Cayman
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N-acetyl Sulfamethoxazole is a metabolite of sulfamethoxazole, an antibiotic with antiviral activity, that can be detected in urine.{27032,28148}
Brand:CaymanSKU:-Out of stock
N-acetyl Sulfamethoxazole is a metabolite of sulfamethoxazole, an antibiotic with antiviral activity, that can be detected in urine.{27032,28148}
Brand:CaymanSKU:-Out of stock
N-acetyl Sulfamethoxazole is a metabolite of sulfamethoxazole, an antibiotic with antiviral activity, that can be detected in urine.{27032,28148}
Brand:CaymanSKU:-Out of stock
N-acetyl Sulfamethoxazole is a metabolite of sulfamethoxazole, an antibiotic with antiviral activity, that can be detected in urine.{27032,28148}
Brand:CaymanSKU:-Out of stock
N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; Item No. 14427) that binds the melatonin MT2 receptor (Ki = 41 nM).{30340} It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina.{30338,30339,26017} N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.{30337}
Brand:CaymanSKU:-Available on backorder
N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; Item No. 14427) that binds the melatonin MT2 receptor (Ki = 41 nM).{30340} It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina.{30338,30339,26017} N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.{30337}
Brand:CaymanSKU:-Available on backorder
N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; Item No. 14427) that binds the melatonin MT2 receptor (Ki = 41 nM).{30340} It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina.{30338,30339,26017} N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.{30337}
Brand:CaymanSKU:-Available on backorder
N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; Item No. 14427) that binds the melatonin MT2 receptor (Ki = 41 nM).{30340} It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina.{30338,30339,26017} N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.{30337}
Brand:CaymanSKU:-Available on backorder
N-acetyl-2-carboxy Benzenesulfonamide is a structural analog of aspirin that acts as a non-selective inhibitor of cyclooxygenase (COX) with a COX-2 selectivity index of 0.23.{13010} In vitro studies showed that N-acetyl-2-carboxy Benzenesulfonamide is a more potent inhibitor of COX-1/COX-2 with IC50 values of 0.06 µM and 0.25 µM, respectively, than aspirin with IC50 values of 0.35 µM and 2.4 µM, respectively.
Brand:CaymanSKU:10008284 - 1 mgAvailable on backorder
N-acetyl-2-carboxy Benzenesulfonamide is a structural analog of aspirin that acts as a non-selective inhibitor of cyclooxygenase (COX) with a COX-2 selectivity index of 0.23.{13010} In vitro studies showed that N-acetyl-2-carboxy Benzenesulfonamide is a more potent inhibitor of COX-1/COX-2 with IC50 values of 0.06 µM and 0.25 µM, respectively, than aspirin with IC50 values of 0.35 µM and 2.4 µM, respectively.
Brand:CaymanSKU:10008284 - 10 mgAvailable on backorder
N-acetyl-2-carboxy Benzenesulfonamide is a structural analog of aspirin that acts as a non-selective inhibitor of cyclooxygenase (COX) with a COX-2 selectivity index of 0.23.{13010} In vitro studies showed that N-acetyl-2-carboxy Benzenesulfonamide is a more potent inhibitor of COX-1/COX-2 with IC50 values of 0.06 µM and 0.25 µM, respectively, than aspirin with IC50 values of 0.35 µM and 2.4 µM, respectively.
Brand:CaymanSKU:10008284 - 5 mgAvailable on backorder
N-acetyl-2-carboxy Benzenesulfonamide is a structural analog of aspirin that acts as a non-selective inhibitor of cyclooxygenase (COX) with a COX-2 selectivity index of 0.23.{13010} In vitro studies showed that N-acetyl-2-carboxy Benzenesulfonamide is a more potent inhibitor of COX-1/COX-2 with IC50 values of 0.06 µM and 0.25 µM, respectively, than aspirin with IC50 values of 0.35 µM and 2.4 µM, respectively.
Brand:CaymanSKU:10008284 - 50 mgAvailable on backorder
N-acetyl-2,3-dehydro-2-Deoxyneuraminic acid (DANA) is an inhibitor of human neuraminidases (sialidases) NEU1-4 (IC50s = 143, 43, 61, and 74 μM, respectively).{38566} In vivo, DANA (30 μl of a 5 mM solution) reduces latency to first seizure and increases seizure duration in a rat model of potassium-induced seizures.{38567}
Brand:CaymanSKU:19939 -Available on backorder
N-acetyl-2,3-dehydro-2-Deoxyneuraminic acid (DANA) is an inhibitor of human neuraminidases (sialidases) NEU1-4 (IC50s = 143, 43, 61, and 74 μM, respectively).{38566} In vivo, DANA (30 μl of a 5 mM solution) reduces latency to first seizure and increases seizure duration in a rat model of potassium-induced seizures.{38567}
Brand:CaymanSKU:19939 -Available on backorder
N-acetyl-2,3-dehydro-2-Deoxyneuraminic acid (DANA) is an inhibitor of human neuraminidases (sialidases) NEU1-4 (IC50s = 143, 43, 61, and 74 μM, respectively).{38566} In vivo, DANA (30 μl of a 5 mM solution) reduces latency to first seizure and increases seizure duration in a rat model of potassium-induced seizures.{38567}
Brand:CaymanSKU:19939 -Available on backorder
N-acetyl-3,4-Methylenedioxymethcathinone (N-acetyl-3,4-MDMC) is an acetylated analog of methylone (Item No. 10986), the MDMA-type designer drug that has been detected in products marketed as bath salts, plant food, and tablets.{19508,19756} The biological actions of N-acetyl-3,4-MDMC are unknown. This product is intended for forensic and research purposes.
