Cayman
Showing 28951–29100 of 45550 results
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Mer-NF5003F is a sesquiterpene originally isolated from Stachybotrys with diverse biological activities.{46742,46743,46744} It inhibits avian myeloblastosis virus (AMV) protease (IC50 = 7.8 µM).{46742} Mer-NF5003F inhibits sialyltransferase 6N (ST6N), ST3O, and ST3N (IC50s = 0.61, 6.7, and 10 µg/ml, respectively), as well as fucosyltransferase (IC50 = 11.3 µg/ml).{46743} It is active against herpes simplex virus 1 (HSV-1) in vitro (IC50 = 4.32 µg/ml).{46744} Mer-NF5003F is also active against the multidrug-resistant P. falciparum strain K1 (IC50 = 0.85 µg/ml).
Brand:CaymanSKU:29961 - 5 mgAvailable on backorder
Merimepodib is an inhibitor of inosine-5′-monophosphate dehydrogenase (IMPDH; Kis = 7 and 10 nM for IMPDH type I and type II, respectively) with antiviral and immunosuppressant activities.{53250} It reduces Ebola, Lassa, chikungunya, Junin, and Zika virus titers in vitro and inhibits Zika virus replication in Huh7 cells (EC50 = 0.6 µM).{53251} Merimepodib inhibits the proliferation of PHA-stimulated T cells and SPAS-stimulated B cells (IC50s = 104 and 132 nM, respectively), effects that can be reversed by guanosine (Item No. 27702) but not adenosine (Item No. 21232).{53252} In vivo, merimepodib (50 and 100 mg/kg) increases allograft survival in a murine skin transplantation model and prevents development of graft versus host disease (GVHD) in splenocyte allografted mice.{53253}
Brand:CaymanSKU:29351 - 1 mgAvailable on backorder
Merimepodib is an inhibitor of inosine-5′-monophosphate dehydrogenase (IMPDH; Kis = 7 and 10 nM for IMPDH type I and type II, respectively) with antiviral and immunosuppressant activities.{53250} It reduces Ebola, Lassa, chikungunya, Junin, and Zika virus titers in vitro and inhibits Zika virus replication in Huh7 cells (EC50 = 0.6 µM).{53251} Merimepodib inhibits the proliferation of PHA-stimulated T cells and SPAS-stimulated B cells (IC50s = 104 and 132 nM, respectively), effects that can be reversed by guanosine (Item No. 27702) but not adenosine (Item No. 21232).{53252} In vivo, merimepodib (50 and 100 mg/kg) increases allograft survival in a murine skin transplantation model and prevents development of graft versus host disease (GVHD) in splenocyte allografted mice.{53253}
Brand:CaymanSKU:29351 - 10 mgAvailable on backorder
Merimepodib is an inhibitor of inosine-5′-monophosphate dehydrogenase (IMPDH; Kis = 7 and 10 nM for IMPDH type I and type II, respectively) with antiviral and immunosuppressant activities.{53250} It reduces Ebola, Lassa, chikungunya, Junin, and Zika virus titers in vitro and inhibits Zika virus replication in Huh7 cells (EC50 = 0.6 µM).{53251} Merimepodib inhibits the proliferation of PHA-stimulated T cells and SPAS-stimulated B cells (IC50s = 104 and 132 nM, respectively), effects that can be reversed by guanosine (Item No. 27702) but not adenosine (Item No. 21232).{53252} In vivo, merimepodib (50 and 100 mg/kg) increases allograft survival in a murine skin transplantation model and prevents development of graft versus host disease (GVHD) in splenocyte allografted mice.{53253}
Brand:CaymanSKU:29351 - 25 mgAvailable on backorder
Merimepodib is an inhibitor of inosine-5′-monophosphate dehydrogenase (IMPDH; Kis = 7 and 10 nM for IMPDH type I and type II, respectively) with antiviral and immunosuppressant activities.{53250} It reduces Ebola, Lassa, chikungunya, Junin, and Zika virus titers in vitro and inhibits Zika virus replication in Huh7 cells (EC50 = 0.6 µM).{53251} Merimepodib inhibits the proliferation of PHA-stimulated T cells and SPAS-stimulated B cells (IC50s = 104 and 132 nM, respectively), effects that can be reversed by guanosine (Item No. 27702) but not adenosine (Item No. 21232).{53252} In vivo, merimepodib (50 and 100 mg/kg) increases allograft survival in a murine skin transplantation model and prevents development of graft versus host disease (GVHD) in splenocyte allografted mice.{53253}
Brand:CaymanSKU:29351 - 5 mgAvailable on backorder
Meropenem is a carbapenem antibiotic.{26435} It is active against clinical isolates of Gram-positive and Gram-negative bacteria in vitro, including S. pneumoniae, H. influenzae, N. gonorrhoeae, E. coli, P. aeruginosa, C. difficile, and methicillin-susceptible and -resistant S. aureus (MICs = ≤0.008-8 μg/ml). It is protective against S. aureus, S. pneumoniae, E. coli, S. marcescens, P. mirabilis, and P. aeruginosa infections in mice with 50% protective dose (PD50) values of 0.13, 0.01, 0.04, 0.07, 0.84, and 0.46 mg/kg, respectively.{53193} Formulations containing meropenem have been used in the treatment of a variety of bacterial infections.
Brand:CaymanSKU:- Meropenem is a carbapenem antibiotic.{26435} It is active against clinical isolates of Gram-positive and Gram-negative bacteria in vitro, including S. pneumoniae, H. influenzae, N. gonorrhoeae, E. coli, P. aeruginosa, C. difficile, and methicillin-susceptible and -resistant S. aureus (MICs = ≤0.008-8 μg/ml). It is protective against S. aureus, S. pneumoniae, E. coli, S. marcescens, P. mirabilis, and P. aeruginosa infections in mice with 50% protective dose (PD50) values of 0.13, 0.01, 0.04, 0.07, 0.84, and 0.46 mg/kg, respectively.{53193} Formulations containing meropenem have been used in the treatment of a variety of bacterial infections.
