Cayman
Showing 17851–18000 of 45550 results
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Desacetyl bisacodyl (DAB) is an active metabolite of two stimulant laxatives, bisacodyl and sodium picosulfate.{33526,33529} DAB evokes several effects at the colon or rectum, including increased mucus and chloride secretion.{33524,33525} Oral administration of bisacodyl leads to decreased expression of aquaporin-3 in the colon of rats.{33527} The effects of both DAB and bisacodyl can be blocked with cyclooxygenase (COX) inhibitors, suggesting that products of the COX signaling pathway contribute to laxative effects.{33525,33527}
Brand:CaymanSKU:20928 -Out of stock
Desacetyl cefapirin is an active metabolite of the cephalosporin antibiotic cefapirin (Item No. 17406).{43997} Desacetyl cefapirin is active against E. coli, K. pneumoniae, P. mirabilis, and S. aureus with MIC values of 120, 24, 34, and 0.42 µg/ml, respectively.
Brand:CaymanSKU:27578 - 1 mgAvailable on backorder
Desacetyl cefapirin is an active metabolite of the cephalosporin antibiotic cefapirin (Item No. 17406).{43997} Desacetyl cefapirin is active against E. coli, K. pneumoniae, P. mirabilis, and S. aureus with MIC values of 120, 24, 34, and 0.42 µg/ml, respectively.
Brand:CaymanSKU:27578 - 10 mgAvailable on backorder
Desacetyl cefapirin is an active metabolite of the cephalosporin antibiotic cefapirin (Item No. 17406).{43997} Desacetyl cefapirin is active against E. coli, K. pneumoniae, P. mirabilis, and S. aureus with MIC values of 120, 24, 34, and 0.42 µg/ml, respectively.
Brand:CaymanSKU:27578 - 25 mgAvailable on backorder
Desacetyl cefapirin is an active metabolite of the cephalosporin antibiotic cefapirin (Item No. 17406).{43997} Desacetyl cefapirin is active against E. coli, K. pneumoniae, P. mirabilis, and S. aureus with MIC values of 120, 24, 34, and 0.42 µg/ml, respectively.
Brand:CaymanSKU:27578 - 5 mgAvailable on backorder
Brand:CaymanSKU:29971 - 1 mgAvailable on backorder
Brand:CaymanSKU:29971 - 5 mgAvailable on backorder
deschloro-N-ethyl-Ketamine is an analog of the dissociative anesthetic ketamine (Item No. 11630). Ketamine and its analogs have been abused recreationally.{21236,21240,21237,25509} The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research purposes.
Brand:CaymanSKU:-deschloro-N-ethyl-Ketamine is an analog of the dissociative anesthetic ketamine (Item No. 11630). Ketamine and its analogs have been abused recreationally.{21236,21240,21237,25509} The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research purposes.
Brand:CaymanSKU:-deschloro-N-ethyl-Ketamine is an analog of the dissociative anesthetic ketamine (Item No. 11630). Ketamine and its analogs have been abused recreationally.{21236,21240,21237,25509} The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research purposes.
Brand:CaymanSKU:-Deschloroetizolam (Item No. 23107) is an analytical reference standard categorized as a thienodiazepine.{35230} This product is intended for research and forensic applications.
Brand:CaymanSKU:23107 - 1 mgAvailable on backorder
Deschloroetizolam (Item No. 23107) is an analytical reference standard categorized as a thienodiazepine.{35230} This product is intended for research and forensic applications.
Brand:CaymanSKU:23107 - 5 mgAvailable on backorder
Deschloronorketamine (hydrochloride) (Item No. 26401) is an analytical reference standard categorized as an arylcyclohexylamine. It is a metabolite of deschloroketamine (Item Nos. 25688 | 18683).{49018} This product is intended for research and forensic applications.
Brand:CaymanSKU:26401 - 1 mgAvailable on backorder
Deschloronorketamine (hydrochloride) (Item No. 26401) is an analytical reference standard categorized as an arylcyclohexylamine. It is a metabolite of deschloroketamine (Item Nos. 25688 | 18683).{49018} This product is intended for research and forensic applications.