Brand:CaymanSKU:9001492 - 10 mgAvailable on backorder
N-acetyl-3,4-Methylenedioxymethcathinone (N-acetyl-3,4-MDMC) is an acetylated analog of methylone (Item No. 10986), the MDMA-type designer drug that has been detected in products marketed as bath salts, plant food, and tablets.{19508,19756} The biological actions of N-acetyl-3,4-MDMC are unknown. This product is intended for forensic and research purposes.
Brand:CaymanSKU:9001492 - 5 mgAvailable on backorder
N-acetyl-3,4-Methylenedioxymethcathinone (N-acetyl-3,4-MDMC) is an acetylated analog of methylone (Item No. 10986), the MDMA-type designer drug that has been detected in products marketed as bath salts, plant food, and tablets.{19508,19756} The biological actions of N-acetyl-3,4-MDMC are unknown. This product is intended for forensic and research purposes.
Brand:CaymanSKU:9001492 - 50 mgAvailable on backorder
N-Acetyl-4-benzoquinone imine (NAPQI) is a cytochrome P450 3A4 and 2E1 metabolite of acetaminophen that can be toxic to the liver when acetaminophen is consumed in large doses.{7361} At therapeutic doses of acetaminophen, NAPQI is inactivated by conjugation with glutathione. However, following toxic doses of acetaminophen, available liver reserves of glutathione are quickly depleted due to clearance of excess NAPQI, which enables hepatic proteins to become covalently modified by reactive metabolites and eventually results in hepatocyte necrosis.{7361}
Brand:CaymanSKU:- N-Acetyl-4-benzoquinone imine (NAPQI) is a cytochrome P450 3A4 and 2E1 metabolite of acetaminophen that can be toxic to the liver when acetaminophen is consumed in large doses.{7361} At therapeutic doses of acetaminophen, NAPQI is inactivated by conjugation with glutathione. However, following toxic doses of acetaminophen, available liver reserves of glutathione are quickly depleted due to clearance of excess NAPQI, which enables hepatic proteins to become covalently modified by reactive metabolites and eventually results in hepatocyte necrosis.{7361}
Brand:CaymanSKU:- N-Acetyl-4-benzoquinone imine (NAPQI) is a cytochrome P450 3A4 and 2E1 metabolite of acetaminophen that can be toxic to the liver when acetaminophen is consumed in large doses.{7361} At therapeutic doses of acetaminophen, NAPQI is inactivated by conjugation with glutathione. However, following toxic doses of acetaminophen, available liver reserves of glutathione are quickly depleted due to clearance of excess NAPQI, which enables hepatic proteins to become covalently modified by reactive metabolites and eventually results in hepatocyte necrosis.{7361}
Brand:CaymanSKU:-
N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid (5-ASA; Item No. 70265) and its prodrug form, sulfasalazine (Item No. 15025).{42753,8455} It is formed in the liver, intestinal lumen, and colonic epithelial cells via N-acetyltransferases.{42754} It reduces IFN-γ binding to colonic epithelial cells by 24% when used at a concentration of 10 mM.{42756} N-acetyl-5-Aminosalicylic acid (100 µM) scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay and inhibits base hydroxylation in DNA stimulated by hydroxy radicals.{42753,42755} Unlike sulfasalazine, N-acetyl-5-aminosalicylic acid does not inhibit 15-hydroxy prostaglandin dehydrogenase (PGDH).{8455} Urinary levels of N-acetyl-5-aminosalicylic acid have been used as a marker of 5-ASA adherence in patients with inflammatory bowel disease.{42757}
Brand:CaymanSKU:27618 - 100 mgAvailable on backorder
N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid (5-ASA; Item No. 70265) and its prodrug form, sulfasalazine (Item No. 15025).{42753,8455} It is formed in the liver, intestinal lumen, and colonic epithelial cells via N-acetyltransferases.{42754} It reduces IFN-γ binding to colonic epithelial cells by 24% when used at a concentration of 10 mM.{42756} N-acetyl-5-Aminosalicylic acid (100 µM) scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay and inhibits base hydroxylation in DNA stimulated by hydroxy radicals.{42753,42755} Unlike sulfasalazine, N-acetyl-5-aminosalicylic acid does not inhibit 15-hydroxy prostaglandin dehydrogenase (PGDH).{8455} Urinary levels of N-acetyl-5-aminosalicylic acid have been used as a marker of 5-ASA adherence in patients with inflammatory bowel disease.{42757}
Brand:CaymanSKU:27618 - 25 mgAvailable on backorder
N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid (5-ASA; Item No. 70265) and its prodrug form, sulfasalazine (Item No. 15025).{42753,8455} It is formed in the liver, intestinal lumen, and colonic epithelial cells via N-acetyltransferases.{42754} It reduces IFN-γ binding to colonic epithelial cells by 24% when used at a concentration of 10 mM.{42756} N-acetyl-5-Aminosalicylic acid (100 µM) scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay and inhibits base hydroxylation in DNA stimulated by hydroxy radicals.{42753,42755} Unlike sulfasalazine, N-acetyl-5-aminosalicylic acid does not inhibit 15-hydroxy prostaglandin dehydrogenase (PGDH).{8455} Urinary levels of N-acetyl-5-aminosalicylic acid have been used as a marker of 5-ASA adherence in patients with inflammatory bowel disease.{42757}