Brand:CaymanSKU:- Meropenem is a carbapenem antibiotic.{26435} It is active against clinical isolates of Gram-positive and Gram-negative bacteria in vitro, including S. pneumoniae, H. influenzae, N. gonorrhoeae, E. coli, P. aeruginosa, C. difficile, and methicillin-susceptible and -resistant S. aureus (MICs = ≤0.008-8 μg/ml). It is protective against S. aureus, S. pneumoniae, E. coli, S. marcescens, P. mirabilis, and P. aeruginosa infections in mice with 50% protective dose (PD50) values of 0.13, 0.01, 0.04, 0.07, 0.84, and 0.46 mg/kg, respectively.{53193} Formulations containing meropenem have been used in the treatment of a variety of bacterial infections.
Brand:CaymanSKU:- Meropenem is a carbapenem antibiotic.{26435} It is active against clinical isolates of Gram-positive and Gram-negative bacteria in vitro, including S. pneumoniae, H. influenzae, N. gonorrhoeae, E. coli, P. aeruginosa, C. difficile, and methicillin-susceptible and -resistant S. aureus (MICs = ≤0.008-8 μg/ml). It is protective against S. aureus, S. pneumoniae, E. coli, S. marcescens, P. mirabilis, and P. aeruginosa infections in mice with 50% protective dose (PD50) values of 0.13, 0.01, 0.04, 0.07, 0.84, and 0.46 mg/kg, respectively.{53193} Formulations containing meropenem have been used in the treatment of a variety of bacterial infections.
Brand:CaymanSKU:-
Meropenem-d6 is intended for use as an internal standard for the quantification of meropenem (Item No. 16068) by GC- or LC-MS. Meropenem is a carbapenem antibiotic.{26435} It is active against clinical isolates of Gram-positive and Gram-negative bacteria in vitro, including S. pneumoniae, H. influenzae, N. gonorrhoeae, E. coli, P. aeruginosa, C. difficile, and methicillin-susceptible and -resistant S. aureus (MICs = ≤0.008-8 μg/ml). It is protective against S. aureus, S. pneumoniae, E. coli, S. marcescens, P. mirabilis, and P. aeruginosa infections in mice with 50% protective dose (PD50) values of 0.13, 0.01, 0.04, 0.07, 0.84, and 0.46 mg/kg, respectively.{53193} Formulations containing meropenem have been used in the treatment of a variety of bacterial infections.
Brand:CaymanSKU:28616 - 1 mgAvailable on backorder
Mertansine is a thiol-containing derivative of maytansine that is cytotoxic to human epidermoid carcinoma KB and human breast cancer SK-BR-3 cells (IC50 = 1.10 nM for both).{35116} Formulations containing mertansine have been studied for the treatment of multiple myeloma and squamous cell carcinoma.{35114,35115}
Brand:CaymanSKU:22483 -Out of stock
Mertansine is a thiol-containing derivative of maytansine that is cytotoxic to human epidermoid carcinoma KB and human breast cancer SK-BR-3 cells (IC50 = 1.10 nM for both).{35116} Formulations containing mertansine have been studied for the treatment of multiple myeloma and squamous cell carcinoma.{35114,35115}
Brand:CaymanSKU:22483 -Out of stock
Mertansine is a thiol-containing derivative of maytansine that is cytotoxic to human epidermoid carcinoma KB and human breast cancer SK-BR-3 cells (IC50 = 1.10 nM for both).{35116} Formulations containing mertansine have been studied for the treatment of multiple myeloma and squamous cell carcinoma.{35114,35115}
Brand:CaymanSKU:22483 -Out of stock
Mescaline is a psychedelic phenethylamine that is found naturally in plants predominantly in the cactus family, including peyote (L. williamsii). It binds and activates serotonin receptors, with preference for 5-HT2A over 5-HT2C (EC50 = 4 and 24 μM, respectively).{21525} This product is intended for research and forensic purposes.
Brand:CaymanSKU:-
Mesna is a cofactor found in methanogenic archaea that is essential for the final step of methanogenesis and is also important for alkene metabolism.{33384} It functions as an antioxidant and cytoprotective agent and is widely used for protection from toxicity of chemotherapeutic agents.{33385} In the bladder, mesna conjugates to urotoxic metabolites such as acrolein through a Michael addition, converting the toxic compound into inactive metabolites that can be excreted in the urine.{33385}
Brand:CaymanSKU:21238 -Out of stock
Mesna is a cofactor found in methanogenic archaea that is essential for the final step of methanogenesis and is also important for alkene metabolism.{33384} It functions as an antioxidant and cytoprotective agent and is widely used for protection from toxicity of chemotherapeutic agents.{33385} In the bladder, mesna conjugates to urotoxic metabolites such as acrolein through a Michael addition, converting the toxic compound into inactive metabolites that can be excreted in the urine.{33385}
Brand:CaymanSKU:21238 -Out of stock
meso-2,3-Dimercaptosuccinic acid is a heavy metal chelator.{45474} It reverses sodium arsenite-induced inhibition of pyruvate dehydrogenase (PDH) in mouse kidney homogenates (EC50 = 0.25 mM). meso-2,3-Dimercaptosuccinic acid decreases cisplatin-induced increases in serum levels of platinum and blood urea nitrogen (BUN), as well as apoptosis in renal tubules of mice when administered at a dose of 100 µM/kg.{45475} meso-2,3-Dimercaptosuccinic acid (90 mg/kg) decreases elevations in the activity of catalase and glucose-6-phosphate dehydrogenase (G6PDH) in RBCs from lead-exposed rats, and decreases the levels of lead in the cerebellum, hippocampus, liver, kidney, and blood in rats when administered at a dose of 100 mg/kg.{45476,45477} It decreases immobility time in the forced swim test in lead-exposed male, but not female, mice when administered at a dose of 50 mg/kg.{45478} Formulations containing meso-2,3-dimercaptosuccinic acid have been used in the treatment of heavy metal poisoning.