Brand:CaymanSKU:26401 - 5 mgAvailable on backorder
Desertomycin A is fungal metabolite and the major component of the desertomycin antibiotic complex that has been found in S. flavofungini.{45261}
Brand:CaymanSKU:28169 - 1 mgAvailable on backorder
Desertomycin A is fungal metabolite and the major component of the desertomycin antibiotic complex that has been found in S. flavofungini.{45261}
Brand:CaymanSKU:28169 - 5 mgAvailable on backorder
Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine (Item No. 17911).{57098} It is formed via the desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.
Brand:CaymanSKU:31152 - 1 mgAvailable on backorder
Desethyl hydroxychloroquine-d4 is intended for use as an internal standard for the quantification of desethyl hydroxychloroquine (Item No. 31152) by GC- or LC-MS. Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine (Item No. 17911).{57098} It is formed via the desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.
Brand:CaymanSKU:31162 - 1 mgAvailable on backorder
Desethyl hydroxychloroquine-d4 is intended for use as an internal standard for the quantification of desethyl hydroxychloroquine (Item No. 31152) by GC- or LC-MS. Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine (Item No. 17911).{57098} It is formed via the desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.
Brand:CaymanSKU:31162 - 5 mgAvailable on backorder
Desethyl hydroxychloroquine-d4 is intended for use as an internal standard for the quantification of desethyl hydroxychloroquine (Item No. 31152) by GC- or LC-MS. Desethyl hydroxychloroquine is an active metabolite of hydroxychloroquine (Item No. 17911).{57098} It is formed via the desethylation of hydroxychloroquine in the liver, a process mediated by the cytochrome P450 (CYP) isoforms CYP2D6, CYP3A4, CYP3A5, and CYP2C8.
Brand:CaymanSKU:31162 - 500 µgAvailable on backorder
Desethylchloroquine is a major active metabolite of chloroquine (Item No. 14194).{52376} Desethylchloroquine is formed when chloroquine undergoes dealkylation, primarily by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP3A4 and to a lesser extent by CYP2D6. It inhibits the growth of the P. falciparum strain LA136 in vitro (IC50 = 9.9 ng/ml).{52377}
Brand:CaymanSKU:30113 - 1 mgAvailable on backorder
Desethylchloroquine is a major active metabolite of chloroquine (Item No. 14194).{52376} Desethylchloroquine is formed when chloroquine undergoes dealkylation, primarily by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP3A4 and to a lesser extent by CYP2D6. It inhibits the growth of the P. falciparum strain LA136 in vitro (IC50 = 9.9 ng/ml).{52377}
Brand:CaymanSKU:30113 - 10 mgAvailable on backorder
Desethylchloroquine is a major active metabolite of chloroquine (Item No. 14194).{52376} Desethylchloroquine is formed when chloroquine undergoes dealkylation, primarily by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP3A4 and to a lesser extent by CYP2D6. It inhibits the growth of the P. falciparum strain LA136 in vitro (IC50 = 9.9 ng/ml).{52377}
Brand:CaymanSKU:30113 - 5 mgAvailable on backorder
Desethylchloroquine-d4 is intended for use as an internal standard for the quantification of desethylchloroquine (Item No. 30113) by GC- or LC-MS. Desethylchloroquine is a major active metabolite of chloroquine (Item No. 14194).{52376} Desethylchloroquine is formed when chloroquine undergoes dealkylation, primarily by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP3A4 and to a lesser extent by CYP2D6. It inhibits the growth of the P. falciparum strain LA136 in vitro (IC50 = 9.9 ng/ml).{52377}
Brand:CaymanSKU:30907 - 1 mgAvailable on backorder
Desethylene ciprofloxacin is a major metabolite of ciprofloxacin (Item No. 14286).{38229} It is also a degradation product of ciprofloxacin that can be created through advanced oxygenation processes as a potential way to remove ciprofloxacin from wastewater.{38230} It is also created during degradation of ciprofloxacin by chlorination.{38231}
Brand:CaymanSKU:22123 -Out of stock
