Cayman
Showing 18751–18900 of 45550 results
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DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer.{22083,22087,22086} Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG), 8-hydroxy-2’-deoxyguanosine (8-OHdG), and 8-hydroxyguanine. Some commercial vendors offer immunoassays that detect only 8-OHdG. Cayman’s DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit is a competitive assay that can be used to measure 8-OHdG, 8-OHG, and 8-hydroxyguanine. Since the antibody used in the assay recognizes damaged nucleic acid species other than 8-OHdG, the value obtained with our assay will be higher than that obtained by competitor ELISAs or by LC/MS analysis that measure a single species. As such, caution is recommended when comparing results obtained from this kit to those obtained by other methods.
Brand:CaymanSKU:589320 - 480 solid wellsAvailable on backorder
DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer.{22083,22087,22086} Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG), 8-hydroxy-2’-deoxyguanosine (8-OHdG), and 8-hydroxyguanine. Some commercial vendors offer immunoassays that detect only 8-OHdG. Cayman’s DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit is a competitive assay that can be used to measure 8-OHdG, 8-OHG, and 8-hydroxyguanine. Since the antibody used in the assay recognizes damaged nucleic acid species other than 8-OHdG, the value obtained with our assay will be higher than that obtained by competitor ELISAs or by LC/MS analysis that measure a single species. As such, caution is recommended when comparing results obtained from this kit to those obtained by other methods.
Brand:CaymanSKU:589320 - 480 strip wellsAvailable on backorder
DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer.{22083,22087,22086} Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG), 8-hydroxy-2’-deoxyguanosine (8-OHdG), and 8-hydroxyguanine. Some commercial vendors offer immunoassays that detect only 8-OHdG. Cayman’s DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit is a competitive assay that can be used to measure 8-OHdG, 8-OHG, and 8-hydroxyguanine. Since the antibody used in the assay recognizes damaged nucleic acid species other than 8-OHdG, the value obtained with our assay will be higher than that obtained by competitor ELISAs or by LC/MS analysis that measure a single species. As such, caution is recommended when comparing results obtained from this kit to those obtained by other methods.
Brand:CaymanSKU:589320 - 96 solid wellsAvailable on backorder
DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer.{22083,22087,22086} Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG), 8-hydroxy-2’-deoxyguanosine (8-OHdG), and 8-hydroxyguanine. Some commercial vendors offer immunoassays that detect only 8-OHdG. Cayman’s DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit is a competitive assay that can be used to measure 8-OHdG, 8-OHG, and 8-hydroxyguanine. Since the antibody used in the assay recognizes damaged nucleic acid species other than 8-OHdG, the value obtained with our assay will be higher than that obtained by competitor ELISAs or by LC/MS analysis that measure a single species. As such, caution is recommended when comparing results obtained from this kit to those obtained by other methods.
Brand:CaymanSKU:589320 - 96 strip wellsAvailable on backorder
Brand:CaymanSKU:10012603 - 1 eaAvailable on backorder
DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM).{40283} It inhibits electron flow from water to NADP or methylviologen by 50 and 100% when used at concentrations of 0.5 or 5 µM, respectively.{40281,40282}
Brand:CaymanSKU:9003061 - 1 mgAvailable on backorder
DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM).{40283} It inhibits electron flow from water to NADP or methylviologen by 50 and 100% when used at concentrations of 0.5 or 5 µM, respectively.{40281,40282}
Brand:CaymanSKU:9003061 - 10 mgAvailable on backorder
DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM).{40283} It inhibits electron flow from water to NADP or methylviologen by 50 and 100% when used at concentrations of 0.5 or 5 µM, respectively.{40281,40282}
Brand:CaymanSKU:9003061 - 25 mgAvailable on backorder
DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM).{40283} It inhibits electron flow from water to NADP or methylviologen by 50 and 100% when used at concentrations of 0.5 or 5 µM, respectively.{40281,40282}
Brand:CaymanSKU:9003061 - 5 mgAvailable on backorder
Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9.{38801} Upon cleavage by MMP-1 or MMP-9, N-methylanthranilic acid (Nma) is unquenched and its fluorescence can be used to quantify MMP activity. Nma displays excitation/emission spectra of 340/440 nm, respectively.
