Cayman

Showing 1651–1800 of 45550 results

  • 1-Lauroyl-rac-glycerol is a monoacylglycerol that contains lauric acid (Item No. 10006626) at the sn-1 position. It is active against pneumococci, group A streptococci, β-hemolytic non-group A streptococci, corynebacteria, N. asteroides, micrococci, S. aureus, S. epidermidis, and C. albicans (MICs = 0.045-0.09 μmol/ml).{53096} It is also active against a panel of 16 fungi when used at a concentration of 0.1% in growth media.{53097} Dietary administration of 1-lauroyl-rac-glycerol (2% w/w) reduces S. mutans colony forming units (CFUs) on tooth surfaces and severity of sucrose-induced dental caries in rats.{53098}  

     

    Brand:
    Cayman
    SKU:28170 - 1 g

    Available on backorder

  • 1-Lauroyl-rac-glycerol is a monoacylglycerol that contains lauric acid (Item No. 10006626) at the sn-1 position. It is active against pneumococci, group A streptococci, β-hemolytic non-group A streptococci, corynebacteria, N. asteroides, micrococci, S. aureus, S. epidermidis, and C. albicans (MICs = 0.045-0.09 μmol/ml).{53096} It is also active against a panel of 16 fungi when used at a concentration of 0.1% in growth media.{53097} Dietary administration of 1-lauroyl-rac-glycerol (2% w/w) reduces S. mutans colony forming units (CFUs) on tooth surfaces and severity of sucrose-induced dental caries in rats.{53098}  

     

    Brand:
    Cayman
    SKU:28170 - 500 mg

    Available on backorder

  • Platelet-activating factor (PAF) is a biologically active phospholipid synthesized by a variety of stimulated cells that acts as a mediator of platelet aggregation, inflammation, and allergy.{939,11753} PAF is converted to the biologically inactive lyso-PAF by the enzyme PAF acetylhydrolase (PAF-AH). Recently, plasma PAF-AH has been linked to atherosclerosis and may be a positive risk factor for coronary heart disease in humans.{11455} 1-Linoleoyl glycerol (1-LG) is a fatty acid glycerol that has been isolated from S. chinensis roots. It inhibits PAF-AH with an IC50 of 45 µM.{14173} 1-LG has potential application in cholesterol lowering and antiatherogenic activity.  

     

    Brand:
    Cayman
    SKU:10008869 - 1 mg

    Available on backorder

  • Platelet-activating factor (PAF) is a biologically active phospholipid synthesized by a variety of stimulated cells that acts as a mediator of platelet aggregation, inflammation, and allergy.{939,11753} PAF is converted to the biologically inactive lyso-PAF by the enzyme PAF acetylhydrolase (PAF-AH). Recently, plasma PAF-AH has been linked to atherosclerosis and may be a positive risk factor for coronary heart disease in humans.{11455} 1-Linoleoyl glycerol (1-LG) is a fatty acid glycerol that has been isolated from S. chinensis roots. It inhibits PAF-AH with an IC50 of 45 µM.{14173} 1-LG has potential application in cholesterol lowering and antiatherogenic activity.  

     

    Brand:
    Cayman
    SKU:10008869 - 10 mg

    Available on backorder

  • Platelet-activating factor (PAF) is a biologically active phospholipid synthesized by a variety of stimulated cells that acts as a mediator of platelet aggregation, inflammation, and allergy.{939,11753} PAF is converted to the biologically inactive lyso-PAF by the enzyme PAF acetylhydrolase (PAF-AH). Recently, plasma PAF-AH has been linked to atherosclerosis and may be a positive risk factor for coronary heart disease in humans.{11455} 1-Linoleoyl glycerol (1-LG) is a fatty acid glycerol that has been isolated from S. chinensis roots. It inhibits PAF-AH with an IC50 of 45 µM.{14173} 1-LG has potential application in cholesterol lowering and antiatherogenic activity.  