Desethylene ciprofloxacin is a major metabolite of ciprofloxacin (Item No. 14286).{38229} It is also a degradation product of ciprofloxacin that can be created through advanced oxygenation processes as a potential way to remove ciprofloxacin from wastewater.{38230} It is also created during degradation of ciprofloxacin by chlorination.{38231}
Brand:CaymanSKU:22123 -Out of stock
Desethylene ciprofloxacin is a major metabolite of ciprofloxacin (Item No. 14286).{38229} It is also a degradation product of ciprofloxacin that can be created through advanced oxygenation processes as a potential way to remove ciprofloxacin from wastewater.{38230} It is also created during degradation of ciprofloxacin by chlorination.{38231}
Brand:CaymanSKU:22123 -Out of stock
Desidustat is an inhibitor of prolyl hydroxylase (PHD).{52044} It reduces levels of hypoxia-inducible factor-1α (HIF-1α), a transcription factor regulated by PHD enzymes, in rat liver and kidney. Desidustat increases the expression of the red blood cell- and iron transport-related genes Epo, Fpn1, and Hamp in rat liver in a model of anemia induced by peptidoglycan-polysaccharide (PGPS).{52045} It increases plasma levels of erythropoietin in rats by 10.3- to 40-fold when administered at doses of 15 and 30 mg/kg, respectively.{52044} Desidustat (15 and 30 mg/kg) also increases plasma levels of erythropoietin and hemoglobin, as well as the number of circulating red blood cells, in nephrectomized rats in a model of chronic kidney disease-induced anemia. It increases hemoglobin levels and the number of circulating red blood cells in a mouse model of anemia induced by the DNA-crosslinking agent cisplatin (Item No. 13119).
Brand:CaymanSKU:28074 - 10 mgAvailable on backorder
Desidustat is an inhibitor of prolyl hydroxylase (PHD).{52044} It reduces levels of hypoxia-inducible factor-1α (HIF-1α), a transcription factor regulated by PHD enzymes, in rat liver and kidney. Desidustat increases the expression of the red blood cell- and iron transport-related genes Epo, Fpn1, and Hamp in rat liver in a model of anemia induced by peptidoglycan-polysaccharide (PGPS).{52045} It increases plasma levels of erythropoietin in rats by 10.3- to 40-fold when administered at doses of 15 and 30 mg/kg, respectively.{52044} Desidustat (15 and 30 mg/kg) also increases plasma levels of erythropoietin and hemoglobin, as well as the number of circulating red blood cells, in nephrectomized rats in a model of chronic kidney disease-induced anemia. It increases hemoglobin levels and the number of circulating red blood cells in a mouse model of anemia induced by the DNA-crosslinking agent cisplatin (Item No. 13119).
Brand:CaymanSKU:28074 - 100 mgAvailable on backorder
Desidustat is an inhibitor of prolyl hydroxylase (PHD).{52044} It reduces levels of hypoxia-inducible factor-1α (HIF-1α), a transcription factor regulated by PHD enzymes, in rat liver and kidney. Desidustat increases the expression of the red blood cell- and iron transport-related genes Epo, Fpn1, and Hamp in rat liver in a model of anemia induced by peptidoglycan-polysaccharide (PGPS).{52045} It increases plasma levels of erythropoietin in rats by 10.3- to 40-fold when administered at doses of 15 and 30 mg/kg, respectively.{52044} Desidustat (15 and 30 mg/kg) also increases plasma levels of erythropoietin and hemoglobin, as well as the number of circulating red blood cells, in nephrectomized rats in a model of chronic kidney disease-induced anemia. It increases hemoglobin levels and the number of circulating red blood cells in a mouse model of anemia induced by the DNA-crosslinking agent cisplatin (Item No. 13119).
Brand:CaymanSKU:28074 - 50 mgAvailable on backorder
Deslanoside is a cardiac glycoside that has been found in D. lanata.{54296} It induces ventricular tachycardia in anesthetized dogs when administered intravenously at a dose of 0.18 mg/kg.{54297} Formulations containing deslanoside have been used in the treatment of congestive heart failure and cardiac arrythmias.