Brand:CaymanSKU:27618 - 250 mgAvailable on backorder
N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid (5-ASA; Item No. 70265) and its prodrug form, sulfasalazine (Item No. 15025).{42753,8455} It is formed in the liver, intestinal lumen, and colonic epithelial cells via N-acetyltransferases.{42754} It reduces IFN-γ binding to colonic epithelial cells by 24% when used at a concentration of 10 mM.{42756} N-acetyl-5-Aminosalicylic acid (100 µM) scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay and inhibits base hydroxylation in DNA stimulated by hydroxy radicals.{42753,42755} Unlike sulfasalazine, N-acetyl-5-aminosalicylic acid does not inhibit 15-hydroxy prostaglandin dehydrogenase (PGDH).{8455} Urinary levels of N-acetyl-5-aminosalicylic acid have been used as a marker of 5-ASA adherence in patients with inflammatory bowel disease.{42757}
Brand:CaymanSKU:27618 - 50 mgAvailable on backorder
N-acetyl-D-Galactosamine (GalNAc) is an amino sugar derivative of galactose and a component of O-GalNAc glycans.{61099,61100} It is transferred from UDP-GalNAc to the hydroxy group of protein serine or threonine residues by polypeptide GalNAc transferase, forming the Tn antigen, during the first step of mucin-type O-glycosylation.{61101,61100} GalNAc has been used as a targeting moiety for liver-targeted delivery of oligonucleotides.{61099}
Brand:CaymanSKU:31728 - 1 gAvailable on backorder
N-acetyl-D-Galactosamine (GalNAc) is an amino sugar derivative of galactose and a component of O-GalNAc glycans.{61099,61100} It is transferred from UDP-GalNAc to the hydroxy group of protein serine or threonine residues by polypeptide GalNAc transferase, forming the Tn antigen, during the first step of mucin-type O-glycosylation.{61101,61100} GalNAc has been used as a targeting moiety for liver-targeted delivery of oligonucleotides.{61099}
Brand:CaymanSKU:31728 - 5 gAvailable on backorder
N-acetyl-D-Galactosamine (GalNAc) is an amino sugar derivative of galactose and a component of O-GalNAc glycans.{61099,61100} It is transferred from UDP-GalNAc to the hydroxy group of protein serine or threonine residues by polypeptide GalNAc transferase, forming the Tn antigen, during the first step of mucin-type O-glycosylation.{61101,61100} GalNAc has been used as a targeting moiety for liver-targeted delivery of oligonucleotides.{61099}
Brand:CaymanSKU:31728 - 500 mgAvailable on backorder
N-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc. Levels of O-GlcNAcylation proteins from Alzheimer’s disease brain extracts are decreased as compared to that in controls, suggesting that release of GlcNAc may contribute to pathogenesis.{16842} In E. coli, GlcNAc induces the expression of multidrug exporter genes, indicating that this sugar can alter gene expression.{16842} GlcNAc is also the monomeric unit of chitin, which is found in fungi and many invertebrates, including crustaceans, insects, and nematodes. For this reason, chemicals that inhibit the incorporation of GlcNAc into chitin are cytotoxic to these organisms.
Brand:CaymanSKU:- N-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc. Levels of O-GlcNAcylation proteins from Alzheimer’s disease brain extracts are decreased as compared to that in controls, suggesting that release of GlcNAc may contribute to pathogenesis.{16842} In E. coli, GlcNAc induces the expression of multidrug exporter genes, indicating that this sugar can alter gene expression.{16842} GlcNAc is also the monomeric unit of chitin, which is found in fungi and many invertebrates, including crustaceans, insects, and nematodes. For this reason, chemicals that inhibit the incorporation of GlcNAc into chitin are cytotoxic to these organisms.
Brand:CaymanSKU:- N-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc. Levels of O-GlcNAcylation proteins from Alzheimer’s disease brain extracts are decreased as compared to that in controls, suggesting that release of GlcNAc may contribute to pathogenesis.{16842} In E. coli, GlcNAc induces the expression of multidrug exporter genes, indicating that this sugar can alter gene expression.{16842} GlcNAc is also the monomeric unit of chitin, which is found in fungi and many invertebrates, including crustaceans, insects, and nematodes. For this reason, chemicals that inhibit the incorporation of GlcNAc into chitin are cytotoxic to these organisms.
Brand:CaymanSKU:- N-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc. Levels of O-GlcNAcylation proteins from Alzheimer’s disease brain extracts are decreased as compared to that in controls, suggesting that release of GlcNAc may contribute to pathogenesis.{16842} In E. coli, GlcNAc induces the expression of multidrug exporter genes, indicating that this sugar can alter gene expression.{16842} GlcNAc is also the monomeric unit of chitin, which is found in fungi and many invertebrates, including crustaceans, insects, and nematodes. For this reason, chemicals that inhibit the incorporation of GlcNAc into chitin are cytotoxic to these organisms.