Brand:CaymanSKU:24709 - 1 mgAvailable on backorder
Dnp-PYAYWMR is a fluorgenic heptapeptide substrate for matrix metalloproteinase-8 (MMP-8).{40722} MMP-8 activity can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis that removes the N-terminal dinitrophenol (DNP) group.
Brand:CaymanSKU:24538 - 1 mgAvailable on backorder
DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively versus IC50 = 40 μM for NMDA receptors).{23070,23071,23072} This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-term potentiation in the hippocampus.{23069}
Brand:CaymanSKU:- DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively versus IC50 = 40 μM for NMDA receptors).{23070,23071,23072} This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-term potentiation in the hippocampus.{23069}
Brand:CaymanSKU:- DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively versus IC50 = 40 μM for NMDA receptors).{23070,23071,23072} This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-term potentiation in the hippocampus.{23069}
Brand:CaymanSKU:- DNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively versus IC50 = 40 μM for NMDA receptors).{23070,23071,23072} This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-term potentiation in the hippocampus.{23069}
Brand:CaymanSKU:-
DO264 is an inhibitor of α/β-hydrolase domain-containing protein 12 (ABHD12; IC50 = 11 nM).{45704} It inhibits ABHD12-dependent hydrolysis of lysophosphatidylserine (lyso-PS) in mouse brain membrane lysates (IC50 = 2.8 nM) and human THP-1 cells.{45705} DO264 increases levels of chemokine (C-C motif) ligand 3 (CCL3), CCL4, TNF-α, and IL-1β in M1-polarized THP-1 macrophages. It potentiates ferroptotic cell death induced by the glutathione peroxidase 4 (GPX4) inhibitor RSL3 in HT1080 fibrosarcoma and SU-DHL-5 B cell lymphoma cells when used at a concentration of 1 μM.{45704,49606} In vivo, DO264 (30 mg/kg per day for four weeks) increases levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PS, 1-arachidonoyl-2-hydroxy-sn-glycero-3-PS, 1-docosanoyl-2-hydroxy-sn-glycero-3-PS, 1-stearoyl-2-arachidonoyl-sn-glycero-3-PS, and 1-oleoyl-2-arachidonoyl-sn-glycero-3-PS in mouse brain.{45705} It increases levels of CCL2, CCL3, and CCL5 in bronchoalveolar lavage fluid (BALF) and decreases survival in a mouse model of infection with lymphocytic choriomeningitis virus (LCMV) clone 13 when administered at a dose of 30 mg/kg.
Brand:CaymanSKU:29402 - 1 mgAvailable on backorder
DO264 is an inhibitor of α/β-hydrolase domain-containing protein 12 (ABHD12; IC50 = 11 nM).{45704} It inhibits ABHD12-dependent hydrolysis of lysophosphatidylserine (lyso-PS) in mouse brain membrane lysates (IC50 = 2.8 nM) and human THP-1 cells.{45705} DO264 increases levels of chemokine (C-C motif) ligand 3 (CCL3), CCL4, TNF-α, and IL-1β in M1-polarized THP-1 macrophages. It potentiates ferroptotic cell death induced by the glutathione peroxidase 4 (GPX4) inhibitor RSL3 in HT1080 fibrosarcoma and SU-DHL-5 B cell lymphoma cells when used at a concentration of 1 μM.{45704,49606} In vivo, DO264 (30 mg/kg per day for four weeks) increases levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PS, 1-arachidonoyl-2-hydroxy-sn-glycero-3-PS, 1-docosanoyl-2-hydroxy-sn-glycero-3-PS, 1-stearoyl-2-arachidonoyl-sn-glycero-3-PS, and 1-oleoyl-2-arachidonoyl-sn-glycero-3-PS in mouse brain.{45705} It increases levels of CCL2, CCL3, and CCL5 in bronchoalveolar lavage fluid (BALF) and decreases survival in a mouse model of infection with lymphocytic choriomeningitis virus (LCMV) clone 13 when administered at a dose of 30 mg/kg.
