reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance.{18209}
Brand:CaymanSKU:11184 - 10 µgAvailable on backorder
Resolvin D2-d5 (RvD2-d5) is intended for use as an internal standard for the quantification of resolvin D2 (Item No. 10007279) by GC- or LC-MS. Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.{14973} Resolvin D2 is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase and functions to dampen excessive neutrophil trafficking to sites of inflammation.{18209} It reduces zymosan-stimulated PMN infiltration by 70% at doses as low as 10 pg per mouse and significantly reduces PAF-stimulated leukocyte adherence and emigration at 1 nM.{18209} Also, by stimulating nitric oxide production, resolvin D2 dose dependently decreases leukocyte-endothelial interactions. In a murine model of sepsis, resolvin D2 reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance.{18209}
Brand:CaymanSKU:11184 - 25 µgAvailable on backorder
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response.{14973} Resolvin D3 (RvD3) is a DHA-derived product first identified in mouse inflammatory exudates.{11433} It reduces neutrophil infiltration in vivo in both mouse peritonitis and dermal inflammation.{11433} In addition to suppressing leukocyte migration, RvD3 enhances macrophage phagocytosis and efferocytosis.{29714} Unlike other resolvins, RvD3 appears late in resolution in mouse peritonitis.{29714,29715} Analytical and biological comparisons of synthetic RvD3 with endogenously derived RvD3 have confirmed its identity as matching the natural product.{14569}
Brand:CaymanSKU:- Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response.{14973} Resolvin D3 (RvD3) is a DHA-derived product first identified in mouse inflammatory exudates.{11433} It reduces neutrophil infiltration in vivo in both mouse peritonitis and dermal inflammation.{11433} In addition to suppressing leukocyte migration, RvD3 enhances macrophage phagocytosis and efferocytosis.{29714} Unlike other resolvins, RvD3 appears late in resolution in mouse peritonitis.{29714,29715} Analytical and biological comparisons of synthetic RvD3 with endogenously derived RvD3 have confirmed its identity as matching the natural product.{14569}
Brand:CaymanSKU:- Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response.{14973} Resolvin D3 (RvD3) is a DHA-derived product first identified in mouse inflammatory exudates.{11433} It reduces neutrophil infiltration in vivo in both mouse peritonitis and dermal inflammation.{11433} In addition to suppressing leukocyte migration, RvD3 enhances macrophage phagocytosis and efferocytosis.{29714} Unlike other resolvins, RvD3 appears late in resolution in mouse peritonitis.{29714,29715} Analytical and biological comparisons of synthetic RvD3 with endogenously derived RvD3 have confirmed its identity as matching the natural product.{14569}
Brand:CaymanSKU:- Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response.{14973} Resolvin D3 (RvD3) is a DHA-derived product first identified in mouse inflammatory exudates.{11433} It reduces neutrophil infiltration in vivo in both mouse peritonitis and dermal inflammation.{11433} In addition to suppressing leukocyte migration, RvD3 enhances macrophage phagocytosis and efferocytosis.{29714} Unlike other resolvins, RvD3 appears late in resolution in mouse peritonitis.{29714,29715} Analytical and biological comparisons of synthetic RvD3 with endogenously derived RvD3 have confirmed its identity as matching the natural product.{14569}
Brand:CaymanSKU:-
Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid (Item No. 90310).{18022} It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines.{32237,30353} RvD4, at 10 ng/mouse, reduces neutrophil infiltration in zymosan A-induced peritonitis and, at 200 ng/mouse, diminishes neutrophil infiltration in response to S. aureus infection.{30353} With isolated cells, RvD4 promotes phagocytosis of bacteria, opsonized zymosan A, and apoptotic neutrophils by human macrophages.{30353} It also promotes the clearance of apoptotic neutrophils by human fibroblasts.{30353}
Brand:CaymanSKU:- Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid (Item No. 90310).{18022} It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines.{32237,30353} RvD4, at 10 ng/mouse, reduces neutrophil infiltration in zymosan A-induced peritonitis and, at 200 ng/mouse, diminishes neutrophil infiltration in response to S. aureus infection.{30353} With isolated cells, RvD4 promotes phagocytosis of bacteria, opsonized zymosan A, and apoptotic neutrophils by human macrophages.{30353} It also promotes the clearance of apoptotic neutrophils by human fibroblasts.{30353}