Brand:CaymanSKU:-
N-acetyl-D-Lactosamine is a disaccharide consisting of galactose and N-acetylglucose. It occurs naturally as a structural element in a variety of glycoconjugates.{33091} N-acetyl-D-Lactosamine is used to characterize lectins. {33090}
Brand:CaymanSKU:21043 -Out of stock
N-acetyl-D-Lactosamine is a disaccharide consisting of galactose and N-acetylglucose. It occurs naturally as a structural element in a variety of glycoconjugates.{33091} N-acetyl-D-Lactosamine is used to characterize lectins. {33090}
Brand:CaymanSKU:21043 -Out of stock
N-acetyl-D-Lactosamine is a disaccharide consisting of galactose and N-acetylglucose. It occurs naturally as a structural element in a variety of glycoconjugates.{33091} N-acetyl-D-Lactosamine is used to characterize lectins. {33090}
Brand:CaymanSKU:21043 -Out of stock
N-acetyl-D-Lactosamine is a disaccharide consisting of galactose and N-acetylglucose. It occurs naturally as a structural element in a variety of glycoconjugates.{33091} N-acetyl-D-Lactosamine is used to characterize lectins. {33090}
Brand:CaymanSKU:21043 -Out of stock
N-acetyl-D-Leucine is a derivative of D-leucine and a substrate for various enzymes in the amidohydrolase superfamily.{48994} It has been used to characterize the function of amidohydrolase enzymes from B. bronchiseptica, S. coelicolor, and G. oxydans.
Brand:CaymanSKU:30489 - 1 gAvailable on backorder
N-acetyl-D-Leucine is a derivative of D-leucine and a substrate for various enzymes in the amidohydrolase superfamily.{48994} It has been used to characterize the function of amidohydrolase enzymes from B. bronchiseptica, S. coelicolor, and G. oxydans.
Brand:CaymanSKU:30489 - 500 mgAvailable on backorder
Sialic acids, commonly present as terminal carbohydrates on glycoconjugates, are essential for a variety of cellular functions including cell adhesion and signal recognition as well as the formation and progression of tumors.{16261} Disruption of sialic acid biosynthesis can result in severe glomerular proteinuria or neuromuscular disorders such as hereditary inclusion body myopathy (HIBM).{16263} N-Acetyl-D-mannosamine (ManNAc) is the precursor of all physiological sialic acids. Intraperitoneal injection of ManNAc twice daily at 1,000 mg/kg in C57BL/6 mice for 13 days leads to increased sialylation in kidney, liver, blood cells, brain, spinal cord, muscle, heart, lung, and spleen.{16262} ManNAc reverses hyposialylation and improves glomerular integrity in GneM712T/M712T mice whose key enzyme for sialic acid production has been deleted and may prove therapeutic in the treatment of HIBM.{16263}
Brand:CaymanSKU:10011060 - 1 gAvailable on backorder
Sialic acids, commonly present as terminal carbohydrates on glycoconjugates, are essential for a variety of cellular functions including cell adhesion and signal recognition as well as the formation and progression of tumors.{16261} Disruption of sialic acid biosynthesis can result in severe glomerular proteinuria or neuromuscular disorders such as hereditary inclusion body myopathy (HIBM).{16263} N-Acetyl-D-mannosamine (ManNAc) is the precursor of all physiological sialic acids. Intraperitoneal injection of ManNAc twice daily at 1,000 mg/kg in C57BL/6 mice for 13 days leads to increased sialylation in kidney, liver, blood cells, brain, spinal cord, muscle, heart, lung, and spleen.{16262} ManNAc reverses hyposialylation and improves glomerular integrity in GneM712T/M712T mice whose key enzyme for sialic acid production has been deleted and may prove therapeutic in the treatment of HIBM.{16263}
Brand:CaymanSKU:10011060 - 100 mgAvailable on backorder
Sialic acids, commonly present as terminal carbohydrates on glycoconjugates, are essential for a variety of cellular functions including cell adhesion and signal recognition as well as the formation and progression of tumors.{16261} Disruption of sialic acid biosynthesis can result in severe glomerular proteinuria or neuromuscular disorders such as hereditary inclusion body myopathy (HIBM).{16263} N-Acetyl-D-mannosamine (ManNAc) is the precursor of all physiological sialic acids. Intraperitoneal injection of ManNAc twice daily at 1,000 mg/kg in C57BL/6 mice for 13 days leads to increased sialylation in kidney, liver, blood cells, brain, spinal cord, muscle, heart, lung, and spleen.{16262} ManNAc reverses hyposialylation and improves glomerular integrity in GneM712T/M712T mice whose key enzyme for sialic acid production has been deleted and may prove therapeutic in the treatment of HIBM.{16263}
Brand:CaymanSKU:10011060 - 250 mgAvailable on backorder
Sialic acids, commonly present as terminal carbohydrates on glycoconjugates, are essential for a variety of cellular functions including cell adhesion and signal recognition as well as the formation and progression of tumors.{16261} Disruption of sialic acid biosynthesis can result in severe glomerular proteinuria or neuromuscular disorders such as hereditary inclusion body myopathy (HIBM).{16263} N-Acetyl-D-mannosamine (ManNAc) is the precursor of all physiological sialic acids. Intraperitoneal injection of ManNAc twice daily at 1,000 mg/kg in C57BL/6 mice for 13 days leads to increased sialylation in kidney, liver, blood cells, brain, spinal cord, muscle, heart, lung, and spleen.{16262} ManNAc reverses hyposialylation and improves glomerular integrity in GneM712T/M712T mice whose key enzyme for sialic acid production has been deleted and may prove therapeutic in the treatment of HIBM.{16263}
