Cayman
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1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1-palmitoyl-2-hydroxy-sn-glycero-3-PC (Item No. 10172) by GC- or LC-MS. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is the ubiquitous lipid species generated following phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine.{11139} It increases the production of reactive oxygen species (ROS) and decreases superoxide dismutase (SOD) and endothelial nitric oxide synthase (eNOS) protein levels and phosphorylation of ERK1/2 in human umbilical vein endothelial cells (HUVECs) when used at a concentration of 125 µM.{42919} 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC potentiates the secretion of IL-6, IL-1β, IL-12, and TNF-α in LPS-stimulated M1 macrophages, but has no effect on CD163, CD206, CD36, or IL-10 in LPS-stimulated M2 macrophages when used at concentrations of 0.3 and 1.0 µM.{42920} It increases TGF-β1 production and enhances Foxp3 protein levels in Treg cells in isolated human peripheral blood when used at a concentration of 10 µM.{42921} 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC enhances neutrophil function, bacterial clearance, and survival in mouse models of sepsis when administered at a dose of 10 mg/kg.{11693}
Brand:CaymanSKU:28153 - 1 mgAvailable on backorder
1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1-palmitoyl-2-hydroxy-sn-glycero-3-PC (Item No. 10172) by GC- or LC-MS. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is the ubiquitous lipid species generated following phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine.{11139} It increases the production of reactive oxygen species (ROS) and decreases superoxide dismutase (SOD) and endothelial nitric oxide synthase (eNOS) protein levels and phosphorylation of ERK1/2 in human umbilical vein endothelial cells (HUVECs) when used at a concentration of 125 µM.{42919} 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC potentiates the secretion of IL-6, IL-1β, IL-12, and TNF-α in LPS-stimulated M1 macrophages, but has no effect on CD163, CD206, CD36, or IL-10 in LPS-stimulated M2 macrophages when used at concentrations of 0.3 and 1.0 µM.{42920} It increases TGF-β1 production and enhances Foxp3 protein levels in Treg cells in isolated human peripheral blood when used at a concentration of 10 µM.{42921} 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC enhances neutrophil function, bacterial clearance, and survival in mouse models of sepsis when administered at a dose of 10 mg/kg.{11693}
Brand:CaymanSKU:28153 - 5 mgAvailable on backorder
1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1-palmitoyl-2-hydroxy-sn-glycero-3-PC (Item No. 10172) by GC- or LC-MS. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is the ubiquitous lipid species generated following phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine.{11139} It increases the production of reactive oxygen species (ROS) and decreases superoxide dismutase (SOD) and endothelial nitric oxide synthase (eNOS) protein levels and phosphorylation of ERK1/2 in human umbilical vein endothelial cells (HUVECs) when used at a concentration of 125 µM.{42919} 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC potentiates the secretion of IL-6, IL-1β, IL-12, and TNF-α in LPS-stimulated M1 macrophages, but has no effect on CD163, CD206, CD36, or IL-10 in LPS-stimulated M2 macrophages when used at concentrations of 0.3 and 1.0 µM.{42920} It increases TGF-β1 production and enhances Foxp3 protein levels in Treg cells in isolated human peripheral blood when used at a concentration of 10 µM.{42921} 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC enhances neutrophil function, bacterial clearance, and survival in mouse models of sepsis when administered at a dose of 10 mg/kg.{11693} 1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC MaxSpec® standard is a quantitative grade standard of 1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC (Item No. 28153) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Brand:CaymanSKU:30580 - 100 µgAvailable on backorder
1-Palmitoyl-d9-2-palmitoyl-sn-glycerol is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycerol (Item No. 10008648) by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycerol is a diacylglycerol that contains palmitic acid (Item No. 10006627) at the sn-1 and sn-2 positions. It activates protein kinase C (PKC) by 15% when used at a concentration of 25 μM.{15847} 1,2-Dipalmitoyl-sn-glycerol promotes exponential growth of Frankia Gram-positive bacteria.{47378}
Brand:CaymanSKU:27591 - 1 mgAvailable on backorder