Brand:CaymanSKU:28515 - 1 gAvailable on backorder
meso-2,3-Dimercaptosuccinic acid is a heavy metal chelator.{45474} It reverses sodium arsenite-induced inhibition of pyruvate dehydrogenase (PDH) in mouse kidney homogenates (EC50 = 0.25 mM). meso-2,3-Dimercaptosuccinic acid decreases cisplatin-induced increases in serum levels of platinum and blood urea nitrogen (BUN), as well as apoptosis in renal tubules of mice when administered at a dose of 100 µM/kg.{45475} meso-2,3-Dimercaptosuccinic acid (90 mg/kg) decreases elevations in the activity of catalase and glucose-6-phosphate dehydrogenase (G6PDH) in RBCs from lead-exposed rats, and decreases the levels of lead in the cerebellum, hippocampus, liver, kidney, and blood in rats when administered at a dose of 100 mg/kg.{45476,45477} It decreases immobility time in the forced swim test in lead-exposed male, but not female, mice when administered at a dose of 50 mg/kg.{45478} Formulations containing meso-2,3-dimercaptosuccinic acid have been used in the treatment of heavy metal poisoning.
Brand:CaymanSKU:28515 - 10 gAvailable on backorder
meso-2,3-Dimercaptosuccinic acid is a heavy metal chelator.{45474} It reverses sodium arsenite-induced inhibition of pyruvate dehydrogenase (PDH) in mouse kidney homogenates (EC50 = 0.25 mM). meso-2,3-Dimercaptosuccinic acid decreases cisplatin-induced increases in serum levels of platinum and blood urea nitrogen (BUN), as well as apoptosis in renal tubules of mice when administered at a dose of 100 µM/kg.{45475} meso-2,3-Dimercaptosuccinic acid (90 mg/kg) decreases elevations in the activity of catalase and glucose-6-phosphate dehydrogenase (G6PDH) in RBCs from lead-exposed rats, and decreases the levels of lead in the cerebellum, hippocampus, liver, kidney, and blood in rats when administered at a dose of 100 mg/kg.{45476,45477} It decreases immobility time in the forced swim test in lead-exposed male, but not female, mice when administered at a dose of 50 mg/kg.{45478} Formulations containing meso-2,3-dimercaptosuccinic acid have been used in the treatment of heavy metal poisoning.
Brand:CaymanSKU:28515 - 5 gAvailable on backorder
Mesoridazine is an active metabolite of the typical antipsychotic thioridazine (Item No. 14400).{56193,56195} It is formed via sulfoxidation of thioridazine by the cytochrome P450 (CYP) isoform CYP2D6 in human liver microsomes.{56194} It binds to histamine H1, dopamine D2, muscarinic acetylcholine, and α1- and α2-adrenergic receptors (Kds = 1.8, 19, 69, 2, and 1,600 nM, respectively).{56195} Mesoridazine (10, 30, and 45 mg/kg, i.p.) prevents mescaline-induced hyperactivity in mice.{56196}
Brand:CaymanSKU:31370 - 10 mgAvailable on backorder
Mesoridazine is an active metabolite of the typical antipsychotic thioridazine (Item No. 14400).{56193,56195} It is formed via sulfoxidation of thioridazine by the cytochrome P450 (CYP) isoform CYP2D6 in human liver microsomes.{56194} It binds to histamine H1, dopamine D2, muscarinic acetylcholine, and α1- and α2-adrenergic receptors (Kds = 1.8, 19, 69, 2, and 1,600 nM, respectively).{56195} Mesoridazine (10, 30, and 45 mg/kg, i.p.) prevents mescaline-induced hyperactivity in mice.{56196}
Brand:CaymanSKU:31370 - 100 mgAvailable on backorder
Mesoridazine is an active metabolite of the typical antipsychotic thioridazine (Item No. 14400).{56193,56195} It is formed via sulfoxidation of thioridazine by the cytochrome P450 (CYP) isoform CYP2D6 in human liver microsomes.{56194} It binds to histamine H1, dopamine D2, muscarinic acetylcholine, and α1- and α2-adrenergic receptors (Kds = 1.8, 19, 69, 2, and 1,600 nM, respectively).{56195} Mesoridazine (10, 30, and 45 mg/kg, i.p.) prevents mescaline-induced hyperactivity in mice.{56196}
Brand:CaymanSKU:31370 - 25 mgAvailable on backorder
Mesoridazine is an active metabolite of the typical antipsychotic thioridazine (Item No. 14400).{56193,56195} It is formed via sulfoxidation of thioridazine by the cytochrome P450 (CYP) isoform CYP2D6 in human liver microsomes.{56194} It binds to histamine H1, dopamine D2, muscarinic acetylcholine, and α1- and α2-adrenergic receptors (Kds = 1.8, 19, 69, 2, and 1,600 nM, respectively).{56195} Mesoridazine (10, 30, and 45 mg/kg, i.p.) prevents mescaline-induced hyperactivity in mice.{56196}
Brand:CaymanSKU:31370 - 50 mgAvailable on backorder
Mestranol is a semi-synthetic estrogen prodrug of ethynyl estradiol (Item No. 10006486), an estrogen receptor agonist.{41236} It is demethylated in the liver to ethynyl estradiol. Mestranol has estrogenic properties, inducing RNA synthesis in homogenized mouse uteri following a dose of 1.6 µg/animal, which is 16-fold higher than the dose of ethynyl estradiol needed to induce a similar response.{41237} Formulations containing mestranol were previously used as oral contraceptives.
Brand:CaymanSKU:23822 - 10 mgAvailable on backorder
Mestranol is a semi-synthetic estrogen prodrug of ethynyl estradiol (Item No. 10006486), an estrogen receptor agonist.{41236} It is demethylated in the liver to ethynyl estradiol. Mestranol has estrogenic properties, inducing RNA synthesis in homogenized mouse uteri following a dose of 1.6 µg/animal, which is 16-fold higher than the dose of ethynyl estradiol needed to induce a similar response.{41237} Formulations containing mestranol were previously used as oral contraceptives.
Brand:CaymanSKU:23822 - 100 mgAvailable on backorder
Mestranol is a semi-synthetic estrogen prodrug of ethynyl estradiol (Item No. 10006486), an estrogen receptor agonist.{41236} It is demethylated in the liver to ethynyl estradiol. Mestranol has estrogenic properties, inducing RNA synthesis in homogenized mouse uteri following a dose of 1.6 µg/animal, which is 16-fold higher than the dose of ethynyl estradiol needed to induce a similar response.{41237} Formulations containing mestranol were previously used as oral contraceptives.