Brand:CaymanSKU:29402 - 10 mgAvailable on backorder
DO264 is an inhibitor of α/β-hydrolase domain-containing protein 12 (ABHD12; IC50 = 11 nM).{45704} It inhibits ABHD12-dependent hydrolysis of lysophosphatidylserine (lyso-PS) in mouse brain membrane lysates (IC50 = 2.8 nM) and human THP-1 cells.{45705} DO264 increases levels of chemokine (C-C motif) ligand 3 (CCL3), CCL4, TNF-α, and IL-1β in M1-polarized THP-1 macrophages. It potentiates ferroptotic cell death induced by the glutathione peroxidase 4 (GPX4) inhibitor RSL3 in HT1080 fibrosarcoma and SU-DHL-5 B cell lymphoma cells when used at a concentration of 1 μM.{45704,49606} In vivo, DO264 (30 mg/kg per day for four weeks) increases levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PS, 1-arachidonoyl-2-hydroxy-sn-glycero-3-PS, 1-docosanoyl-2-hydroxy-sn-glycero-3-PS, 1-stearoyl-2-arachidonoyl-sn-glycero-3-PS, and 1-oleoyl-2-arachidonoyl-sn-glycero-3-PS in mouse brain.{45705} It increases levels of CCL2, CCL3, and CCL5 in bronchoalveolar lavage fluid (BALF) and decreases survival in a mouse model of infection with lymphocytic choriomeningitis virus (LCMV) clone 13 when administered at a dose of 30 mg/kg.
Brand:CaymanSKU:29402 - 5 mgAvailable on backorder
DOAM (Item No. 17656) is an analytical reference standard that is structurally categorized as an amphetamine. Experiments with isolated rat thoracic aorta suggested that this compound may act as an antagonist of the 5-HT2 receptor.{30477} This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
DOAM (Item No. 17656) is an analytical reference standard that is structurally categorized as an amphetamine. Experiments with isolated rat thoracic aorta suggested that this compound may act as an antagonist of the 5-HT2 receptor.{30477} This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
DOAM (Item No. 17656) is an analytical reference standard that is structurally categorized as an amphetamine. Experiments with isolated rat thoracic aorta suggested that this compound may act as an antagonist of the 5-HT2 receptor.{30477} This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
DOBU (Item No. 17655) is an analytical reference standard that is structurally categorized as an amphetamine. Experiments with isolated rat thoracic aorta suggested that this compound may act as an antagonist of the 5-HT2 receptor.{30477} This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
DOBU (Item No. 17655) is an analytical reference standard that is structurally categorized as an amphetamine. Experiments with isolated rat thoracic aorta suggested that this compound may act as an antagonist of the 5-HT2 receptor.{30477} This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
DOBU (Item No. 17655) is an analytical reference standard that is structurally categorized as an amphetamine. Experiments with isolated rat thoracic aorta suggested that this compound may act as an antagonist of the 5-HT2 receptor.{30477} This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
Dobutamine is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects in vivo.{25418,25421,25419} It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions.{25418,25421} As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects.{25418} Dobutamine is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1 μM.{25420}
Brand:CaymanSKU:- Dobutamine is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects in vivo.{25418,25421,25419} It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions.{25418,25421} As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects.{25418} Dobutamine is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1 μM.{25420}
Brand:CaymanSKU:- Dobutamine is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects in vivo.{25418,25421,25419} It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions.{25418,25421} As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects.{25418} Dobutamine is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1 μM.{25420}
Brand:CaymanSKU:- Dobutamine is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects in vivo.{25418,25421,25419} It has its strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions.{25418,25421} As a result, it strongly increases cardiac contractility with modest chronotropic, arrhythmogenic, and vascular side effects.{25418} Dobutamine is also a polyphenolic antioxidant and can inhibit all human carbonic anhydrase isoforms with Ki values near 1 μM.{25420}
Brand:CaymanSKU:-
Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM).{20977} It has proven more effective than taxol in preventing the proliferation of cancer cells.{20977,20979} Docetaxel has applications in breast cancer and hormone-refractory prostate cancer.{20980,20978} This product is intended for research applications.
Brand:CaymanSKU:11637 - 10 mgAvailable on backorder
Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM).{20977} It has proven more effective than taxol in preventing the proliferation of cancer cells.{20977,20979} Docetaxel has applications in breast cancer and hormone-refractory prostate cancer.{20980,20978} This product is intended for research applications.
