Cayman

Showing 18751–18900 of 45550 results

  • DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer.{22083,22087,22086} Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG), 8-hydroxy-2’-deoxyguanosine (8-OHdG), and 8-hydroxyguanine. Some commercial vendors offer immunoassays that detect only 8-OHdG. Cayman’s DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit is a competitive assay that can be used to measure 8-OHdG, 8-OHG, and 8-hydroxyguanine. Since the antibody used in the assay recognizes damaged nucleic acid species other than 8-OHdG, the value obtained with our assay will be higher than that obtained by competitor ELISAs or by LC/MS analysis that measure a single species. As such, caution is recommended when comparing results obtained from this kit to those obtained by other methods.  

     

    Brand:
    Cayman
    SKU:589320 - 480 solid wells

    Available on backorder

  • DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer.{22083,22087,22086} Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG), 8-hydroxy-2’-deoxyguanosine (8-OHdG), and 8-hydroxyguanine. Some commercial vendors offer immunoassays that detect only 8-OHdG. Cayman’s DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit is a competitive assay that can be used to measure 8-OHdG, 8-OHG, and 8-hydroxyguanine. Since the antibody used in the assay recognizes damaged nucleic acid species other than 8-OHdG, the value obtained with our assay will be higher than that obtained by competitor ELISAs or by LC/MS analysis that measure a single species. As such, caution is recommended when comparing results obtained from this kit to those obtained by other methods.  

     

    Brand:
    Cayman
    SKU:589320 - 480 strip wells

    Available on backorder

  • DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer.{22083,22087,22086} Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG), 8-hydroxy-2’-deoxyguanosine (8-OHdG), and 8-hydroxyguanine. Some commercial vendors offer immunoassays that detect only 8-OHdG. Cayman’s DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit is a competitive assay that can be used to measure 8-OHdG, 8-OHG, and 8-hydroxyguanine. Since the antibody used in the assay recognizes damaged nucleic acid species other than 8-OHdG, the value obtained with our assay will be higher than that obtained by competitor ELISAs or by LC/MS analysis that measure a single species. As such, caution is recommended when comparing results obtained from this kit to those obtained by other methods.  

     

    Brand:
    Cayman
    SKU:589320 - 96 solid wells

    Available on backorder

  • DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer.{22083,22087,22086} Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG), 8-hydroxy-2’-deoxyguanosine (8-OHdG), and 8-hydroxyguanine. Some commercial vendors offer immunoassays that detect only 8-OHdG. Cayman’s DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit is a competitive assay that can be used to measure 8-OHdG, 8-OHG, and 8-hydroxyguanine. Since the antibody used in the assay recognizes damaged nucleic acid species other than 8-OHdG, the value obtained with our assay will be higher than that obtained by competitor ELISAs or by LC/MS analysis that measure a single species. As such, caution is recommended when comparing results obtained from this kit to those obtained by other methods.  

     

    Brand:
    Cayman
    SKU:589320 - 96 strip wells

    Available on backorder

  • Brand:
    Cayman
    SKU:10012603 - 1 ea

    Available on backorder

  • DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM).{40283} It inhibits electron flow from water to NADP or methylviologen by 50 and 100% when used at concentrations of 0.5 or 5 µM, respectively.{40281,40282}  

     

    Brand:
    Cayman
    SKU:9003061 - 1 mg

    Available on backorder

  • DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM).{40283} It inhibits electron flow from water to NADP or methylviologen by 50 and 100% when used at concentrations of 0.5 or 5 µM, respectively.{40281,40282}  

     

    Brand:
    Cayman
    SKU:9003061 - 10 mg

    Available on backorder

  • DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM).{40283} It inhibits electron flow from water to NADP or methylviologen by 50 and 100% when used at concentrations of 0.5 or 5 µM, respectively.{40281,40282}  

     

    Brand:
    Cayman
    SKU:9003061 - 25 mg

    Available on backorder

  • DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM).{40283} It inhibits electron flow from water to NADP or methylviologen by 50 and 100% when used at concentrations of 0.5 or 5 µM, respectively.{40281,40282}  

     

    Brand:
    Cayman
    SKU:9003061 - 5 mg

    Available on backorder

  • Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9.{38801} Upon cleavage by MMP-1 or MMP-9, N-methylanthranilic acid (Nma) is unquenched and its fluorescence can be used to quantify MMP activity. Nma displays excitation/emission spectra of 340/440 nm, respectively.  

     

    Brand:
    Cayman
    SKU:24709 - 1 mg

    Available on backorder

  • Dnp-PYAYWMR is a fluorgenic heptapeptide substrate for matrix metalloproteinase-8 (MMP-8).{40722} MMP-8 activity can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis that removes the N-terminal dinitrophenol (DNP) group.  

     

    Brand:
    Cayman
    SKU:24538 - 1 mg

    Available on backorder

  • DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively versus IC50 = 40 μM for NMDA receptors).{23070,23071,23072} This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-term potentiation in the hippocampus.{23069}  

     

    Brand:
    Cayman
    SKU:-
  • DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively versus IC50 = 40 μM for NMDA receptors).{23070,23071,23072} This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-term potentiation in the hippocampus.{23069}  

     

    Brand:
    Cayman
    SKU:-
  • DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively versus IC50 = 40 μM for NMDA receptors).{23070,23071,23072} This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-term potentiation in the hippocampus.{23069}  

     

    Brand:
    Cayman
    SKU:-
  • DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively versus IC50 = 40 μM for NMDA receptors).{23070,23071,23072} This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-term potentiation in the hippocampus.{23069}  

     

    Brand:
    Cayman
    SKU:-
  • DO264 is an inhibitor of α/β-hydrolase domain-containing protein 12 (ABHD12; IC50 = 11 nM).{45704} It inhibits ABHD12-dependent hydrolysis of lysophosphatidylserine (lyso-PS) in mouse brain membrane lysates (IC50 = 2.8 nM) and human THP-1 cells.{45705} DO264 increases levels of chemokine (C-C motif) ligand 3 (CCL3), CCL4, TNF-α, and IL-1β in M1-polarized THP-1 macrophages. It potentiates ferroptotic cell death induced by the glutathione peroxidase 4 (GPX4) inhibitor RSL3 in HT1080 fibrosarcoma and SU-DHL-5 B cell lymphoma cells when used at a concentration of 1 μM.{45704,49606} In vivo, DO264 (30 mg/kg per day for four weeks) increases levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PS, 1-arachidonoyl-2-hydroxy-sn-glycero-3-PS, 1-docosanoyl-2-hydroxy-sn-glycero-3-PS, 1-stearoyl-2-arachidonoyl-sn-glycero-3-PS, and 1-oleoyl-2-arachidonoyl-sn-glycero-3-PS in mouse brain.{45705} It increases levels of CCL2, CCL3, and CCL5 in bronchoalveolar lavage fluid (BALF) and decreases survival in a mouse model of infection with lymphocytic choriomeningitis virus (LCMV) clone 13 when administered at a dose of 30 mg/kg.  

     

    Brand:
    Cayman
    SKU:29402 - 1 mg

    Available on backorder

  • DO264 is an inhibitor of α/β-hydrolase domain-containing protein 12 (ABHD12; IC50 = 11 nM).{45704} It inhibits ABHD12-dependent hydrolysis of lysophosphatidylserine (lyso-PS) in mouse brain membrane lysates (IC50 = 2.8 nM) and human THP-1 cells.{45705} DO264 increases levels of chemokine (C-C motif) ligand 3 (CCL3), CCL4, TNF-α, and IL-1β in M1-polarized THP-1 macrophages. It potentiates ferroptotic cell death induced by the glutathione peroxidase 4 (GPX4) inhibitor RSL3 in HT1080 fibrosarcoma and SU-DHL-5 B cell lymphoma cells when used at a concentration of 1 μM.{45704,49606} In vivo, DO264 (30 mg/kg per day for four weeks) increases levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PS, 1-arachidonoyl-2-hydroxy-sn-glycero-3-PS, 1-docosanoyl-2-hydroxy-sn-glycero-3-PS, 1-stearoyl-2-arachidonoyl-sn-glycero-3-PS, and 1-oleoyl-2-arachidonoyl-sn-glycero-3-PS in mouse brain.{45705} It increases levels of CCL2, CCL3, and CCL5 in bronchoalveolar lavage fluid (BALF) and decreases survival in a mouse model of infection with lymphocytic choriomeningitis virus (LCMV) clone 13 when administered at a dose of 30 mg/kg.  

