Cayman
Showing 3301–3450 of 45550 results
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12:0 N-Biotinyl fatty acid is a biotinylated form of lauric acid (Item No. 10006626). It is an intermediate in the synthesis of N-biotinylated phenylarsonous acids.{47095}
Brand:CaymanSKU:25714 - 25 mgAvailable on backorder
12:0 N-Biotinyl fatty acid is a biotinylated form of lauric acid (Item No. 10006626). It is an intermediate in the synthesis of N-biotinylated phenylarsonous acids.{47095}
Brand:CaymanSKU:25714 - 5 mgAvailable on backorder
12(R)-HEPE is a monohydroxy fatty acid synthesized from EPA by the eggs of the sea urchin, S. purpuratus.{584} The biological activity of 12(R)-HEPE has not been extensively documented, but may be similar to that of 12(R)-HETE (Catalog No. 34560).{560,1406}
Brand:CaymanSKU:32545 - 100 µgAvailable on backorder
12(R)-HEPE is a monohydroxy fatty acid synthesized from EPA by the eggs of the sea urchin, S. purpuratus.{584} The biological activity of 12(R)-HEPE has not been extensively documented, but may be similar to that of 12(R)-HETE (Catalog No. 34560).{560,1406}
Brand:CaymanSKU:32545 - 25 µgAvailable on backorder
12(R)-HEPE is a monohydroxy fatty acid synthesized from EPA by the eggs of the sea urchin, S. purpuratus.{584} The biological activity of 12(R)-HEPE has not been extensively documented, but may be similar to that of 12(R)-HETE (Catalog No. 34560).{560,1406}
Brand:CaymanSKU:32545 - 50 µgAvailable on backorder
Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid (Item No. 90010).{584} In mammals, 12(R)-HETE can be produced by 12(R)-LOs and also by CYP450 oxidation.{559,562} The activity of 12(R)-HETE in mammals is predominantly proinflammatory.{559} 12(R)-HETE exhibits dose-dependent leukocyte chemotaxis at concentrations as low as 100 nM, and lowers intraocular pressure in rabbits.
Brand:CaymanSKU:34560 - 100 µgAvailable on backorder
Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid (Item No. 90010).{584} In mammals, 12(R)-HETE can be produced by 12(R)-LOs and also by CYP450 oxidation.{559,562} The activity of 12(R)-HETE in mammals is predominantly proinflammatory.{559} 12(R)-HETE exhibits dose-dependent leukocyte chemotaxis at concentrations as low as 100 nM, and lowers intraocular pressure in rabbits.
Brand:CaymanSKU:34560 - 25 µgAvailable on backorder
Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid (Item No. 90010).{584} In mammals, 12(R)-HETE can be produced by 12(R)-LOs and also by CYP450 oxidation.{559,562} The activity of 12(R)-HETE in mammals is predominantly proinflammatory.{559} 12(R)-HETE exhibits dose-dependent leukocyte chemotaxis at concentrations as low as 100 nM, and lowers intraocular pressure in rabbits.
Brand:CaymanSKU:34560 - 50 µgAvailable on backorder
12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway.{6402} The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids.
Brand:CaymanSKU:32550 - 100 µgAvailable on backorder
12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway.{6402} The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids.
Brand:CaymanSKU:32550 - 25 µgAvailable on backorder
12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway.{6402} The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids.