Brand:CaymanSKU:- Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid (Item No. 90310).{18022} It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines.{32237,30353} RvD4, at 10 ng/mouse, reduces neutrophil infiltration in zymosan A-induced peritonitis and, at 200 ng/mouse, diminishes neutrophil infiltration in response to S. aureus infection.{30353} With isolated cells, RvD4 promotes phagocytosis of bacteria, opsonized zymosan A, and apoptotic neutrophils by human macrophages.{30353} It also promotes the clearance of apoptotic neutrophils by human fibroblasts.{30353}
Brand:CaymanSKU:- Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid (Item No. 90310).{18022} It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines.{32237,30353} RvD4, at 10 ng/mouse, reduces neutrophil infiltration in zymosan A-induced peritonitis and, at 200 ng/mouse, diminishes neutrophil infiltration in response to S. aureus infection.{30353} With isolated cells, RvD4 promotes phagocytosis of bacteria, opsonized zymosan A, and apoptotic neutrophils by human macrophages.{30353} It also promotes the clearance of apoptotic neutrophils by human fibroblasts.{30353}
Brand:CaymanSKU:- Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid (Item No. 90310).{18022} It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines.{32237,30353} RvD4, at 10 ng/mouse, reduces neutrophil infiltration in zymosan A-induced peritonitis and, at 200 ng/mouse, diminishes neutrophil infiltration in response to S. aureus infection.{30353} With isolated cells, RvD4 promotes phagocytosis of bacteria, opsonized zymosan A, and apoptotic neutrophils by human macrophages.{30353} It also promotes the clearance of apoptotic neutrophils by human fibroblasts.{30353}
Brand:CaymanSKU:- Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid (Item No. 90310).{18022} It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines.{32237,30353} RvD4, at 10 ng/mouse, reduces neutrophil infiltration in zymosan A-induced peritonitis and, at 200 ng/mouse, diminishes neutrophil infiltration in response to S. aureus infection.{30353} With isolated cells, RvD4 promotes phagocytosis of bacteria, opsonized zymosan A, and apoptotic neutrophils by human macrophages.{30353} It also promotes the clearance of apoptotic neutrophils by human fibroblasts.{30353}
Brand:CaymanSKU:-
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.{14973} Resolvin D5 (RvD5) is a DHA-derived resolvin generated by a double dioxygenation mechanism.{14974} RvD5 has been identified in media from ionophore-stimulated trout brain cells, in human synovial fluid from patients with rheumatoid arthritis, and in exudates of bacterial infections in mice.{15180,30501,30500} RvD5 stimulates the phagocytosis of E. coli by human macrophages, and RvD5 methyl ester enhances bacterial killing in mice inoculated with E. coli.{30500} Analytical and biological comparisons of synthetic RvD5 with endogenously derived RvD5 have confirmed its identity as matching the natural product.{14569}
Brand:CaymanSKU:10007280 - 10 µgAvailable on backorder
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.{14973} Resolvin D5 (RvD5) is a DHA-derived resolvin generated by a double dioxygenation mechanism.{14974} RvD5 has been identified in media from ionophore-stimulated trout brain cells, in human synovial fluid from patients with rheumatoid arthritis, and in exudates of bacterial infections in mice.{15180,30501,30500} RvD5 stimulates the phagocytosis of E. coli by human macrophages, and RvD5 methyl ester enhances bacterial killing in mice inoculated with E. coli.{30500} Analytical and biological comparisons of synthetic RvD5 with endogenously derived RvD5 have confirmed its identity as matching the natural product.{14569}
Brand:CaymanSKU:10007280 - 100 µgAvailable on backorder
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.{14973} Resolvin D5 (RvD5) is a DHA-derived resolvin generated by a double dioxygenation mechanism.{14974} RvD5 has been identified in media from ionophore-stimulated trout brain cells, in human synovial fluid from patients with rheumatoid arthritis, and in exudates of bacterial infections in mice.{15180,30501,30500} RvD5 stimulates the phagocytosis of E. coli by human macrophages, and RvD5 methyl ester enhances bacterial killing in mice inoculated with E. coli.{30500} Analytical and biological comparisons of synthetic RvD5 with endogenously derived RvD5 have confirmed its identity as matching the natural product.{14569}