Brand:CaymanSKU:23822 - 50 mgAvailable on backorder
meta-fluoro 4-ANBP (Item No. 25959) is an analytical reference standard that is structurally similar to known opioids. It is a potential impurity in the synthesis of N-benzyl meta-fluoro norfentanyl (Item No. 25541). This product is intended for research and forensic applications.
Brand:CaymanSKU:25959 - 1 mgAvailable on backorder
meta-fluoro 4-ANBP (Item No. 25959) is an analytical reference standard that is structurally similar to known opioids. It is a potential impurity in the synthesis of N-benzyl meta-fluoro norfentanyl (Item No. 25541). This product is intended for research and forensic applications.
Brand:CaymanSKU:25959 - 5 mgAvailable on backorder
meta-Fluoxetine is an isomer of fluoxetine (Item No. 14418) that is found as an impurity in fluoxetine preparations. meta-Fluoxetine is a weaker serotonin selective reuptake inhibitor (SSRI) than fluoxetine, in which the trifluoromethyl group is at the para position (Kis = 166 and 17 nM, respectively, in rat brain synaptosomes).{36026,36027}
Brand:CaymanSKU:22158 -Out of stock
meta-Fluoxetine is an isomer of fluoxetine (Item No. 14418) that is found as an impurity in fluoxetine preparations. meta-Fluoxetine is a weaker serotonin selective reuptake inhibitor (SSRI) than fluoxetine, in which the trifluoromethyl group is at the para position (Kis = 166 and 17 nM, respectively, in rat brain synaptosomes).{36026,36027}
Brand:CaymanSKU:22158 -Out of stock
meta-Fluoxetine is an isomer of fluoxetine (Item No. 14418) that is found as an impurity in fluoxetine preparations. meta-Fluoxetine is a weaker serotonin selective reuptake inhibitor (SSRI) than fluoxetine, in which the trifluoromethyl group is at the para position (Kis = 166 and 17 nM, respectively, in rat brain synaptosomes).{36026,36027}
Brand:CaymanSKU:22158 -Out of stock
Metaescaline (hydrochloride) (Item No. 19927) is an analytical reference standard that is structurally classified as a phenethylamine. It is a derivative of escaline (Item No. 14107) in which the single ethyl group is reoriented to the meta position.{31967} This product is intended for research and forensic purposes.
Brand:CaymanSKU:19927 -Available on backorder
Metaescaline (hydrochloride) (Item No. 19927) is an analytical reference standard that is structurally classified as a phenethylamine. It is a derivative of escaline (Item No. 14107) in which the single ethyl group is reoriented to the meta position.{31967} This product is intended for research and forensic purposes.
Brand:CaymanSKU:19927 -Available on backorder
Metalaxyl is a fungicide that inhibits protein synthesis in fungi.{43133,42434} It inhibits the growth of potato blight (P. infestans) fungal isolates from Serbian potato fields (EC50s = 0.3-3.9 μg/ml).{43133} Metalaxyl (300 and 1,000 μg/ml) induces formation of chromosomal aberrations in human lymphocytes.{42433} It exhibits aquatic toxicity against S. quadricanda, D. magna, and D. rerio (IC50s = 222.89, 471.95, and 241.98 mg/L, respectively).{42435} Metalaxyl also induces tremors, twitches, tonic extension, ataxia, and hypnosis, symptoms of CNS poisoning, and lethality in rats (LD50s = 265 and 288.8 mg/kg for female and male rats, respectively).{42434}
Brand:CaymanSKU:25817 - 100 mgAvailable on backorder
Metalaxyl is a fungicide that inhibits protein synthesis in fungi.{43133,42434} It inhibits the growth of potato blight (P. infestans) fungal isolates from Serbian potato fields (EC50s = 0.3-3.9 μg/ml).{43133} Metalaxyl (300 and 1,000 μg/ml) induces formation of chromosomal aberrations in human lymphocytes.{42433} It exhibits aquatic toxicity against S. quadricanda, D. magna, and D. rerio (IC50s = 222.89, 471.95, and 241.98 mg/L, respectively).{42435} Metalaxyl also induces tremors, twitches, tonic extension, ataxia, and hypnosis, symptoms of CNS poisoning, and lethality in rats (LD50s = 265 and 288.8 mg/kg for female and male rats, respectively).{42434}
Brand:CaymanSKU:25817 - 50 mgAvailable on backorder
Antigen: metallothionein purified from liver of Atlantic cod (Gadus morhua) · Host: rabbit · Cross-reactivity: (+) Atlantic cod (Gadus morhua), whiting (Merlangius merlangus), yellow gurnard (Trigla lucerna), flounder (Platichthys flesus), cypriniform, siluriform, salmoniform, perciform, and rajiform species metallothionein · Applications: ELISA and WB
Brand:CaymanSKU:172130- 100 µl Brand:CaymanSKU:172130 - 100 µlAvailable on backorder
Antigen: metallothionein purified from liver of Atlantic cod (Gadus morhua) · Host: rabbit · Cross-reactivity: (+) Atlantic cod (Gadus morhua), whiting (Merlangius merlangus), yellow gurnard (Trigla lucerna), flounder (Platichthys flesus), cypriniform, siluriform, salmoniform, perciform, and rajiform species metallothionein · Applications: ELISA and WB
Brand:CaymanSKU:172130- 100 µlAvailable on backorder
Antigen: metallothionein purified from liver of Atlantic cod (Gadus morhua) · Host: rabbit · Cross-reactivity: (+) Atlantic cod (Gadus morhua), whiting (Merlangius merlangus), yellow gurnard (Trigla lucerna), flounder (Platichthys flesus), cypriniform, siluriform, salmoniform, perciform, and rajiform species metallothionein · Applications: ELISA and WB
Brand:CaymanSKU:172130- 500 µl Brand:CaymanSKU:172130 - 500 µlAvailable on backorder