Brand:CaymanSKU:32550 - 50 µgAvailable on backorder
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.{498} It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.{591,880}
Brand:CaymanSKU:34570 - 100 µgAvailable on backorder
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.{498} It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.{591,880}
Brand:CaymanSKU:34570 - 25 µgAvailable on backorder
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.{498} It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.{591,880}
Brand:CaymanSKU:34570 - 50 µgAvailable on backorder
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.{498} It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.{591,880} 12(S)-HETE MaxSpec® standard is a quantitative grade standard of 12(S)-HETE (Item No. 34570) that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 12(S)-HETE MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Brand:CaymanSKU:10007248 - 10 µgAvailable on backorder
12(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. It is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS). 12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.{498} It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.{591,880}
Brand:CaymanSKU:334570 - 100 µgAvailable on backorder
12(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. It is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS). 12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.{498} It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.{591,880}
Brand:CaymanSKU:334570 - 25 µgAvailable on backorder
12(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. It is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS). 12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.{498} It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.{591,880}
Brand:CaymanSKU:334570 - 50 µgAvailable on backorder
12(S)-HETrE is produced by 12-lipoxygenase oxidation of dihomo-γ-linolenic acid (DGLA).{31110} 12(S)-HETrE is reported to inhibit agonist-mediated platelet activation (IC50 = 40 µM), α granule secretion, integrin αIIbβ3 activation, Rap1 activation, and thrombin-induced clot retraction in vitro.{31110}
Brand:CaymanSKU:-Available on backorder
12(S)-HETrE is produced by 12-lipoxygenase oxidation of dihomo-γ-linolenic acid (DGLA).{31110} 12(S)-HETrE is reported to inhibit agonist-mediated platelet activation (IC50 = 40 µM), α granule secretion, integrin αIIbβ3 activation, Rap1 activation, and thrombin-induced clot retraction in vitro.{31110}
Brand:CaymanSKU:-Available on backorder
12(S)-HETrE is produced by 12-lipoxygenase oxidation of dihomo-γ-linolenic acid (DGLA).{31110} 12(S)-HETrE is reported to inhibit agonist-mediated platelet activation (IC50 = 40 µM), α granule secretion, integrin αIIbβ3 activation, Rap1 activation, and thrombin-induced clot retraction in vitro.{31110}
Brand:CaymanSKU:-Available on backorder
12(S)-HETrE is produced by 12-lipoxygenase oxidation of dihomo-γ-linolenic acid (DGLA).{31110} 12(S)-HETrE is reported to inhibit agonist-mediated platelet activation (IC50 = 40 µM), α granule secretion, integrin αIIbβ3 activation, Rap1 activation, and thrombin-induced clot retraction in vitro.{31110}
Brand:CaymanSKU:-Available on backorder
12(S)-HHTrE is a product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of human platelets.{567} It is biosynthesized by thromboxane (TXA2) synthase from prostaglandin H2 (PGH2) concurrently with TXA2. 12(S)-HHTrE is a natural lipid agonist of the leukotriene B2 receptor BLT2 in vivo that induces chemotaxis of mast cells and accelerates wound closure.{15587,26266} 12(S)-HHTrE is avidly oxidized to 12-oxoHTrE by porcine 15-hydroxy PGDH.{566}
Brand:CaymanSKU:34590 - 100 µgAvailable on backorder
12(S)-HHTrE is a product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of human platelets.{567} It is biosynthesized by thromboxane (TXA2) synthase from prostaglandin H2 (PGH2) concurrently with TXA2. 12(S)-HHTrE is a natural lipid agonist of the leukotriene B2 receptor BLT2 in vivo that induces chemotaxis of mast cells and accelerates wound closure.{15587,26266} 12(S)-HHTrE is avidly oxidized to 12-oxoHTrE by porcine 15-hydroxy PGDH.{566}
Brand:CaymanSKU:34590 - 25 µgAvailable on backorder
12(S)-HHTrE is a product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of human platelets.{567} It is biosynthesized by thromboxane (TXA2) synthase from prostaglandin H2 (PGH2) concurrently with TXA2. 12(S)-HHTrE is a natural lipid agonist of the leukotriene B2 receptor BLT2 in vivo that induces chemotaxis of mast cells and accelerates wound closure.{15587,26266} 12(S)-HHTrE is avidly oxidized to 12-oxoHTrE by porcine 15-hydroxy PGDH.{566}
Brand:CaymanSKU:34590 - 250 µgAvailable on backorder
12(S)-HHTrE is a product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of human platelets.{567} It is biosynthesized by thromboxane (TXA2) synthase from prostaglandin H2 (PGH2) concurrently with TXA2. 12(S)-HHTrE is a natural lipid agonist of the leukotriene B2 receptor BLT2 in vivo that induces chemotaxis of mast cells and accelerates wound closure.{15587,26266} 12(S)-HHTrE is avidly oxidized to 12-oxoHTrE by porcine 15-hydroxy PGDH.{566}
Brand:CaymanSKU:34590 - 50 µgAvailable on backorder
12(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 12-lipoxygenase on eicosapentaenoic acid. Although the biological activities of 12(S)-HpEPE have not been well characterized, it is expected to behave similarly to 12(S)-HpETE (Catalog No. 44570).
