Cayman
Showing 18451–18600 of 45550 results
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Dioctanoin is a diacylglycerol that contains the saturated short-chain fatty acid octanoic acid at two positions.
Brand:CaymanSKU:26982 - 250 mgAvailable on backorder
Dioctanoin is a diacylglycerol that contains the saturated short-chain fatty acid octanoic acid at two positions.
Brand:CaymanSKU:26982 - 50 mgAvailable on backorder
Dioctanoin is a diacylglycerol that contains the saturated short-chain fatty acid octanoic acid at two positions.
Brand:CaymanSKU:26982 - 500 mgAvailable on backorder
Dioctanoyl glycol is a diacylglycerol kinase (DGK) inhibitor (Ki = 58 μM).{5896} It reduces basal and thrombin-stimulated phosphatidic acid levels in washed isolated human platelets when used at concentrations of 30, 100, and 500 μM. Dietary administration of dioctanoyl glycol inhibits the growth of S. litura and H. armigera second instar larvae (EC50s = 1.98 and 2.08 mg/ml, respectively) and induces mortality when applied as a spray (LC50s = 6.1 and 6.5 mg/ml, respectively).{54398}
Brand:CaymanSKU:31515 - 10 mgAvailable on backorder
Dioctanoyl glycol is a diacylglycerol kinase (DGK) inhibitor (Ki = 58 μM).{5896} It reduces basal and thrombin-stimulated phosphatidic acid levels in washed isolated human platelets when used at concentrations of 30, 100, and 500 μM. Dietary administration of dioctanoyl glycol inhibits the growth of S. litura and H. armigera second instar larvae (EC50s = 1.98 and 2.08 mg/ml, respectively) and induces mortality when applied as a spray (LC50s = 6.1 and 6.5 mg/ml, respectively).{54398}
Brand:CaymanSKU:31515 - 25 mgAvailable on backorder
Dioctanoyl glycol is a diacylglycerol kinase (DGK) inhibitor (Ki = 58 μM).{5896} It reduces basal and thrombin-stimulated phosphatidic acid levels in washed isolated human platelets when used at concentrations of 30, 100, and 500 μM. Dietary administration of dioctanoyl glycol inhibits the growth of S. litura and H. armigera second instar larvae (EC50s = 1.98 and 2.08 mg/ml, respectively) and induces mortality when applied as a spray (LC50s = 6.1 and 6.5 mg/ml, respectively).{54398}
Brand:CaymanSKU:31515 - 5 mgAvailable on backorder
Dioctanoyl glycol is a diacylglycerol kinase (DGK) inhibitor (Ki = 58 μM).{5896} It reduces basal and thrombin-stimulated phosphatidic acid levels in washed isolated human platelets when used at concentrations of 30, 100, and 500 μM. Dietary administration of dioctanoyl glycol inhibits the growth of S. litura and H. armigera second instar larvae (EC50s = 1.98 and 2.08 mg/ml, respectively) and induces mortality when applied as a spray (LC50s = 6.1 and 6.5 mg/ml, respectively).{54398}
Brand:CaymanSKU:31515 - 50 mgAvailable on backorder
Diolein is a diacylglycerol that contains the monounsaturated 18-carbon fatty acid oleic acid (Item Nos. 90260 | 24659) at two positions.
Brand:CaymanSKU:26976 - 100 mgAvailable on backorder
Diolein is a diacylglycerol that contains the monounsaturated 18-carbon fatty acid oleic acid (Item Nos. 90260 | 24659) at two positions.
Brand:CaymanSKU:26976 - 25 mgAvailable on backorder
Diolein is a diacylglycerol that contains the monounsaturated 18-carbon fatty acid oleic acid (Item Nos. 90260 | 24659) at two positions.
Brand:CaymanSKU:26976 - 250 mgAvailable on backorder
Diolein is a diacylglycerol that contains the monounsaturated 18-carbon fatty acid oleic acid (Item Nos. 90260 | 24659) at two positions.