Brand:CaymanSKU:30872 - 1 mgAvailable on backorder
Deslanoside is a cardiac glycoside that has been found in D. lanata.{54296} It induces ventricular tachycardia in anesthetized dogs when administered intravenously at a dose of 0.18 mg/kg.{54297} Formulations containing deslanoside have been used in the treatment of congestive heart failure and cardiac arrythmias.
Brand:CaymanSKU:30872 - 10 mgAvailable on backorder
Deslanoside is a cardiac glycoside that has been found in D. lanata.{54296} It induces ventricular tachycardia in anesthetized dogs when administered intravenously at a dose of 0.18 mg/kg.{54297} Formulations containing deslanoside have been used in the treatment of congestive heart failure and cardiac arrythmias.
Brand:CaymanSKU:30872 - 25 mgAvailable on backorder
Deslanoside is a cardiac glycoside that has been found in D. lanata.{54296} It induces ventricular tachycardia in anesthetized dogs when administered intravenously at a dose of 0.18 mg/kg.{54297} Formulations containing deslanoside have been used in the treatment of congestive heart failure and cardiac arrythmias.
Brand:CaymanSKU:30872 - 5 mgAvailable on backorder
Desloratadine is the orally active metabolite of the non-sedating antihistamine loratadine (Item No. 15625). It is a tricyclic antagonist of the histamine H1 receptor (Ki = 0.97 nM).{27482,27483} Its use in vivo features long duration of action with minimal sedation.{27483} Although studies indicate that desloratadine antagonizes muscarinic receptors, it has limited effects on peripheral muscarinic receptors in vivo and consequently minimally impacts xerostomia and dry eyes at therapeutic concentrations.{27481}
Brand:CaymanSKU:-Out of stock
Desloratadine is the orally active metabolite of the non-sedating antihistamine loratadine (Item No. 15625). It is a tricyclic antagonist of the histamine H1 receptor (Ki = 0.97 nM).{27482,27483} Its use in vivo features long duration of action with minimal sedation.{27483} Although studies indicate that desloratadine antagonizes muscarinic receptors, it has limited effects on peripheral muscarinic receptors in vivo and consequently minimally impacts xerostomia and dry eyes at therapeutic concentrations.{27481}
Brand:CaymanSKU:-Out of stock
Desloratadine is the orally active metabolite of the non-sedating antihistamine loratadine (Item No. 15625). It is a tricyclic antagonist of the histamine H1 receptor (Ki = 0.97 nM).{27482,27483} Its use in vivo features long duration of action with minimal sedation.{27483} Although studies indicate that desloratadine antagonizes muscarinic receptors, it has limited effects on peripheral muscarinic receptors in vivo and consequently minimally impacts xerostomia and dry eyes at therapeutic concentrations.{27481}
Brand:CaymanSKU:-Out of stock
Desloratadine is the orally active metabolite of the non-sedating antihistamine loratadine (Item No. 15625). It is a tricyclic antagonist of the histamine H1 receptor (Ki = 0.97 nM).{27482,27483} Its use in vivo features long duration of action with minimal sedation.{27483} Although studies indicate that desloratadine antagonizes muscarinic receptors, it has limited effects on peripheral muscarinic receptors in vivo and consequently minimally impacts xerostomia and dry eyes at therapeutic concentrations.{27481}
Brand:CaymanSKU:-Out of stock
Desmethyl erlotinib is a metabolite of erlotinib (Item No. 10483).{40416} Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 µM).{18354,18362} This inhibits tumor growth in human head and neck carcinoma HN5 tumor xenografts in mice with an ED50 value of 9 mg/kg.{18354} Erlotinib also suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 µM) and JAK2 mutant JAK2V617F positive hematopoietic progenitor cells (IC50 = 5 µM), which is associated with polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia.{16061,18355} Formulations containing erlotinib have been used to treat certain forms of cancer, including non-small cell lung cancer.{18351,17857}
Brand:CaymanSKU:23394 - 1 mgAvailable on backorder