Brand:CaymanSKU:42550 - 100 µgAvailable on backorder
12(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 12-lipoxygenase on eicosapentaenoic acid. Although the biological activities of 12(S)-HpEPE have not been well characterized, it is expected to behave similarly to 12(S)-HpETE (Catalog No. 44570).
Brand:CaymanSKU:42550 - 25 µgAvailable on backorder
12(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 12-lipoxygenase on eicosapentaenoic acid. Although the biological activities of 12(S)-HpEPE have not been well characterized, it is expected to behave similarly to 12(S)-HpETE (Catalog No. 44570).
Brand:CaymanSKU:42550 - 50 µgAvailable on backorder
12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid.{452,3959} It activates human blood leukocyte 5-LO, resulting in the synthesis of 5(S)-HETE, leukotriene B4 (LTB4), and 5(S),12(S)-DiHETE.{452} Rat lung metabolizes 12(S)-HpETE to 8,11,12- and 10,11,12-trihydroxyeicostrienoic acids.{194} 12(S)-HpETE is the mediator of many biological functions, including induction of c-fos and c-jun, activation of AP-1, and endothelium-dependent vasoconstriction.{6182,4194} It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons{624} and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex.{2366,624}
Brand:CaymanSKU:44570 - 100 µgAvailable on backorder
12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid.{452,3959} It activates human blood leukocyte 5-LO, resulting in the synthesis of 5(S)-HETE, leukotriene B4 (LTB4), and 5(S),12(S)-DiHETE.{452} Rat lung metabolizes 12(S)-HpETE to 8,11,12- and 10,11,12-trihydroxyeicostrienoic acids.{194} 12(S)-HpETE is the mediator of many biological functions, including induction of c-fos and c-jun, activation of AP-1, and endothelium-dependent vasoconstriction.{6182,4194} It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons{624} and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex.{2366,624}
Brand:CaymanSKU:44570 - 25 µgAvailable on backorder
12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid.{452,3959} It activates human blood leukocyte 5-LO, resulting in the synthesis of 5(S)-HETE, leukotriene B4 (LTB4), and 5(S),12(S)-DiHETE.{452} Rat lung metabolizes 12(S)-HpETE to 8,11,12- and 10,11,12-trihydroxyeicostrienoic acids.{194} 12(S)-HpETE is the mediator of many biological functions, including induction of c-fos and c-jun, activation of AP-1, and endothelium-dependent vasoconstriction.{6182,4194} It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons{624} and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex.{2366,624}
Brand:CaymanSKU:44570 - 250 µgAvailable on backorder
12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid.{452,3959} It activates human blood leukocyte 5-LO, resulting in the synthesis of 5(S)-HETE, leukotriene B4 (LTB4), and 5(S),12(S)-DiHETE.{452} Rat lung metabolizes 12(S)-HpETE to 8,11,12- and 10,11,12-trihydroxyeicostrienoic acids.{194} 12(S)-HpETE is the mediator of many biological functions, including induction of c-fos and c-jun, activation of AP-1, and endothelium-dependent vasoconstriction.{6182,4194} It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons{624} and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex.{2366,624}