     

    Brand:
    Cayman
    SKU:10008869 - 25 mg

    Available on backorder

  • Platelet-activating factor (PAF) is a biologically active phospholipid synthesized by a variety of stimulated cells that acts as a mediator of platelet aggregation, inflammation, and allergy.{939,11753} PAF is converted to the biologically inactive lyso-PAF by the enzyme PAF acetylhydrolase (PAF-AH). Recently, plasma PAF-AH has been linked to atherosclerosis and may be a positive risk factor for coronary heart disease in humans.{11455} 1-Linoleoyl glycerol (1-LG) is a fatty acid glycerol that has been isolated from S. chinensis roots. It inhibits PAF-AH with an IC50 of 45 µM.{14173} 1-LG has potential application in cholesterol lowering and antiatherogenic activity.  

     

    Brand:
    Cayman
    SKU:10008869 - 5 mg

    Available on backorder

  • 1-Linoleoyl-2-hydroxy-sn-glycero-3-PC (LGPC) is a lysophospholipid containing linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1 position that has been found in mouse heart, lung, liver, spleen, kidney, plasma, and serum.{54356} Serum levels of LGPC decrease with increasing insulin resistance and dysglycemia in humans.{54357}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Linoleoyl-2-hydroxy-sn-glycero-3-PC (LGPC) is a lysophospholipid containing linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1 position that has been found in mouse heart, lung, liver, spleen, kidney, plasma, and serum.{54356} Serum levels of LGPC decrease with increasing insulin resistance and dysglycemia in humans.{54357}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Linoleoyl-2-hydroxy-sn-glycero-3-PC (LGPC) is a lysophospholipid containing linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1 position that has been found in mouse heart, lung, liver, spleen, kidney, plasma, and serum.{54356} Serum levels of LGPC decrease with increasing insulin resistance and dysglycemia in humans.{54357}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Linoleoyl-3-palmitoyl-rac-glycerol is a diacylglycerol that contains linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1 position and palmitic acid (Item No. 10006627) at the sn-3 position. It has been found in wheat bran extracts and dry-cured, but not raw, Iberian ham.{51025,42670}  

     

    Brand:
    Cayman
    SKU:28176 - 1 mg

    Available on backorder

  • 1-Linoleoyl-3-palmitoyl-rac-glycerol is a diacylglycerol that contains linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1 position and palmitic acid (Item No. 10006627) at the sn-3 position. It has been found in wheat bran extracts and dry-cured, but not raw, Iberian ham.{51025,42670}  

     

    Brand:
    Cayman
    SKU:28176 - 10 mg

    Available on backorder

  • 1-Linoleoyl-3-palmitoyl-rac-glycerol is a diacylglycerol that contains linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1 position and palmitic acid (Item No. 10006627) at the sn-3 position. It has been found in wheat bran extracts and dry-cured, but not raw, Iberian ham.{51025,42670}  

     

    Brand:
    Cayman
    SKU:28176 - 25 mg

    Available on backorder

  • 1-Linoleoyl-3-palmitoyl-rac-glycerol is a diacylglycerol that contains linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1 position and palmitic acid (Item No. 10006627) at the sn-3 position. It has been found in wheat bran extracts and dry-cured, but not raw, Iberian ham.{51025,42670}  

     

    Brand:
    Cayman
    SKU:28176 - 5 mg

    Available on backorder

  • 1-Linoleoyl-3-α-linolenoyl-rac-glycerol is a diacylglycerol that contains linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1 position and α-linolenic acid (Item Nos. 90210 | 21910) at the sn-3 position. It has been found in olive oil subjected to lipase-catalyzed glycerolysis with immobilized lipase B from C. antarctica.{45452}  

     

    Brand:
    Cayman
    SKU:26829 - 10 mg

    Available on backorder

  • 1-Linoleoyl-3-α-linolenoyl-rac-glycerol is a diacylglycerol that contains linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1 position and α-linolenic acid (Item Nos. 90210 | 21910) at the sn-3 position. It has been found in olive oil subjected to lipase-catalyzed glycerolysis with immobilized lipase B from C. antarctica.{45452}  