Brand:CaymanSKU:11637 - 250 mgAvailable on backorder
Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM).{20977} It has proven more effective than taxol in preventing the proliferation of cancer cells.{20977,20979} Docetaxel has applications in breast cancer and hormone-refractory prostate cancer.{20980,20978} This product is intended for research applications.
Brand:CaymanSKU:11637 - 5 mgAvailable on backorder
Docetaxel is a semisynthetic analog of taxol that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM).{20977} It has proven more effective than taxol in preventing the proliferation of cancer cells.{20977,20979} Docetaxel has applications in breast cancer and hormone-refractory prostate cancer.{20980,20978} This product is intended for research applications.
Brand:CaymanSKU:11637 - 50 mgAvailable on backorder
Docetaxel-d9 is intended for use as an internal standard for the quantification of docetaxel (Item No. 11637) by GC- or LC-MS. Docetaxel is a semisynthetic analog of paclitaxel (Item No. 10461) that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM).{20977} It has proven more effective than taxol in preventing the proliferation of cancer cells.{20977,20979} Docetaxel has potential applications in breast cancer and hormone-refractory prostate cancer.{20980,20978}
Brand:CaymanSKU:22094 -Out of stock
Docetaxel-d9 is intended for use as an internal standard for the quantification of docetaxel (Item No. 11637) by GC- or LC-MS. Docetaxel is a semisynthetic analog of paclitaxel (Item No. 10461) that inhibits microtubule disassembly (IC50 = 0.2 μM) and inhibits cell replication (IC50 = 0.13 μM).{20977} It has proven more effective than taxol in preventing the proliferation of cancer cells.{20977,20979} Docetaxel has potential applications in breast cancer and hormone-refractory prostate cancer.{20980,20978}
Brand:CaymanSKU:22094 -Out of stock
Docosadienoic acid methyl ester is an esterified version of 13Z,16Z-docosadienoic acid (Item No. 20749), which is a natural ω-6 polyunsaturated fatty acid (PUFA). Docosadienoic acid is an agonist of free fatty acid receptor 4 (FFAR4, also known as GPR120) and strongly inhibits the secretion of ghrelin by isolated mouse gastric cells.{32737}
Brand:CaymanSKU:20602 -Available on backorder
Docosadienoic acid methyl ester is an esterified version of 13Z,16Z-docosadienoic acid (Item No. 20749), which is a natural ω-6 polyunsaturated fatty acid (PUFA). Docosadienoic acid is an agonist of free fatty acid receptor 4 (FFAR4, also known as GPR120) and strongly inhibits the secretion of ghrelin by isolated mouse gastric cells.{32737}
Brand:CaymanSKU:20602 -Available on backorder
Docosadienoic acid methyl ester is an esterified version of 13Z,16Z-docosadienoic acid (Item No. 20749), which is a natural ω-6 polyunsaturated fatty acid (PUFA). Docosadienoic acid is an agonist of free fatty acid receptor 4 (FFAR4, also known as GPR120) and strongly inhibits the secretion of ghrelin by isolated mouse gastric cells.{32737}
Brand:CaymanSKU:20602 -Available on backorder
Docosaenoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids.{1202,1712,13153} This long-chain ethanolamine has been detected at relatively high levels in rat cerebrospinal fluid and has been used to examine the function of voltage-dependent Ca2+ channels in skeletal muscle membranes.{22439,13759}
Brand:CaymanSKU:9001745 - 10 mgAvailable on backorder
Docosaenoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids.{1202,1712,13153} This long-chain ethanolamine has been detected at relatively high levels in rat cerebrospinal fluid and has been used to examine the function of voltage-dependent Ca2+ channels in skeletal muscle membranes.{22439,13759}
Brand:CaymanSKU:9001745 - 5 mgAvailable on backorder
Docosaenoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids.{1202,1712,13153} This long-chain ethanolamine has been detected at relatively high levels in rat cerebrospinal fluid and has been used to examine the function of voltage-dependent Ca2+ channels in skeletal muscle membranes.{22439,13759}
Brand:CaymanSKU:9001745 - 50 mgAvailable on backorder
DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}
Brand:CaymanSKU:90310 - 100 mgAvailable on backorder
DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}
Brand:CaymanSKU:90310 - 250 mgAvailable on backorder
DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}
Brand:CaymanSKU:90310 - 50 mgAvailable on backorder
DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}
Brand:CaymanSKU:90310 - 500 mgAvailable on backorder
Fish oils in the diet have anti-inflammatory and cardiovascular benefits due to an abundance of ω-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA).{16509} DHA is the most abundant ω-3 PUFA in neural tissues, especially in the retina and brain. DHA ethyl ester is the stabilized ethyl ester form of the ω-3 22:6 fatty acid. Dietary intake of DHA ethyl ester enhances maze-learning ability in old mice.{16512} In rats, dietary DHA ethyl ester increases plasma and erythrocyte membrane DHA levels without altering the content of the ω-6 arachidonic acid.{16510} Dietary DHA ethyl ester increases fatty acid oxidation enzymes in rats and, in humans with peroxisomal disorders, improves vision, liver function, muscle tone, and social contact.{16514,16511} The ω-3 fatty acid eicosapentaenoic acid competitively inhibits the metabolism of arachidonic acid by COX enzymes, suggesting that DHA ethyl ester may also directly modulate the actions of enzymes involved in fatty acid metabolism.{16250}
Brand:CaymanSKU:9090310 - 1 gAvailable on backorder
Fish oils in the diet have anti-inflammatory and cardiovascular benefits due to an abundance of ω-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA).{16509} DHA is the most abundant ω-3 PUFA in neural tissues, especially in the retina and brain. DHA ethyl ester is the stabilized ethyl ester form of the ω-3 22:6 fatty acid. Dietary intake of DHA ethyl ester enhances maze-learning ability in old mice.{16512} In rats, dietary DHA ethyl ester increases plasma and erythrocyte membrane DHA levels without altering the content of the ω-6 arachidonic acid.{16510} Dietary DHA ethyl ester increases fatty acid oxidation enzymes in rats and, in humans with peroxisomal disorders, improves vision, liver function, muscle tone, and social contact.{16514,16511} The ω-3 fatty acid eicosapentaenoic acid competitively inhibits the metabolism of arachidonic acid by COX enzymes, suggesting that DHA ethyl ester may also directly modulate the actions of enzymes involved in fatty acid metabolism.{16250}
Brand:CaymanSKU:9090310 - 100 mgAvailable on backorder
Fish oils in the diet have anti-inflammatory and cardiovascular benefits due to an abundance of ω-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA).{16509} DHA is the most abundant ω-3 PUFA in neural tissues, especially in the retina and brain. DHA ethyl ester is the stabilized ethyl ester form of the ω-3 22:6 fatty acid. Dietary intake of DHA ethyl ester enhances maze-learning ability in old mice.{16512} In rats, dietary DHA ethyl ester increases plasma and erythrocyte membrane DHA levels without altering the content of the ω-6 arachidonic acid.{16510} Dietary DHA ethyl ester increases fatty acid oxidation enzymes in rats and, in humans with peroxisomal disorders, improves vision, liver function, muscle tone, and social contact.{16514,16511} The ω-3 fatty acid eicosapentaenoic acid competitively inhibits the metabolism of arachidonic acid by COX enzymes, suggesting that DHA ethyl ester may also directly modulate the actions of enzymes involved in fatty acid metabolism.{16250}
Brand:CaymanSKU:9090310 - 50 mgAvailable on backorder
Fish oils in the diet have anti-inflammatory and cardiovascular benefits due to an abundance of ω-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA).{16509} DHA is the most abundant ω-3 PUFA in neural tissues, especially in the retina and brain. DHA ethyl ester is the stabilized ethyl ester form of the ω-3 22:6 fatty acid. Dietary intake of DHA ethyl ester enhances maze-learning ability in old mice.{16512} In rats, dietary DHA ethyl ester increases plasma and erythrocyte membrane DHA levels without altering the content of the ω-6 arachidonic acid.{16510} Dietary DHA ethyl ester increases fatty acid oxidation enzymes in rats and, in humans with peroxisomal disorders, improves vision, liver function, muscle tone, and social contact.{16514,16511} The ω-3 fatty acid eicosapentaenoic acid competitively inhibits the metabolism of arachidonic acid by COX enzymes, suggesting that DHA ethyl ester may also directly modulate the actions of enzymes involved in fatty acid metabolism.{16250}