Brand:CaymanSKU:44570 - 50 µgAvailable on backorder
12(S)-hydroxy-16-Heptadecynoic acid is a mechanism-based inhibitor of cytochrome P450 ω-hydroxylase.{1051} It inhibits prostaglandin ω-hydroxylase with a Ki value of 1.8 µM.{1051}
Brand:CaymanSKU:31570 - 1 mgAvailable on backorder
12(S)-hydroxy-16-Heptadecynoic acid is a mechanism-based inhibitor of cytochrome P450 ω-hydroxylase.{1051} It inhibits prostaglandin ω-hydroxylase with a Ki value of 1.8 µM.{1051}
Brand:CaymanSKU:31570 - 10 mgAvailable on backorder
12(S)-hydroxy-16-Heptadecynoic acid is a mechanism-based inhibitor of cytochrome P450 ω-hydroxylase.{1051} It inhibits prostaglandin ω-hydroxylase with a Ki value of 1.8 µM.{1051}
Brand:CaymanSKU:31570 - 5 mgAvailable on backorder
12(Z),15(Z)-Heneicosadienoic acid is an ω-6 very long-chain polyunsaturated fatty acid. It is a positional isomer of heneicosadienoic acid (Item No. 22593) that is rare in living organisms.{39308}
Brand:CaymanSKU:22594 -Out of stock
12(Z),15(Z)-Heneicosadienoic acid is an ω-6 very long-chain polyunsaturated fatty acid. It is a positional isomer of heneicosadienoic acid (Item No. 22593) that is rare in living organisms.{39308}
Brand:CaymanSKU:22594 -Out of stock
12(Z),15(Z)-Heneicosadienoic acid is an ω-6 very long-chain polyunsaturated fatty acid. It is a positional isomer of heneicosadienoic acid (Item No. 22593) that is rare in living organisms.{39308}
Brand:CaymanSKU:22594 -Out of stock
1233B is a fungal metabolite and an open-ring derivative of L-659,699 (hymeglusin; Item No. 11899) that lacks HMG-CoA synthase inhibitory activity.{49098,21712}
Brand:CaymanSKU:27712 - 1 mgAvailable on backorder
1233B is a fungal metabolite and an open-ring derivative of L-659,699 (hymeglusin; Item No. 11899) that lacks HMG-CoA synthase inhibitory activity.{49098,21712}
Brand:CaymanSKU:27712 - 500 µgAvailable on backorder
13-acetyl-9-Dihydrobaccatin III is a taxane originally isolated from T. canadensis.{54042} It inhibits proliferation of P388 leukemia cells with an IC50 value of 20 μg/ml.
Brand:CaymanSKU:29701 - 1 mgAvailable on backorder
13-acetyl-9-Dihydrobaccatin III is a taxane originally isolated from T. canadensis.{54042} It inhibits proliferation of P388 leukemia cells with an IC50 value of 20 μg/ml.
Brand:CaymanSKU:29701 - 10 mgAvailable on backorder
13-acetyl-9-Dihydrobaccatin III is a taxane originally isolated from T. canadensis.{54042} It inhibits proliferation of P388 leukemia cells with an IC50 value of 20 μg/ml.
Brand:CaymanSKU:29701 - 5 mgAvailable on backorder
13-cis Retinoic acid-d5 is intended for use as an internal standard for the quantification of 13-cis retinoic acid by GC- or LC-MS. 13-cis Retinoic acid is a naturally occurring retinoid that inhibits retinol oxidation and dehydrogenation of 17β-hydroxy steroids.{40199}
Brand:CaymanSKU:21855 -Out of stock
13-Docosenamide is the amide of docosenoic acid. It was first identified in the cerebrospinal fluid of sleep-deprived cats. It has also been detected in the cerebrospinal fluid of rats and humans.{1317} 13-Docosenamide causes reduced mobility and slightly lessened awareness in rats, whereas 9-octadecenamide induces physiological sleep.