Brand:CaymanSKU:26976 - 50 mgAvailable on backorder
Dios-Arg is a steroid-based cationic lipid that contains a diosgenin skeleton coupled to an L-arginine head group.{47130} It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratio greater than or equal to 4.{44005} Dios-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence and absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin (Item No. 21633) and the caveolae-mediated endocytosis inhibitor genistein (Item No. 10005167). It has been used, coupled to 1,2-dioleoyl-sn-glycero-3-PE (DOPE; Item No. 15091), to bind siRNA and plasmid DNA to form cationic lipid nanoparticles for intracellular transport. Dios-Arg is cytotoxic to H1299 and HeLa cells (IC50s = 83.5 and 74.1 µg/ml, respectively).{44005}
Brand:CaymanSKU:25945 - 1 mgAvailable on backorder
Dios-Arg is a steroid-based cationic lipid that contains a diosgenin skeleton coupled to an L-arginine head group.{47130} It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratio greater than or equal to 4.{44005} Dios-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence and absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin (Item No. 21633) and the caveolae-mediated endocytosis inhibitor genistein (Item No. 10005167). It has been used, coupled to 1,2-dioleoyl-sn-glycero-3-PE (DOPE; Item No. 15091), to bind siRNA and plasmid DNA to form cationic lipid nanoparticles for intracellular transport. Dios-Arg is cytotoxic to H1299 and HeLa cells (IC50s = 83.5 and 74.1 µg/ml, respectively).{44005}
Brand:CaymanSKU:25945 - 10 mgAvailable on backorder
Dios-Arg is a steroid-based cationic lipid that contains a diosgenin skeleton coupled to an L-arginine head group.{47130} It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratio greater than or equal to 4.{44005} Dios-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence and absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin (Item No. 21633) and the caveolae-mediated endocytosis inhibitor genistein (Item No. 10005167). It has been used, coupled to 1,2-dioleoyl-sn-glycero-3-PE (DOPE; Item No. 15091), to bind siRNA and plasmid DNA to form cationic lipid nanoparticles for intracellular transport. Dios-Arg is cytotoxic to H1299 and HeLa cells (IC50s = 83.5 and 74.1 µg/ml, respectively).{44005}
Brand:CaymanSKU:25945 - 5 mgAvailable on backorder
Dioscin is a natural steroid saponin that was first isolated from plants used in herbal remedies.{34440} Early studies indicated that it inhibits proliferation and induces apoptosis in cancer cells.{34438,344440} Dioscin has antioxidant activity that can alter cell signaling in cancer cells.{30137,34441} It also induces autophagy prior to apoptosis in human lung cancer cell lines.{34439}
Brand:CaymanSKU:11834 - 10 mgAvailable on backorder
Dioscin is a natural steroid saponin that was first isolated from plants used in herbal remedies.{34440} Early studies indicated that it inhibits proliferation and induces apoptosis in cancer cells.{34438,344440} Dioscin has antioxidant activity that can alter cell signaling in cancer cells.{30137,34441} It also induces autophagy prior to apoptosis in human lung cancer cell lines.{34439}
Brand:CaymanSKU:11834 - 100 mgAvailable on backorder
Dioscin is a natural steroid saponin that was first isolated from plants used in herbal remedies.{34440} Early studies indicated that it inhibits proliferation and induces apoptosis in cancer cells.{34438,344440} Dioscin has antioxidant activity that can alter cell signaling in cancer cells.{30137,34441} It also induces autophagy prior to apoptosis in human lung cancer cell lines.{34439}
Brand:CaymanSKU:11834 - 25 mgAvailable on backorder
Dioscin is a natural steroid saponin that was first isolated from plants used in herbal remedies.{34440} Early studies indicated that it inhibits proliferation and induces apoptosis in cancer cells.{34438,344440} Dioscin has antioxidant activity that can alter cell signaling in cancer cells.{30137,34441} It also induces autophagy prior to apoptosis in human lung cancer cell lines.{34439}
Brand:CaymanSKU:11834 - 50 mgAvailable on backorder
Diosgenin is a natural steroid sapogenin that has diverse biochemical and physiological actions. It has antioxidant and anti-inflammatory activities, is protective against metabolic and cardiovascular diseases, and can have immunomodulatory and estrogenic effects.{30137,25923,31789,31790}
Brand:CaymanSKU:19847 -Available on backorder
Diosgenin is a natural steroid sapogenin that has diverse biochemical and physiological actions. It has antioxidant and anti-inflammatory activities, is protective against metabolic and cardiovascular diseases, and can have immunomodulatory and estrogenic effects.{30137,25923,31789,31790}
Brand:CaymanSKU:19847 -Available on backorder
Diosgenin is a natural steroid sapogenin that has diverse biochemical and physiological actions. It has antioxidant and anti-inflammatory activities, is protective against metabolic and cardiovascular diseases, and can have immunomodulatory and estrogenic effects.{30137,25923,31789,31790}
Brand:CaymanSKU:19847 -Available on backorder