Antigen: metallothionein purified from liver of Atlantic cod (Gadus morhua) · Host: rabbit · Cross-reactivity: (+) Atlantic cod (Gadus morhua), whiting (Merlangius merlangus), yellow gurnard (Trigla lucerna), flounder (Platichthys flesus), cypriniform, siluriform, salmoniform, perciform, and rajiform species metallothionein · Applications: ELISA and WB
Brand:CaymanSKU:172130- 500 µlAvailable on backorder
Metamizole is a nonopioid prodrug that is rapidly hydrolyzed to the analgesic and antipyretic metabolites 4-methylaminoantipyrine (MAA) and 4-aminoantipyrine (AA).{25749} It inhibits COX-1 and COX-2 activity (IC50 = ~150 µg/ml for both in cell-free assays), as well as reduces increases in intracellular calcium levels induced by the TRPA1 agonist AITC in isolated rat and mouse dorsal root ganglia and IMR-90 human fibroblasts (IC50s = 30-91 µM in patch-clamp assays).{46639,46640} Metamizole (6, 12, and 25 µg/ml) inhibits ADP- and epinephrine-induced platelet aggregation in human platelet-rich plasma (hPRP).{46641} It prevents fever induced by LPS, TNF-α, and IL-6, but not arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) or prostaglandin E2 (PGE2; Item No. 14010), in rats when administered at a dose of 120 mg/kg.{46642} Metamizole (250 and 500 mg/kg) increases the paw withdrawal threshold in the paw pressure test, indicating analgesic activity, in rat models of carrageenan-induced acute pain and postoperative incision pain.{46643}
Brand:CaymanSKU:- Metamizole is a nonopioid prodrug that is rapidly hydrolyzed to the analgesic and antipyretic metabolites 4-methylaminoantipyrine (MAA) and 4-aminoantipyrine (AA).{25749} It inhibits COX-1 and COX-2 activity (IC50 = ~150 µg/ml for both in cell-free assays), as well as reduces increases in intracellular calcium levels induced by the TRPA1 agonist AITC in isolated rat and mouse dorsal root ganglia and IMR-90 human fibroblasts (IC50s = 30-91 µM in patch-clamp assays).{46639,46640} Metamizole (6, 12, and 25 µg/ml) inhibits ADP- and epinephrine-induced platelet aggregation in human platelet-rich plasma (hPRP).{46641} It prevents fever induced by LPS, TNF-α, and IL-6, but not arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) or prostaglandin E2 (PGE2; Item No. 14010), in rats when administered at a dose of 120 mg/kg.{46642} Metamizole (250 and 500 mg/kg) increases the paw withdrawal threshold in the paw pressure test, indicating analgesic activity, in rat models of carrageenan-induced acute pain and postoperative incision pain.{46643}
Brand:CaymanSKU:-
Metanephrine is a metabolite of epinephrine produced by the action of catechol-O-methyl transferase on epinephrine.{25427} Determination of plasma or urinary metanephrine is considered the principal test for the clinical diagnosis of pheochromocytoma, an adrenal medullary neuroendocrine tumor.{5331}
Brand:CaymanSKU:- Metanephrine is a metabolite of epinephrine produced by the action of catechol-O-methyl transferase on epinephrine.{25427} Determination of plasma or urinary metanephrine is considered the principal test for the clinical diagnosis of pheochromocytoma, an adrenal medullary neuroendocrine tumor.{5331}
Brand:CaymanSKU:- Metanephrine is a metabolite of epinephrine produced by the action of catechol-O-methyl transferase on epinephrine.{25427} Determination of plasma or urinary metanephrine is considered the principal test for the clinical diagnosis of pheochromocytoma, an adrenal medullary neuroendocrine tumor.{5331}
Brand:CaymanSKU:-
Metaproterenol is a β2-adrenergic receptor (β2-AR) agonist with bronchodilator actions.{40372} It inhibits TGF-α-induced hepatocyte DNA synthesis and proliferation in vitro (IC50 = 15 nM), an effect that is reversed by the β2-AR antagonist butoxamine but not the β1-AR antagonist metoprolol (Item No. 15429).{40371} Metaproterenol dose-dependently relaxes lung strips and increases heart rate and inotropy of right atria and left atria, respectively, isolated from guinea pig (pD2s = 6.4, 7.08, and 6.61, respectively).{40373} Formulations containing metaproterenol were previously used as long-acting bronchodilators for the treatment of asthma.
Brand:CaymanSKU:23611 - 100 mgAvailable on backorder
Metaproterenol is a β2-adrenergic receptor (β2-AR) agonist with bronchodilator actions.{40372} It inhibits TGF-α-induced hepatocyte DNA synthesis and proliferation in vitro (IC50 = 15 nM), an effect that is reversed by the β2-AR antagonist butoxamine but not the β1-AR antagonist metoprolol (Item No. 15429).{40371} Metaproterenol dose-dependently relaxes lung strips and increases heart rate and inotropy of right atria and left atria, respectively, isolated from guinea pig (pD2s = 6.4, 7.08, and 6.61, respectively).{40373} Formulations containing metaproterenol were previously used as long-acting bronchodilators for the treatment of asthma.
Brand:CaymanSKU:23611 - 25 mgAvailable on backorder
Metaproterenol is a β2-adrenergic receptor (β2-AR) agonist with bronchodilator actions.{40372} It inhibits TGF-α-induced hepatocyte DNA synthesis and proliferation in vitro (IC50 = 15 nM), an effect that is reversed by the β2-AR antagonist butoxamine but not the β1-AR antagonist metoprolol (Item No. 15429).{40371} Metaproterenol dose-dependently relaxes lung strips and increases heart rate and inotropy of right atria and left atria, respectively, isolated from guinea pig (pD2s = 6.4, 7.08, and 6.61, respectively).{40373} Formulations containing metaproterenol were previously used as long-acting bronchodilators for the treatment of asthma.