Brand:CaymanSKU:10007280 - 25 µgAvailable on backorder
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310).{13989} In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state.{14973} Resolvin D5 (RvD5) is a DHA-derived resolvin generated by a double dioxygenation mechanism.{14974} RvD5 has been identified in media from ionophore-stimulated trout brain cells, in human synovial fluid from patients with rheumatoid arthritis, and in exudates of bacterial infections in mice.{15180,30501,30500} RvD5 stimulates the phagocytosis of E. coli by human macrophages, and RvD5 methyl ester enhances bacterial killing in mice inoculated with E. coli.{30500} Analytical and biological comparisons of synthetic RvD5 with endogenously derived RvD5 have confirmed its identity as matching the natural product.{14569}
Brand:CaymanSKU:10007280 - 50 µgAvailable on backorder
Resolvin E1 (RvE1) is a trihydroxy eicosapentaenoic acid (EPA; Item No. 90110) metabolite that has been identified in mouse inflammatory exudates and in human plasma when subjects are treated with both aspirin (Item No. 70260) and supplemental EPA.{21162,11433,13210} RvE1 is an anti-inflammatory EPA metabolite that has been shown to promote inflammatory resolution in numerous disease models, including experimental colitis, asthma, atherosclerosis, type 2 diabetes, and HSV-1-induced stromal keratitis.{14504,13209,15876,30594,30592,30593,30595,30596}
Brand:CaymanSKU:10007848 - 10 µgAvailable on backorder
Resolvin E1 (RvE1) is a trihydroxy eicosapentaenoic acid (EPA; Item No. 90110) metabolite that has been identified in mouse inflammatory exudates and in human plasma when subjects are treated with both aspirin (Item No. 70260) and supplemental EPA.{21162,11433,13210} RvE1 is an anti-inflammatory EPA metabolite that has been shown to promote inflammatory resolution in numerous disease models, including experimental colitis, asthma, atherosclerosis, type 2 diabetes, and HSV-1-induced stromal keratitis.{14504,13209,15876,30594,30592,30593,30595,30596}
Brand:CaymanSKU:10007848 - 100 µgAvailable on backorder
Resolvin E1 (RvE1) is a trihydroxy eicosapentaenoic acid (EPA; Item No. 90110) metabolite that has been identified in mouse inflammatory exudates and in human plasma when subjects are treated with both aspirin (Item No. 70260) and supplemental EPA.{21162,11433,13210} RvE1 is an anti-inflammatory EPA metabolite that has been shown to promote inflammatory resolution in numerous disease models, including experimental colitis, asthma, atherosclerosis, type 2 diabetes, and HSV-1-induced stromal keratitis.{14504,13209,15876,30594,30592,30593,30595,30596}
Brand:CaymanSKU:10007848 - 25 µgAvailable on backorder
Resolvin E1 (RvE1) is a trihydroxy eicosapentaenoic acid (EPA; Item No. 90110) metabolite that has been identified in mouse inflammatory exudates and in human plasma when subjects are treated with both aspirin (Item No. 70260) and supplemental EPA.{21162,11433,13210} RvE1 is an anti-inflammatory EPA metabolite that has been shown to promote inflammatory resolution in numerous disease models, including experimental colitis, asthma, atherosclerosis, type 2 diabetes, and HSV-1-induced stromal keratitis.{14504,13209,15876,30594,30592,30593,30595,30596}
Brand:CaymanSKU:10007848 - 50 µgAvailable on backorder
Resolvin E4 (RvE4) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.{50723} It is produced from eicosapentaenoic acid (EPA; Item Nos. 90110 | 90110.1 | 21908) by 15-lipoxygenase (15-LO) via 15(S)-HpEPE (Item No. 42710) and 15S-hydroxy, 5S-HpEPE intermediates in vitro and by isolated human M2 macrophages or polymorphonuclear (PMN) neutrophils under normoxic or hypoxic conditions. RvE4 synthesis is enhanced in M2 macrophage and neutrophil co-cultures, indicating transcellular biosynthesis by a potential 15-LO and 5-LO mechanism. It has been found in mouse inflammatory exudates. RvE4 (10 nM) increases efferocytosis of apoptotic neutrophils or senescent red blood cells (sRBCs) by human M2 macrophages under hypoxic conditions in vitro. Intraperitoneal administration of RvE4 (100 ng/animal) inhibits increases in inflammatory exudate neutrophil infiltration in a mouse model of hemorrhagic peritonitis induced by zymosan A (Item No. 21175) and thrombin. It also increases inflammatory exudate macrophage infiltration and efferocytosis of apoptotic neutrophils and/or RBCs in the same model.