Diosgenin is a natural steroid sapogenin that has diverse biochemical and physiological actions. It has antioxidant and anti-inflammatory activities, is protective against metabolic and cardiovascular diseases, and can have immunomodulatory and estrogenic effects.{30137,25923,31789,31790}
Brand:CaymanSKU:19847 -Available on backorder
(Item No. 10004161) Diosmetin is a flavonoid that has been found in citrus fruits and has diverse biological activities.{30253,49507,49508,49509} It inhibits the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1B1 (Kis = 89 and 16 nM, respectively).{30253} Diosmetin prevents increases in erythrocyte reactive oxygen species (ROS) and malondialdehyde (MDA) levels induced by AAPH (Item No. 82235) in a concentration-dependent manner.{49507} It reduces tumor growth and tumor blood vessel density in a B16/F10 murine melanoma model when administered at a dose of 1 mg/kg twice per day.{49508} Diosmetin (0.5 mg/kg) inhibits lung goblet cell hyperplasia and collagen deposition and decreases the number of eosinophils and neutrophils in bronchoalveolar lavage fluid (BALF) in a mouse model of chronic asthma induced by ovalbumin.{49509}
Brand:CaymanSKU:-Available on backorder
(Item No. 10004161) Diosmetin is a flavonoid that has been found in citrus fruits and has diverse biological activities.{30253,49507,49508,49509} It inhibits the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1B1 (Kis = 89 and 16 nM, respectively).{30253} Diosmetin prevents increases in erythrocyte reactive oxygen species (ROS) and malondialdehyde (MDA) levels induced by AAPH (Item No. 82235) in a concentration-dependent manner.{49507} It reduces tumor growth and tumor blood vessel density in a B16/F10 murine melanoma model when administered at a dose of 1 mg/kg twice per day.{49508} Diosmetin (0.5 mg/kg) inhibits lung goblet cell hyperplasia and collagen deposition and decreases the number of eosinophils and neutrophils in bronchoalveolar lavage fluid (BALF) in a mouse model of chronic asthma induced by ovalbumin.{49509}
Brand:CaymanSKU:-Available on backorder
(Item No. 10004161) Diosmetin is a flavonoid that has been found in citrus fruits and has diverse biological activities.{30253,49507,49508,49509} It inhibits the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1B1 (Kis = 89 and 16 nM, respectively).{30253} Diosmetin prevents increases in erythrocyte reactive oxygen species (ROS) and malondialdehyde (MDA) levels induced by AAPH (Item No. 82235) in a concentration-dependent manner.{49507} It reduces tumor growth and tumor blood vessel density in a B16/F10 murine melanoma model when administered at a dose of 1 mg/kg twice per day.{49508} Diosmetin (0.5 mg/kg) inhibits lung goblet cell hyperplasia and collagen deposition and decreases the number of eosinophils and neutrophils in bronchoalveolar lavage fluid (BALF) in a mouse model of chronic asthma induced by ovalbumin.{49509}
Brand:CaymanSKU:-Available on backorder
(Item No. 10004161) Diosmetin is a flavonoid that has been found in citrus fruits and has diverse biological activities.{30253,49507,49508,49509} It inhibits the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1B1 (Kis = 89 and 16 nM, respectively).{30253} Diosmetin prevents increases in erythrocyte reactive oxygen species (ROS) and malondialdehyde (MDA) levels induced by AAPH (Item No. 82235) in a concentration-dependent manner.{49507} It reduces tumor growth and tumor blood vessel density in a B16/F10 murine melanoma model when administered at a dose of 1 mg/kg twice per day.{49508} Diosmetin (0.5 mg/kg) inhibits lung goblet cell hyperplasia and collagen deposition and decreases the number of eosinophils and neutrophils in bronchoalveolar lavage fluid (BALF) in a mouse model of chronic asthma induced by ovalbumin.{49509}
Brand:CaymanSKU:-Available on backorder
Diosmetin-d3 is intended for use as an internal standard for the quantification of diosmetin (Item No. 18649) by GC- or LC-MS. Diosmetin is a flavonoid that has been found in citrus fruits and has diverse biological activities.{30253,49507,49508,49509} It inhibits the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1B1 (Kis = 89 and 16 nM, respectively).{30253} Diosmetin prevents increases in erythrocyte reactive oxygen species (ROS) and malondialdehyde (MDA) levels induced by AAPH (Item No. 82235) in a concentration-dependent manner.{49507} It reduces tumor growth and tumor blood vessel density in a B16/F10 murine melanoma model when administered at a dose of 1 mg/kg twice per day.{49508} Diosmetin (0.5 mg/kg) inhibits lung goblet cell hyperplasia and collagen deposition and decreases the number of eosinophils and neutrophils in bronchoalveolar lavage fluid (BALF) in a mouse model of chronic asthma induced by ovalbumin.{49509}
Brand:CaymanSKU:30122 - 1 mgAvailable on backorder
Diosmetin-d3 is intended for use as an internal standard for the quantification of diosmetin (Item No. 18649) by GC- or LC-MS. Diosmetin is a flavonoid that has been found in citrus fruits and has diverse biological activities.{30253,49507,49508,49509} It inhibits the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1B1 (Kis = 89 and 16 nM, respectively).{30253} Diosmetin prevents increases in erythrocyte reactive oxygen species (ROS) and malondialdehyde (MDA) levels induced by AAPH (Item No. 82235) in a concentration-dependent manner.{49507} It reduces tumor growth and tumor blood vessel density in a B16/F10 murine melanoma model when administered at a dose of 1 mg/kg twice per day.{49508} Diosmetin (0.5 mg/kg) inhibits lung goblet cell hyperplasia and collagen deposition and decreases the number of eosinophils and neutrophils in bronchoalveolar lavage fluid (BALF) in a mouse model of chronic asthma induced by ovalbumin.{49509}