Brand:CaymanSKU:23611 - 50 mgAvailable on backorder
Metaraminol is a vasoconstrictor.{36334,36335} In vivo, metaraminol (0.05 mg/kg) increases cardiac output, mean arterial pressure, and coronary blood flow and decreases pulse rate in a canine model of cardiogenic shock.{36334} It increases survival in a canine model of hemorrhagic hypotension.{36335} Metaraminol also reverses acetoxycycloheximide-induced transient amnesia in a shock avoidance test in rats.{36336}
Brand:CaymanSKU:23938 - 100 mgAvailable on backorder
Metaraminol is a vasoconstrictor.{36334,36335} In vivo, metaraminol (0.05 mg/kg) increases cardiac output, mean arterial pressure, and coronary blood flow and decreases pulse rate in a canine model of cardiogenic shock.{36334} It increases survival in a canine model of hemorrhagic hypotension.{36335} Metaraminol also reverses acetoxycycloheximide-induced transient amnesia in a shock avoidance test in rats.{36336}
Brand:CaymanSKU:23938 - 50 mgAvailable on backorder
Metastin (45-54) is a 10 amino acid peptide that corresponds to the bioactive C-terminal 45-54 amino acids of metastin, a metastasis suppressor gene product.{32826} It acts as a potent agonist of GPR54 (OT7T175, AXOR12), with approximately 8-fold higher binding affinity than metastin (Ki values of 0.042 and 0.34 nM, respectively, for displacement of metastin (40-54)).{32826} Metastin (45-54) induces calcium mobilization in GPR54-transfected cells (EC50 = 0.18-1.1 nM).{32827} It inhibits the migration of GPR54-transfected CHO cells at concentrations of 10-100 nM, equaling the potency of full length metastin.{32825}
Brand:CaymanSKU:20905 -Out of stock
Metastin (45-54) is a 10 amino acid peptide that corresponds to the bioactive C-terminal 45-54 amino acids of metastin, a metastasis suppressor gene product.{32826} It acts as a potent agonist of GPR54 (OT7T175, AXOR12), with approximately 8-fold higher binding affinity than metastin (Ki values of 0.042 and 0.34 nM, respectively, for displacement of metastin (40-54)).{32826} Metastin (45-54) induces calcium mobilization in GPR54-transfected cells (EC50 = 0.18-1.1 nM).{32827} It inhibits the migration of GPR54-transfected CHO cells at concentrations of 10-100 nM, equaling the potency of full length metastin.{32825}
Brand:CaymanSKU:20905 -Out of stock
Metastin (45-54) is a 10 amino acid peptide that corresponds to the bioactive C-terminal 45-54 amino acids of metastin, a metastasis suppressor gene product.{32826} It acts as a potent agonist of GPR54 (OT7T175, AXOR12), with approximately 8-fold higher binding affinity than metastin (Ki values of 0.042 and 0.34 nM, respectively, for displacement of metastin (40-54)).{32826} Metastin (45-54) induces calcium mobilization in GPR54-transfected cells (EC50 = 0.18-1.1 nM).{32827} It inhibits the migration of GPR54-transfected CHO cells at concentrations of 10-100 nM, equaling the potency of full length metastin.{32825}
Brand:CaymanSKU:20905 -Out of stock
Metaxalone is a skeletal muscle relaxant that has applications in reducing muscle spasm, limitations in normal motion, and pain caused by musculoskeletal conditions.{25863,25864,25861} It is commonly used in combination with analgesics to address low back pain.{25862} The molecular or cellular actions of metaxalone is not known.{25863,25862}
Brand:CaymanSKU:- Metaxalone is a skeletal muscle relaxant that has applications in reducing muscle spasm, limitations in normal motion, and pain caused by musculoskeletal conditions.{25863,25864,25861} It is commonly used in combination with analgesics to address low back pain.{25862} The molecular or cellular actions of metaxalone is not known.{25863,25862}
Brand:CaymanSKU:- Metaxalone is a skeletal muscle relaxant that has applications in reducing muscle spasm, limitations in normal motion, and pain caused by musculoskeletal conditions.{25863,25864,25861} It is commonly used in combination with analgesics to address low back pain.{25862} The molecular or cellular actions of metaxalone is not known.{25863,25862}
Brand:CaymanSKU:- Metaxalone is a skeletal muscle relaxant that has applications in reducing muscle spasm, limitations in normal motion, and pain caused by musculoskeletal conditions.{25863,25864,25861} It is commonly used in combination with analgesics to address low back pain.{25862} The molecular or cellular actions of metaxalone is not known.{25863,25862}
Brand:CaymanSKU:-
Metergoline is a serotonin (5-HT) receptor antagonist that is active at 5-HT1 (pKi = 7.8 for 5-HT1B), 5-HT2, (pKi = 8.64, 8.75, and 8.75 for 5-HT2A, 5-HT2B, and 5-HT2C respectively), and 5-HT7 receptor subtypes.{41065,41063} It blocks 5-HT7 receptor-stimulated cAMP production (IC50 = 321 nM) in HEK293 cells.{34420} Metergoline has been widely used to study serotonin receptor function, but it also dose-dependently inhibits voltage-dependent sodium and potassium channels transfected into Xenopus oocytes.{34421,41064} Formulations containing metergoline have been studied for the treatment of hormone dysfunction, seasonal affective disorder, and anxiety.{34421}
Brand:CaymanSKU:21336 -Out of stock
Metergoline is a serotonin (5-HT) receptor antagonist that is active at 5-HT1 (pKi = 7.8 for 5-HT1B), 5-HT2, (pKi = 8.64, 8.75, and 8.75 for 5-HT2A, 5-HT2B, and 5-HT2C respectively), and 5-HT7 receptor subtypes.{41065,41063} It blocks 5-HT7 receptor-stimulated cAMP production (IC50 = 321 nM) in HEK293 cells.{34420} Metergoline has been widely used to study serotonin receptor function, but it also dose-dependently inhibits voltage-dependent sodium and potassium channels transfected into Xenopus oocytes.{34421,41064} Formulations containing metergoline have been studied for the treatment of hormone dysfunction, seasonal affective disorder, and anxiety.{34421}
Brand:CaymanSKU:21336 -Out of stock
Metergoline is a serotonin (5-HT) receptor antagonist that is active at 5-HT1 (pKi = 7.8 for 5-HT1B), 5-HT2, (pKi = 8.64, 8.75, and 8.75 for 5-HT2A, 5-HT2B, and 5-HT2C respectively), and 5-HT7 receptor subtypes.{41065,41063} It blocks 5-HT7 receptor-stimulated cAMP production (IC50 = 321 nM) in HEK293 cells.{34420} Metergoline has been widely used to study serotonin receptor function, but it also dose-dependently inhibits voltage-dependent sodium and potassium channels transfected into Xenopus oocytes.{34421,41064} Formulations containing metergoline have been studied for the treatment of hormone dysfunction, seasonal affective disorder, and anxiety.{34421}
Brand:CaymanSKU:21336 -Out of stock
Metergoline is a serotonin (5-HT) receptor antagonist that is active at 5-HT1 (pKi = 7.8 for 5-HT1B), 5-HT2, (pKi = 8.64, 8.75, and 8.75 for 5-HT2A, 5-HT2B, and 5-HT2C respectively), and 5-HT7 receptor subtypes.{41065,41063} It blocks 5-HT7 receptor-stimulated cAMP production (IC50 = 321 nM) in HEK293 cells.{34420} Metergoline has been widely used to study serotonin receptor function, but it also dose-dependently inhibits voltage-dependent sodium and potassium channels transfected into Xenopus oocytes.{34421,41064} Formulations containing metergoline have been studied for the treatment of hormone dysfunction, seasonal affective disorder, and anxiety.{34421}
Brand:CaymanSKU:21336 -Out of stock
Metformin is a biguanide with diverse biological activities.{21403,13720,43272,43273} Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice.{13720} It reduces weight gain, hepatic lipid droplet content, and total cholesterol, LDL cholesterol, and triglyceride levels in the plasma of diet-induced obese mice when administered at doses of 10 or 50 mg/kg per day.{43273} It also reverses increased hepatic triglyceride and apolipoprotein A5 levels, as well as hepatic steatosis, in a dose-dependent manner in an ob/ob mouse model of non-alcoholic fatty liver disease (NAFLD).{43274} Metformin (250 mg/kg) reduces tumor growth in an HCT116 p53– human colon cancer mouse xenograft model, but has no effect on HCT116 p53– tumors overexpressing recombinant S. cerevisiae Ndi1 NADH dehydrogenase, a single-subunit ortholog of the multi-subunit mammalian mitochondrial complex I.{43272} Formulations containing metformin have been used in the treatment of type 2 diabetes.