Brand:CaymanSKU:29590 - 10 µgAvailable on backorder
Resolvin E4 (RvE4) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.{50723} It is produced from eicosapentaenoic acid (EPA; Item Nos. 90110 | 90110.1 | 21908) by 15-lipoxygenase (15-LO) via 15(S)-HpEPE (Item No. 42710) and 15S-hydroxy, 5S-HpEPE intermediates in vitro and by isolated human M2 macrophages or polymorphonuclear (PMN) neutrophils under normoxic or hypoxic conditions. RvE4 synthesis is enhanced in M2 macrophage and neutrophil co-cultures, indicating transcellular biosynthesis by a potential 15-LO and 5-LO mechanism. It has been found in mouse inflammatory exudates. RvE4 (10 nM) increases efferocytosis of apoptotic neutrophils or senescent red blood cells (sRBCs) by human M2 macrophages under hypoxic conditions in vitro. Intraperitoneal administration of RvE4 (100 ng/animal) inhibits increases in inflammatory exudate neutrophil infiltration in a mouse model of hemorrhagic peritonitis induced by zymosan A (Item No. 21175) and thrombin. It also increases inflammatory exudate macrophage infiltration and efferocytosis of apoptotic neutrophils and/or RBCs in the same model.
Brand:CaymanSKU:29590 - 100 µgAvailable on backorder
Resolvin E4 (RvE4) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.{50723} It is produced from eicosapentaenoic acid (EPA; Item Nos. 90110 | 90110.1 | 21908) by 15-lipoxygenase (15-LO) via 15(S)-HpEPE (Item No. 42710) and 15S-hydroxy, 5S-HpEPE intermediates in vitro and by isolated human M2 macrophages or polymorphonuclear (PMN) neutrophils under normoxic or hypoxic conditions. RvE4 synthesis is enhanced in M2 macrophage and neutrophil co-cultures, indicating transcellular biosynthesis by a potential 15-LO and 5-LO mechanism. It has been found in mouse inflammatory exudates. RvE4 (10 nM) increases efferocytosis of apoptotic neutrophils or senescent red blood cells (sRBCs) by human M2 macrophages under hypoxic conditions in vitro. Intraperitoneal administration of RvE4 (100 ng/animal) inhibits increases in inflammatory exudate neutrophil infiltration in a mouse model of hemorrhagic peritonitis induced by zymosan A (Item No. 21175) and thrombin. It also increases inflammatory exudate macrophage infiltration and efferocytosis of apoptotic neutrophils and/or RBCs in the same model.
Brand:CaymanSKU:29590 - 25 µgAvailable on backorder
Resolvin E4 (RvE4) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.{50723} It is produced from eicosapentaenoic acid (EPA; Item Nos. 90110 | 90110.1 | 21908) by 15-lipoxygenase (15-LO) via 15(S)-HpEPE (Item No. 42710) and 15S-hydroxy, 5S-HpEPE intermediates in vitro and by isolated human M2 macrophages or polymorphonuclear (PMN) neutrophils under normoxic or hypoxic conditions. RvE4 synthesis is enhanced in M2 macrophage and neutrophil co-cultures, indicating transcellular biosynthesis by a potential 15-LO and 5-LO mechanism. It has been found in mouse inflammatory exudates. RvE4 (10 nM) increases efferocytosis of apoptotic neutrophils or senescent red blood cells (sRBCs) by human M2 macrophages under hypoxic conditions in vitro. Intraperitoneal administration of RvE4 (100 ng/animal) inhibits increases in inflammatory exudate neutrophil infiltration in a mouse model of hemorrhagic peritonitis induced by zymosan A (Item No. 21175) and thrombin. It also increases inflammatory exudate macrophage infiltration and efferocytosis of apoptotic neutrophils and/or RBCs in the same model.