     

    Brand:
    Cayman
    SKU:29402 - 10 mg

    Available on backorder

  • DO264 is an inhibitor of α/β-hydrolase domain-containing protein 12 (ABHD12; IC50 = 11 nM).{45704} It inhibits ABHD12-dependent hydrolysis of lysophosphatidylserine (lyso-PS) in mouse brain membrane lysates (IC50 = 2.8 nM) and human THP-1 cells.{45705} DO264 increases levels of chemokine (C-C motif) ligand 3 (CCL3), CCL4, TNF-α, and IL-1β in M1-polarized THP-1 macrophages. It potentiates ferroptotic cell death induced by the glutathione peroxidase 4 (GPX4) inhibitor RSL3 in HT1080 fibrosarcoma and SU-DHL-5 B cell lymphoma cells when used at a concentration of 1 μM.{45704,49606} In vivo, DO264 (30 mg/kg per day for four weeks) increases levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PS, 1-arachidonoyl-2-hydroxy-sn-glycero-3-PS, 1-docosanoyl-2-hydroxy-sn-glycero-3-PS, 1-stearoyl-2-arachidonoyl-sn-glycero-3-PS, and 1-oleoyl-2-arachidonoyl-sn-glycero-3-PS in mouse brain.{45705} It increases levels of CCL2, CCL3, and CCL5 in bronchoalveolar lavage fluid (BALF) and decreases survival in a mouse model of infection with lymphocytic choriomeningitis virus (LCMV) clone 13 when administered at a dose of 30 mg/kg.  

     

    Brand:
    Cayman
    SKU:29402 - 5 mg

    Available on backorder

  • DOAM (Item No. 17656) is an analytical reference standard that is structurally categorized as an amphetamine. Experiments with isolated rat thoracic aorta suggested that this compound may act as an antagonist of the 5-HT2 receptor.{30477} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • DOAM (Item No. 17656) is an analytical reference standard that is structurally categorized as an amphetamine. Experiments with isolated rat thoracic aorta suggested that this compound may act as an antagonist of the 5-HT2 receptor.{30477} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • DOAM (Item No. 17656) is an analytical reference standard that is structurally categorized as an amphetamine. Experiments with isolated rat thoracic aorta suggested that this compound may act as an antagonist of the 5-HT2 receptor.{30477} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • DOBU (Item No. 17655) is an analytical reference standard that is structurally categorized as an amphetamine. Experiments with isolated rat thoracic aorta suggested that this compound may act as an antagonist of the 5-HT2 receptor.{30477} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • DOBU (Item No. 17655) is an analytical reference standard that is structurally categorized as an amphetamine. Experiments with isolated rat thoracic aorta suggested that this compound may act as an antagonist of the 5-HT2 receptor.{30477} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • DOBU (Item No. 17655) is an analytical reference standard that is structurally categorized as an amphetamine. Experiments with isolated rat thoracic aorta suggested that this compound may act as an antagonist of the 5-HT2 receptor.{30477} This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • Dobutamine is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects in vivo.{25418,25421,25419} It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions.{25418,25421} As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects.{25418} Dobutamine is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1 μM.{25420}  

     

    Brand:
    Cayman
    SKU:-
  • Dobutamine is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects in vivo.{25418,25421,25419} It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions.{25418,25421} As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects.{25418} Dobutamine is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1 μM.{25420}  

     

    Brand:
    Cayman
    SKU:-
  • Dobutamine is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects in vivo.{25418,25421,25419} It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions.{25418,25421} As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects.{25418} Dobutamine is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1 μM.{25420}  

     

    Brand:
    Cayman
    SKU:-
  • Dobutamine is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects in vivo.{25418,25421,25419} It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions.{25418,25421} As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects.{25418} Dobutamine is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1 μM.{25420}  

     

    Brand:
    Cayman
    SKU:-
  • Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM).{20977} It has proven more effective than taxol in preventing the proliferation of cancer cells.{20977,20979} Docetaxel has applications in breast cancer and hormone-refractory prostate cancer.{20980,20978} This product is intended for research applications.  

     

    Brand:
    Cayman
    SKU:11637 - 10 mg

    Available on backorder

  • Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM).{20977} It has proven more effective than taxol in preventing the proliferation of cancer cells.{20977,20979} Docetaxel has applications in breast cancer and hormone-refractory prostate cancer.{20980,20978} This product is intended for research applications.  

     

    Brand:
    Cayman
    SKU:11637 - 250 mg

    Available on backorder

  • Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM).{20977} It has proven more effective than taxol in preventing the proliferation of cancer cells.{20977,20979} Docetaxel has applications in breast cancer and hormone-refractory prostate cancer.{20980,20978} This product is intended for research applications.  

     

    Brand:
    Cayman
    SKU:11637 - 5 mg

    Available on backorder

  • Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM).{20977} It has proven more effective than taxol in preventing the proliferation of cancer cells.{20977,20979} Docetaxel has applications in breast cancer and hormone-refractory prostate cancer.{20980,20978} This product is intended for research applications.  

     

    Brand:
    Cayman
    SKU:11637 - 50 mg

    Available on backorder

  • Docetaxel-d9 is intended for use as an internal standard for the quantification of docetaxel (Item No. 11637) by GC- or LC-MS. Docetaxel is a semisynthetic analog of paclitaxel (Item No. 10461) that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM).{20977} It has proven more effective than taxol in preventing the proliferation of cancer cells.{20977,20979} Docetaxel has potential applications in breast cancer and hormone-refractory prostate cancer.{20980,20978}  

     

    Brand:
    Cayman
    SKU:22094 -

    Out of stock

  • Docetaxel-d9 is intended for use as an internal standard for the quantification of docetaxel (Item No. 11637) by GC- or LC-MS. Docetaxel is a semisynthetic analog of paclitaxel (Item No. 10461) that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM).{20977} It has proven more effective than taxol in preventing the proliferation of cancer cells.{20977,20979} Docetaxel has potential applications in breast cancer and hormone-refractory prostate cancer.{20980,20978}  

     

    Brand:
    Cayman
    SKU:22094 -

    Out of stock

  • Docosadienoic acid methyl ester is an esterified version of 13Z,16Z-docosadienoic acid (Item No. 20749), which is a natural ω-6 polyunsaturated fatty acid (PUFA). Docosadienoic acid is an agonist of free fatty acid receptor 4 (FFAR4, also known as GPR120) and strongly inhibits the secretion of ghrelin by isolated mouse gastric cells.{32737}  

     

    Brand:
    Cayman
    SKU:20602 -

    Available on backorder

  • Docosadienoic acid methyl ester is an esterified version of 13Z,16Z-docosadienoic acid (Item No. 20749), which is a natural ω-6 polyunsaturated fatty acid (PUFA). Docosadienoic acid is an agonist of free fatty acid receptor 4 (FFAR4, also known as GPR120) and strongly inhibits the secretion of ghrelin by isolated mouse gastric cells.{32737}  

     

    Brand:
    Cayman
    SKU:20602 -

    Available on backorder

  • Docosadienoic acid methyl ester is an esterified version of 13Z,16Z-docosadienoic acid (Item No. 20749), which is a natural ω-6 polyunsaturated fatty acid (PUFA). Docosadienoic acid is an agonist of free fatty acid receptor 4 (FFAR4, also known as GPR120) and strongly inhibits the secretion of ghrelin by isolated mouse gastric cells.{32737}  

     

    Brand:
    Cayman
    SKU:20602 -

    Available on backorder

  • Docosaenoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids.{1202,1712,13153} This long-chain ethanolamine has been detected at relatively high levels in rat cerebrospinal fluid and has been used to examine the function of voltage-dependent Ca2+ channels in skeletal muscle membranes.{22439,13759}  

     

    Brand:
    Cayman
    SKU:9001745 - 10 mg

    Available on backorder

  • Docosaenoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids.{1202,1712,13153} This long-chain ethanolamine has been detected at relatively high levels in rat cerebrospinal fluid and has been used to examine the function of voltage-dependent Ca2+ channels in skeletal muscle membranes.{22439,13759}  

     

    Brand:
    Cayman
    SKU:9001745 - 5 mg

    Available on backorder

  • Docosaenoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids.{1202,1712,13153} This long-chain ethanolamine has been detected at relatively high levels in rat cerebrospinal fluid and has been used to examine the function of voltage-dependent Ca2+ channels in skeletal muscle membranes.{22439,13759}  

     

    Brand:
    Cayman
    SKU:9001745 - 50 mg

    Available on backorder

  • DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}  

     

    Brand:
    Cayman
    SKU:90310 - 100 mg

    Available on backorder

  • DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}  

     