Brand:CaymanSKU:9090310 - 500 mgAvailable on backorder
Docosahexaenoic acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856} DHA MaxSpec® standard is a quantitative grade standard of DHA (Item No. 90310) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This DHA MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Brand:CaymanSKU:26414 - 1 mgAvailable on backorder
Docosahexaenoic acid (DHA) methyl ester is an esterified form of DHA (Item No. 90310). It has been used as a reference standard in the quantification of fatty acids in microalgal and fish oils.{54169}
Brand:CaymanSKU:10006865 - 1 gAvailable on backorder
Docosahexaenoic acid (DHA) methyl ester is an esterified form of DHA (Item No. 90310). It has been used as a reference standard in the quantification of fatty acids in microalgal and fish oils.{54169}
Brand:CaymanSKU:10006865 - 100 mgAvailable on backorder
Docosahexaenoic acid (DHA) methyl ester is an esterified form of DHA (Item No. 90310). It has been used as a reference standard in the quantification of fatty acids in microalgal and fish oils.{54169}
Brand:CaymanSKU:10006865 - 50 mgAvailable on backorder
Docosahexaenoic acid (DHA) methyl ester is an esterified form of DHA (Item No. 90310). It has been used as a reference standard in the quantification of fatty acids in microalgal and fish oils.{54169}
Brand:CaymanSKU:10006865 - 500 mgAvailable on backorder
Docosahexaenoic Acid-d5 (DHA-d5) contains five deuterium atoms at the 21, 21, 22, 22 and 22 positions. It is intended for use as an internal standard for the quantification of DHA (Item No. 90310) by GC- or LC-mass spectrometry. DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total polyunsaturated fatty acid pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}
Brand:CaymanSKU:10005057 - 1 mgAvailable on backorder
Docosahexaenoic Acid-d5 (DHA-d5) contains five deuterium atoms at the 21, 21, 22, 22 and 22 positions. It is intended for use as an internal standard for the quantification of DHA (Item No. 90310) by GC- or LC-mass spectrometry. DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total polyunsaturated fatty acid pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}
Brand:CaymanSKU:10005057 - 100 µgAvailable on backorder
Docosahexaenoic Acid-d5 (DHA-d5) contains five deuterium atoms at the 21, 21, 22, 22 and 22 positions. It is intended for use as an internal standard for the quantification of DHA (Item No. 90310) by GC- or LC-mass spectrometry. DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total polyunsaturated fatty acid pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}
Brand:CaymanSKU:10005057 - 50 µgAvailable on backorder
Docosahexaenoic Acid-d5 (DHA-d5) contains five deuterium atoms at the 21, 21, 22, 22 and 22 positions. It is intended for use as an internal standard for the quantification of DHA (Item No. 90310) by GC- or LC-mass spectrometry. DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total polyunsaturated fatty acid pool in retinal and neuronal membranes.{10297} Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays photoreceptor degeneration in retinitis pigmentosa.{1934} Neonatal DHA deprivation causes developmental defects and can lead to hypertension in rats.{8856}
Brand:CaymanSKU:10005057 - 500 µgAvailable on backorder
Docosahexaenoic acid-d5 (DHA-d5) is intended for use as an internal standard for the quantification of DHA (Item No. 90310) by GC- or LC-MS. DHA is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain.{10297} DHA constitutes as much as 40% of the total polyunsaturated fatty acid pool in retinal and neuronal membranes. Neonatal DHA deprivation leads to developmental defects and can lead to hypertension in rats.{8856} DHA-d5 MaxSpec® standard is a quantitative grade standard of DHA-d5 (Item No. 10005057) that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This DHA-d5 MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.