1-Palmitoyl-d9-2-palmitoyl-sn-glycerol is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycerol (Item No. 10008648) by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycerol is a diacylglycerol that contains palmitic acid (Item No. 10006627) at the sn-1 and sn-2 positions. It activates protein kinase C (PKC) by 15% when used at a concentration of 25 μM.{15847} 1,2-Dipalmitoyl-sn-glycerol promotes exponential growth of Frankia Gram-positive bacteria.{47378}
Brand:CaymanSKU:27591 - 5 mgAvailable on backorder
1-Palmitoyl-d9-2-palmitoyl-sn-glycerol is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycerol (Item No. 10008648) by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycerol is a diacylglycerol that contains palmitic acid (Item No. 10006627) at the sn-1 and sn-2 positions. It activates protein kinase C (PKC) by 15% when used at a concentration of 25 μM.{15847} 1,2-Dipalmitoyl-sn-glycerol promotes exponential growth of Frankia Gram-positive bacteria.{47378} 1-Palmitoyl-d9-2-palmitoyl-sn-glycerol MaxSpec® standard is a quantitative grade standard of 1-palmitoyl-d9-2-palmitoyl-sn-glycerol (Item No. 27591) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 1-palmitoyl-d9-2-palmitoyl-sn-glycerol MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Brand:CaymanSKU:28781 - 100 µgAvailable on backorder
1-Palmitoyl-rac-glycerol is a monoacylglycerol that contains palmitic acid (Item No. 10006627) at the sn-1 position. It is an emulsifying agent and has been used to increase the viscoelasticity of processed cheese.{49111}
Brand:CaymanSKU:26993 - 100 mgAvailable on backorder
1-Palmitoyl-rac-glycerol is a monoacylglycerol that contains palmitic acid (Item No. 10006627) at the sn-1 position. It is an emulsifying agent and has been used to increase the viscoelasticity of processed cheese.{49111}
Brand:CaymanSKU:26993 - 250 mgAvailable on backorder
1-Palmitoyl-rac-glycerol is a monoacylglycerol that contains palmitic acid (Item No. 10006627) at the sn-1 position. It is an emulsifying agent and has been used to increase the viscoelasticity of processed cheese.{49111}
Brand:CaymanSKU:26993 - 500 mgAvailable on backorder
1-Pentadecanoyl-rac-glycerol is a monoacylglycerol that contains pentadecanoic acid (Item No. 17399) at the sn-1 position. It has been found in wheat bran extracts.{51025} 1-Pentadecanoyl-rac-glycerol levels are increased in a HepaRG cell-based model of hepatic steatosis induced by BSA-conjugated palmitate.{46677}
Brand:CaymanSKU:26959 - 100 mgAvailable on backorder
1-Pentadecanoyl-rac-glycerol is a monoacylglycerol that contains pentadecanoic acid (Item No. 17399) at the sn-1 position. It has been found in wheat bran extracts.{51025} 1-Pentadecanoyl-rac-glycerol levels are increased in a HepaRG cell-based model of hepatic steatosis induced by BSA-conjugated palmitate.{46677}
Brand:CaymanSKU:26959 - 250 mgAvailable on backorder
1-Pentadecanoyl-rac-glycerol is a monoacylglycerol that contains pentadecanoic acid (Item No. 17399) at the sn-1 position. It has been found in wheat bran extracts.{51025} 1-Pentadecanoyl-rac-glycerol levels are increased in a HepaRG cell-based model of hepatic steatosis induced by BSA-conjugated palmitate.{46677}
Brand:CaymanSKU:26959 - 50 mgAvailable on backorder
1-Pentadecanoyl-rac-glycerol is a monoacylglycerol that contains pentadecanoic acid (Item No. 17399) at the sn-1 position. It has been found in wheat bran extracts.{51025} 1-Pentadecanoyl-rac-glycerol levels are increased in a HepaRG cell-based model of hepatic steatosis induced by BSA-conjugated palmitate.{46677}
Brand:CaymanSKU:26959 - 500 mgAvailable on backorder
1-Pyrenesulfonic acid is a fluorescent probe.{47547,47548} It displays absorption/emission maxima of 346/376 nm, respectively.{47546} 1-Pyrenesulfonic acid fluorescence can be quenched by ferric ions and the nitroaromatic compounds and explosive components 2,4-dinitrotoluene (2,4-DNT) and trinitrotoluene (TNT) in aqueous solutions.{47547,47548} It has been used in study of reverse micelles, including intermicellar migration of reactants and in the estimation of the number of micelles per cluster.{47549} 1-Pyrenesulfonic acid has also been used as a surfactant and dopant in the synthesis of polypyrrole micro- and nanowires.{47550}
Brand:CaymanSKU:27983 - 1 gAvailable on backorder
1-Pyrenesulfonic acid is a fluorescent probe.{47547,47548} It displays absorption/emission maxima of 346/376 nm, respectively.{47546} 1-Pyrenesulfonic acid fluorescence can be quenched by ferric ions and the nitroaromatic compounds and explosive components 2,4-dinitrotoluene (2,4-DNT) and trinitrotoluene (TNT) in aqueous solutions.{47547,47548} It has been used in study of reverse micelles, including intermicellar migration of reactants and in the estimation of the number of micelles per cluster.{47549} 1-Pyrenesulfonic acid has also been used as a surfactant and dopant in the synthesis of polypyrrole micro- and nanowires.{47550}
Brand:CaymanSKU:27983 - 500 mgAvailable on backorder