    Brand:
    Cayman
    SKU:90310 - 250 mg

    Available on backorder

  • DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}  

     

    Brand:
    Cayman
    SKU:90310 - 50 mg

    Available on backorder

  • DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}  

     

    Brand:
    Cayman
    SKU:90310 - 500 mg

    Available on backorder

  • Fish oils in the diet have anti-inflammatory and cardiovascular benefits due to an abundance of ω-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA).{16509} DHA is the most abundant ω-3 PUFA in neural tissues, especially in the retina and brain. DHA ethyl ester is the stabilized ethyl ester form of the ω-3 22:6 fatty acid. Dietary intake of DHA ethyl ester enhances maze-learning ability in old mice.{16512} In rats, dietary DHA ethyl ester increases plasma and erythrocyte membrane DHA levels without altering the content of the ω-6 arachidonic acid.{16510} Dietary DHA ethyl ester increases fatty acid oxidation enzymes in rats and, in humans with peroxisomal disorders, improves vision, liver function, muscle tone, and social contact.{16514,16511} The ω-3 fatty acid eicosapentaenoic acid competitively inhibits the metabolism of arachidonic acid by COX enzymes, suggesting that DHA ethyl ester may also directly modulate the actions of enzymes involved in fatty acid metabolism.{16250}  

     

    Brand:
    Cayman
    SKU:9090310 - 1 g

    Available on backorder

  • Fish oils in the diet have anti-inflammatory and cardiovascular benefits due to an abundance of ω-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA).{16509} DHA is the most abundant ω-3 PUFA in neural tissues, especially in the retina and brain. DHA ethyl ester is the stabilized ethyl ester form of the ω-3 22:6 fatty acid. Dietary intake of DHA ethyl ester enhances maze-learning ability in old mice.{16512} In rats, dietary DHA ethyl ester increases plasma and erythrocyte membrane DHA levels without altering the content of the ω-6 arachidonic acid.{16510} Dietary DHA ethyl ester increases fatty acid oxidation enzymes in rats and, in humans with peroxisomal disorders, improves vision, liver function, muscle tone, and social contact.{16514,16511} The ω-3 fatty acid eicosapentaenoic acid competitively inhibits the metabolism of arachidonic acid by COX enzymes, suggesting that DHA ethyl ester may also directly modulate the actions of enzymes involved in fatty acid metabolism.{16250}  

     

    Brand:
    Cayman
    SKU:9090310 - 100 mg

    Available on backorder

  • Fish oils in the diet have anti-inflammatory and cardiovascular benefits due to an abundance of ω-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA).{16509} DHA is the most abundant ω-3 PUFA in neural tissues, especially in the retina and brain. DHA ethyl ester is the stabilized ethyl ester form of the ω-3 22:6 fatty acid. Dietary intake of DHA ethyl ester enhances maze-learning ability in old mice.{16512} In rats, dietary DHA ethyl ester increases plasma and erythrocyte membrane DHA levels without altering the content of the ω-6 arachidonic acid.{16510} Dietary DHA ethyl ester increases fatty acid oxidation enzymes in rats and, in humans with peroxisomal disorders, improves vision, liver function, muscle tone, and social contact.{16514,16511} The ω-3 fatty acid eicosapentaenoic acid competitively inhibits the metabolism of arachidonic acid by COX enzymes, suggesting that DHA ethyl ester may also directly modulate the actions of enzymes involved in fatty acid metabolism.{16250}  

     

    Brand:
    Cayman
    SKU:9090310 - 50 mg

    Available on backorder

  • Fish oils in the diet have anti-inflammatory and cardiovascular benefits due to an abundance of ω-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA).{16509} DHA is the most abundant ω-3 PUFA in neural tissues, especially in the retina and brain. DHA ethyl ester is the stabilized ethyl ester form of the ω-3 22:6 fatty acid. Dietary intake of DHA ethyl ester enhances maze-learning ability in old mice.{16512} In rats, dietary DHA ethyl ester increases plasma and erythrocyte membrane DHA levels without altering the content of the ω-6 arachidonic acid.{16510} Dietary DHA ethyl ester increases fatty acid oxidation enzymes in rats and, in humans with peroxisomal disorders, improves vision, liver function, muscle tone, and social contact.{16514,16511} The ω-3 fatty acid eicosapentaenoic acid competitively inhibits the metabolism of arachidonic acid by COX enzymes, suggesting that DHA ethyl ester may also directly modulate the actions of enzymes involved in fatty acid metabolism.{16250}  

     

    Brand:
    Cayman
    SKU:9090310 - 500 mg

    Available on backorder

  • Docosahexaenoic acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856} DHA MaxSpec® standard is a quantitative grade standard of DHA (Item No. 90310) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This DHA MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.  

     

    Brand:
    Cayman
    SKU:26414 - 1 mg

    Available on backorder

  • Docosahexaenoic acid (DHA) methyl ester is an esterified form of DHA (Item No. 90310). It has been used as a reference standard in the quantification of fatty acids in microalgal and fish oils.{54169}  

     

    Brand:
    Cayman
    SKU:10006865 - 1 g

    Available on backorder

  • Docosahexaenoic acid (DHA) methyl ester is an esterified form of DHA (Item No. 90310). It has been used as a reference standard in the quantification of fatty acids in microalgal and fish oils.{54169}  

     

    Brand:
    Cayman
    SKU:10006865 - 100 mg

    Available on backorder

  • Docosahexaenoic acid (DHA) methyl ester is an esterified form of DHA (Item No. 90310). It has been used as a reference standard in the quantification of fatty acids in microalgal and fish oils.{54169}  

     

    Brand:
    Cayman
    SKU:10006865 - 50 mg

    Available on backorder

  • Docosahexaenoic acid (DHA) methyl ester is an esterified form of DHA (Item No. 90310). It has been used as a reference standard in the quantification of fatty acids in microalgal and fish oils.{54169}  

     

    Brand:
    Cayman
    SKU:10006865 - 500 mg

    Available on backorder

  • Docosahexaenoic Acid-d5 (DHA-d5) contains five deuterium atoms at the 21, 21, 22, 22 and 22 positions. It is intended for use as an internal standard for the quantification of DHA (Item No. 90310) by GC- or LC-mass spectrometry. DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total polyunsaturated fatty acid pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}  

     

    Brand:
    Cayman
    SKU:10005057 - 1 mg

    Available on backorder

  • Docosahexaenoic Acid-d5 (DHA-d5) contains five deuterium atoms at the 21, 21, 22, 22 and 22 positions. It is intended for use as an internal standard for the quantification of DHA (Item No. 90310) by GC- or LC-mass spectrometry. DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total polyunsaturated fatty acid pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}  

     

    Brand:
    Cayman
    SKU:10005057 - 100 µg

    Available on backorder

  • Docosahexaenoic Acid-d5 (DHA-d5) contains five deuterium atoms at the 21, 21, 22, 22 and 22 positions. It is intended for use as an internal standard for the quantification of DHA (Item No. 90310) by GC- or LC-mass spectrometry. DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total polyunsaturated fatty acid pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}  

     

    Brand:
    Cayman
    SKU:10005057 - 50 µg

    Available on backorder

  • Docosahexaenoic Acid-d5 (DHA-d5) contains five deuterium atoms at the 21, 21, 22, 22 and 22 positions. It is intended for use as an internal standard for the quantification of DHA (Item No. 90310) by GC- or LC-mass spectrometry. DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total polyunsaturated fatty acid pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}  

     

    Brand:
    Cayman
    SKU:10005057 - 500 µg

    Available on backorder

  • Docosahexaenoic acid-d5 (DHA-d5) is intended for use as an internal standard for the quantification of DHA (Item No. 90310) by GC- or LC-MS. DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain.{10297} DHA constitutes as much as 40% of the total polyunsaturated fatty acid pool in retinal and neuronal membranes. Neonatal DHA deprivation leads to developmental defects and can lead to hypertension in rats.{8856} DHA-d5 MaxSpec® standard is a quantitative grade standard of DHA-d5 (Item No. 10005057) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This DHA-d5 MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.  