Brand:CaymanSKU:10011060 - 500 mgAvailable on backorder
N-Acetyl-DL-penicillamine is a chelating agent.{45968,45972,45969} It inhibits the binding of methyl mercury to isolated human erythrocytes by 50% and removes 50% of methyl mercury ions from methyl mercury-loaded blood cells when used at a concentration of 1 mM.{45968,45972} N-Acetyl-DL-penicillamine (3 mmol/kg per day, p.o.) reduces the biological half-life of mercury and decreases liver, kidney, brain, and blood mercury levels, as well as increases urinary excretion of mercury in a concentration-dependent manner, in mice when administered following injection of methyl mercuric chloride. It decreases mercuric chloride-induced mortality in mice when administered orally at a dose of 1.6 mmol/kg.{45969} N-Acetyl-DL-penicillamine is also an analog of SNAP (Item No. 82250) that does not generate nitric oxide and has been used as a negative control in experiments using SNAP.{45970,45971}
Brand:CaymanSKU:10010404 - 1 gAvailable on backorder
N-Acetyl-DL-penicillamine is a chelating agent.{45968,45972,45969} It inhibits the binding of methyl mercury to isolated human erythrocytes by 50% and removes 50% of methyl mercury ions from methyl mercury-loaded blood cells when used at a concentration of 1 mM.{45968,45972} N-Acetyl-DL-penicillamine (3 mmol/kg per day, p.o.) reduces the biological half-life of mercury and decreases liver, kidney, brain, and blood mercury levels, as well as increases urinary excretion of mercury in a concentration-dependent manner, in mice when administered following injection of methyl mercuric chloride. It decreases mercuric chloride-induced mortality in mice when administered orally at a dose of 1.6 mmol/kg.{45969} N-Acetyl-DL-penicillamine is also an analog of SNAP (Item No. 82250) that does not generate nitric oxide and has been used as a negative control in experiments using SNAP.{45970,45971}
Brand:CaymanSKU:10010404 - 250 mgAvailable on backorder
N-Acetyl-DL-penicillamine is a chelating agent.{45968,45972,45969} It inhibits the binding of methyl mercury to isolated human erythrocytes by 50% and removes 50% of methyl mercury ions from methyl mercury-loaded blood cells when used at a concentration of 1 mM.{45968,45972} N-Acetyl-DL-penicillamine (3 mmol/kg per day, p.o.) reduces the biological half-life of mercury and decreases liver, kidney, brain, and blood mercury levels, as well as increases urinary excretion of mercury in a concentration-dependent manner, in mice when administered following injection of methyl mercuric chloride. It decreases mercuric chloride-induced mortality in mice when administered orally at a dose of 1.6 mmol/kg.{45969} N-Acetyl-DL-penicillamine is also an analog of SNAP (Item No. 82250) that does not generate nitric oxide and has been used as a negative control in experiments using SNAP.{45970,45971}
Brand:CaymanSKU:10010404 - 5 gAvailable on backorder
N-Acetyl-DL-penicillamine is a chelating agent.{45968,45972,45969} It inhibits the binding of methyl mercury to isolated human erythrocytes by 50% and removes 50% of methyl mercury ions from methyl mercury-loaded blood cells when used at a concentration of 1 mM.{45968,45972} N-Acetyl-DL-penicillamine (3 mmol/kg per day, p.o.) reduces the biological half-life of mercury and decreases liver, kidney, brain, and blood mercury levels, as well as increases urinary excretion of mercury in a concentration-dependent manner, in mice when administered following injection of methyl mercuric chloride. It decreases mercuric chloride-induced mortality in mice when administered orally at a dose of 1.6 mmol/kg.{45969} N-Acetyl-DL-penicillamine is also an analog of SNAP (Item No. 82250) that does not generate nitric oxide and has been used as a negative control in experiments using SNAP.{45970,45971}
Brand:CaymanSKU:10010404 - 500 mgAvailable on backorder
N-acetyl-L-Carnosine is a dipeptide and acetylated form of L-carnosine (Item No. 29825) that has been found in heart and skeletal muscle and has antioxidant and anticataract activities.{30665,57282} It reduces iron- and ascorbate-induced malondialdehyde (MDA) accumulation in liposomes when used at concentrations of 10 and 20 mM.{30665} Topical administration of N-acetyl-L-carnosine (1% v/v) reduces cortical opacities in a canine model of age-related cataracts.{57282}
Brand:CaymanSKU:-Available on backorder
N-acetyl-L-Carnosine is a dipeptide and acetylated form of L-carnosine (Item No. 29825) that has been found in heart and skeletal muscle and has antioxidant and anticataract activities.{30665,57282} It reduces iron- and ascorbate-induced malondialdehyde (MDA) accumulation in liposomes when used at concentrations of 10 and 20 mM.{30665} Topical administration of N-acetyl-L-carnosine (1% v/v) reduces cortical opacities in a canine model of age-related cataracts.{57282}
Brand:CaymanSKU:-Available on backorder
N-acetyl-L-Carnosine is a dipeptide and acetylated form of L-carnosine (Item No. 29825) that has been found in heart and skeletal muscle and has antioxidant and anticataract activities.{30665,57282} It reduces iron- and ascorbate-induced malondialdehyde (MDA) accumulation in liposomes when used at concentrations of 10 and 20 mM.{30665} Topical administration of N-acetyl-L-carnosine (1% v/v) reduces cortical opacities in a canine model of age-related cataracts.{57282}
Brand:CaymanSKU:-Available on backorder