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HETE (Item No. 34720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC; Item No. 10009864) by 15-lipoxygenase (15-LO).{43514}
Brand:CaymanSKU:21138 -Out of stock
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HETE (Item No. 34720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC; Item No. 10009864) by 15-lipoxygenase (15-LO).{43514}
Brand:CaymanSKU:21138 -Out of stock
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HETE (Item No. 34720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC; Item No. 10009864) by 15-lipoxygenase (15-LO).{43514}
Brand:CaymanSKU:21138 -Out of stock
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HETE (Item No. 34720) at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (Item No. 11016) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE; Item No. 25871) by 15-LO.{42427,43514} Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes.
Brand:CaymanSKU:21139 -Out of stock
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HETE (Item No. 34720) at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (Item No. 11016) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE; Item No. 25871) by 15-LO.{42427,43514} Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes.
Brand:CaymanSKU:21139 -Out of stock
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HETE (Item No. 34720) at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (Item No. 11016) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE; Item No. 25871) by 15-LO.{42427,43514} Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes.
Brand:CaymanSKU:21139 -Out of stock
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HETE (Item No. 34720) at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (Item No. 11016) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE; Item No. 25871) by 15-LO.{42427,43514} Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes.
Brand:CaymanSKU:21139 -Out of stock
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HpETE (Item No. 44720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC; Item No. 10009864) by 15-lipoxygenase (15-LO).{43514} 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is toxic to human umbilical vein endothelial cells (HUVECs) when used at a concentration of 100 µM.{3083}
Brand:CaymanSKU:26531 - 100 µgAvailable on backorder
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HpETE (Item No. 44720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC; Item No. 10009864) by 15-lipoxygenase (15-LO).{43514} 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is toxic to human umbilical vein endothelial cells (HUVECs) when used at a concentration of 100 µM.{3083}
Brand:CaymanSKU:26531 - 50 µgAvailable on backorder
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HpETE (Item No. 44720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC; Item No. 10009864) by 15-lipoxygenase (15-LO).{43514} 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is toxic to human umbilical vein endothelial cells (HUVECs) when used at a concentration of 100 µM.{3083}
Brand:CaymanSKU:26531 - 500 µgAvailable on backorder
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HpETE (Item No. 44720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE; Item No. 25871) by 15-lipoxygenase (15-LO).{43514} 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.{33037}
Brand:CaymanSKU:25856 - 1 mgAvailable on backorder
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HpETE (Item No. 44720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE; Item No. 25871) by 15-lipoxygenase (15-LO).{43514} 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.{33037}
Brand:CaymanSKU:25856 - 100 µgAvailable on backorder
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HpETE (Item No. 44720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE; Item No. 25871) by 15-lipoxygenase (15-LO).{43514} 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.{33037}
Brand:CaymanSKU:25856 - 50 µgAvailable on backorder
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HpETE (Item No. 44720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE; Item No. 25871) by 15-lipoxygenase (15-LO).{43514} 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.{33037}
Brand:CaymanSKU:25856 - 500 µgAvailable on backorder
1-Stearoyl-2-arachidonoyl-d8-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (Item No. 10009864) by GC- or LC-MS. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid (Item No. 10011298) and arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques.{17310,53168} Levels of SAPC are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma.{53169} SAPC unilamellar vesicles have been used as substrates to quantify the activity of secretory phospholipase A2 (sPLA2) in the presence or absence of inhibitors.{53170} SAPC has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions.{53171}