     

    Brand:
    Cayman
    SKU:27357 - 100 µg

    Available on backorder

  • Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with docosahexaenoic acid (DHA) compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki of 324 nM, which is approximately 10-fold higher than the Ki for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 of 1.5 µM.{13859}  

     

    Brand:
    Cayman
    SKU:10007534 - 10 mg

    Available on backorder

  • Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with docosahexaenoic acid (DHA) compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki of 324 nM, which is approximately 10-fold higher than the Ki for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 of 1.5 µM.{13859}  

     

    Brand:
    Cayman
    SKU:10007534 - 25 mg

    Available on backorder

  • Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with docosahexaenoic acid (DHA) compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki of 324 nM, which is approximately 10-fold higher than the Ki for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 of 1.5 µM.{13859}  

     

    Brand:
    Cayman
    SKU:10007534 - 5 mg

    Available on backorder

  • Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with docosahexaenoic acid (DHA) compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki of 324 nM, which is approximately 10-fold higher than the Ki for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 of 1.5 µM.{13859}  

     

    Brand:
    Cayman
    SKU:10007534 - 50 mg

    Available on backorder

  • Docosahexaenoyl ethanolamide-d4 contains four deuterium atoms at the 1, 1′, 2, and 2′ positions. It is intended for use as an internal standard for the quantification of docosahexaenoyl ethanolamide by GC- or LC-mass spectrometry (MS). Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with DHA compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki value of 324 nM, which is approximately 10-fold higher than the Ki value for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 value of 1.5 µM.{13859}  

     

    Brand:
    Cayman
    SKU:9001108 - 1 mg

    Available on backorder

  • Docosahexaenoyl ethanolamide-d4 contains four deuterium atoms at the 1, 1′, 2, and 2′ positions. It is intended for use as an internal standard for the quantification of docosahexaenoyl ethanolamide by GC- or LC-mass spectrometry (MS). Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with DHA compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki value of 324 nM, which is approximately 10-fold higher than the Ki value for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 value of 1.5 µM.{13859}  

     

    Brand:
    Cayman
    SKU:9001108 - 10 mg

    Available on backorder

  • Docosahexaenoyl ethanolamide-d4 contains four deuterium atoms at the 1, 1′, 2, and 2′ positions. It is intended for use as an internal standard for the quantification of docosahexaenoyl ethanolamide by GC- or LC-mass spectrometry (MS). Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with DHA compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki value of 324 nM, which is approximately 10-fold higher than the Ki value for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 value of 1.5 µM.{13859}  

     

    Brand:
    Cayman
    SKU:9001108 - 5 mg

    Available on backorder

  • Docosahexaenoyl ethanolamide-d4 contains four deuterium atoms at the 1, 1′, 2, and 2′ positions. It is intended for use as an internal standard for the quantification of docosahexaenoyl ethanolamide by GC- or LC-mass spectrometry (MS). Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with DHA compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki value of 324 nM, which is approximately 10-fold higher than the Ki value for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 value of 1.5 µM.{13859}  

     

    Brand:
    Cayman
    SKU:9001108 - 500 µg

    Available on backorder

  • The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Docosahexaenoic acid (DHA), a C22:6 PUFA, is the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. It can be synthesized from other dietary ω-3 PUFAs or taken as a nutritional supplement. Docosahexaenoyl glycine consists of DHA with glycine attached at its carboxy terminus.  

     

    Brand:
    Cayman
    SKU:9000328 - 10 mg

    Available on backorder

  • The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Docosahexaenoic acid (DHA), a C22:6 PUFA, is the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. It can be synthesized from other dietary ω-3 PUFAs or taken as a nutritional supplement. Docosahexaenoyl glycine consists of DHA with glycine attached at its carboxy terminus.  

     

    Brand:
    Cayman
    SKU:9000328 - 100 mg

    Available on backorder

  • The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Docosahexaenoic acid (DHA), a C22:6 PUFA, is the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. It can be synthesized from other dietary ω-3 PUFAs or taken as a nutritional supplement. Docosahexaenoyl glycine consists of DHA with glycine attached at its carboxy terminus.  

     

    Brand:
    Cayman
    SKU:9000328 - 5 mg

    Available on backorder

  • The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Docosahexaenoic acid (DHA), a C22:6 PUFA, is the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. It can be synthesized from other dietary ω-3 PUFAs or taken as a nutritional supplement. Docosahexaenoyl glycine consists of DHA with glycine attached at its carboxy terminus.  

     

    Brand:
    Cayman
    SKU:9000328 - 50 mg

    Available on backorder

  • Docosahexaenoyl PAF C-16 is a PAF analog which contains docosahexaenoate at the sn-2 position rather than the acetate moiety found in PAF C-16. Docosahexaenoyl PAF C-16 can be oxidatively fragmented resulting in the production of phospholipids with PAF-like activity.{1938,2654}  

     

    Brand:
    Cayman
    SKU:60903 - 1 mg

    Available on backorder

  • Docosahexaenoyl PAF C-16 is a PAF analog which contains docosahexaenoate at the sn-2 position rather than the acetate moiety found in PAF C-16. Docosahexaenoyl PAF C-16 can be oxidatively fragmented resulting in the production of phospholipids with PAF-like activity.{1938,2654}  

     

    Brand:
    Cayman
    SKU:60903 - 10 mg

    Available on backorder

  • Docosahexaenoyl PAF C-16 is a PAF analog which contains docosahexaenoate at the sn-2 position rather than the acetate moiety found in PAF C-16. Docosahexaenoyl PAF C-16 can be oxidatively fragmented resulting in the production of phospholipids with PAF-like activity.{1938,2654}  

     

    Brand:
    Cayman
    SKU:60903 - 25 mg

    Available on backorder

  • Docosahexaenoyl PAF C-16 is a PAF analog which contains docosahexaenoate at the sn-2 position rather than the acetate moiety found in PAF C-16. Docosahexaenoyl PAF C-16 can be oxidatively fragmented resulting in the production of phospholipids with PAF-like activity.{1938,2654}  

     

    Brand:
    Cayman
    SKU:60903 - 5 mg

    Available on backorder

  • Docosahexaenoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (Catalog No. 70665). Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid 1 (TRPV1) channel, reducing both acute and chronic peripheral pain.{18121,18122} The effects of replacing the arachidonoyl portion with docosahexaenoyl have not been studied.  

     

    Brand:
    Cayman
    SKU:9000639 - 10 mg

    Available on backorder

  • Docosahexaenoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (Catalog No. 70665). Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid 1 (TRPV1) channel, reducing both acute and chronic peripheral pain.{18121,18122} The effects of replacing the arachidonoyl portion with docosahexaenoyl have not been studied.  

     

    Brand:
    Cayman
    SKU:9000639 - 100 mg

    Available on backorder

  • Docosahexaenoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (Catalog No. 70665). Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid 1 (TRPV1) channel, reducing both acute and chronic peripheral pain.{18121,18122} The effects of replacing the arachidonoyl portion with docosahexaenoyl have not been studied.  

     

    Brand:
    Cayman
    SKU:9000639 - 5 mg

    Available on backorder

  • Docosahexaenoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (Catalog No. 70665). Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid 1 (TRPV1) channel, reducing both acute and chronic peripheral pain.{18121,18122} The effects of replacing the arachidonoyl portion with docosahexaenoyl have not been studied.  

     

    Brand:
    Cayman
    SKU:9000639 - 50 mg

    Available on backorder

  • Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.{48322,48323} It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM).{31533} Docosanoic acid inhibits rat DNA polymerase β and human DNA polymerase λ activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM.{39264} Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet but not a high-cholesterol diet.{48324} Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.  

     

    Brand:
    Cayman
    SKU:9000338 - 1 g

    Available on backorder

  • Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.{48322,48323} It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM).{31533} Docosanoic acid inhibits rat DNA polymerase β and human DNA polymerase λ activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM.{39264} Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet but not a high-cholesterol diet.{48324} Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.  

     

    Brand:
    Cayman
    SKU:9000338 - 5 g

    Available on backorder

  • Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.{48322,48323} It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM).{31533} Docosanoic acid inhibits rat DNA polymerase β and human DNA polymerase λ activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM.{39264} Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet but not a high-cholesterol diet.{48324} Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.  

     

    Brand:
    Cayman
    SKU:9000338 - 500 mg

    Available on backorder

  • Docosanoic acid methyl ester is an ester form of docosanoic acid (Item No. 9000338). It has been found in soybean, corn, sunflower, and canola oils, as well as beef fat, used in the production of biodiesel.{43913}  

     

    Brand:
    Cayman
    SKU:26866 - 1 g

    Available on backorder

  • Docosanoic acid methyl ester is an ester form of docosanoic acid (Item No. 9000338). It has been found in soybean, corn, sunflower, and canola oils, as well as beef fat, used in the production of biodiesel.{43913}  

     

    Brand:
    Cayman
    SKU:26866 - 5 g

    Available on backorder

  • Docosanoic acid-d4 is intended for use as an internal standard for the quantification of docosanoic acid (Item No. 9000338) by GC- or LC-MS. Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.{48322,48323} It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM).{31533} Docosanoic acid inhibits rat DNA polymerase β and human DNA polymerase λ activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM.{39264} Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet but not a high-cholesterol diet.{48324} Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.  