Brand:CaymanSKU:30122 - 500 µgAvailable on backorder
Diosmin is a flavonoid that has been found in citrus fruits and has diverse biological activities.{61083,61084,61085,61086,61087} It inhibits LPS-induced production of prostaglandin E2 (PGE2; Item No. 14010), nitric oxide (NO), IL-12, IL-6, and TNF-α in RAW 264.7 macrophages when used at concentrations ranging from 10 to 50 µM.{61083} Diosmin (100 mg/kg) reduces gastric ulcer area and leukocyte invasion in a rat model of ethanol-induced gastric injury.{61084} It decreases lung malondialdehyde (MDA) levels, increases lung glutathione (GSH) levels and catalase activity, and reduces fibrosis in a mouse model of paraquat-induced lung injury.{61085} Diosmin (50 and 100 mg/kg) increases the time spent in the goal quarter in a spatial memory test and reverses hippocampal dentate gyrus long term potentiation impairments in a rat model of scopolamine-induced cognitive impairment.{61086} It also reduces mechanical and thermal hyperalgesia in a rat model of neuropathic pain induced by chronic constriction injury.{61087}
Brand:CaymanSKU:19848 -Available on backorder
Diosmin is a flavonoid that has been found in citrus fruits and has diverse biological activities.{61083,61084,61085,61086,61087} It inhibits LPS-induced production of prostaglandin E2 (PGE2; Item No. 14010), nitric oxide (NO), IL-12, IL-6, and TNF-α in RAW 264.7 macrophages when used at concentrations ranging from 10 to 50 µM.{61083} Diosmin (100 mg/kg) reduces gastric ulcer area and leukocyte invasion in a rat model of ethanol-induced gastric injury.{61084} It decreases lung malondialdehyde (MDA) levels, increases lung glutathione (GSH) levels and catalase activity, and reduces fibrosis in a mouse model of paraquat-induced lung injury.{61085} Diosmin (50 and 100 mg/kg) increases the time spent in the goal quarter in a spatial memory test and reverses hippocampal dentate gyrus long term potentiation impairments in a rat model of scopolamine-induced cognitive impairment.{61086} It also reduces mechanical and thermal hyperalgesia in a rat model of neuropathic pain induced by chronic constriction injury.{61087}
Brand:CaymanSKU:19848 -Available on backorder
Diosmin is a flavonoid that has been found in citrus fruits and has diverse biological activities.{61083,61084,61085,61086,61087} It inhibits LPS-induced production of prostaglandin E2 (PGE2; Item No. 14010), nitric oxide (NO), IL-12, IL-6, and TNF-α in RAW 264.7 macrophages when used at concentrations ranging from 10 to 50 µM.{61083} Diosmin (100 mg/kg) reduces gastric ulcer area and leukocyte invasion in a rat model of ethanol-induced gastric injury.{61084} It decreases lung malondialdehyde (MDA) levels, increases lung glutathione (GSH) levels and catalase activity, and reduces fibrosis in a mouse model of paraquat-induced lung injury.{61085} Diosmin (50 and 100 mg/kg) increases the time spent in the goal quarter in a spatial memory test and reverses hippocampal dentate gyrus long term potentiation impairments in a rat model of scopolamine-induced cognitive impairment.{61086} It also reduces mechanical and thermal hyperalgesia in a rat model of neuropathic pain induced by chronic constriction injury.{61087}
Brand:CaymanSKU:19848 -Available on backorder
Dipalmitelaidin is a diacylglycerol that contains the monounsaturated 16-carbon fatty acid palmitelaidic acid (Item No. 9001798) at two positions.
Brand:CaymanSKU:26978 - 1 mgAvailable on backorder
Dipalmitelaidin is a diacylglycerol that contains the monounsaturated 16-carbon fatty acid palmitelaidic acid (Item No. 9001798) at two positions.
Brand:CaymanSKU:26978 - 10 mgAvailable on backorder
Dipalmitelaidin is a diacylglycerol that contains the monounsaturated 16-carbon fatty acid palmitelaidic acid (Item No. 9001798) at two positions.
Brand:CaymanSKU:26978 - 25 mgAvailable on backorder
Dipalmitelaidin is a diacylglycerol that contains the monounsaturated 16-carbon fatty acid palmitelaidic acid (Item No. 9001798) at two positions.
Brand:CaymanSKU:26978 - 5 mgAvailable on backorder
Dipalmitin is a diacylglycerol that contains the saturated 16-carbon fatty acid palmitic acid (Item No. 10006627) at two positions.
Brand:CaymanSKU:28172 - 100 mgAvailable on backorder
Dipalmitin is a diacylglycerol that contains the saturated 16-carbon fatty acid palmitic acid (Item No. 10006627) at two positions.
Brand:CaymanSKU:28172 - 250 mgAvailable on backorder
Dipalmitin is a diacylglycerol that contains the saturated 16-carbon fatty acid palmitic acid (Item No. 10006627) at two positions.
Brand:CaymanSKU:28172 - 500 mgAvailable on backorder
Dipalmitolein is a diacylglycerol that contains palmitoleic acid (Item Nos. 10009871 | 21911) at two positions.
Brand:CaymanSKU:26997 - 100 mgAvailable on backorder
Dipalmitolein is a diacylglycerol that contains palmitoleic acid (Item Nos. 10009871 | 21911) at two positions.