Brand:CaymanSKU:10009431 - 1 mgAvailable on backorder
1-Stearoyl-2-arachidonoyl-d8-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (Item No. 10009864) by GC- or LC-MS. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid (Item No. 10011298) and arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques.{17310,53168} Levels of SAPC are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma.{53169} SAPC unilamellar vesicles have been used as substrates to quantify the activity of secretory phospholipase A2 (sPLA2) in the presence or absence of inhibitors.{53170} SAPC has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions.{53171}
Brand:CaymanSKU:10009431 - 100 µgAvailable on backorder
1-Stearoyl-2-arachidonoyl-d8-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (Item No. 10009864) by GC- or LC-MS. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid (Item No. 10011298) and arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques.{17310,53168} Levels of SAPC are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma.{53169} SAPC unilamellar vesicles have been used as substrates to quantify the activity of secretory phospholipase A2 (sPLA2) in the presence or absence of inhibitors.{53170} SAPC has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions.{53171}
Brand:CaymanSKU:10009431 - 50 µgAvailable on backorder
1-Stearoyl-2-arachidonoyl-d8-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (Item No. 10009864) by GC- or LC-MS. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid (Item No. 10011298) and arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques.{17310,53168} Levels of SAPC are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma.{53169} SAPC unilamellar vesicles have been used as substrates to quantify the activity of secretory phospholipase A2 (sPLA2) in the presence or absence of inhibitors.{53170} SAPC has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions.{53171}
Brand:CaymanSKU:10009431 - 500 µgAvailable on backorder
1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid (Item No. 10011298) and arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques.{17310,53168} Levels of SAPC are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma.{53169} SAPC unilamellar vesicles have been used as substrates to quantify the activity of secretory phospholipase A2 (sPLA2) in the presence or absence of inhibitors.{53170} SAPC has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions.{53171}
Brand:CaymanSKU:10009864 - 10 mgAvailable on backorder
1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid (Item No. 10011298) and arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques.{17310,53168} Levels of SAPC are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma.{53169} SAPC unilamellar vesicles have been used as substrates to quantify the activity of secretory phospholipase A2 (sPLA2) in the presence or absence of inhibitors.{53170} SAPC has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions.{53171}
Brand:CaymanSKU:10009864 - 25 mgAvailable on backorder
1-Stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC) is a phospholipid containing stearic acid (Item No. 10011298) and arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques.{17310,53168} Levels of SAPC are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma.{53169} SAPC unilamellar vesicles have been used as substrates to quantify the activity of secretory phospholipase A2 (sPLA2) in the presence or absence of inhibitors.{53170} SAPC has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions.{53171}
Brand:CaymanSKU:10009864 - 5 mgAvailable on backorder
1-Stearoyl-2-arachidonoyl-sn-glycero-3-PE is a naturally-occurring phospholipid that is formed via the phosphatidylserine decarboxylation pathway in mammalian cells.{42426} It has been used in the generation of giant unilamellar vesicles for use in the study of biological membranes.{42428}
Brand:CaymanSKU:25871 - 10 mgAvailable on backorder
1-Stearoyl-2-arachidonoyl-sn-glycero-3-PE is a naturally-occurring phospholipid that is formed via the phosphatidylserine decarboxylation pathway in mammalian cells.{42426} It has been used in the generation of giant unilamellar vesicles for use in the study of biological membranes.{42428}
Brand:CaymanSKU:25871 - 25 mgAvailable on backorder
1-Stearoyl-2-arachidonoyl-sn-glycero-3-PE is a naturally-occurring phospholipid that is formed via the phosphatidylserine decarboxylation pathway in mammalian cells.{42426} It has been used in the generation of giant unilamellar vesicles for use in the study of biological membranes.{42428}
Brand:CaymanSKU:25871 - 5 mgAvailable on backorder