     

    Brand:
    Cayman
    SKU:28023 - 1 mg

    Available on backorder

  • Docosanoic acid-d4 is intended for use as an internal standard for the quantification of docosanoic acid (Item No. 9000338) by GC- or LC-MS. Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.{48322,48323} It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM).{31533} Docosanoic acid inhibits rat DNA polymerase β and human DNA polymerase λ activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM.{39264} Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet but not a high-cholesterol diet.{48324} Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.  

     

    Brand:
    Cayman
    SKU:28023 - 5 mg

    Available on backorder

  • Docosanoic acid-d4 is intended for use as an internal standard for the quantification of docosanoic acid (Item No. 9000338) by GC- or LC-MS. Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.{48322,48323} It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM).{31533} Docosanoic acid inhibits rat DNA polymerase β and human DNA polymerase λ activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM.{39264} Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet but not a high-cholesterol diet.{48324} Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.  

     

    Brand:
    Cayman
    SKU:28023 - 500 µg

    Available on backorder

  • Docosanoic acid-d43 is intended for use as an internal standard for the quantification of docosanoic acid (Item No. 9000338) by GC- or LC-MS. Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.{48322,48323} It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM).{31533} Docosanoic acid inhibits rat DNA polymerase β and human DNA polymerase λ activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM.{39264} Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat and high-cholesterol diet but not a high-cholesterol only diet.{48324} Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.  

     

    Brand:
    Cayman
    SKU:29075 - 1 mg

    Available on backorder

  • Docosanoic acid-d43 is intended for use as an internal standard for the quantification of docosanoic acid (Item No. 9000338) by GC- or LC-MS. Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.{48322,48323} It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM).{31533} Docosanoic acid inhibits rat DNA polymerase β and human DNA polymerase λ activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM.{39264} Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat and high-cholesterol diet but not a high-cholesterol only diet.{48324} Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.  

     

    Brand:
    Cayman
    SKU:29075 - 5 mg

    Available on backorder

  • Docosanol is an aliphatic alcohol that has broad-spectrum antiviral activity against viruses with a lipid envelope (ID50s = 3-12 nM for inhibition of replication).{41277} It inhibits herpes simplex virus type 1 (HSV-1) replication and protein synthesis in Vero cells.{41276} It also inhibits HSV-2 plaque formation and virus production in wild-type Vero cells and cells resistant to acyclovir (Item No. 14160). Docosanol acts by prohibiting the HSV envelope from fusing with the plasma membrane.{41277} Formulations containing docosanol have been used in the topical treatment of HSV-1.  

     

    Brand:
    Cayman
    SKU:23793 - 100 g

    Available on backorder

  • Docosanol is an aliphatic alcohol that has broad-spectrum antiviral activity against viruses with a lipid envelope (ID50s = 3-12 nM for inhibition of replication).{41277} It inhibits herpes simplex virus type 1 (HSV-1) replication and protein synthesis in Vero cells.{41276} It also inhibits HSV-2 plaque formation and virus production in wild-type Vero cells and cells resistant to acyclovir (Item No. 14160). Docosanol acts by prohibiting the HSV envelope from fusing with the plasma membrane.{41277} Formulations containing docosanol have been used in the topical treatment of HSV-1.  

     

    Brand:
    Cayman
    SKU:23793 - 250 g

    Available on backorder

  • Docosanol is an aliphatic alcohol that has broad-spectrum antiviral activity against viruses with a lipid envelope (ID50s = 3-12 nM for inhibition of replication).{41277} It inhibits herpes simplex virus type 1 (HSV-1) replication and protein synthesis in Vero cells.{41276} It also inhibits HSV-2 plaque formation and virus production in wild-type Vero cells and cells resistant to acyclovir (Item No. 14160). Docosanol acts by prohibiting the HSV envelope from fusing with the plasma membrane.{41277} Formulations containing docosanol have been used in the topical treatment of HSV-1.  

     

    Brand:
    Cayman
    SKU:23793 - 50 g

    Available on backorder

  • The endocannabinoids present a rich system of central cannabinoid (CB1), peripheral cannabinoid (CB2), and non-CB receptor-mediated pharmacology that has stimulated research in many fields including memory, weight loss and appetite, neurodegeneration, tumor surveillance, analgesia, and inflammation.{7912,7991} Docosanoyl ethanolamide is a saturated N-acylethanolamide. Non-cannabinoid receptor-mediated pharmacology of the saturated ethanolamides is still being elucidated.{10785} Other studies indicate they may have a role in the functioning of ion channels.{13759}  

     

    Brand:
    Cayman
    SKU:10005823 - 10 mg

    Available on backorder

  • The endocannabinoids present a rich system of central cannabinoid (CB1), peripheral cannabinoid (CB2), and non-CB receptor-mediated pharmacology that has stimulated research in many fields including memory, weight loss and appetite, neurodegeneration, tumor surveillance, analgesia, and inflammation.{7912,7991} Docosanoyl ethanolamide is a saturated N-acylethanolamide. Non-cannabinoid receptor-mediated pharmacology of the saturated ethanolamides is still being elucidated.{10785} Other studies indicate they may have a role in the functioning of ion channels.{13759}  

     

    Brand:
    Cayman
    SKU:10005823 - 100 mg

    Available on backorder

  • The endocannabinoids present a rich system of central cannabinoid (CB1), peripheral cannabinoid (CB2), and non-CB receptor-mediated pharmacology that has stimulated research in many fields including memory, weight loss and appetite, neurodegeneration, tumor surveillance, analgesia, and inflammation.{7912,7991} Docosanoyl ethanolamide is a saturated N-acylethanolamide. Non-cannabinoid receptor-mediated pharmacology of the saturated ethanolamides is still being elucidated.{10785} Other studies indicate they may have a role in the functioning of ion channels.{13759}  

     

    Brand:
    Cayman
    SKU:10005823 - 5 mg

    Available on backorder

  • The endocannabinoids present a rich system of central cannabinoid (CB1), peripheral cannabinoid (CB2), and non-CB receptor-mediated pharmacology that has stimulated research in many fields including memory, weight loss and appetite, neurodegeneration, tumor surveillance, analgesia, and inflammation.{7912,7991} Docosanoyl ethanolamide is a saturated N-acylethanolamide. Non-cannabinoid receptor-mediated pharmacology of the saturated ethanolamides is still being elucidated.{10785} Other studies indicate they may have a role in the functioning of ion channels.{13759}  

     

    Brand:
    Cayman
    SKU:10005823 - 50 mg

    Available on backorder

  • Docosapentaenoic acid is an ω-3 fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and increases on dietary supplementation.{1936}  

     

    Brand:
    Cayman
    SKU:90165 - 1 mg

    Available on backorder

  • Docosapentaenoic acid is an ω-3 fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and increases on dietary supplementation.{1936}  

     

    Brand:
    Cayman
    SKU:90165 - 10 mg

    Available on backorder

  • Docosapentaenoic acid is an ω-3 fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and increases on dietary supplementation.{1936}  

     

    Brand:
    Cayman
    SKU:90165 - 100 mg

    Available on backorder

  • Docosapentaenoic acid is an ω-3 fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and increases on dietary supplementation.{1936}  

     

    Brand:
    Cayman
    SKU:90165 - 25 mg

    Available on backorder

  • Docosapentaenoic acid ethyl ester is a derivative of DPA (Item No. 90165), an ω-3 fatty acid found in fish oils. Ethyl ester derivatives of fatty acids, including DPA, are often used in formulations designed as dietary supplements.{16505,33057,33058}  

     

    Brand:
    Cayman
    SKU:20669 -

    Available on backorder

  • Docosapentaenoic acid ethyl ester is a derivative of DPA (Item No. 90165), an ω-3 fatty acid found in fish oils. Ethyl ester derivatives of fatty acids, including DPA, are often used in formulations designed as dietary supplements.{16505,33057,33058}  

     

    Brand:
    Cayman
    SKU:20669 -

    Available on backorder

  • Docosapentaenoic acid ethyl ester is a derivative of DPA (Item No. 90165), an ω-3 fatty acid found in fish oils. Ethyl ester derivatives of fatty acids, including DPA, are often used in formulations designed as dietary supplements.{16505,33057,33058}  

     

    Brand:
    Cayman
    SKU:20669 -

    Available on backorder

  • Docosapentaenoic acid ethyl ester is a derivative of DPA (Item No. 90165), an ω-3 fatty acid found in fish oils. Ethyl ester derivatives of fatty acids, including DPA, are often used in formulations designed as dietary supplements.{16505,33057,33058}  