Brand:CaymanSKU:29590 - 50 µgAvailable on backorder
Angiotensin-converting enzyme 2 (ACE2) is an enzyme that is cardioprotective and renoprotective. Resorcinolnaphthalein increases the activity of ACE2 in vitro (EC50 = 19.5 μM).{16242} Activation of ACE2 in rats produces a decrease in blood pressure and improvement in cardiac function. In spontaneously hypertensive rats it produces a reversal of myocardial, perivascular, and renal fibrosis.{16242}
Brand:CaymanSKU:- Angiotensin-converting enzyme 2 (ACE2) is an enzyme that is cardioprotective and renoprotective. Resorcinolnaphthalein increases the activity of ACE2 in vitro (EC50 = 19.5 μM).{16242} Activation of ACE2 in rats produces a decrease in blood pressure and improvement in cardiac function. In spontaneously hypertensive rats it produces a reversal of myocardial, perivascular, and renal fibrosis.{16242}
Brand:CaymanSKU:- Angiotensin-converting enzyme 2 (ACE2) is an enzyme that is cardioprotective and renoprotective. Resorcinolnaphthalein increases the activity of ACE2 in vitro (EC50 = 19.5 μM).{16242} Activation of ACE2 in rats produces a decrease in blood pressure and improvement in cardiac function. In spontaneously hypertensive rats it produces a reversal of myocardial, perivascular, and renal fibrosis.{16242}
Brand:CaymanSKU:- Angiotensin-converting enzyme 2 (ACE2) is an enzyme that is cardioprotective and renoprotective. Resorcinolnaphthalein increases the activity of ACE2 in vitro (EC50 = 19.5 μM).{16242} Activation of ACE2 in rats produces a decrease in blood pressure and improvement in cardiac function. In spontaneously hypertensive rats it produces a reversal of myocardial, perivascular, and renal fibrosis.{16242}
Brand:CaymanSKU:-
Resorufin is a fluorescent probe and the reduced form of the redox indicator dye resazurin (Item No. 14322).{22811} It can be further reduced to hydroresorufin, which is non-fluorescent. Resorufin has been used in the synthesis of resorufin-based fluorescent probes.{53819,58113} It has also been used for the direct measurement of solvent-solute hydrogen bond dynamics with distinct absorption and emission peaks in solvents with strong hydrogen bonds and overlapping peaks in solvents with weak hydrogen bonds.{58114} It displays excitation/emission maxima of 570/580 nm, respectively.
Brand:CaymanSKU:30789 - 1 gAvailable on backorder
Resorufin is a fluorescent probe and the reduced form of the redox indicator dye resazurin (Item No. 14322).{22811} It can be further reduced to hydroresorufin, which is non-fluorescent. Resorufin has been used in the synthesis of resorufin-based fluorescent probes.{53819,58113} It has also been used for the direct measurement of solvent-solute hydrogen bond dynamics with distinct absorption and emission peaks in solvents with strong hydrogen bonds and overlapping peaks in solvents with weak hydrogen bonds.{58114} It displays excitation/emission maxima of 570/580 nm, respectively.
Brand:CaymanSKU:30789 - 100 mgAvailable on backorder
Resorufin is a fluorescent probe and the reduced form of the redox indicator dye resazurin (Item No. 14322).{22811} It can be further reduced to hydroresorufin, which is non-fluorescent. Resorufin has been used in the synthesis of resorufin-based fluorescent probes.{53819,58113} It has also been used for the direct measurement of solvent-solute hydrogen bond dynamics with distinct absorption and emission peaks in solvents with strong hydrogen bonds and overlapping peaks in solvents with weak hydrogen bonds.{58114} It displays excitation/emission maxima of 570/580 nm, respectively.