Brand:CaymanSKU:27357 - 100 µgAvailable on backorder
Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with docosahexaenoic acid (DHA) compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki of 324 nM, which is approximately 10-fold higher than the Ki for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 of 1.5 µM.{13859}
Brand:CaymanSKU:10007534 - 10 mgAvailable on backorder
Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with docosahexaenoic acid (DHA) compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki of 324 nM, which is approximately 10-fold higher than the Ki for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 of 1.5 µM.{13859}
Brand:CaymanSKU:10007534 - 25 mgAvailable on backorder
Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with docosahexaenoic acid (DHA) compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki of 324 nM, which is approximately 10-fold higher than the Ki for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 of 1.5 µM.{13859}
Brand:CaymanSKU:10007534 - 5 mgAvailable on backorder
Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with docosahexaenoic acid (DHA) compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki of 324 nM, which is approximately 10-fold higher than the Ki for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 of 1.5 µM.{13859}
Brand:CaymanSKU:10007534 - 50 mgAvailable on backorder
Docosahexaenoyl ethanolamide-d4 contains four deuterium atoms at the 1, 1′, 2, and 2′ positions. It is intended for use as an internal standard for the quantification of docosahexaenoyl ethanolamide by GC- or LC-mass spectrometry (MS). Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with DHA compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki value of 324 nM, which is approximately 10-fold higher than the Ki value for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 value of 1.5 µM.{13859}
Brand:CaymanSKU:9001108 - 1 mgAvailable on backorder
Docosahexaenoyl ethanolamide-d4 contains four deuterium atoms at the 1, 1′, 2, and 2′ positions. It is intended for use as an internal standard for the quantification of docosahexaenoyl ethanolamide by GC- or LC-mass spectrometry (MS). Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with DHA compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki value of 324 nM, which is approximately 10-fold higher than the Ki value for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 value of 1.5 µM.{13859}
Brand:CaymanSKU:9001108 - 10 mgAvailable on backorder
Docosahexaenoyl ethanolamide-d4 contains four deuterium atoms at the 1, 1′, 2, and 2′ positions. It is intended for use as an internal standard for the quantification of docosahexaenoyl ethanolamide by GC- or LC-mass spectrometry (MS). Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with DHA compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki value of 324 nM, which is approximately 10-fold higher than the Ki value for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 value of 1.5 µM.{13859}
Brand:CaymanSKU:9001108 - 5 mgAvailable on backorder
Docosahexaenoyl ethanolamide-d4 contains four deuterium atoms at the 1, 1′, 2, and 2′ positions. It is intended for use as an internal standard for the quantification of docosahexaenoyl ethanolamide by GC- or LC-mass spectrometry (MS). Docosahexaenoic Acid (DHA) is an essential fatty acid and the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. Docosahexaenoyl ethanolamide (DHEA) is the ethanolamine amide of DHA that has been detected in both brain and retina at concentrations similar to those for arachidonoyl ethanolamide (AEA).{3424,10520} A 9.5 fold increase of DHEA was observed in brain lipid extracts from piglets fed a diet supplemented with DHA compared to a control diet without DHA.{13860} DHEA binds to the rat brain CB1 receptor with a Ki value of 324 nM, which is approximately 10-fold higher than the Ki value for AEA.{9580} DHEA inhibits shaker-related voltage-gated potassium channels in brain slightly better than AEA, with an IC50 value of 1.5 µM.{13859}
Brand:CaymanSKU:9001108 - 500 µgAvailable on backorder
The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Docosahexaenoic acid (DHA), a C22:6 PUFA, is the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. It can be synthesized from other dietary ω-3 PUFAs or taken as a nutritional supplement. Docosahexaenoyl glycine consists of DHA with glycine attached at its carboxy terminus.
Brand:CaymanSKU:9000328 - 10 mgAvailable on backorder
The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Docosahexaenoic acid (DHA), a C22:6 PUFA, is the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. It can be synthesized from other dietary ω-3 PUFAs or taken as a nutritional supplement. Docosahexaenoyl glycine consists of DHA with glycine attached at its carboxy terminus.
Brand:CaymanSKU:9000328 - 100 mgAvailable on backorder
The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Docosahexaenoic acid (DHA), a C22:6 PUFA, is the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. It can be synthesized from other dietary ω-3 PUFAs or taken as a nutritional supplement. Docosahexaenoyl glycine consists of DHA with glycine attached at its carboxy terminus.
Brand:CaymanSKU:9000328 - 5 mgAvailable on backorder
The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Docosahexaenoic acid (DHA), a C22:6 PUFA, is the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. It can be synthesized from other dietary ω-3 PUFAs or taken as a nutritional supplement. Docosahexaenoyl glycine consists of DHA with glycine attached at its carboxy terminus.