     

    Brand:
    Cayman
    SKU:20669 -

    Available on backorder

  • Docosapentaenoic acid methyl ester is an esterified form of docosapentaenoic acid (Item Nos. 90165 | 21907). It has been used as a reference standard in the quantification of fatty acids in microalgal and fish oils.{54169}  

     

    Brand:
    Cayman
    SKU:9001870 - 10 mg

    Available on backorder

  • Docosapentaenoic acid methyl ester is an esterified form of docosapentaenoic acid (Item Nos. 90165 | 21907). It has been used as a reference standard in the quantification of fatty acids in microalgal and fish oils.{54169}  

     

    Brand:
    Cayman
    SKU:9001870 - 25 mg

    Available on backorder

  • Docosapentaenoic acid methyl ester is an esterified form of docosapentaenoic acid (Item Nos. 90165 | 21907). It has been used as a reference standard in the quantification of fatty acids in microalgal and fish oils.{54169}  

     

    Brand:
    Cayman
    SKU:9001870 - 5 mg

    Available on backorder

  • Docosapentaenoic acid methyl ester is an esterified form of docosapentaenoic acid (Item Nos. 90165 | 21907). It has been used as a reference standard in the quantification of fatty acids in microalgal and fish oils.{54169}  

     

    Brand:
    Cayman
    SKU:9001870 - 50 mg

    Available on backorder

  • Docosapentaenoic Acid-d5 (DPA-d5) contains five deuterium atoms at the 21, 21, 22, 22 and 22 positions. It is intended for use as an internal standard for the quantification of DPA (Item No. 90165) by GC- or LC-MS. DPA is an ω-3 fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and increases on dietary supplementation.{1936}  

     

    Brand:
    Cayman
    SKU:20913 -

    Out of stock

  • Docosapentaenoic Acid-d5 (DPA-d5) contains five deuterium atoms at the 21, 21, 22, 22 and 22 positions. It is intended for use as an internal standard for the quantification of DPA (Item No. 90165) by GC- or LC-MS. DPA is an ω-3 fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and increases on dietary supplementation.{1936}  

     

    Brand:
    Cayman
    SKU:20913 -

    Out of stock

  • Docosapentaenoic Acid-d5 (DPA-d5) contains five deuterium atoms at the 21, 21, 22, 22 and 22 positions. It is intended for use as an internal standard for the quantification of DPA (Item No. 90165) by GC- or LC-MS. DPA is an ω-3 fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and increases on dietary supplementation.{1936}  

     

    Brand:
    Cayman
    SKU:20913 -

    Out of stock

  • Docosapentaenoic Acid-d5 (DPA-d5) contains five deuterium atoms at the 21, 21, 22, 22 and 22 positions. It is intended for use as an internal standard for the quantification of DPA (Item No. 90165) by GC- or LC-MS. DPA is an ω-3 fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and increases on dietary supplementation.{1936}  

     

    Brand:
    Cayman
    SKU:20913 -

    Out of stock

  • Docosapentaenoyl chloride is a derivative of the fatty acid docosapentaenoic acid (DPA; Item No. 90165 | 21907), an ω-3 fatty acid found in fish oils, that is more reactive than the free fatty acid.  

     

    Brand:
    Cayman
    SKU:22720 -

    Out of stock

  • Docosapentaenoyl chloride is a derivative of the fatty acid docosapentaenoic acid (DPA; Item No. 90165 | 21907), an ω-3 fatty acid found in fish oils, that is more reactive than the free fatty acid.  

     

    Brand:
    Cayman
    SKU:22720 -

    Out of stock

  • Docosapentaenoyl chloride is a derivative of the fatty acid docosapentaenoic acid (DPA; Item No. 90165 | 21907), an ω-3 fatty acid found in fish oils, that is more reactive than the free fatty acid.  

     

    Brand:
    Cayman
    SKU:22720 -

    Out of stock

  • Docosapentaenoyl chloride is a derivative of the fatty acid docosapentaenoic acid (DPA; Item No. 90165 | 21907), an ω-3 fatty acid found in fish oils, that is more reactive than the free fatty acid.  

     

    Brand:
    Cayman
    SKU:22720 -

    Out of stock

  • Docosatetraenoyl ethanolamide (DEA) is an endocannabinoid containing docosatetraenoic acid in place of the arachidonate moiety of AEA. DEA acts on CB1 receptors with potency and efficacy similar to that of AEA.{2713} However, its specific role and relative importance as a cannabinergic neurotransmitter have not been elucidated.{1172}  

     

    Brand:
    Cayman
    SKU:90385 - 10 mg

    Available on backorder

  • Docosatetraenoyl ethanolamide (DEA) is an endocannabinoid containing docosatetraenoic acid in place of the arachidonate moiety of AEA. DEA acts on CB1 receptors with potency and efficacy similar to that of AEA.{2713} However, its specific role and relative importance as a cannabinergic neurotransmitter have not been elucidated.{1172}  

     

    Brand:
    Cayman
    SKU:90385 - 25 mg

    Available on backorder

  • Docosatetraenoyl ethanolamide (DEA) is an endocannabinoid containing docosatetraenoic acid in place of the arachidonate moiety of AEA. DEA acts on CB1 receptors with potency and efficacy similar to that of AEA.{2713} However, its specific role and relative importance as a cannabinergic neurotransmitter have not been elucidated.{1172}  

     

    Brand:
    Cayman
    SKU:90385 - 5 mg

    Available on backorder

  • Docosatetraenoyl ethanolamide (DEA) is an endocannabinoid containing docosatetraenoic acid in place of the arachidonate moiety of AEA. DEA acts on CB1 receptors with potency and efficacy similar to that of AEA.{2713} However, its specific role and relative importance as a cannabinergic neurotransmitter have not been elucidated.{1172}  

     

    Brand:
    Cayman
    SKU:90385 - 50 mg

    Available on backorder

  • Docosatrienoic acid is a rare ω-3 fatty acid not readily detected in normal phospholipid PUFA pools. It is a polyunsaturated version of the fatty acid docosanoic acid (Item No. 9000338). Docosatrienoic acid inhibits [3H]-LTB4 binding to pig neutrophils at a concentration of 5 µM.{2361} It also dose-dependently inhibits the activity of mammalian DNA polymerases and human topoisomerases I and II, potentially by binding directly to the hydrophobic region of the enzymes.{39264} The cis configuration of the double bonds is important for this activity, and the carboxyl group is required as the methyl ester version has no activity at these enzymes.  

     

    Brand:
    Cayman
    SKU:90170 - 100 mg

    Available on backorder

  • Docosatrienoic acid is a rare ω-3 fatty acid not readily detected in normal phospholipid PUFA pools. It is a polyunsaturated version of the fatty acid docosanoic acid (Item No. 9000338). Docosatrienoic acid inhibits [3H]-LTB4 binding to pig neutrophils at a concentration of 5 µM.{2361} It also dose-dependently inhibits the activity of mammalian DNA polymerases and human topoisomerases I and II, potentially by binding directly to the hydrophobic region of the enzymes.{39264} The cis configuration of the double bonds is important for this activity, and the carboxyl group is required as the methyl ester version has no activity at these enzymes.  

     

    Brand:
    Cayman
    SKU:90170 - 25 mg

    Available on backorder

  • Docosatrienoic acid is a rare ω-3 fatty acid not readily detected in normal phospholipid PUFA pools. It is a polyunsaturated version of the fatty acid docosanoic acid (Item No. 9000338). Docosatrienoic acid inhibits [3H]-LTB4 binding to pig neutrophils at a concentration of 5 µM.{2361} It also dose-dependently inhibits the activity of mammalian DNA polymerases and human topoisomerases I and II, potentially by binding directly to the hydrophobic region of the enzymes.{39264} The cis configuration of the double bonds is important for this activity, and the carboxyl group is required as the methyl ester version has no activity at these enzymes.  

     

    Brand:
    Cayman
    SKU:90170 - 50 mg

    Available on backorder

  • Docosatrienoic acid methyl ester is an ester version of docosatrienoic acid (Item No. 90170), a rare ω-3 fatty acid not readily detected in normal phospholipid polyunsaturated fatty acid pools that inhibits [3H]-LTB4 binding to pig neutrophils at a concentration of 5 µM.{2361} Docosatrienoic acid methyl ester is more lipid soluble than the free acid and may be more desirable than the free acid in certain formulations.  