Brand:CaymanSKU:- Metformin is a biguanide with diverse biological activities.{21403,13720,43272,43273} Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice.{13720} It reduces weight gain, hepatic lipid droplet content, and total cholesterol, LDL cholesterol, and triglyceride levels in the plasma of diet-induced obese mice when administered at doses of 10 or 50 mg/kg per day.{43273} It also reverses increased hepatic triglyceride and apolipoprotein A5 levels, as well as hepatic steatosis, in a dose-dependent manner in an ob/ob mouse model of non-alcoholic fatty liver disease (NAFLD).{43274} Metformin (250 mg/kg) reduces tumor growth in an HCT116 p53– human colon cancer mouse xenograft model, but has no effect on HCT116 p53– tumors overexpressing recombinant S. cerevisiae Ndi1 NADH dehydrogenase, a single-subunit ortholog of the multi-subunit mammalian mitochondrial complex I.{43272} Formulations containing metformin have been used in the treatment of type 2 diabetes.
Brand:CaymanSKU:-
Metformin-d6 is intended for use as an internal standard for the quantification of metformin (Item No. 13118) by GC- or LC-MS. Metformin is a biguanide with diverse biological activities.{21403,13720,43272,43273} Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice.{13720} It reduces weight gain, hepatic lipid droplet content, and total cholesterol, LDL cholesterol, and triglyceride levels in the plasma of diet-induced obese mice when administered at doses of 10 or 50 mg/kg per day.{43273} It also reverses increased hepatic triglyceride and apolipoprotein A5 levels, as well as hepatic steatosis, in a dose-dependent manner in an ob/ob mouse model of non-alcoholic fatty liver disease (NAFLD).{43274} Metformin (250 mg/kg) reduces tumor growth in an HCT116 p53– human colon cancer mouse xenograft model, but has no effect on HCT116 p53– tumors overexpressing recombinant S. cerevisiae Ndi1 NADH dehydrogenase, a single-subunit ortholog of the multi-subunit mammalian mitochondrial complex I.{43272} Formulations containing metformin have been used in the treatment of type 2 diabetes.
Brand:CaymanSKU:-Out of stock
Metformin-d6 is intended for use as an internal standard for the quantification of metformin (Item No. 13118) by GC- or LC-MS. Metformin is a biguanide with diverse biological activities.{21403,13720,43272,43273} Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice.{13720} It reduces weight gain, hepatic lipid droplet content, and total cholesterol, LDL cholesterol, and triglyceride levels in the plasma of diet-induced obese mice when administered at doses of 10 or 50 mg/kg per day.{43273} It also reverses increased hepatic triglyceride and apolipoprotein A5 levels, as well as hepatic steatosis, in a dose-dependent manner in an ob/ob mouse model of non-alcoholic fatty liver disease (NAFLD).{43274} Metformin (250 mg/kg) reduces tumor growth in an HCT116 p53– human colon cancer mouse xenograft model, but has no effect on HCT116 p53– tumors overexpressing recombinant S. cerevisiae Ndi1 NADH dehydrogenase, a single-subunit ortholog of the multi-subunit mammalian mitochondrial complex I.{43272} Formulations containing metformin have been used in the treatment of type 2 diabetes.
Brand:CaymanSKU:-Out of stock
Metformin-d6 is intended for use as an internal standard for the quantification of metformin (Item No. 13118) by GC- or LC-MS. Metformin is a biguanide with diverse biological activities.{21403,13720,43272,43273} Metformin (250 mg/kg, i.p.) increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice.{13720} It reduces weight gain, hepatic lipid droplet content, and total cholesterol, LDL cholesterol, and triglyceride levels in the plasma of diet-induced obese mice when administered at doses of 10 or 50 mg/kg per day.{43273} It also reverses increased hepatic triglyceride and apolipoprotein A5 levels, as well as hepatic steatosis, in a dose-dependent manner in an ob/ob mouse model of non-alcoholic fatty liver disease (NAFLD).{43274} Metformin (250 mg/kg) reduces tumor growth in an HCT116 p53– human colon cancer mouse xenograft model, but has no effect on HCT116 p53– tumors overexpressing recombinant S. cerevisiae Ndi1 NADH dehydrogenase, a single-subunit ortholog of the multi-subunit mammalian mitochondrial complex I.{43272} Formulations containing metformin have been used in the treatment of type 2 diabetes.