Brand:CaymanSKU:9000328 - 50 mgAvailable on backorder
Docosahexaenoyl PAF C-16 is a PAF analog which contains docosahexaenoate at the sn-2 position rather than the acetate moiety found in PAF C-16. Docosahexaenoyl PAF C-16 can be oxidatively fragmented resulting in the production of phospholipids with PAF-like activity.{1938,2654}
Brand:CaymanSKU:60903 - 1 mgAvailable on backorder
Docosahexaenoyl PAF C-16 is a PAF analog which contains docosahexaenoate at the sn-2 position rather than the acetate moiety found in PAF C-16. Docosahexaenoyl PAF C-16 can be oxidatively fragmented resulting in the production of phospholipids with PAF-like activity.{1938,2654}
Brand:CaymanSKU:60903 - 10 mgAvailable on backorder
Docosahexaenoyl PAF C-16 is a PAF analog which contains docosahexaenoate at the sn-2 position rather than the acetate moiety found in PAF C-16. Docosahexaenoyl PAF C-16 can be oxidatively fragmented resulting in the production of phospholipids with PAF-like activity.{1938,2654}
Brand:CaymanSKU:60903 - 25 mgAvailable on backorder
Docosahexaenoyl PAF C-16 is a PAF analog which contains docosahexaenoate at the sn-2 position rather than the acetate moiety found in PAF C-16. Docosahexaenoyl PAF C-16 can be oxidatively fragmented resulting in the production of phospholipids with PAF-like activity.{1938,2654}
Brand:CaymanSKU:60903 - 5 mgAvailable on backorder
Docosahexaenoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (Catalog No. 70665). Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid 1 (TRPV1) channel, reducing both acute and chronic peripheral pain.{18121,18122} The effects of replacing the arachidonoyl portion with docosahexaenoyl have not been studied.
Brand:CaymanSKU:9000639 - 10 mgAvailable on backorder
Docosahexaenoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (Catalog No. 70665). Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid 1 (TRPV1) channel, reducing both acute and chronic peripheral pain.{18121,18122} The effects of replacing the arachidonoyl portion with docosahexaenoyl have not been studied.
Brand:CaymanSKU:9000639 - 100 mgAvailable on backorder
Docosahexaenoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (Catalog No. 70665). Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid 1 (TRPV1) channel, reducing both acute and chronic peripheral pain.{18121,18122} The effects of replacing the arachidonoyl portion with docosahexaenoyl have not been studied.
Brand:CaymanSKU:9000639 - 5 mgAvailable on backorder
Docosahexaenoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (Catalog No. 70665). Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid 1 (TRPV1) channel, reducing both acute and chronic peripheral pain.{18121,18122} The effects of replacing the arachidonoyl portion with docosahexaenoyl have not been studied.
Brand:CaymanSKU:9000639 - 50 mgAvailable on backorder
Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.{48322,48323} It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM).{31533} Docosanoic acid inhibits rat DNA polymerase β and human DNA polymerase λ activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM.{39264} Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet but not a high-cholesterol diet.{48324} Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.
Brand:CaymanSKU:9000338 - 1 gAvailable on backorder
Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.{48322,48323} It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM).{31533} Docosanoic acid inhibits rat DNA polymerase β and human DNA polymerase λ activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM.{39264} Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet but not a high-cholesterol diet.{48324} Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.
Brand:CaymanSKU:9000338 - 5 gAvailable on backorder
Docosanoic acid is a long-chain saturated fatty acid. It has been found in peanut and M. oleifera seed oils.{48322,48323} It inhibits the double-stranded DNA binding activity of p53 through a direct interaction with the DNA binding domain (Kd = 12 nM).{31533} Docosanoic acid inhibits rat DNA polymerase β and human DNA polymerase λ activity in cell-free enzyme assays when used at a concentration of 100 µM and inhibits human DNA topoisomerase I and II relaxation activity at a concentration of 25 µM.{39264} Liver levels of docosanoic acid are reduced in rats fed a high-fat or a high-fat high-cholesterol diet but not a high-cholesterol diet.{48324} Formulations containing docosanoic acid have been used in hair conditioner and moisturizers.
Brand:CaymanSKU:9000338 - 500 mgAvailable on backorder