Brand:CaymanSKU:90377 - 1 gAvailable on backorder
13-Docosenamide is the amide of docosenoic acid. It was first identified in the cerebrospinal fluid of sleep-deprived cats. It has also been detected in the cerebrospinal fluid of rats and humans.{1317} 13-Docosenamide causes reduced mobility and slightly lessened awareness in rats, whereas 9-octadecenamide induces physiological sleep.
Brand:CaymanSKU:90377 - 5 gAvailable on backorder
13-epi-12-oxo Phytodienoic acid (13-epi-12-oxo PDA) is a lipoxygenase metabolite of α-linolenic acid in the leaves of green plants such as corn. ω-3 and ω-6 polyunsaturated fatty acids in plants are substrates for plant lipoxygenases.{857} 12-oxo PDA is one of the best studied end metabolites of this enzymatic pathway.{1562} While the initial enzymatic product and major isomer of 12-oxo PDA contains side chains in the cis position, both being β to the ring, the upper side chain attached at C-13, can and frequently does, isomerize when 12-oxo PDA is extracted, isolated, or stored. 13-epi-12-oxo PDA is the product of this isomerization.
Brand:CaymanSKU:10195 - 1 mgAvailable on backorder
13-epi-12-oxo Phytodienoic acid (13-epi-12-oxo PDA) is a lipoxygenase metabolite of α-linolenic acid in the leaves of green plants such as corn. ω-3 and ω-6 polyunsaturated fatty acids in plants are substrates for plant lipoxygenases.{857} 12-oxo PDA is one of the best studied end metabolites of this enzymatic pathway.{1562} While the initial enzymatic product and major isomer of 12-oxo PDA contains side chains in the cis position, both being β to the ring, the upper side chain attached at C-13, can and frequently does, isomerize when 12-oxo PDA is extracted, isolated, or stored. 13-epi-12-oxo PDA is the product of this isomerization.
Brand:CaymanSKU:10195 - 100 µgAvailable on backorder
13-epi-12-oxo Phytodienoic acid (13-epi-12-oxo PDA) is a lipoxygenase metabolite of α-linolenic acid in the leaves of green plants such as corn. ω-3 and ω-6 polyunsaturated fatty acids in plants are substrates for plant lipoxygenases.{857} 12-oxo PDA is one of the best studied end metabolites of this enzymatic pathway.{1562} While the initial enzymatic product and major isomer of 12-oxo PDA contains side chains in the cis position, both being β to the ring, the upper side chain attached at C-13, can and frequently does, isomerize when 12-oxo PDA is extracted, isolated, or stored. 13-epi-12-oxo PDA is the product of this isomerization.
Brand:CaymanSKU:10195 - 500 µgAvailable on backorder
13-methyl Myristic acid is a methylated fatty acid that has been found in dairy ewe rumen liquor, bovine milk, goat milk fat, the edible flesh of rainbow trout (O. mykiss), and Flavobacterium.{39687,39688,39689,39690,39691} 13-methyl Myristic acid is also found in arable soil, and its levels decrease in response to contamination with the heavy metals cadmium, copper, nickel, and lead.{39692} [Matreya, LLC. Catalog No. 1605]
Brand:CaymanSKU:24811 - 10 mgAvailable on backorder
13-methyl Myristic acid is a methylated fatty acid that has been found in dairy ewe rumen liquor, bovine milk, goat milk fat, the edible flesh of rainbow trout (O. mykiss), and Flavobacterium.{39687,39688,39689,39690,39691} 13-methyl Myristic acid is also found in arable soil, and its levels decrease in response to contamination with the heavy metals cadmium, copper, nickel, and lead.{39692} [Matreya, LLC. Catalog No. 1605]
Brand:CaymanSKU:24811 - 25 mgAvailable on backorder
13-methyl Myristic acid is a methylated fatty acid that has been found in dairy ewe rumen liquor, bovine milk, goat milk fat, the edible flesh of rainbow trout (O. mykiss), and Flavobacterium.{39687,39688,39689,39690,39691} 13-methyl Myristic acid is also found in arable soil, and its levels decrease in response to contamination with the heavy metals cadmium, copper, nickel, and lead.{39692} [Matreya, LLC. Catalog No. 1605]