Brand:CaymanSKU:26997 - 25 mgAvailable on backorder
Dipalmitolein is a diacylglycerol that contains palmitoleic acid (Item Nos. 10009871 | 21911) at two positions.
Brand:CaymanSKU:26997 - 250 mgAvailable on backorder
Dipalmitolein is a diacylglycerol that contains palmitoleic acid (Item Nos. 10009871 | 21911) at two positions.
Brand:CaymanSKU:26997 - 50 mgAvailable on backorder
Dipentadecanoin is a diacylglycerol that contains pentadecanoic acid (Item No. 17399) at two positions.
Brand:CaymanSKU:27000 - 10 mgAvailable on backorder
Dipentadecanoin is a diacylglycerol that contains pentadecanoic acid (Item No. 17399) at two positions.
Brand:CaymanSKU:27000 - 100 mgAvailable on backorder
Dipentadecanoin is a diacylglycerol that contains pentadecanoic acid (Item No. 17399) at two positions.
Brand:CaymanSKU:27000 - 25 mgAvailable on backorder
Dipentadecanoin is a diacylglycerol that contains pentadecanoic acid (Item No. 17399) at two positions.
Brand:CaymanSKU:27000 - 50 mgAvailable on backorder
Dipeptide diaminobutyroyl benzylamide is a biomimetic peptide and a muscarinic acetylcholine receptor antagonist.{45360} It mimics the action of the temple viper (T. wagleri) venom peptide Waglerin-1 to block sodium uptake and induce muscle relaxation.
Brand:CaymanSKU:27566 - 1 gAvailable on backorder
Dipeptide diaminobutyroyl benzylamide is a biomimetic peptide and a muscarinic acetylcholine receptor antagonist.{45360} It mimics the action of the temple viper (T. wagleri) venom peptide Waglerin-1 to block sodium uptake and induce muscle relaxation.
Brand:CaymanSKU:27566 - 100 mgAvailable on backorder
Dipeptide diaminobutyroyl benzylamide is a biomimetic peptide and a muscarinic acetylcholine receptor antagonist.{45360} It mimics the action of the temple viper (T. wagleri) venom peptide Waglerin-1 to block sodium uptake and induce muscle relaxation.
Brand:CaymanSKU:27566 - 250 mgAvailable on backorder
Dipeptide diaminobutyroyl benzylamide is a biomimetic peptide and a muscarinic acetylcholine receptor antagonist.{45360} It mimics the action of the temple viper (T. wagleri) venom peptide Waglerin-1 to block sodium uptake and induce muscle relaxation.
Brand:CaymanSKU:27566 - 500 mgAvailable on backorder
Diphemanil is a quaternary ammonium anticholinergic agent.{53536} It induces relaxation of isolated guinea pig trachea strips precontracted with methacholine (EC50 = 0.12 nM). Diphemanil reverses increases in lung resistance and decreases in dynamic lung compliance induced by the non-selective acetylcholine receptor agonist carbachol (carbamoylcholine; Item No. 14486) in vagotomized cats (ED50s = 17.5 and 19.3 µg/kg, respectively). It reduces salivation induced by the muscarinic acetylcholine receptor agonist pilocarpine in mice when administered subcutaneously at doses ranging from 1.25 to 10 mg/kg.{53537}
Brand:CaymanSKU:30090 - 100 mgAvailable on backorder
Diphemanil is a quaternary ammonium anticholinergic agent.{53536} It induces relaxation of isolated guinea pig trachea strips precontracted with methacholine (EC50 = 0.12 nM). Diphemanil reverses increases in lung resistance and decreases in dynamic lung compliance induced by the non-selective acetylcholine receptor agonist carbachol (carbamoylcholine; Item No. 14486) in vagotomized cats (ED50s = 17.5 and 19.3 µg/kg, respectively). It reduces salivation induced by the muscarinic acetylcholine receptor agonist pilocarpine in mice when administered subcutaneously at doses ranging from 1.25 to 10 mg/kg.{53537}
Brand:CaymanSKU:30090 - 25 mgAvailable on backorder
Diphemanil is a quaternary ammonium anticholinergic agent.{53536} It induces relaxation of isolated guinea pig trachea strips precontracted with methacholine (EC50 = 0.12 nM). Diphemanil reverses increases in lung resistance and decreases in dynamic lung compliance induced by the non-selective acetylcholine receptor agonist carbachol (carbamoylcholine; Item No. 14486) in vagotomized cats (ED50s = 17.5 and 19.3 µg/kg, respectively). It reduces salivation induced by the muscarinic acetylcholine receptor agonist pilocarpine in mice when administered subcutaneously at doses ranging from 1.25 to 10 mg/kg.{53537}
Brand:CaymanSKU:30090 - 250 mgAvailable on backorder
Diphemanil is a quaternary ammonium anticholinergic agent.{53536} It induces relaxation of isolated guinea pig trachea strips precontracted with methacholine (EC50 = 0.12 nM). Diphemanil reverses increases in lung resistance and decreases in dynamic lung compliance induced by the non-selective acetylcholine receptor agonist carbachol (carbamoylcholine; Item No. 14486) in vagotomized cats (ED50s = 17.5 and 19.3 µg/kg, respectively). It reduces salivation induced by the muscarinic acetylcholine receptor agonist pilocarpine in mice when administered subcutaneously at doses ranging from 1.25 to 10 mg/kg.{53537}
Brand:CaymanSKU:30090 - 50 mgAvailable on backorder
Diphencyprone (DCP) is a contact sensitizing agent.{42859,42860,42861} Pretreatment with DCP reduces symptom severity in a mouse model of experimental autoimmune encephalomyelitis (EAE) induced by myelin basic protein (1-10) (MBP1-10).{42859} It enhances IL-10 production and antigen-specific IgG2a antibody responses and reduces anaphylaxis and asthma induced by ovalbumin in mice when administered during ovalbumin immunization at a concentration of 1% v/v.{42860} Topical administration of DCP increases intrafollicular CD4+ and CD8+ T cells, reduces upper dermal inflammation, and stimulates hair growth in the C3H/HeJ mouse model of alopecia areta.{42861} Formulations containing DCP have been used in the treatment of alopecia areta.