Many protein kinase C (PKC) isoforms require activation via second messengers including Ca2+, diacylglycerol (DAG), and/or a phospholipid to phosphorylate target proteins and they initiate a variety of important signalling cascades.{943} 1-Stearoyl-2-arachidonoyl-sn-glycerol (SAG) is a DAG that contains the ω-6 polyunsaturated fatty acid arachidonic acid in the sn-2 position and stearic acid in the sn-1 position of the glycerol backbone. It can potently activate PKCα, PKCε, and PKCδ at nM concentrations.{15530} Independent of PKC signalling, SAG competitively binds to the Ras activator RasGRP with a Ki value of 4.49 µM in Jurkat T-cells.{15529}
Brand:CaymanSKU:10008650 - 10 mgAvailable on backorder
Many protein kinase C (PKC) isoforms require activation via second messengers including Ca2+, diacylglycerol (DAG), and/or a phospholipid to phosphorylate target proteins and they initiate a variety of important signalling cascades.{943} 1-Stearoyl-2-arachidonoyl-sn-glycerol (SAG) is a DAG that contains the ω-6 polyunsaturated fatty acid arachidonic acid in the sn-2 position and stearic acid in the sn-1 position of the glycerol backbone. It can potently activate PKCα, PKCε, and PKCδ at nM concentrations.{15530} Independent of PKC signalling, SAG competitively binds to the Ras activator RasGRP with a Ki value of 4.49 µM in Jurkat T-cells.{15529}
Brand:CaymanSKU:10008650 - 25 mgAvailable on backorder
Many protein kinase C (PKC) isoforms require activation via second messengers including Ca2+, diacylglycerol (DAG), and/or a phospholipid to phosphorylate target proteins and they initiate a variety of important signalling cascades.{943} 1-Stearoyl-2-arachidonoyl-sn-glycerol (SAG) is a DAG that contains the ω-6 polyunsaturated fatty acid arachidonic acid in the sn-2 position and stearic acid in the sn-1 position of the glycerol backbone. It can potently activate PKCα, PKCε, and PKCδ at nM concentrations.{15530} Independent of PKC signalling, SAG competitively binds to the Ras activator RasGRP with a Ki value of 4.49 µM in Jurkat T-cells.{15529}
Brand:CaymanSKU:10008650 - 5 mgAvailable on backorder
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC is a phospholipid containing stearic acid (Item No. 10011298) and docosahexaenoic acid (DHA; Item No. 90310) at the sn-1 and sn-2 positions, respectively. It has been used in the study of lipid membrane organization and dynamics.{49013} The levels of 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-PC are decreased in the L5 anterior horn in a superoxide dismutase 1 mutant (SODG93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS) at the terminal stage of disease.{49014}
Brand:CaymanSKU:25595 - 10 mgAvailable on backorder
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC is a phospholipid containing stearic acid (Item No. 10011298) and docosahexaenoic acid (DHA; Item No. 90310) at the sn-1 and sn-2 positions, respectively. It has been used in the study of lipid membrane organization and dynamics.{49013} The levels of 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-PC are decreased in the L5 anterior horn in a superoxide dismutase 1 mutant (SODG93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS) at the terminal stage of disease.{49014}
Brand:CaymanSKU:25595 - 25 mgAvailable on backorder
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC is a phospholipid containing stearic acid (Item No. 10011298) and docosahexaenoic acid (DHA; Item No. 90310) at the sn-1 and sn-2 positions, respectively. It has been used in the study of lipid membrane organization and dynamics.{49013} The levels of 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-PC are decreased in the L5 anterior horn in a superoxide dismutase 1 mutant (SODG93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS) at the terminal stage of disease.{49014}
Brand:CaymanSKU:25595 - 5 mgAvailable on backorder
1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated lysophosphatidylcholine. It increases IL-1β production in isolated human blood monocytes when used at a concentration of 12.5 µM.{49237} Plasma levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PC are decreased in patients with lung cancer.{49238}
Brand:CaymanSKU:-1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated lysophosphatidylcholine. It increases IL-1β production in isolated human blood monocytes when used at a concentration of 12.5 µM.{49237} Plasma levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PC are decreased in patients with lung cancer.{49238}
Brand:CaymanSKU:-1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated lysophosphatidylcholine. It increases IL-1β production in isolated human blood monocytes when used at a concentration of 12.5 µM.{49237} Plasma levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PC are decreased in patients with lung cancer.{49238}
Brand:CaymanSKU:-1-Stearoyl-2-hydroxy-sn-glycero-3-PE is a lysophospholipid.{36852} It induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid receptor 1 (LPA1) receptor antagonist AM095 (Item No. 22141).