Brand:CaymanSKU:-Out of stock
Methacycline is a tetracycline-class antibiotic that is active against a wide range of Gram-positive and Gram-negative organisms.{33600,33602} It is readily absorbed from the gastrointestinal tract and reaches a maximum concentration at about the fourth hour, declining to a negligible amount in about 24 hours.{33601} It is more active than tetracycline (Item No. 14328) against a number of bacteria.{33600}
Brand:CaymanSKU:21338 -Out of stock
Methacycline is a tetracycline-class antibiotic that is active against a wide range of Gram-positive and Gram-negative organisms.{33600,33602} It is readily absorbed from the gastrointestinal tract and reaches a maximum concentration at about the fourth hour, declining to a negligible amount in about 24 hours.{33601} It is more active than tetracycline (Item No. 14328) against a number of bacteria.{33600}
Brand:CaymanSKU:21338 -Out of stock
Methacycline is a tetracycline-class antibiotic that is active against a wide range of Gram-positive and Gram-negative organisms.{33600,33602} It is readily absorbed from the gastrointestinal tract and reaches a maximum concentration at about the fourth hour, declining to a negligible amount in about 24 hours.{33601} It is more active than tetracycline (Item No. 14328) against a number of bacteria.{33600}
Brand:CaymanSKU:21338 -Out of stock
Methacycline is a tetracycline-class antibiotic that is active against a wide range of Gram-positive and Gram-negative organisms.{33600,33602} It is readily absorbed from the gastrointestinal tract and reaches a maximum concentration at about the fourth hour, declining to a negligible amount in about 24 hours.{33601} It is more active than tetracycline (Item No. 14328) against a number of bacteria.{33600}
Brand:CaymanSKU:21338 -Out of stock
Methazolamide is a carbonic anhydrase inhibitor (IC50 = 130 nM).{36164} It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg.{36165} It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and reduces cerebral edema in a mouse model of SAH.{36166} Methazolamide is larvicidal, with a larvicidal concentration (LC50) value of 724 ppm, but has no activity when administered orally to adult A. aegypti.{36167} Formulations containing methazolamide have been used for the treatment of glaucoma.{36164}
Brand:CaymanSKU:23413 - 1 gAvailable on backorder
Methazolamide is a carbonic anhydrase inhibitor (IC50 = 130 nM).{36164} It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg.{36165} It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and reduces cerebral edema in a mouse model of SAH.{36166} Methazolamide is larvicidal, with a larvicidal concentration (LC50) value of 724 ppm, but has no activity when administered orally to adult A. aegypti.{36167} Formulations containing methazolamide have been used for the treatment of glaucoma.{36164}
Brand:CaymanSKU:23413 - 250 mgAvailable on backorder
Methazolamide is a carbonic anhydrase inhibitor (IC50 = 130 nM).{36164} It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg.{36165} It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and reduces cerebral edema in a mouse model of SAH.{36166} Methazolamide is larvicidal, with a larvicidal concentration (LC50) value of 724 ppm, but has no activity when administered orally to adult A. aegypti.{36167} Formulations containing methazolamide have been used for the treatment of glaucoma.{36164}
Brand:CaymanSKU:23413 - 500 mgAvailable on backorder
Methcathinone (hydrochloride) (exempt preparation) (Item No. 15656) is an analytical reference standard categorized as a psychoactive cathinone. It is a β-ketone analog of methamphetamine and has comparable effects on monoamine uptake.{19757} Methcathinone is regulated as a Schedule I controlled substance in the United States. This product is intended for forensic and research applications only.
Brand:CaymanSKU:-
Methedrone is a phenethylamine, amphetamine, and cathinone derivative that acts as a triple reuptake/release/reversible monoamine oxidase inhibitor. Its use as a recreational drug and its toxicity has recently been reported.{19508,20369} Methedrone is closely related to mephedrone, a psychoactive compound which is regulated in many countries, including the United States. The hydrochloride formulation of this compound is intended for use as a standard for the forensic analysis of samples that may contain methedrone.
Brand:CaymanSKU:10529 - 10 mgAvailable on backorder
Methedrone is a phenethylamine, amphetamine, and cathinone derivative that acts as a triple reuptake/release/reversible monoamine oxidase inhibitor. Its use as a recreational drug and its toxicity has recently been reported.{19508,20369} Methedrone is closely related to mephedrone, a psychoactive compound which is regulated in many countries, including the United States. The hydrochloride formulation of this compound is intended for use as a standard for the forensic analysis of samples that may contain methedrone.
Brand:CaymanSKU:10529 - 5 mgAvailable on backorder
Methedrone is a phenethylamine, amphetamine, and cathinone derivative that acts as a triple reuptake/release/reversible monoamine oxidase inhibitor. Its use as a recreational drug and its toxicity has recently been reported.{19508,20369} Methedrone is closely related to mephedrone, a psychoactive compound which is regulated in many countries, including the United States. The hydrochloride formulation of this compound is intended for use as a standard for the forensic analysis of samples that may contain methedrone.
Brand:CaymanSKU:10529 - 50 mgAvailable on backorder
Methenamine hippurate is a broad-spectrum urinary antiseptic agent.{40517} Under acidic conditions, methenamine hippurate is hydrolyzed to formaldehyde and ammonia, which exerts an antibacterial effect. It is effective against a wide range of bacteria but lacks activity against Proteus and other bacteria that increase urine alkalinity. Formulations containing methenamine hippurate have been used to treat urinary tract infections.
Brand:CaymanSKU:24004 - 100 mgAvailable on backorder
Methenamine hippurate is a broad-spectrum urinary antiseptic agent.{40517} Under acidic conditions, methenamine hippurate is hydrolyzed to formaldehyde and ammonia, which exerts an antibacterial effect. It is effective against a wide range of bacteria but lacks activity against Proteus and other bacteria that increase urine alkalinity. Formulations containing methenamine hippurate have been used to treat urinary tract infections.
Brand:CaymanSKU:24004 - 250 mgAvailable on backorder
Methenamine hippurate is a broad-spectrum urinary antiseptic agent.{40517} Under acidic conditions, methenamine hippurate is hydrolyzed to formaldehyde and ammonia, which exerts an antibacterial effect. It is effective against a wide range of bacteria but lacks activity against Proteus and other bacteria that increase urine alkalinity. Formulations containing methenamine hippurate have been used to treat urinary tract infections.
Brand:CaymanSKU:24004 - 500 mgAvailable on backorder