N-Acetyl-L-cysteine (NAC) is an antioxidant and precursor of glutathione that has multiple effects in cells and animals. As an antioxidant, NAC scavenges hydrogen peroxide, hydroxyl radical, and hypochlorous acid.{32379,32381} NAC may be deacetylated to cysteine, which can be combined with glutamate and glycine to produce reduced glutathione (Item No. 10007461), which serves to reduce hydroperoxides and detoxify xenobiotics.{32379,32381} The free sulfhydryl group of NAC can also hydrolyze disulfide bonds of mucins and other proteins, thus facilitating clearance of mucus.{32384} Through these actions, NAC inhibits DNA adduct formation, limits hepatotoxic effects of acetaminophen, and provides diverse cytoprotective effects in vivo.{32378,32379,32380,32381,32384,32385}
Brand:CaymanSKU:20261 -Available on backorder
N-Acetyl-L-cysteine (NAC) is an antioxidant and precursor of glutathione that has multiple effects in cells and animals. As an antioxidant, NAC scavenges hydrogen peroxide, hydroxyl radical, and hypochlorous acid.{32379,32381} NAC may be deacetylated to cysteine, which can be combined with glutamate and glycine to produce reduced glutathione (Item No. 10007461), which serves to reduce hydroperoxides and detoxify xenobiotics.{32379,32381} The free sulfhydryl group of NAC can also hydrolyze disulfide bonds of mucins and other proteins, thus facilitating clearance of mucus.{32384} Through these actions, NAC inhibits DNA adduct formation, limits hepatotoxic effects of acetaminophen, and provides diverse cytoprotective effects in vivo.{32378,32379,32380,32381,32384,32385}
Brand:CaymanSKU:20261 -Available on backorder
N-Acetyl-L-cysteine (NAC) is an antioxidant and precursor of glutathione that has multiple effects in cells and animals. As an antioxidant, NAC scavenges hydrogen peroxide, hydroxyl radical, and hypochlorous acid.{32379,32381} NAC may be deacetylated to cysteine, which can be combined with glutamate and glycine to produce reduced glutathione (Item No. 10007461), which serves to reduce hydroperoxides and detoxify xenobiotics.{32379,32381} The free sulfhydryl group of NAC can also hydrolyze disulfide bonds of mucins and other proteins, thus facilitating clearance of mucus.{32384} Through these actions, NAC inhibits DNA adduct formation, limits hepatotoxic effects of acetaminophen, and provides diverse cytoprotective effects in vivo.{32378,32379,32380,32381,32384,32385}
Brand:CaymanSKU:20261 -Available on backorder
N-Acetyl-L-cysteine (NAC) is an antioxidant and precursor of glutathione that has multiple effects in cells and animals. As an antioxidant, NAC scavenges hydrogen peroxide, hydroxyl radical, and hypochlorous acid.{32379,32381} NAC may be deacetylated to cysteine, which can be combined with glutamate and glycine to produce reduced glutathione (Item No. 10007461), which serves to reduce hydroperoxides and detoxify xenobiotics.{32379,32381} The free sulfhydryl group of NAC can also hydrolyze disulfide bonds of mucins and other proteins, thus facilitating clearance of mucus.{32384} Through these actions, NAC inhibits DNA adduct formation, limits hepatotoxic effects of acetaminophen, and provides diverse cytoprotective effects in vivo.{32378,32379,32380,32381,32384,32385}
Brand:CaymanSKU:20261 -Available on backorder
N-acetyl-L-Cysteine amide (NACA) is an antioxidant.{48071,48072} It is the amide form of N-acetyl-L-cysteine (NAC; Item No. 20261) and has increased cellular membrane and blood-brain barrier permeability compared to NAC. NACA (750 μM) inhibits glutamate-induced cytotoxicity, decreases in intracellular glutathione (GSH) levels, and increases in intracellular reactive oxygen species (ROS) levels in PC12 cells.{48073} It reduces cortical tissue damage and decreases the distance traveled to the platform in the Morris water maze in a rat model of traumatic brain injury.{48072} NACA (60 and 120 mg/kg) also inhibits ovalbumin-induced decreases in GSH, increases in nuclear NF-κB p65 and HIF-1α, and increases in IL-4, IL-5, and IL-13 levels in mouse lung tissue.{48074}
Brand:CaymanSKU:25866 - 10 mgAvailable on backorder
N-acetyl-L-Cysteine amide (NACA) is an antioxidant.{48071,48072} It is the amide form of N-acetyl-L-cysteine (NAC; Item No. 20261) and has increased cellular membrane and blood-brain barrier permeability compared to NAC. NACA (750 μM) inhibits glutamate-induced cytotoxicity, decreases in intracellular glutathione (GSH) levels, and increases in intracellular reactive oxygen species (ROS) levels in PC12 cells.{48073} It reduces cortical tissue damage and decreases the distance traveled to the platform in the Morris water maze in a rat model of traumatic brain injury.{48072} NACA (60 and 120 mg/kg) also inhibits ovalbumin-induced decreases in GSH, increases in nuclear NF-κB p65 and HIF-1α, and increases in IL-4, IL-5, and IL-13 levels in mouse lung tissue.{48074}
Brand:CaymanSKU:25866 - 25 mgAvailable on backorder
N-acetyl-L-Cysteine amide (NACA) is an antioxidant.{48071,48072} It is the amide form of N-acetyl-L-cysteine (NAC; Item No. 20261) and has increased cellular membrane and blood-brain barrier permeability compared to NAC. NACA (750 μM) inhibits glutamate-induced cytotoxicity, decreases in intracellular glutathione (GSH) levels, and increases in intracellular reactive oxygen species (ROS) levels in PC12 cells.{48073} It reduces cortical tissue damage and decreases the distance traveled to the platform in the Morris water maze in a rat model of traumatic brain injury.{48072} NACA (60 and 120 mg/kg) also inhibits ovalbumin-induced decreases in GSH, increases in nuclear NF-κB p65 and HIF-1α, and increases in IL-4, IL-5, and IL-13 levels in mouse lung tissue.{48074}