Brand:CaymanSKU:25593 - 10 mgAvailable on backorder
1-Stearoyl-2-hydroxy-sn-glycero-3-PE is a lysophospholipid.{36852} It induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid receptor 1 (LPA1) receptor antagonist AM095 (Item No. 22141).
Brand:CaymanSKU:25593 - 25 mgAvailable on backorder
1-Stearoyl-2-hydroxy-sn-glycero-3-PE is a lysophospholipid.{36852} It induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid receptor 1 (LPA1) receptor antagonist AM095 (Item No. 22141).
Brand:CaymanSKU:25593 - 5 mgAvailable on backorder
1-Stearoyl-2-hydroxy-sn-glycero-3-PG is a lysophospholipid containing stearic acid (18:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.{33115,33116}
Brand:CaymanSKU:20964 -Out of stock
1-Stearoyl-2-hydroxy-sn-glycero-3-PG is a lysophospholipid containing stearic acid (18:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.{33115,33116}
Brand:CaymanSKU:20964 -Out of stock
1-Stearoyl-2-hydroxy-sn-glycero-3-PG is a lysophospholipid containing stearic acid (18:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.{33115,33116}
Brand:CaymanSKU:20964 -Out of stock
1-Stearoyl-2-hydroxy-sn-glycero-3-PG is a lysophospholipid containing stearic acid (18:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.{33115,33116}
Brand:CaymanSKU:20964 -Out of stock
1-Stearoyl-2-lauroyl-rac-glycerol is a diacylglycerol containing stearic acid (Item No. 10011298) at the sn-1 position and lauric acid (Item No. 10006626) at the sn-2 position. It is a substrate for the rat diacylglycerol lipase DDHD2.{47238}
Brand:CaymanSKU:26883 - 1 mgAvailable on backorder
1-Stearoyl-2-lauroyl-rac-glycerol is a diacylglycerol containing stearic acid (Item No. 10011298) at the sn-1 position and lauric acid (Item No. 10006626) at the sn-2 position. It is a substrate for the rat diacylglycerol lipase DDHD2.{47238}
Brand:CaymanSKU:26883 - 10 mgAvailable on backorder
1-Stearoyl-2-lauroyl-rac-glycerol is a diacylglycerol containing stearic acid (Item No. 10011298) at the sn-1 position and lauric acid (Item No. 10006626) at the sn-2 position. It is a substrate for the rat diacylglycerol lipase DDHD2.{47238}
Brand:CaymanSKU:26883 - 5 mgAvailable on backorder
1-Stearoyl-2-linoleoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid (Item No. 10011298), linoleic acid (Item Nos. 90150 | 90150.1 | 21909), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in poppy seed, maize, and evening primrose oils.{49107}
Brand:CaymanSKU:28562 - 1 mgAvailable on backorder
1-Stearoyl-2-linoleoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid (Item No. 10011298), linoleic acid (Item Nos. 90150 | 90150.1 | 21909), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in poppy seed, maize, and evening primrose oils.{49107}
Brand:CaymanSKU:28562 - 10 mgAvailable on backorder
1-Stearoyl-2-linoleoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid (Item No. 10011298), linoleic acid (Item Nos. 90150 | 90150.1 | 21909), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in poppy seed, maize, and evening primrose oils.{49107}
Brand:CaymanSKU:28562 - 25 mgAvailable on backorder
1-Stearoyl-2-linoleoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid (Item No. 10011298), linoleic acid (Item Nos. 90150 | 90150.1 | 21909), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in poppy seed, maize, and evening primrose oils.{49107}
Brand:CaymanSKU:28562 - 5 mgAvailable on backorder