     

    Brand:
    Cayman
    SKU:20567 -

    Available on backorder

  • Docosatrienoic acid methyl ester is an ester version of docosatrienoic acid (Item No. 90170), a rare ω-3 fatty acid not readily detected in normal phospholipid polyunsaturated fatty acid pools that inhibits [3H]-LTB4 binding to pig neutrophils at a concentration of 5 µM.{2361} Docosatrienoic acid methyl ester is more lipid soluble than the free acid and may be more desirable than the free acid in certain formulations.  

     

    Brand:
    Cayman
    SKU:20567 -

    Available on backorder

  • Docosatrienoic acid methyl ester is an ester version of docosatrienoic acid (Item No. 90170), a rare ω-3 fatty acid not readily detected in normal phospholipid polyunsaturated fatty acid pools that inhibits [3H]-LTB4 binding to pig neutrophils at a concentration of 5 µM.{2361} Docosatrienoic acid methyl ester is more lipid soluble than the free acid and may be more desirable than the free acid in certain formulations.  

     

    Brand:
    Cayman
    SKU:20567 -

    Available on backorder

  • Docosatrienoic acid methyl ester is an ester version of docosatrienoic acid (Item No. 90170), a rare ω-3 fatty acid not readily detected in normal phospholipid polyunsaturated fatty acid pools that inhibits [3H]-LTB4 binding to pig neutrophils at a concentration of 5 µM.{2361} Docosatrienoic acid methyl ester is more lipid soluble than the free acid and may be more desirable than the free acid in certain formulations.  

     

    Brand:
    Cayman
    SKU:20567 -

    Available on backorder

  • Docusate is a surfactant.{61028} It forms reverse micelles in oils and increases the solubility of water in oil by forming microemulsions. Docusate has been used in protein extraction, cryo-enzymology, the preparation of ceramic nanoparticles and gelatin-based nanopallets, and as a charge control agent in particle migration imaging.  

     

    Brand:
    Cayman
    SKU:30692 - 100 g

    Available on backorder

  • Docusate is a surfactant.{61028} It forms reverse micelles in oils and increases the solubility of water in oil by forming microemulsions. Docusate has been used in protein extraction, cryo-enzymology, the preparation of ceramic nanoparticles and gelatin-based nanopallets, and as a charge control agent in particle migration imaging.  

     

    Brand:
    Cayman
    SKU:30692 - 250 g

    Available on backorder

  • Dodecanoyl D-sucrose is a nonionic surfactant.{48956} It is active against B. cereus, B. subtilis, S. aureus, E. coli, and S. typhimurium in a disc diffusion assay when used at a concentration of 255 mM. Transcutaneous immunization of mice with dodecanoyl D-sucrose-coated ovalbumin increases serum IgG levels by 5-fold compared to immunization with uncoated ovalbumin.{48957} Topical administration of a dodecanoyl D-sucrose hydrogel (15% v/v) containing estradiol increases serum estradiol levels in rabbits compared to an ethanol-containing hydrogel.{48958} Dodecanoyl D-sucrose has been used to prepare stable foams in aqueous solutions, as well as oil-in-water emulsions.{48959}  

     

    Brand:
    Cayman
    SKU:29982 - 1 g

    Available on backorder

  • Dodecanoyl D-sucrose is a nonionic surfactant.{48956} It is active against B. cereus, B. subtilis, S. aureus, E. coli, and S. typhimurium in a disc diffusion assay when used at a concentration of 255 mM. Transcutaneous immunization of mice with dodecanoyl D-sucrose-coated ovalbumin increases serum IgG levels by 5-fold compared to immunization with uncoated ovalbumin.{48957} Topical administration of a dodecanoyl D-sucrose hydrogel (15% v/v) containing estradiol increases serum estradiol levels in rabbits compared to an ethanol-containing hydrogel.{48958} Dodecanoyl D-sucrose has been used to prepare stable foams in aqueous solutions, as well as oil-in-water emulsions.{48959}  

     

    Brand:
    Cayman
    SKU:29982 - 250 mg

    Available on backorder

  • Dodecanoyl D-sucrose is a nonionic surfactant.{48956} It is active against B. cereus, B. subtilis, S. aureus, E. coli, and S. typhimurium in a disc diffusion assay when used at a concentration of 255 mM. Transcutaneous immunization of mice with dodecanoyl D-sucrose-coated ovalbumin increases serum IgG levels by 5-fold compared to immunization with uncoated ovalbumin.{48957} Topical administration of a dodecanoyl D-sucrose hydrogel (15% v/v) containing estradiol increases serum estradiol levels in rabbits compared to an ethanol-containing hydrogel.{48958} Dodecanoyl D-sucrose has been used to prepare stable foams in aqueous solutions, as well as oil-in-water emulsions.{48959}  

     

    Brand:
    Cayman
    SKU:29982 - 5 g

    Available on backorder

  • Dodecanoyl D-sucrose is a nonionic surfactant.{48956} It is active against B. cereus, B. subtilis, S. aureus, E. coli, and S. typhimurium in a disc diffusion assay when used at a concentration of 255 mM. Transcutaneous immunization of mice with dodecanoyl D-sucrose-coated ovalbumin increases serum IgG levels by 5-fold compared to immunization with uncoated ovalbumin.{48957} Topical administration of a dodecanoyl D-sucrose hydrogel (15% v/v) containing estradiol increases serum estradiol levels in rabbits compared to an ethanol-containing hydrogel.{48958} Dodecanoyl D-sucrose has been used to prepare stable foams in aqueous solutions, as well as oil-in-water emulsions.{48959}  

     

    Brand:
    Cayman
    SKU:29982 - 500 mg

    Available on backorder

  • Dodecyl gallate is a derivative of the antioxidant gallic acid (Item No. 11846) that has diverse biological activities, including antioxidant, antiproliferative, and antibacterial properties.{61105,61106,61107} It inhibits proliferation of a variety of cancer cells, including WEHI-231 mouse B cell lymphoma, Daudi human lymphoma, and HT-29 human colon cancer cells (IC50s = 0.8, 1.4, and 17.0 µM, respectively).{61105} It induces apoptosis of WEHI-231 cells but not L-929 mouse fibroblasts. Dodecyl gallate decreases peroxidation of ox brain phospholipid liposomes by 71 and 76% when used at concentrations of 12 and 50 µM, respectively, and scavenges trichloromethyl peroxyl radicals at 0.05% w/v.{61106} It is active against a variety of Gram-positive bacteria, including B. subtilis (MIC = 25 µg/ml), as well as M. luteus, S. aureus, and methicillin-resistant S. aureus (MRSA; MICs = 12.5 µg/ml for all), and acts by inhibiting the bacterial membrane respiratory chain.{61107}  

     

    Brand:
    Cayman
    SKU:31401 - 100 g

    Available on backorder

  • Dodecyl gallate is a derivative of the antioxidant gallic acid (Item No. 11846) that has diverse biological activities, including antioxidant, antiproliferative, and antibacterial properties.{61105,61106,61107} It inhibits proliferation of a variety of cancer cells, including WEHI-231 mouse B cell lymphoma, Daudi human lymphoma, and HT-29 human colon cancer cells (IC50s = 0.8, 1.4, and 17.0 µM, respectively).{61105} It induces apoptosis of WEHI-231 cells but not L-929 mouse fibroblasts. Dodecyl gallate decreases peroxidation of ox brain phospholipid liposomes by 71 and 76% when used at concentrations of 12 and 50 µM, respectively, and scavenges trichloromethyl peroxyl radicals at 0.05% w/v.{61106} It is active against a variety of Gram-positive bacteria, including B. subtilis (MIC = 25 µg/ml), as well as M. luteus, S. aureus, and methicillin-resistant S. aureus (MRSA; MICs = 12.5 µg/ml for all), and acts by inhibiting the bacterial membrane respiratory chain.{61107}  

     

    Brand:
    Cayman
    SKU:31401 - 25 g

    Available on backorder

  • Dodecyl gallate is a derivative of the antioxidant gallic acid (Item No. 11846) that has diverse biological activities, including antioxidant, antiproliferative, and antibacterial properties.{61105,61106,61107} It inhibits proliferation of a variety of cancer cells, including WEHI-231 mouse B cell lymphoma, Daudi human lymphoma, and HT-29 human colon cancer cells (IC50s = 0.8, 1.4, and 17.0 µM, respectively).{61105} It induces apoptosis of WEHI-231 cells but not L-929 mouse fibroblasts. Dodecyl gallate decreases peroxidation of ox brain phospholipid liposomes by 71 and 76% when used at concentrations of 12 and 50 µM, respectively, and scavenges trichloromethyl peroxyl radicals at 0.05% w/v.{61106} It is active against a variety of Gram-positive bacteria, including B. subtilis (MIC = 25 µg/ml), as well as M. luteus, S. aureus, and methicillin-resistant S. aureus (MRSA; MICs = 12.5 µg/ml for all), and acts by inhibiting the bacterial membrane respiratory chain.{61107}  