Desmethyl erlotinib is a metabolite of erlotinib (Item No. 10483).{40416} Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 µM).{18354,18362} This inhibits tumor growth in human head and neck carcinoma HN5 tumor xenografts in mice with an ED50 value of 9 mg/kg.{18354} Erlotinib also suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 µM) and JAK2 mutant JAK2V617F positive hematopoietic progenitor cells (IC50 = 5 µM), which is associated with polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia.{16061,18355} Formulations containing erlotinib have been used to treat certain forms of cancer, including non-small cell lung cancer.{18351,17857}
Brand:CaymanSKU:23394 - 10 mgAvailable on backorder
Desmethyl erlotinib is a metabolite of erlotinib (Item No. 10483).{40416} Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 µM).{18354,18362} This inhibits tumor growth in human head and neck carcinoma HN5 tumor xenografts in mice with an ED50 value of 9 mg/kg.{18354} Erlotinib also suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 µM) and JAK2 mutant JAK2V617F positive hematopoietic progenitor cells (IC50 = 5 µM), which is associated with polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia.{16061,18355} Formulations containing erlotinib have been used to treat certain forms of cancer, including non-small cell lung cancer.{18351,17857}
Brand:CaymanSKU:23394 - 5 mgAvailable on backorder
Desmethylcitalopram (hydrochloride) (Item No. 15905) is an analytical reference standard that is an active metabolite of citalopram (Item Nos. 23252 | 14572).{37245} This product is intended for research and forensic applications.
Brand:CaymanSKU:-Desmethylcitalopram (hydrochloride) (Item No. 15905) is an analytical reference standard that is an active metabolite of citalopram (Item Nos. 23252 | 14572).{37245} This product is intended for research and forensic applications.
Brand:CaymanSKU:-Desmethylcitalopram-d3 (hydrochloride) (Item No. 15840) is an analytical reference standard intended for use as an internal standard for the quantification of desmethylcitalopram (Item No. 15905) by GC- or LC-MS. Desmethylcitalopram is an active metabolite of citalopram (Item Nos. 23252 | 14572).{37245} This product is intended for research and forensic applications.
Brand:CaymanSKU:-Desmethylcitalopram-d3 (hydrochloride) (Item No. 15840) is an analytical reference standard intended for use as an internal standard for the quantification of desmethylcitalopram (Item No. 15905) by GC- or LC-MS. Desmethylcitalopram is an active metabolite of citalopram (Item Nos. 23252 | 14572).{37245} This product is intended for research and forensic applications.
Brand:CaymanSKU:-Desmethylclotiazepam (Item No. 27838) is an analytical reference standard categorized as a thienodiazepine.{48303} It is an active metabolite of clotiazepam.{48304} This product is intended for research and forensic applications.
Brand:CaymanSKU:27838 - 1 mgAvailable on backorder
Desmethylclotiazepam (Item No. 27838) is an analytical reference standard categorized as a thienodiazepine.{48303} It is an active metabolite of clotiazepam.{48304} This product is intended for research and forensic applications.
Brand:CaymanSKU:27838 - 5 mgAvailable on backorder
Doxepin (Item No. 15888) is a tricyclic antidepressant. Desmethyldoxepin is the primary metabolite of doxepin, produced by metabolism at the liver.{26038,26037} The metabolism of tricyclic antidepressants, including doxepin, is affected by a variety of factors, including age, genetics, and drug-drug interactions.{26039}
Brand:CaymanSKU:-Doxepin (Item No. 15888) is a tricyclic antidepressant. Desmethyldoxepin is the primary metabolite of doxepin, produced by metabolism at the liver.{26038,26037} The metabolism of tricyclic antidepressants, including doxepin, is affected by a variety of factors, including age, genetics, and drug-drug interactions.{26039}
Brand:CaymanSKU:-Doxepin (Item No. 15888) is a tricyclic antidepressant. Desmethyldoxepin is the primary metabolite of doxepin, produced by metabolism at the liver.{26038,26037} The metabolism of tricyclic antidepressants, including doxepin, is affected by a variety of factors, including age, genetics, and drug-drug interactions.{26039}
Brand:CaymanSKU:-Paroxetine (Item No. 14998) is a potent, selective serotonin reuptake inhibitor (Ki = 0.72 nM) that has been used in cases of depression and anxiety disorder.{24255,23626,23628} Desmethylene paroxetine is a major urinary metabolite of paroxetine.{26062,26063} This compound may be used in urine drug testing applications involving paroxetine toxicology or forensic analysis.