1-Stearoyl-2-myristoyl-sn-glycero-3-PC (SMPC) belongs to the class of asymmetric phospholipids, which have two chains of unequal length attached to the glycerol backbone. SMPC is abundant in biological membranes where it can interdigitate with equal length (symmetric) acyl chain phospholipids in bilayer membranes to potentially minimize the hydrophobic mismatch between acyl chains.{24290}
Brand:CaymanSKU:-1-Stearoyl-2-myristoyl-sn-glycero-3-PC (SMPC) belongs to the class of asymmetric phospholipids, which have two chains of unequal length attached to the glycerol backbone. SMPC is abundant in biological membranes where it can interdigitate with equal length (symmetric) acyl chain phospholipids in bilayer membranes to potentially minimize the hydrophobic mismatch between acyl chains.{24290}
Brand:CaymanSKU:-1-Stearoyl-2-myristoyl-sn-glycero-3-PC (SMPC) belongs to the class of asymmetric phospholipids, which have two chains of unequal length attached to the glycerol backbone. SMPC is abundant in biological membranes where it can interdigitate with equal length (symmetric) acyl chain phospholipids in bilayer membranes to potentially minimize the hydrophobic mismatch between acyl chains.{24290}
Brand:CaymanSKU:-1-Stearoyl-2-myristoyl-sn-glycero-3-PC (SMPC) belongs to the class of asymmetric phospholipids, which have two chains of unequal length attached to the glycerol backbone. SMPC is abundant in biological membranes where it can interdigitate with equal length (symmetric) acyl chain phospholipids in bilayer membranes to potentially minimize the hydrophobic mismatch between acyl chains.{24290}
Brand:CaymanSKU:-1-Stearoyl-2-oleoyl-3-linoleoyl-rac-glycerol is a triacylglycerol that contains stearic acid (Item No. 10011298), oleic acid (Item Nos. 90260 | 24659), and linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in peanut and soybean oils as well as ostrich and emu oils.{46216,46186} 1-Stearoyl-2-oleoyl-3-linoleoyl-rac-glycerol has been used as a substrate for soybean lipoxygenase in cell-free assays.{46217}
Brand:CaymanSKU:26968 - 10 mgAvailable on backorder
1-Stearoyl-2-oleoyl-3-linoleoyl-rac-glycerol is a triacylglycerol that contains stearic acid (Item No. 10011298), oleic acid (Item Nos. 90260 | 24659), and linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in peanut and soybean oils as well as ostrich and emu oils.{46216,46186} 1-Stearoyl-2-oleoyl-3-linoleoyl-rac-glycerol has been used as a substrate for soybean lipoxygenase in cell-free assays.{46217}
Brand:CaymanSKU:26968 - 25 mgAvailable on backorder
1-Stearoyl-2-oleoyl-3-linoleoyl-rac-glycerol is a triacylglycerol that contains stearic acid (Item No. 10011298), oleic acid (Item Nos. 90260 | 24659), and linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in peanut and soybean oils as well as ostrich and emu oils.{46216,46186} 1-Stearoyl-2-oleoyl-3-linoleoyl-rac-glycerol has been used as a substrate for soybean lipoxygenase in cell-free assays.{46217}
Brand:CaymanSKU:26968 - 50 mgAvailable on backorder
1-Stearoyl-2-palmitoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid (Item No. 10011298) at the sn-1 position, palmitic acid (Item No. 10006627) at the sn-2 position, and oleic acid (Item Nos. 90260 | 24659) at the sn-3 position. It has been found in bovine milk.{46220}
Brand:CaymanSKU:27290 - 10 mgAvailable on backorder
1-Stearoyl-2-palmitoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid (Item No. 10011298) at the sn-1 position, palmitic acid (Item No. 10006627) at the sn-2 position, and oleic acid (Item Nos. 90260 | 24659) at the sn-3 position. It has been found in bovine milk.{46220}
Brand:CaymanSKU:27290 - 25 mgAvailable on backorder