Brand:CaymanSKU:24811 - 5 mgAvailable on backorder
13-methyl Myristic acid methyl ester is a methylated bacterial fatty acid methyl ester.{39693,39694} It has been used as a marker of bacteria in sewage sludges and of bacterial contaminants in pharmaceutical manufacturing by GC-MS.{39695,39696} [Matreya, LLC. Catalog No. 1600]
Brand:CaymanSKU:24812 - 10 mgAvailable on backorder
13-methyl Myristic acid methyl ester is a methylated bacterial fatty acid methyl ester.{39693,39694} It has been used as a marker of bacteria in sewage sludges and of bacterial contaminants in pharmaceutical manufacturing by GC-MS.{39695,39696} [Matreya, LLC. Catalog No. 1600]
Brand:CaymanSKU:24812 - 25 mgAvailable on backorder
13-methyl Pentadecanoic acid methyl ester is a methylated fatty acid methyl ester that has been found in the bioactive fraction of A. malabarica extract, C. variabilis microalgae, and baboon liver.{39697,40927,39698} [Matreya, LLC. Catalog No. 1613]
Brand:CaymanSKU:24819 - 10 mgAvailable on backorder
13-methyl Pentadecanoic acid methyl ester is a methylated fatty acid methyl ester that has been found in the bioactive fraction of A. malabarica extract, C. variabilis microalgae, and baboon liver.{39697,40927,39698} [Matreya, LLC. Catalog No. 1613]
Brand:CaymanSKU:24819 - 25 mgAvailable on backorder
13-methyl Pentadecanoic acid methyl ester is a methylated fatty acid methyl ester that has been found in the bioactive fraction of A. malabarica extract, C. variabilis microalgae, and baboon liver.{39697,40927,39698} [Matreya, LLC. Catalog No. 1613]
Brand:CaymanSKU:24819 - 5 mgAvailable on backorder
13-Methylberberine (13-MB) (chloride) is a 13-methyl-substituted derivative of berberine (Item No. 10006427). Berberine is a widely distributed berberidaceaen alkaloid found in plant tissues that has antibacterial, anti-inflammatory, antitumor, anti-obesity, and hypercholesterolemic activity.{32930,12390} 13-MB has improved antibacterial activity against S. aureus (MIC = 125 µg/ml) and improved antitumor activity with a mean GI50 value of 11.7 µM, as compared to berberine.{37022,37023,37024} 13-MB also induces down-regulation of adipocyte differentiation transcription factors, reduces de novo lipid synthesis, and accumulates in murine 3T3-L1 adipocytes at higher levels than berberine, suggesting improved anti-obesity activity.{32930}
Brand:CaymanSKU:21154 -Out of stock
13-Methylberberine (13-MB) (chloride) is a 13-methyl-substituted derivative of berberine (Item No. 10006427). Berberine is a widely distributed berberidaceaen alkaloid found in plant tissues that has antibacterial, anti-inflammatory, antitumor, anti-obesity, and hypercholesterolemic activity.{32930,12390} 13-MB has improved antibacterial activity against S. aureus (MIC = 125 µg/ml) and improved antitumor activity with a mean GI50 value of 11.7 µM, as compared to berberine.{37022,37023,37024} 13-MB also induces down-regulation of adipocyte differentiation transcription factors, reduces de novo lipid synthesis, and accumulates in murine 3T3-L1 adipocytes at higher levels than berberine, suggesting improved anti-obesity activity.{32930}
Brand:CaymanSKU:21154 -Out of stock
13-Methylberberine (13-MB) (chloride) is a 13-methyl-substituted derivative of berberine (Item No. 10006427). Berberine is a widely distributed berberidaceaen alkaloid found in plant tissues that has antibacterial, anti-inflammatory, antitumor, anti-obesity, and hypercholesterolemic activity.{32930,12390} 13-MB has improved antibacterial activity against S. aureus (MIC = 125 µg/ml) and improved antitumor activity with a mean GI50 value of 11.7 µM, as compared to berberine.{37022,37023,37024} 13-MB also induces down-regulation of adipocyte differentiation transcription factors, reduces de novo lipid synthesis, and accumulates in murine 3T3-L1 adipocytes at higher levels than berberine, suggesting improved anti-obesity activity.{32930}