Brand:CaymanSKU:30789 - 250 mgAvailable on backorder
Resorufin is a fluorescent probe and the reduced form of the redox indicator dye resazurin (Item No. 14322).{22811} It can be further reduced to hydroresorufin, which is non-fluorescent. Resorufin has been used in the synthesis of resorufin-based fluorescent probes.{53819,58113} It has also been used for the direct measurement of solvent-solute hydrogen bond dynamics with distinct absorption and emission peaks in solvents with strong hydrogen bonds and overlapping peaks in solvents with weak hydrogen bonds.{58114} It displays excitation/emission maxima of 570/580 nm, respectively.
Brand:CaymanSKU:30789 - 500 mgAvailable on backorder
Resorufin acetate is a fluorometric probe that acts as a substrate for cytosolic aldehyde dehydrogenase (ALDH1A1) esterase activity.{34121} It is also a useful substrate for chymotrypsin.{34122} Upon enzymatic cleavage, the resorufin anion displays red fluorescence (ex/em maxima = 570/580 nm, respectively).{50356}
Brand:CaymanSKU:21686 -Out of stock
Resorufin acetate is a fluorometric probe that acts as a substrate for cytosolic aldehyde dehydrogenase (ALDH1A1) esterase activity.{34121} It is also a useful substrate for chymotrypsin.{34122} Upon enzymatic cleavage, the resorufin anion displays red fluorescence (ex/em maxima = 570/580 nm, respectively).{50356}
Brand:CaymanSKU:21686 -Out of stock
Resorufin acetate is a fluorometric probe that acts as a substrate for cytosolic aldehyde dehydrogenase (ALDH1A1) esterase activity.{34121} It is also a useful substrate for chymotrypsin.{34122} Upon enzymatic cleavage, the resorufin anion displays red fluorescence (ex/em maxima = 570/580 nm, respectively).{50356}
Brand:CaymanSKU:21686 -Out of stock
Resorufin acetate is a fluorometric probe that acts as a substrate for cytosolic aldehyde dehydrogenase (ALDH1A1) esterase activity.{34121} It is also a useful substrate for chymotrypsin.{34122} Upon enzymatic cleavage, the resorufin anion displays red fluorescence (ex/em maxima = 570/580 nm, respectively).{50356}
Brand:CaymanSKU:21686 -Out of stock
Resorufin butyrate is a fluorogenic substrate for triglyceride lipases.{31903} It is also a substrate for cholinesterase.{31902} Upon enzymatic cleavage by triglyceride lipases or cholinesterase, resorufin is released and can be used to quantify triglyceride lipase or cholinesterase activity. Resorufin displays excitation/emission maxima of 570/580 nm, respectively.{50356}
Brand:CaymanSKU:19592 -Available on backorder
Resorufin butyrate is a fluorogenic substrate for triglyceride lipases.{31903} It is also a substrate for cholinesterase.{31902} Upon enzymatic cleavage by triglyceride lipases or cholinesterase, resorufin is released and can be used to quantify triglyceride lipase or cholinesterase activity. Resorufin displays excitation/emission maxima of 570/580 nm, respectively.{50356}
Brand:CaymanSKU:19592 -Available on backorder
Resorufin butyrate is a fluorogenic substrate for triglyceride lipases.{31903} It is also a substrate for cholinesterase.{31902} Upon enzymatic cleavage by triglyceride lipases or cholinesterase, resorufin is released and can be used to quantify triglyceride lipase or cholinesterase activity. Resorufin displays excitation/emission maxima of 570/580 nm, respectively.{50356}
Brand:CaymanSKU:19592 -Available on backorder
Resorufin butyrate is a fluorogenic substrate for triglyceride lipases.{31903} It is also a substrate for cholinesterase.{31902} Upon enzymatic cleavage by triglyceride lipases or cholinesterase, resorufin is released and can be used to quantify triglyceride lipase or cholinesterase activity. Resorufin displays excitation/emission maxima of 570/580 nm, respectively.{50356}
Brand:CaymanSKU:19592 -Available on backorder
Resorufin β-D-galactopyranoside is a fluorogenic substrate for β-galactosidase.{50356} Upon enzymatic cleavage by β-galactosidase, the fluorescent moiety resorufin is released and its fluorescence can be used to quantify β-galactosidase activity. Resorufin displays excitation/emission maxima of 570/580 nm, respectively.