Brand:CaymanSKU:-Paroxetine (Item No. 14998) is a potent, selective serotonin reuptake inhibitor (Ki = 0.72 nM) that has been used in cases of depression and anxiety disorder.{24255,23626,23628} Desmethylene paroxetine is a major urinary metabolite of paroxetine.{26062,26063} This compound may be used in urine drug testing applications involving paroxetine toxicology or forensic analysis.
Brand:CaymanSKU:-Paroxetine (Item No. 14998) is a potent, selective serotonin reuptake inhibitor (Ki = 0.72 nM) that has been used in cases of depression and anxiety disorder.{24255,23626,23628} Desmethylene paroxetine is a major urinary metabolite of paroxetine.{26062,26063} This compound may be used in urine drug testing applications involving paroxetine toxicology or forensic analysis.
Brand:CaymanSKU:-Desmopressin is a synthetic version of the endogenous antidiuretic hormone arginine vasopressin (AVP). Compared to AVP, the first amino acid of desmopressin has been deaminated, and the arginine at the eighth position is in the dextrorotatory rather than the levorotatory form. Desmopressin acts as an agonist at human vasopressin V1a, V1b, and V2 receptors with Ki values of 62.4, 5.8, and 23.3 nM, respectively.{28407}
Brand:CaymanSKU:-Available on backorder
Desmopressin is a synthetic version of the endogenous antidiuretic hormone arginine vasopressin (AVP). Compared to AVP, the first amino acid of desmopressin has been deaminated, and the arginine at the eighth position is in the dextrorotatory rather than the levorotatory form. Desmopressin acts as an agonist at human vasopressin V1a, V1b, and V2 receptors with Ki values of 62.4, 5.8, and 23.3 nM, respectively.{28407}
Brand:CaymanSKU:-Available on backorder
Desmopressin is a synthetic version of the endogenous antidiuretic hormone arginine vasopressin (AVP). Compared to AVP, the first amino acid of desmopressin has been deaminated, and the arginine at the eighth position is in the dextrorotatory rather than the levorotatory form. Desmopressin acts as an agonist at human vasopressin V1a, V1b, and V2 receptors with Ki values of 62.4, 5.8, and 23.3 nM, respectively.{28407}
Brand:CaymanSKU:-Available on backorder
Desogestrel is a synthetic progestogen.{41180} It inhibits ovulation and prevents fertilization in rabbits and mice. Desogestrel inhibits rhodamine123 efflux, a measure of P-glycoprotein activity, ex vivo in human lymphocytes and CD8+ T cells in a dose-dependent manner.{41181} Formulations containing desogestrel have been used as oral contraceptives and for the treatment of polycystic ovary syndrome.{41181,41182}
Brand:CaymanSKU:23651 - 10 mgAvailable on backorder
Desogestrel is a synthetic progestogen.{41180} It inhibits ovulation and prevents fertilization in rabbits and mice. Desogestrel inhibits rhodamine123 efflux, a measure of P-glycoprotein activity, ex vivo in human lymphocytes and CD8+ T cells in a dose-dependent manner.{41181} Formulations containing desogestrel have been used as oral contraceptives and for the treatment of polycystic ovary syndrome.{41181,41182}
Brand:CaymanSKU:23651 - 25 mgAvailable on backorder
Desogestrel is a synthetic progestogen.{41180} It inhibits ovulation and prevents fertilization in rabbits and mice. Desogestrel inhibits rhodamine123 efflux, a measure of P-glycoprotein activity, ex vivo in human lymphocytes and CD8+ T cells in a dose-dependent manner.{41181} Formulations containing desogestrel have been used as oral contraceptives and for the treatment of polycystic ovary syndrome.{41181,41182}
Brand:CaymanSKU:23651 - 5 mgAvailable on backorder
Desomorphine is a morphine derivative in which the 6-hydroxyl group and the 7,8 double bond have been reduced. Compared to morphine, it demonstrates similar opioid-like effects with rapid onset, 10 times greater potency, and short duration of action.{26029} This product is intended for forensic and research applications.