Brand:CaymanSKU:21154 -Out of stock
13-oxoODE is produced from 13-HODE by a NAD+-dependent dehydrogenase present in rat colonic mucosa.{184} 13-OxoODE stimulates cell proliferation when instilled intrarectally in rats.{2210} 13-OxoODE has also been detected in preparations of rabbit reticulocyte plasma and mitochondrial membranes, mostly esterified to phospholipids. Production of 13-oxoODE is putatively linked to the maturation of reticulocytes to erythrocytes through the activity of 15-LO.{2261,2262}
Brand:CaymanSKU:38620 - 100 µgAvailable on backorder
13-oxoODE is produced from 13-HODE by a NAD+-dependent dehydrogenase present in rat colonic mucosa.{184} 13-OxoODE stimulates cell proliferation when instilled intrarectally in rats.{2210} 13-OxoODE has also been detected in preparations of rabbit reticulocyte plasma and mitochondrial membranes, mostly esterified to phospholipids. Production of 13-oxoODE is putatively linked to the maturation of reticulocytes to erythrocytes through the activity of 15-LO.{2261,2262}
Brand:CaymanSKU:38620 - 25 µgAvailable on backorder
13-oxoODE is produced from 13-HODE by a NAD+-dependent dehydrogenase present in rat colonic mucosa.{184} 13-OxoODE stimulates cell proliferation when instilled intrarectally in rats.{2210} 13-OxoODE has also been detected in preparations of rabbit reticulocyte plasma and mitochondrial membranes, mostly esterified to phospholipids. Production of 13-oxoODE is putatively linked to the maturation of reticulocytes to erythrocytes through the activity of 15-LO.{2261,2262}
Brand:CaymanSKU:38620 - 50 µgAvailable on backorder
13,14-dehydro-15-cyclohexyl Carbaprostacyclin is a chemically stable analog of PGI2. It inhibits the ADP-induced aggregation of human platelets with an ED50 of about 40 nM in PRP and 77 nM in washed platelets, which is comparable to the potency of carbaprostacyclin.{1272,1283}
Brand:CaymanSKU:-Available on backorder
13,14-dehydro-15-cyclohexyl Carbaprostacyclin is a chemically stable analog of PGI2. It inhibits the ADP-induced aggregation of human platelets with an ED50 of about 40 nM in PRP and 77 nM in washed platelets, which is comparable to the potency of carbaprostacyclin.{1272,1283}
Brand:CaymanSKU:-Available on backorder
13,14-dehydro-15-cyclohexyl Carbaprostacyclin is a chemically stable analog of PGI2. It inhibits the ADP-induced aggregation of human platelets with an ED50 of about 40 nM in PRP and 77 nM in washed platelets, which is comparable to the potency of carbaprostacyclin.{1272,1283}
Brand:CaymanSKU:-Available on backorder
13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound.{4168,182} It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively.{1607} 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 (Item No. 13010) which has an IC50 value of 40 nM.{960} Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hybrid cells with a Kact value of 668 nM.{1926}
Brand:CaymanSKU:- 13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound.{4168,182} It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively.{1607} 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 (Item No. 13010) which has an IC50 value of 40 nM.{960} Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hybrid cells with a Kact value of 668 nM.{1926}
Brand:CaymanSKU:- 13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound.{4168,182} It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively.{1607} 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 (Item No. 13010) which has an IC50 value of 40 nM.{960} Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hybrid cells with a Kact value of 668 nM.{1926}