Brand:CaymanSKU:25866 - 5 mgAvailable on backorder
N-acetyl-L-Cysteine amide (NACA) is an antioxidant.{48071,48072} It is the amide form of N-acetyl-L-cysteine (NAC; Item No. 20261) and has increased cellular membrane and blood-brain barrier permeability compared to NAC. NACA (750 μM) inhibits glutamate-induced cytotoxicity, decreases in intracellular glutathione (GSH) levels, and increases in intracellular reactive oxygen species (ROS) levels in PC12 cells.{48073} It reduces cortical tissue damage and decreases the distance traveled to the platform in the Morris water maze in a rat model of traumatic brain injury.{48072} NACA (60 and 120 mg/kg) also inhibits ovalbumin-induced decreases in GSH, increases in nuclear NF-κB p65 and HIF-1α, and increases in IL-4, IL-5, and IL-13 levels in mouse lung tissue.{48074}
Brand:CaymanSKU:25866 - 50 mgAvailable on backorder
N-acetyl-L-Cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC; Item No. 20261). It has enhanced cell permeability in isolated perfused rat liver compared to NAC.{53848} N-acetyl-L-Cysteine ethyl ester (1 mM) prevents tert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells. It increases glutathione levels in rat liver, kidney, heart, testis, and brain when administered at a dose of 50 mg/kg twice per day for two weeks. N-acetyl-L-Cysteine ethyl ester reduces increases in plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels induced by paracetamol (acetaminophen; Item No. 10024) in rats.
Brand:CaymanSKU:30299 - 10 mgAvailable on backorder
N-acetyl-L-Cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC; Item No. 20261). It has enhanced cell permeability in isolated perfused rat liver compared to NAC.{53848} N-acetyl-L-Cysteine ethyl ester (1 mM) prevents tert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells. It increases glutathione levels in rat liver, kidney, heart, testis, and brain when administered at a dose of 50 mg/kg twice per day for two weeks. N-acetyl-L-Cysteine ethyl ester reduces increases in plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels induced by paracetamol (acetaminophen; Item No. 10024) in rats.
Brand:CaymanSKU:30299 - 100 mgAvailable on backorder
N-acetyl-L-Cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC; Item No. 20261). It has enhanced cell permeability in isolated perfused rat liver compared to NAC.{53848} N-acetyl-L-Cysteine ethyl ester (1 mM) prevents tert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells. It increases glutathione levels in rat liver, kidney, heart, testis, and brain when administered at a dose of 50 mg/kg twice per day for two weeks. N-acetyl-L-Cysteine ethyl ester reduces increases in plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels induced by paracetamol (acetaminophen; Item No. 10024) in rats.
Brand:CaymanSKU:30299 - 5 mgAvailable on backorder
N-acetyl-L-Cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC; Item No. 20261). It has enhanced cell permeability in isolated perfused rat liver compared to NAC.{53848} N-acetyl-L-Cysteine ethyl ester (1 mM) prevents tert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells. It increases glutathione levels in rat liver, kidney, heart, testis, and brain when administered at a dose of 50 mg/kg twice per day for two weeks. N-acetyl-L-Cysteine ethyl ester reduces increases in plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels induced by paracetamol (acetaminophen; Item No. 10024) in rats.
Brand:CaymanSKU:30299 - 50 mgAvailable on backorder
L-Deoxyalliin (Item No. 14014), also known as S-allyl-L-cysteine, is a water soluble organosulfur compound derived from garlic that has neuroprotective and antioxidative activities.{21895,21907} N-Acetyl-S-allyl-L-cysteine is a principal metabolite of L-deoxyalliin in humans, mice, rats, and dogs.{28672,28673,28671} It is readily detected in plasma and urine. The conversion of L-deoxyalliin to N-acetyl-S-allyl-L-cysteine appears to be mediated by a family of flavin-containing monooxygenases.{28673,28674}
Brand:CaymanSKU:-Available on backorder
L-Deoxyalliin (Item No. 14014), also known as S-allyl-L-cysteine, is a water soluble organosulfur compound derived from garlic that has neuroprotective and antioxidative activities.{21895,21907} N-Acetyl-S-allyl-L-cysteine is a principal metabolite of L-deoxyalliin in humans, mice, rats, and dogs.{28672,28673,28671} It is readily detected in plasma and urine. The conversion of L-deoxyalliin to N-acetyl-S-allyl-L-cysteine appears to be mediated by a family of flavin-containing monooxygenases.{28673,28674}
Brand:CaymanSKU:-Available on backorder
L-Deoxyalliin (Item No. 14014), also known as S-allyl-L-cysteine, is a water soluble organosulfur compound derived from garlic that has neuroprotective and antioxidative activities.{21895,21907} N-Acetyl-S-allyl-L-cysteine is a principal metabolite of L-deoxyalliin in humans, mice, rats, and dogs.{28672,28673,28671} It is readily detected in plasma and urine. The conversion of L-deoxyalliin to N-acetyl-S-allyl-L-cysteine appears to be mediated by a family of flavin-containing monooxygenases.{28673,28674}
Brand:CaymanSKU:-Available on backorder
N-acetyl-S-farnesyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase).{2306,2304} Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.