Brand:CaymanSKU:28015 - 10 mgAvailable on backorder
Resorufin β-D-galactopyranoside is a fluorogenic substrate for β-galactosidase.{50356} Upon enzymatic cleavage by β-galactosidase, the fluorescent moiety resorufin is released and its fluorescence can be used to quantify β-galactosidase activity. Resorufin displays excitation/emission maxima of 570/580 nm, respectively.
Brand:CaymanSKU:28015 - 25 mgAvailable on backorder
Resorufin β-D-galactopyranoside is a fluorogenic substrate for β-galactosidase.{50356} Upon enzymatic cleavage by β-galactosidase, the fluorescent moiety resorufin is released and its fluorescence can be used to quantify β-galactosidase activity. Resorufin displays excitation/emission maxima of 570/580 nm, respectively.
Brand:CaymanSKU:28015 - 5 mgAvailable on backorder
Resorufin β-D-galactopyranoside is a fluorogenic substrate for β-galactosidase.{50356} Upon enzymatic cleavage by β-galactosidase, the fluorescent moiety resorufin is released and its fluorescence can be used to quantify β-galactosidase activity. Resorufin displays excitation/emission maxima of 570/580 nm, respectively.
Brand:CaymanSKU:28015 - 50 mgAvailable on backorder
Resveratrol-3-O-D-glycoside (piceide) is a stilbene glycoside and a natural precursor to the polyphenol resveratrol (Item Nos. 70675 | 10004235). It has anti-inflammatory and anti-oxidative properties.{34021,34018,34023,34024} In vitro, it dose-dependently (2.5-20 µg/ml) decreased IL-17 production in activated human peripheral blood mononuclear cells stimulated with anti-CD3/anti-CD28 monoclonal antibodies.{34021} In a doxorubicin-induced anti-oxidative stress mouse model, it was more effective than resveratrol at increasing total superoxide dismutase, catalase, and glutathione peroxidase activity in plasma.{34024} It improved learning and memory in a rat model of vascular dementia and showed promising results in cancer cells in vitro.{34022,34019,34020}
Brand:CaymanSKU:- Resveratrol-3-O-D-glycoside (piceide) is a stilbene glycoside and a natural precursor to the polyphenol resveratrol (Item Nos. 70675 | 10004235). It has anti-inflammatory and anti-oxidative properties.{34021,34018,34023,34024} In vitro, it dose-dependently (2.5-20 µg/ml) decreased IL-17 production in activated human peripheral blood mononuclear cells stimulated with anti-CD3/anti-CD28 monoclonal antibodies.{34021} In a doxorubicin-induced anti-oxidative stress mouse model, it was more effective than resveratrol at increasing total superoxide dismutase, catalase, and glutathione peroxidase activity in plasma.{34024} It improved learning and memory in a rat model of vascular dementia and showed promising results in cancer cells in vitro.{34022,34019,34020}
Brand:CaymanSKU:- Resveratrol-3-O-D-glycoside (piceide) is a stilbene glycoside and a natural precursor to the polyphenol resveratrol (Item Nos. 70675 | 10004235). It has anti-inflammatory and anti-oxidative properties.{34021,34018,34023,34024} In vitro, it dose-dependently (2.5-20 µg/ml) decreased IL-17 production in activated human peripheral blood mononuclear cells stimulated with anti-CD3/anti-CD28 monoclonal antibodies.{34021} In a doxorubicin-induced anti-oxidative stress mouse model, it was more effective than resveratrol at increasing total superoxide dismutase, catalase, and glutathione peroxidase activity in plasma.{34024} It improved learning and memory in a rat model of vascular dementia and showed promising results in cancer cells in vitro.{34022,34019,34020}