Brand:CaymanSKU:- 13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound.{4168,182} It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively.{1607} 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 (Item No. 13010) which has an IC50 value of 40 nM.{960} Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hybrid cells with a Kact value of 668 nM.{1926}
Brand:CaymanSKU:-
13,14-dihydro PGF1α is a potential metabolite of PGF1α.{2346} Its biological activity has not been reported. The corresponding compound in the E1 series (13,14-dihydro PGE1) retains biological activity similar to PGE1.{4168}
Brand:CaymanSKU:- 13,14-dihydro PGF1α is a potential metabolite of PGF1α.{2346} Its biological activity has not been reported. The corresponding compound in the E1 series (13,14-dihydro PGE1) retains biological activity similar to PGE1.{4168}
Brand:CaymanSKU:- 13,14-dihydro PGF1α is a potential metabolite of PGF1α.{2346} Its biological activity has not been reported. The corresponding compound in the E1 series (13,14-dihydro PGE1) retains biological activity similar to PGE1.{4168}
Brand:CaymanSKU:-
13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2α. The ED50 value for 13,14-dihydro PGF2α as a luteolytic agent in hamsters is 1.5 µg/100 g.{1795}
Brand:CaymanSKU:-Out of stock
13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2α. The ED50 value for 13,14-dihydro PGF2α as a luteolytic agent in hamsters is 1.5 µg/100 g.{1795}
Brand:CaymanSKU:-Out of stock
13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2α. The ED50 value for 13,14-dihydro PGF2α as a luteolytic agent in hamsters is 1.5 µg/100 g.{1795}
Brand:CaymanSKU:-Out of stock
PGE2 is metabolized rapidly to 13,14-dihydro-15-keto PGE2, which is present in the plasma of humans and other mammals. 13,14-dihydro-15-keto PGA2 results from the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2, a process which is accelerated by the presence of albumin.{581,366} Further decomposition of 13,14-dihydro-15-keto PGA2 by the intentional addition of base produces bicyclo PGE2, a stable marker of PGE2 biosynthesis.{366}
Brand:CaymanSKU:10260 - 1 mgAvailable on backorder
PGE2 is metabolized rapidly to 13,14-dihydro-15-keto PGE2, which is present in the plasma of humans and other mammals. 13,14-dihydro-15-keto PGA2 results from the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2, a process which is accelerated by the presence of albumin.{581,366} Further decomposition of 13,14-dihydro-15-keto PGA2 by the intentional addition of base produces bicyclo PGE2, a stable marker of PGE2 biosynthesis.{366}
Brand:CaymanSKU:10260 - 10 mgAvailable on backorder
PGE2 is metabolized rapidly to 13,14-dihydro-15-keto PGE2, which is present in the plasma of humans and other mammals. 13,14-dihydro-15-keto PGA2 results from the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2, a process which is accelerated by the presence of albumin.{581,366} Further decomposition of 13,14-dihydro-15-keto PGA2 by the intentional addition of base produces bicyclo PGE2, a stable marker of PGE2 biosynthesis.{366}
Brand:CaymanSKU:10260 - 5 mgAvailable on backorder
Prostaglandin E2 (PGE2; Item Nos. 14010 | 10007211) is metabolized rapidly to 13,14-dihydro-15-keto PGE2 (Item Nos. 14650 | 10007214), which is present in the plasma of humans and other mammals. 13,14-dihydro-15-keto PGA2 results from the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2, a process which is accelerated by the presence of albumin.{581,366} Further decomposition of 13,14-dihydro-15-keto PGA2 by the intentional addition of base produces bicyclo PGE2 (Item No. 14530), a stable marker of PGE2 biosynthesis.{366} 13,14-dihydro-15-keto PGA2 MaxSpec® standard is a quantitative grade standard of 13,14-dihydro-15-keto PGA2 (Item No. 10260) that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 13,14-dihydro-15-keto PGA2 MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batchspecific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Brand:CaymanSKU:10007200 - 100 µgAvailable on backorder