1-Stearoyl-2-palmitoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid (Item No. 10011298) at the sn-1 position, palmitic acid (Item No. 10006627) at the sn-2 position, and oleic acid (Item Nos. 90260 | 24659) at the sn-3 position. It has been found in bovine milk.{46220}
Brand:CaymanSKU:27290 - 5 mgAvailable on backorder
1-Stearoyl-2-palmitoyl-rac-glycerol is a diacylglycerol that contains stearic acid (Item No. 10011298) and palmitic acid (Item No. 10006627) at the sn-1 and sn-2 positions, respectively. It is hydrophobic and has been used, in combination with a surfactant, to increase drug loading and encapsulation efficiency of hydroxypropyl cellulose microcapsules leading to slower drug release in a hydrophilic medium.{42403}
Brand:CaymanSKU:25594 - 1 mgAvailable on backorder
1-Stearoyl-2-palmitoyl-rac-glycerol is a diacylglycerol that contains stearic acid (Item No. 10011298) and palmitic acid (Item No. 10006627) at the sn-1 and sn-2 positions, respectively. It is hydrophobic and has been used, in combination with a surfactant, to increase drug loading and encapsulation efficiency of hydroxypropyl cellulose microcapsules leading to slower drug release in a hydrophilic medium.{42403}
Brand:CaymanSKU:25594 - 10 mgAvailable on backorder
1-Stearoyl-2-palmitoyl-rac-glycerol is a diacylglycerol that contains stearic acid (Item No. 10011298) and palmitic acid (Item No. 10006627) at the sn-1 and sn-2 positions, respectively. It is hydrophobic and has been used, in combination with a surfactant, to increase drug loading and encapsulation efficiency of hydroxypropyl cellulose microcapsules leading to slower drug release in a hydrophilic medium.{42403}
Brand:CaymanSKU:25594 - 5 mgAvailable on backorder
1-Stearoyl-3-arachidoyl-rac-glycerol is a diacylglycerol that contains stearic acid (Item No. 10011298) at the sn-1 position and arachidic acid (Item Nos. 9000339 | 21906) at the sn-3 position.
Brand:CaymanSKU:27284 - 1 mgAvailable on backorder
1-Stearoyl-3-arachidoyl-rac-glycerol is a diacylglycerol that contains stearic acid (Item No. 10011298) at the sn-1 position and arachidic acid (Item Nos. 9000339 | 21906) at the sn-3 position.
Brand:CaymanSKU:27284 - 10 mgAvailable on backorder
1-Stearoyl-3-arachidoyl-rac-glycerol is a diacylglycerol that contains stearic acid (Item No. 10011298) at the sn-1 position and arachidic acid (Item Nos. 9000339 | 21906) at the sn-3 position.
Brand:CaymanSKU:27284 - 5 mgAvailable on backorder
1-Stearoyl-3-linoleoyl-rac-glycerol is a diacylglycerol that contains stearic acid (Item No. 10011298) at the sn-1 position and linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-3 position. Levels of 1-stearoyl-3-linoleoyl-rac-glycerol increase in a time-dependent manner during ripening of dry-cured sausages.{45271}
Brand:CaymanSKU:26830 - 1 mgAvailable on backorder
1-Stearoyl-3-linoleoyl-rac-glycerol is a diacylglycerol that contains stearic acid (Item No. 10011298) at the sn-1 position and linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-3 position. Levels of 1-stearoyl-3-linoleoyl-rac-glycerol increase in a time-dependent manner during ripening of dry-cured sausages.{45271}
Brand:CaymanSKU:26830 - 10 mgAvailable on backorder
1-Stearoyl-3-linoleoyl-rac-glycerol is a diacylglycerol that contains stearic acid (Item No. 10011298) at the sn-1 position and linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-3 position. Levels of 1-stearoyl-3-linoleoyl-rac-glycerol increase in a time-dependent manner during ripening of dry-cured sausages.{45271}
Brand:CaymanSKU:26830 - 5 mgAvailable on backorder