Brand:CaymanSKU:-Desonide is a synthetic corticosteroid.{33620} It is a nonfluorinated analog of triamcinolone acetonide (Item No. 18026). Formulations containing desonide are used topically to reduce inflammation in conditions that include allergic reactions and psoriasis.{33620,33619}
Brand:CaymanSKU:21368 -Out of stock
Desonide is a synthetic corticosteroid.{33620} It is a nonfluorinated analog of triamcinolone acetonide (Item No. 18026). Formulations containing desonide are used topically to reduce inflammation in conditions that include allergic reactions and psoriasis.{33620,33619}
Brand:CaymanSKU:21368 -Out of stock
Desonide is a synthetic corticosteroid.{33620} It is a nonfluorinated analog of triamcinolone acetonide (Item No. 18026). Formulations containing desonide are used topically to reduce inflammation in conditions that include allergic reactions and psoriasis.{33620,33619}
Brand:CaymanSKU:21368 -Out of stock
Desonide is a synthetic corticosteroid.{33620} It is a nonfluorinated analog of triamcinolone acetonide (Item No. 18026). Formulations containing desonide are used topically to reduce inflammation in conditions that include allergic reactions and psoriasis.{33620,33619}
Brand:CaymanSKU:21368 -Out of stock
Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces.{49165} It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs = 16, 12.5, and 32 μg/ml, respectively).{49166}
Brand:CaymanSKU:28129 - 2.5 mgAvailable on backorder
Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces.{49165} It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs = 16, 12.5, and 32 μg/ml, respectively).{49166}
Brand:CaymanSKU:28129 - 500 µgAvailable on backorder
Desoximetasone is a glucocorticoid.{39559} In vivo, desoximetasone (0.001-0.1 mg) reverses increases in epidermal cell proliferation induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in SENCAR mice when administered topically. It also reduces TPA-induced expression of IL-6, COX-2, iNOS, and c-Jun mRNA levels in the skin of SENCAR mice, indicating anti-inflammatory action. Formulations containing desoximetasone have been used in the treatment of psoriasis and atopic dermatitis.
Brand:CaymanSKU:23945 - 1 mgAvailable on backorder
Desoximetasone is a glucocorticoid.{39559} In vivo, desoximetasone (0.001-0.1 mg) reverses increases in epidermal cell proliferation induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in SENCAR mice when administered topically. It also reduces TPA-induced expression of IL-6, COX-2, iNOS, and c-Jun mRNA levels in the skin of SENCAR mice, indicating anti-inflammatory action. Formulations containing desoximetasone have been used in the treatment of psoriasis and atopic dermatitis.
Brand:CaymanSKU:23945 - 10 mgAvailable on backorder
Desoximetasone is a glucocorticoid.{39559} In vivo, desoximetasone (0.001-0.1 mg) reverses increases in epidermal cell proliferation induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in SENCAR mice when administered topically. It also reduces TPA-induced expression of IL-6, COX-2, iNOS, and c-Jun mRNA levels in the skin of SENCAR mice, indicating anti-inflammatory action. Formulations containing desoximetasone have been used in the treatment of psoriasis and atopic dermatitis.
Brand:CaymanSKU:23945 - 5 mgAvailable on backorder
Desoximetasone is a glucocorticoid.{39559} In vivo, desoximetasone (0.001-0.1 mg) reverses increases in epidermal cell proliferation induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in SENCAR mice when administered topically. It also reduces TPA-induced expression of IL-6, COX-2, iNOS, and c-Jun mRNA levels in the skin of SENCAR mice, indicating anti-inflammatory action. Formulations containing desoximetasone have been used in the treatment of psoriasis and atopic dermatitis.