Brand:CaymanSKU:27982 - 1 gAvailable on backorder
Diphencyprone (DCP) is a contact sensitizing agent.{42859,42860,42861} Pretreatment with DCP reduces symptom severity in a mouse model of experimental autoimmune encephalomyelitis (EAE) induced by myelin basic protein (1-10) (MBP1-10).{42859} It enhances IL-10 production and antigen-specific IgG2a antibody responses and reduces anaphylaxis and asthma induced by ovalbumin in mice when administered during ovalbumin immunization at a concentration of 1% v/v.{42860} Topical administration of DCP increases intrafollicular CD4+ and CD8+ T cells, reduces upper dermal inflammation, and stimulates hair growth in the C3H/HeJ mouse model of alopecia areta.{42861} Formulations containing DCP have been used in the treatment of alopecia areta.
Brand:CaymanSKU:27982 - 10 gAvailable on backorder
Diphencyprone (DCP) is a contact sensitizing agent.{42859,42860,42861} Pretreatment with DCP reduces symptom severity in a mouse model of experimental autoimmune encephalomyelitis (EAE) induced by myelin basic protein (1-10) (MBP1-10).{42859} It enhances IL-10 production and antigen-specific IgG2a antibody responses and reduces anaphylaxis and asthma induced by ovalbumin in mice when administered during ovalbumin immunization at a concentration of 1% v/v.{42860} Topical administration of DCP increases intrafollicular CD4+ and CD8+ T cells, reduces upper dermal inflammation, and stimulates hair growth in the C3H/HeJ mouse model of alopecia areta.{42861} Formulations containing DCP have been used in the treatment of alopecia areta.
Brand:CaymanSKU:27982 - 5 gAvailable on backorder
Diphencyprone (DCP) is a contact sensitizing agent.{42859,42860,42861} Pretreatment with DCP reduces symptom severity in a mouse model of experimental autoimmune encephalomyelitis (EAE) induced by myelin basic protein (1-10) (MBP1-10).{42859} It enhances IL-10 production and antigen-specific IgG2a antibody responses and reduces anaphylaxis and asthma induced by ovalbumin in mice when administered during ovalbumin immunization at a concentration of 1% v/v.{42860} Topical administration of DCP increases intrafollicular CD4+ and CD8+ T cells, reduces upper dermal inflammation, and stimulates hair growth in the C3H/HeJ mouse model of alopecia areta.{42861} Formulations containing DCP have been used in the treatment of alopecia areta.
Brand:CaymanSKU:27982 - 500 mgAvailable on backorder
Diphenhydramine (hydrochloride) (Item No. 22489) is an analytical reference standard that is categorized as an antihistamine.{15199} It increases hallucinations and manic behavior associated with use of products marketed as bath salts.{36168} This product is intended for analytical forensic applications. This product is also available as a general research tool (Item No. 11158).
Brand:CaymanSKU:22489 -Out of stock
Diphenhydramine (DPH) is a first generation antihistamine that is a potent antagonist of the histamine H1 receptor (Ki = 11.7 nM using human recombinant receptors).{15199,22787} DPH readily crosses the blood-brain barrier and produces diverse cognitive and psychomotor effects.{15199,22788} DPH also antagonizes muscarinic cholinergic receptors (Kis = 100 to 260 nM for M1-M5), increasing the range of central nervous system effects and applications.{22786} This product is also available as an analytical reference standard (Item No. 22489).
Brand:CaymanSKU:11158 - 100 mgAvailable on backorder
Diphenhydramine (DPH) is a first generation antihistamine that is a potent antagonist of the histamine H1 receptor (Ki = 11.7 nM using human recombinant receptors).{15199,22787} DPH readily crosses the blood-brain barrier and produces diverse cognitive and psychomotor effects.{15199,22788} DPH also antagonizes muscarinic cholinergic receptors (Kis = 100 to 260 nM for M1-M5), increasing the range of central nervous system effects and applications.{22786} This product is also available as an analytical reference standard (Item No. 22489).