     

    Brand:
    Cayman
    SKU:31401 - 250 g

    Available on backorder

  • Dodecyl gallate is a derivative of the antioxidant gallic acid (Item No. 11846) that has diverse biological activities, including antioxidant, antiproliferative, and antibacterial properties.{61105,61106,61107} It inhibits proliferation of a variety of cancer cells, including WEHI-231 mouse B cell lymphoma, Daudi human lymphoma, and HT-29 human colon cancer cells (IC50s = 0.8, 1.4, and 17.0 µM, respectively).{61105} It induces apoptosis of WEHI-231 cells but not L-929 mouse fibroblasts. Dodecyl gallate decreases peroxidation of ox brain phospholipid liposomes by 71 and 76% when used at concentrations of 12 and 50 µM, respectively, and scavenges trichloromethyl peroxyl radicals at 0.05% w/v.{61106} It is active against a variety of Gram-positive bacteria, including B. subtilis (MIC = 25 µg/ml), as well as M. luteus, S. aureus, and methicillin-resistant S. aureus (MRSA; MICs = 12.5 µg/ml for all), and acts by inhibiting the bacterial membrane respiratory chain.{61107}  

     

    Brand:
    Cayman
    SKU:31401 - 50 g

    Available on backorder

  • Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR.{36909} It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane.{36910} Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) β-strand (PrP (110-136)).{36911} Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM.  

     

    Brand:
    Cayman
    SKU:25629 - 1 g

    Available on backorder

  • Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR.{36909} It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane.{36910} Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) β-strand (PrP (110-136)).{36911} Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM.  

     

    Brand:
    Cayman
    SKU:25629 - 250 mg

    Available on backorder

  • Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR.{36909} It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane.{36910} Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) β-strand (PrP (110-136)).{36911} Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM.  

     

    Brand:
    Cayman
    SKU:25629 - 500 mg

    Available on backorder

  • Dodecylphosphocholine-d38 is intended for use as an internal standard for the quantification of dodecylphosphocholine (Item No. 25629) by GC- or LC-MS. Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR.{36909} It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane.{36910} Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) β-strand (PrP (110-136)).{36911} Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM.  

     

    Brand:
    Cayman
    SKU:25996 - 100 mg

    Available on backorder

  • Dodecylphosphocholine-d38 is intended for use as an internal standard for the quantification of dodecylphosphocholine (Item No. 25629) by GC- or LC-MS. Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR.{36909} It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane.{36910} Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) β-strand (PrP (110-136)).{36911} Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM.  

     

    Brand:
    Cayman
    SKU:25996 - 25 mg

    Available on backorder

  • Dodecylphosphocholine-d38 is intended for use as an internal standard for the quantification of dodecylphosphocholine (Item No. 25629) by GC- or LC-MS. Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR.{36909} It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane.{36910} Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) β-strand (PrP (110-136)).{36911} Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM.  

     

    Brand:
    Cayman
    SKU:25996 - 250 mg

    Available on backorder

  • Dodecylphosphocholine-d38 is intended for use as an internal standard for the quantification of dodecylphosphocholine (Item No. 25629) by GC- or LC-MS. Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR.{36909} It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane.{36910} Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) β-strand (PrP (110-136)).{36911} Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM.  

     

    Brand:
    Cayman
    SKU:25996 - 50 mg

    Available on backorder

  • DOET is a potent, long-acting psychoactive drug of the phenethylamine and amphetamine chemical classes that, similar to other substituted amphetamines, likely acts as a serotonin 5-HT2 receptor partial agonist.{20771,21076} This compound is classified as a Schedule I substance in the United States, and is intended only for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:-
  • Dofequidar is a quinoline derivative and inhibitor of multidrug resistance.{53975,53976} It inhibits P-glycoprotein in a photolabeling assay when used at a concentration of 100 μM.{53975} Dofequidar (10 μM) increases intracellular accumulation of [3H]-vincristine in HL-60R cells endogenously expressing the gene encoding multidrug resistance-associated protein (MRP).{53976} It restores susceptibility to vincristine- or doxorubicin-induced cytotoxicity in vincristine-resistant P388, vincristine-resistant K562, and doxorubicin-resistant K562 cells in a concentration-dependent manner.{53975} Dofequidar (80 mg/kg twice per day) increases survival in a vincristine-resistant P388 murine leukemia model compared with untreated controls when administered in combination with vincristine (Item No. 11764).  

     

    Brand:
    Cayman
    SKU:30925 - 1 mg

    Available on backorder

  • Dofequidar is a quinoline derivative and inhibitor of multidrug resistance.{53975,53976} It inhibits P-glycoprotein in a photolabeling assay when used at a concentration of 100 μM.{53975} Dofequidar (10 μM) increases intracellular accumulation of [3H]-vincristine in HL-60R cells endogenously expressing the gene encoding multidrug resistance-associated protein (MRP).{53976} It restores susceptibility to vincristine- or doxorubicin-induced cytotoxicity in vincristine-resistant P388, vincristine-resistant K562, and doxorubicin-resistant K562 cells in a concentration-dependent manner.{53975} Dofequidar (80 mg/kg twice per day) increases survival in a vincristine-resistant P388 murine leukemia model compared with untreated controls when administered in combination with vincristine (Item No. 11764).  

     

    Brand:
    Cayman
    SKU:30925 - 10 mg

    Available on backorder

  • Dofequidar is a quinoline derivative and inhibitor of multidrug resistance.{53975,53976} It inhibits P-glycoprotein in a photolabeling assay when used at a concentration of 100 μM.{53975} Dofequidar (10 μM) increases intracellular accumulation of [3H]-vincristine in HL-60R cells endogenously expressing the gene encoding multidrug resistance-associated protein (MRP).{53976} It restores susceptibility to vincristine- or doxorubicin-induced cytotoxicity in vincristine-resistant P388, vincristine-resistant K562, and doxorubicin-resistant K562 cells in a concentration-dependent manner.{53975} Dofequidar (80 mg/kg twice per day) increases survival in a vincristine-resistant P388 murine leukemia model compared with untreated controls when administered in combination with vincristine (Item No. 11764).  

     

    Brand:
    Cayman
    SKU:30925 - 5 mg

    Available on backorder

  • Dofetilide is a class III antiarrhythmic agent that prolongs cardiac action potential duration by selectively inhibiting the rapidly activating inward rectifying component of net delayed rectifier K+ current (IC50 = 31.5 nM in guinea pig cardiomyocytes).{24130} However, at 1 μM, dofetilide has pro-arrhythmic activity, inducing early afterdepolarizations (prolonged repolarization) in cell models and Torsade de Pointes in a rabbit screen for proarrhythmic properties when administered at a dose of 10 mg/kg.{24131} Formulations containing dofetilide have been used in the treatment of highly symptomatic atrial fibrillation and the conversion of flutter to normal sinus rhythm.{24132}  

     

    Brand:
    Cayman
    SKU:-
  • Dofetilide is a class III antiarrhythmic agent that prolongs cardiac action potential duration by selectively inhibiting the rapidly activating inward rectifying component of net delayed rectifier K+ current (IC50 = 31.5 nM in guinea pig cardiomyocytes).{24130} However, at 1 μM, dofetilide has pro-arrhythmic activity, inducing early afterdepolarizations (prolonged repolarization) in cell models and Torsade de Pointes in a rabbit screen for proarrhythmic properties when administered at a dose of 10 mg/kg.{24131} Formulations containing dofetilide have been used in the treatment of highly symptomatic atrial fibrillation and the conversion of flutter to normal sinus rhythm.{24132}  

     

    Brand:
    Cayman
    SKU:-
  • Dofetilide is a class III antiarrhythmic agent that prolongs cardiac action potential duration by selectively inhibiting the rapidly activating inward rectifying component of net delayed rectifier K+ current (IC50 = 31.5 nM in guinea pig cardiomyocytes).{24130} However, at 1 μM, dofetilide has pro-arrhythmic activity, inducing early afterdepolarizations (prolonged repolarization) in cell models and Torsade de Pointes in a rabbit screen for proarrhythmic properties when administered at a dose of 10 mg/kg.{24131} Formulations containing dofetilide have been used in the treatment of highly symptomatic atrial fibrillation and the conversion of flutter to normal sinus rhythm.{24132}  

     

    Brand:
    Cayman
    SKU:-