Brand:CaymanSKU:23945 - 50 mgAvailable on backorder
Despropionyl meta-chlorofentanyl (Item No. 32506) is an analytical reference standard that is structurally similar to known opioids. This product is intended for research and forensic applications.
Brand:CaymanSKU:32506 - 1 mgAvailable on backorder
Despropionyl meta-chlorofentanyl (Item No. 32506) is an analytical reference standard that is structurally similar to known opioids. This product is intended for research and forensic applications.
Brand:CaymanSKU:32506 - 5 mgAvailable on backorder
Despropionyl meta-Methylfentanyl (Item No. 25744) is an analytical reference standard that is structurally similar to known opioids. This product is intended for research and forensic applications.
Brand:CaymanSKU:25744 - 1 mgAvailable on backorder
Despropionyl meta-Methylfentanyl (Item No. 25744) is an analytical reference standard that is structurally similar to known opioids. This product is intended for research and forensic applications.
Brand:CaymanSKU:25744 - 5 mgAvailable on backorder
Despropionyl ortho-methylfentanyl (Item No. 24279) is an analytical reference standard that is structurally similar to known opioids. It is a presumptive metabolite of ortho-methylfentanyl (Item No. 22634), ortho-methyl furanyl fentanyl (Item Nos. 22806 | 22779), ortho-methyl cyclopropyl fentanyl (Item No. 23043), ortho-methyl acetyl fentanyl (Item No. 23548), ortho-methyl phenyl fentanyl (Item No. 23652), ortho-methyl acrylfentanyl (Item No. 23036), and ortho-methyl methoxyacetyl fentanyl (Item No. 22977). This product is intended for research and forensic applications.
Brand:CaymanSKU:24279 - 1 mgAvailable on backorder
Despropionyl ortho-methylfentanyl (Item No. 24279) is an analytical reference standard that is structurally similar to known opioids. It is a presumptive metabolite of ortho-methylfentanyl (Item No. 22634), ortho-methyl furanyl fentanyl (Item Nos. 22806 | 22779), ortho-methyl cyclopropyl fentanyl (Item No. 23043), ortho-methyl acetyl fentanyl (Item No. 23548), ortho-methyl phenyl fentanyl (Item No. 23652), ortho-methyl acrylfentanyl (Item No. 23036), and ortho-methyl methoxyacetyl fentanyl (Item No. 22977). This product is intended for research and forensic applications.
Brand:CaymanSKU:24279 - 5 mgAvailable on backorder
Despropionyl para-methylfentanyl (Item No. 25745) is an analytical reference standard that is structurally similar to known opioids. This product is intended for research and forensic applications.
Brand:CaymanSKU:25745 - 1 mgAvailable on backorder
Despropionyl para-methylfentanyl (Item No. 25745) is an analytical reference standard that is structurally similar to known opioids. This product is intended for research and forensic applications.
Brand:CaymanSKU:25745 - 5 mgAvailable on backorder
Despropionyl remifentanil (Item No. 9003390) is an analytical reference standard that is structurally similar to known opioids. It is a precursor in the synthesis of remifentanil (Item Nos. 22429 | 19291). This product is intended for research and forensic applications.
Brand:CaymanSKU:9003390 - 1 mgAvailable on backorder
Despropionyl remifentanil (Item No. 9003390) is an analytical reference standard that is structurally similar to known opioids. It is a precursor in the synthesis of remifentanil (Item Nos. 22429 | 19291). This product is intended for research and forensic applications.
Brand:CaymanSKU:9003390 - 5 mgAvailable on backorder
Destruxin A is a cyclic hexadepsipeptide mycotoxin first isolated from O. destructor and commonly found in entomopathogenic fungi.{31992} It has insecticidal activity by affecting diverse pathways, including those related to immune response, calcium signaling, and development.{31990,31991}
Brand:CaymanSKU:20428 -Available on backorder