Brand:CaymanSKU:11158 - 250 mgAvailable on backorder
Diphenhydramine (hydrochloride) (Item No. 22489) is an analytical reference standard that is categorized as an antihistamine.{15199} It increases hallucinations and manic behavior associated with use of products marketed as bath salts.{36168} This product is intended for analytical forensic applications. This product is also available as a general research tool (Item No. 11158).
Brand:CaymanSKU:22489 -Out of stock
Diphenidine is a homeomorph of the NMDA receptor channel blocker, MK 801, that has been identified as a designer drug.{26258} The (S)- and (R)- enantiomers of diphenidine have been reported to inhibit MK 801 binding to NMDA receptors in rat brain membranes with Ki values of 0.13 and 5.25 µM, respectively.{26258} It has been studied as a neuroprotective agent for the treatment of brain injury following hypoxia.{26257} This product is intended for forensic and research applications.
Brand:CaymanSKU:- Diphenidine is a homeomorph of the NMDA receptor channel blocker, MK 801, that has been identified as a designer drug.{26258} The (S)- and (R)- enantiomers of diphenidine have been reported to inhibit MK 801 binding to NMDA receptors in rat brain membranes with Ki values of 0.13 and 5.25 µM, respectively.{26258} It has been studied as a neuroprotective agent for the treatment of brain injury following hypoxia.{26257} This product is intended for forensic and research applications.
Brand:CaymanSKU:- Diphenidine is a homeomorph of the NMDA receptor channel blocker, MK 801, that has been identified as a designer drug.{26258} The (S)- and (R)- enantiomers of diphenidine have been reported to inhibit MK 801 binding to NMDA receptors in rat brain membranes with Ki values of 0.13 and 5.25 µM, respectively.{26258} It has been studied as a neuroprotective agent for the treatment of brain injury following hypoxia.{26257} This product is intended for forensic and research applications.
Brand:CaymanSKU:-
Diphenidol is a non-selective muscarinic acetylcholine receptor antagonist.{30252} It is also a non-specific inhibitor of voltage-gated ion channels (Na+, K+, and Ca2+) in neurons.{30250} Diphenidol has been used to inhibit rotation-induced firing of type 1 medial vestibular nucleus neurons in a cat model of vertigo and to block the chemoreceptor trigger zone in the medulla that controls apomorphine-induced vomiting in a dog model of emesis.{30249,30251}
Brand:CaymanSKU:-Available on backorder
Diphenidol is a non-selective muscarinic acetylcholine receptor antagonist.{30252} It is also a non-specific inhibitor of voltage-gated ion channels (Na+, K+, and Ca2+) in neurons.{30250} Diphenidol has been used to inhibit rotation-induced firing of type 1 medial vestibular nucleus neurons in a cat model of vertigo and to block the chemoreceptor trigger zone in the medulla that controls apomorphine-induced vomiting in a dog model of emesis.{30249,30251}
Brand:CaymanSKU:-Available on backorder
Diphenidol is a non-selective muscarinic acetylcholine receptor antagonist.{30252} It is also a non-specific inhibitor of voltage-gated ion channels (Na+, K+, and Ca2+) in neurons.{30250} Diphenidol has been used to inhibit rotation-induced firing of type 1 medial vestibular nucleus neurons in a cat model of vertigo and to block the chemoreceptor trigger zone in the medulla that controls apomorphine-induced vomiting in a dog model of emesis.{30249,30251}
Brand:CaymanSKU:-Available on backorder
Diphenidol is a non-selective muscarinic acetylcholine receptor antagonist.{30252} It is also a non-specific inhibitor of voltage-gated ion channels (Na+, K+, and Ca2+) in neurons.{30250} Diphenidol has been used to inhibit rotation-induced firing of type 1 medial vestibular nucleus neurons in a cat model of vertigo and to block the chemoreceptor trigger zone in the medulla that controls apomorphine-induced vomiting in a dog model of emesis.{30249,30251}
Brand:CaymanSKU:-Available on backorder
Diphenylamine is an antioxidant that has been found in a variety of plants, including black and green tea plants, onion, and citrus.{37757,37758} It inhibits the oxidation of α-farnesene in solution as well as in the coating of Granny Smith apples.{37757} Diphenylamine (1,000 ppm) prevents superficial scald in several varieties of apples when applied by dipping or wrapping post-harvest.{37759} It induces toxicity in the aquatic organisms D. magna, P. phosphoreum, and V. fischeri (EC50s = 2.3, ~4.75, and ~5.5 mg/L, respectively).{37758} Diphenylamine has been used in colorimetric assays for the quantification of DNA.{37760} Formulations containing diphenylamine have been used to prevent deterioration of apple and pear crops post-harvest.