Brand:CaymanSKU:63270 - 1 mgAvailable on backorder
N-acetyl-S-farnesyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase).{2306,2304} Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.
Brand:CaymanSKU:63270 - 10 mgAvailable on backorder
N-acetyl-S-farnesyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase).{2306,2304} Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.
Brand:CaymanSKU:63270 - 25 mgAvailable on backorder
N-acetyl-S-farnesyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase).{2306,2304} Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.
Brand:CaymanSKU:63270 - 5 mgAvailable on backorder
N-acetyl-S-geranylgeranyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase).{2306,2304} Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.
Brand:CaymanSKU:63340 - 1 mgAvailable on backorder
N-acetyl-S-geranylgeranyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase).{2306,2304} Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.
Brand:CaymanSKU:63340 - 10 mgAvailable on backorder
N-acetyl-S-geranylgeranyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase).{2306,2304} Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.
Brand:CaymanSKU:63340 - 25 mgAvailable on backorder
N-acetyl-S-geranylgeranyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase).{2306,2304} Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.
Brand:CaymanSKU:63340 - 5 mgAvailable on backorder
N-Acetylmethamphetamine (Item No. 27889) is an analytical reference standard categorized as an amphetamine. N-Acetylmethamphetamine is a by-product formed in the synthesis of methamphetamine from pseudoephedrine.{35847} It can also be formed as an analytical artifact in the injector during GC-MS analysis. This product is intended for research and forensic applications.
Brand:CaymanSKU:27889 - 1 mgAvailable on backorder
N-Acetylmethamphetamine (Item No. 27889) is an analytical reference standard categorized as an amphetamine. N-Acetylmethamphetamine is a by-product formed in the synthesis of methamphetamine from pseudoephedrine.{35847} It can also be formed as an analytical artifact in the injector during GC-MS analysis. This product is intended for research and forensic applications.
Brand:CaymanSKU:27889 - 5 mgAvailable on backorder
N-Acetylmuramic acid (MurNAc) is a component of the glycan strands in bacterial peptidoglycan.{59328} It is linked to N-acetylglucosamine (GlcNAc) by β-1,4 linkages in an alternating pattern, as well as to the peptide side chains via its lactyl side chain, in native peptidoglycan.
Brand:CaymanSKU:31330 - 100 mgAvailable on backorder
N-Acetylmuramic acid (MurNAc) is a component of the glycan strands in bacterial peptidoglycan.{59328} It is linked to N-acetylglucosamine (GlcNAc) by β-1,4 linkages in an alternating pattern, as well as to the peptide side chains via its lactyl side chain, in native peptidoglycan.
Brand:CaymanSKU:31330 - 25 mgAvailable on backorder
N-Acetylmuramic acid (MurNAc) is a component of the glycan strands in bacterial peptidoglycan.{59328} It is linked to N-acetylglucosamine (GlcNAc) by β-1,4 linkages in an alternating pattern, as well as to the peptide side chains via its lactyl side chain, in native peptidoglycan.
Brand:CaymanSKU:31330 - 250 mgAvailable on backorder
N-Acetylmuramic acid (MurNAc) is a component of the glycan strands in bacterial peptidoglycan.{59328} It is linked to N-acetylglucosamine (GlcNAc) by β-1,4 linkages in an alternating pattern, as well as to the peptide side chains via its lactyl side chain, in native peptidoglycan.
Brand:CaymanSKU:31330 - 50 mgAvailable on backorder
Salic acids are nine-carbon carbohydrate α-keto acids that have many important biological functions, including cell-cell recognition and host-pathogen interactions.{26390,6370} N-Acetylneuraminic acid (NANA) is the most abundant sialic acid and is found in bacteria as well as in eukaryotic cells.{26390,26388} The pathways for NANA synthesis and metabolism in bacteria differ from those used in eukaryotic cells.{26388} This sialic acid is an essential component of human brain gangliosides and sialylated glycoproteins.{26389}
Brand:CaymanSKU:- Salic acids are nine-carbon carbohydrate α-keto acids that have many important biological functions, including cell-cell recognition and host-pathogen interactions.{26390,6370} N-Acetylneuraminic acid (NANA) is the most abundant sialic acid and is found in bacteria as well as in eukaryotic cells.{26390,26388} The pathways for NANA synthesis and metabolism in bacteria differ from those used in eukaryotic cells.{26388} This sialic acid is an essential component of human brain gangliosides and sialylated glycoproteins.{26389}
Brand:CaymanSKU:- Salic acids are nine-carbon carbohydrate α-keto acids that have many important biological functions, including cell-cell recognition and host-pathogen interactions.{26390,6370} N-Acetylneuraminic acid (NANA) is the most abundant sialic acid and is found in bacteria as well as in eukaryotic cells.{26390,26388} The pathways for NANA synthesis and metabolism in bacteria differ from those used in eukaryotic cells.{26388} This sialic acid is an essential component of human brain gangliosides and sialylated glycoproteins.{26389}
Brand:CaymanSKU:-