Brand:CaymanSKU:- Resveratrol-3-O-D-glycoside (piceide) is a stilbene glycoside and a natural precursor to the polyphenol resveratrol (Item Nos. 70675 | 10004235). It has anti-inflammatory and anti-oxidative properties.{34021,34018,34023,34024} In vitro, it dose-dependently (2.5-20 µg/ml) decreased IL-17 production in activated human peripheral blood mononuclear cells stimulated with anti-CD3/anti-CD28 monoclonal antibodies.{34021} In a doxorubicin-induced anti-oxidative stress mouse model, it was more effective than resveratrol at increasing total superoxide dismutase, catalase, and glutathione peroxidase activity in plasma.{34024} It improved learning and memory in a rat model of vascular dementia and showed promising results in cancer cells in vitro.{34022,34019,34020}
Brand:CaymanSKU:-
Resveratrol-3-O-sulfate is a metabolite of resveratrol (Item Nos. 70675 | 10004235).{37575} In U-937 cells stimulated with LPS, resveratrol-3-O-sulfate (1 µM) decreases the expression of IL-1α, IL-1β, and IL-6 by 61.2, 76.6, and 42.2%, respectively, and decreases the release of TNF-α and IL-6 to similar levels as resveratrol. It has antioxidant activity in a Trolox assay, dose-dependently decreases growth of Caco-2 colorectal adenocarcinoma cells when used at concentrations ranging from 10 to 100 µM, and induces apoptosis at concentrations of 25 and 50 µM.{37576} Resveratrol-3-O-sulfate also displaces rosiglitazone (Item No. 71740) from the outer mitochondrial protein mitoNEET (IC50 = 3.36 µM for the human protein), indicating that it binds to the thiazolidine-2,4-dione (TZD) binding pocket.{37577}
Brand:CaymanSKU:- Resveratrol-3-O-sulfate is a metabolite of resveratrol (Item Nos. 70675 | 10004235).{37575} In U-937 cells stimulated with LPS, resveratrol-3-O-sulfate (1 µM) decreases the expression of IL-1α, IL-1β, and IL-6 by 61.2, 76.6, and 42.2%, respectively, and decreases the release of TNF-α and IL-6 to similar levels as resveratrol. It has antioxidant activity in a Trolox assay, dose-dependently decreases growth of Caco-2 colorectal adenocarcinoma cells when used at concentrations ranging from 10 to 100 µM, and induces apoptosis at concentrations of 25 and 50 µM.{37576} Resveratrol-3-O-sulfate also displaces rosiglitazone (Item No. 71740) from the outer mitochondrial protein mitoNEET (IC50 = 3.36 µM for the human protein), indicating that it binds to the thiazolidine-2,4-dione (TZD) binding pocket.{37577}
Brand:CaymanSKU:-
RET kinase inhibitor 1 is an inhibitor of rearranged during transfection (RET) kinase (IC50 = 0.4 nM).{45511} It is selective for RET kinase over VEGF receptor 2 (VEGFR2/KDR; IC50 = 109 nM). RET kinase inhibitor 1 reduces the number of abdominal contractions induced by colorectal distension in acetic acid-sensitized rats when administered at a dose of 10 mg/kg twice per day.
Brand:CaymanSKU:24023 - 1 mgAvailable on backorder
RET kinase inhibitor 1 is an inhibitor of rearranged during transfection (RET) kinase (IC50 = 0.4 nM).{45511} It is selective for RET kinase over VEGF receptor 2 (VEGFR2/KDR; IC50 = 109 nM). RET kinase inhibitor 1 reduces the number of abdominal contractions induced by colorectal distension in acetic acid-sensitized rats when administered at a dose of 10 mg/kg twice per day.
Brand:CaymanSKU:24023 - 10 mgAvailable on backorder
RET kinase inhibitor 1 is an inhibitor of rearranged during transfection (RET) kinase (IC50 = 0.4 nM).{45511} It is selective for RET kinase over VEGF receptor 2 (VEGFR2/KDR; IC50 = 109 nM). RET kinase inhibitor 1 reduces the number of abdominal contractions induced by colorectal distension in acetic acid-sensitized rats when administered at a dose of 10 mg/kg twice per day.
Brand:CaymanSKU:24023 - 25 mgAvailable on backorder