Brand:CaymanSKU:24250 - 5 gAvailable on backorder
Diphenyleneiodonium (DPI) is an irreversible inhibitor of iNOS and eNOS with IC50 values of 50 nM and 0.3 µM, respectively.{952} This inhibition is potent, irreversible, and time and temperature dependent.{952} NADPH, NADP+, and 2’5′-ADP blocks the inhibitory action of DPI. Similarly, FAD or FMN protect NOS from inhibition by DPI.{952}
Brand:CaymanSKU:81050 - 10 mgAvailable on backorder
Diphenyleneiodonium (DPI) is an irreversible inhibitor of iNOS and eNOS with IC50 values of 50 nM and 0.3 µM, respectively.{952} This inhibition is potent, irreversible, and time and temperature dependent.{952} NADPH, NADP+, and 2’5′-ADP blocks the inhibitory action of DPI. Similarly, FAD or FMN protect NOS from inhibition by DPI.{952}
Brand:CaymanSKU:81050 - 5 mgAvailable on backorder
The Wittig reaction is a frequently used method for olefin synthesis involving a phosphorane ylide and an aldehyde or ketone. DPP is a common by-product of this reaction. DPP can be used as a standard in analyzing products of synthetic routes that utilize the Wittig reaction.
Brand:CaymanSKU:10011337 - 10 mgAvailable on backorder
The Wittig reaction is a frequently used method for olefin synthesis involving a phosphorane ylide and an aldehyde or ketone. DPP is a common by-product of this reaction. DPP can be used as a standard in analyzing products of synthetic routes that utilize the Wittig reaction.
Brand:CaymanSKU:10011337 - 100 mgAvailable on backorder
The Wittig reaction is a frequently used method for olefin synthesis involving a phosphorane ylide and an aldehyde or ketone. DPP is a common by-product of this reaction. DPP can be used as a standard in analyzing products of synthetic routes that utilize the Wittig reaction.
Brand:CaymanSKU:10011337 - 5 mgAvailable on backorder
The Wittig reaction is a frequently used method for olefin synthesis involving a phosphorane ylide and an aldehyde or ketone. DPP is a common by-product of this reaction. DPP can be used as a standard in analyzing products of synthetic routes that utilize the Wittig reaction.
Brand:CaymanSKU:10011337 - 50 mgAvailable on backorder
Dipivefrin is a prodrug of epinephrine that is hydrolyzed by cholinesterase and other esterases in the cornea to epinephrine.{36428} It reduces the density of cultured bovine primary trabecular meshwork cells (IC50 = 115 µM).{36424} Additionally, it induces an elongated, fibroblast-like morphology and disrupts the actin cytoskeleton in bovine primary trabecular meshwork cells when used at a concentration of 103 µM.{36424} In cultured bovine corneal endothelial cells, dipivefrin (28 µM) enhances calcium signaling and induces cytotoxicity.{36426,36425} Dipivefrin also suppresses primary human corneal keratinocyte proliferation when used at a concentration of 280 µM.{36427} Formulations containing dipivefrin have been used alone and in combination with β-adrenergic receptor antagonists for the treatment of glaucoma.
Brand:CaymanSKU:24028 - 100 mgAvailable on backorder
Dipivefrin is a prodrug of epinephrine that is hydrolyzed by cholinesterase and other esterases in the cornea to epinephrine.{36428} It reduces the density of cultured bovine primary trabecular meshwork cells (IC50 = 115 µM).{36424} Additionally, it induces an elongated, fibroblast-like morphology and disrupts the actin cytoskeleton in bovine primary trabecular meshwork cells when used at a concentration of 103 µM.{36424} In cultured bovine corneal endothelial cells, dipivefrin (28 µM) enhances calcium signaling and induces cytotoxicity.{36426,36425} Dipivefrin also suppresses primary human corneal keratinocyte proliferation when used at a concentration of 280 µM.{36427} Formulations containing dipivefrin have been used alone and in combination with β-adrenergic receptor antagonists for the treatment of glaucoma.
Brand:CaymanSKU:24028 - 25 mgAvailable on backorder
Dipivefrin is a prodrug of epinephrine that is hydrolyzed by cholinesterase and other esterases in the cornea to epinephrine.{36428} It reduces the density of cultured bovine primary trabecular meshwork cells (IC50 = 115 µM).{36424} Additionally, it induces an elongated, fibroblast-like morphology and disrupts the actin cytoskeleton in bovine primary trabecular meshwork cells when used at a concentration of 103 µM.{36424} In cultured bovine corneal endothelial cells, dipivefrin (28 µM) enhances calcium signaling and induces cytotoxicity.{36426,36425} Dipivefrin also suppresses primary human corneal keratinocyte proliferation when used at a concentration of 280 µM.{36427} Formulations containing dipivefrin have been used alone and in combination with β-adrenergic receptor antagonists for the treatment of glaucoma.
Brand:CaymanSKU:24028 - 50 mgAvailable on backorder
Diproqualone (Item No. 21836) is an analytical reference standard. This product is intended for research and forensic applications.
Brand:CaymanSKU:21836 -Out of stock
Diproqualone (Item No. 21836) is an analytical reference standard. This product is intended for research and forensic applications.
Brand:CaymanSKU:21836 -Out of stock