     

    Brand:
    Cayman
    SKU:26829 - 25 mg

    Available on backorder

  • 1-Linoleoyl-3-α-linolenoyl-rac-glycerol is a diacylglycerol that contains linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1 position and α-linolenic acid (Item Nos. 90210 | 21910) at the sn-3 position. It has been found in olive oil subjected to lipase-catalyzed glycerolysis with immobilized lipase B from C. antarctica.{45452}  

     

    Brand:
    Cayman
    SKU:26829 - 5 mg

    Available on backorder

  • 1-methoxy-5-Methylphenazinium (methyl sulfate) is a photochemically stable mediator of electron transport between NADPH and various electron acceptors such as tetrazolium dyes.{33380} It can be used to visualize NAD-linked dehydrogenase activities.  

     

    Brand:
    Cayman
    SKU:21258 -

    Out of stock

  • 1-methoxy-5-Methylphenazinium (methyl sulfate) is a photochemically stable mediator of electron transport between NADPH and various electron acceptors such as tetrazolium dyes.{33380} It can be used to visualize NAD-linked dehydrogenase activities.  

     

    Brand:
    Cayman
    SKU:21258 -

    Out of stock

  • 1-methoxy-5-Methylphenazinium (methyl sulfate) is a photochemically stable mediator of electron transport between NADPH and various electron acceptors such as tetrazolium dyes.{33380} It can be used to visualize NAD-linked dehydrogenase activities.  

     

    Brand:
    Cayman
    SKU:21258 -

    Out of stock

  • 1-methoxy-5-Methylphenazinium (methyl sulfate) is a photochemically stable mediator of electron transport between NADPH and various electron acceptors such as tetrazolium dyes.{33380} It can be used to visualize NAD-linked dehydrogenase activities.  

     

    Brand:
    Cayman
    SKU:21258 -

    Out of stock

  • 1-Methyl-1,4-dihydronicotinamide is a derivative of nicotinamide (Item No. 11127).{38407} It inhibits β-elimination activity of human serine racemase (hSR; IC50 = 177 μM) through binding to an allosteric and hydrophobic site on the enzyme.  

     

    Brand:
    Cayman
    SKU:23226 - 10 mg

    Available on backorder

  • 1-Methyl-1,4-dihydronicotinamide is a derivative of nicotinamide (Item No. 11127).{38407} It inhibits β-elimination activity of human serine racemase (hSR; IC50 = 177 μM) through binding to an allosteric and hydrophobic site on the enzyme.  

     

    Brand:
    Cayman
    SKU:23226 - 25 mg

    Available on backorder

  • 1-Methyl-1,4-dihydronicotinamide is a derivative of nicotinamide (Item No. 11127).{38407} It inhibits β-elimination activity of human serine racemase (hSR; IC50 = 177 μM) through binding to an allosteric and hydrophobic site on the enzyme.  

     

    Brand:
    Cayman
    SKU:23226 - 5 mg

    Available on backorder

  • 1-Methyl-1,4-dihydronicotinamide is a derivative of nicotinamide (Item No. 11127).{38407} It inhibits β-elimination activity of human serine racemase (hSR; IC50 = 177 μM) through binding to an allosteric and hydrophobic site on the enzyme.  

     

    Brand:
    Cayman
    SKU:23226 - 50 mg

    Available on backorder

  • 1-Methyl-3-BZP (Item No. 24418) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:24418 - 1 mg

    Available on backorder

  • 1-Methyl-3-BZP (Item No. 24418) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.  

     

    Brand:
    Cayman
    SKU:24418 - 5 mg

    Available on backorder

  • 1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine.{30531,30530} Urinary levels of MIMA are commonly measured to evaluate histamine secretion, particularly in the context of systemic mastocytosis.{30533,30534,30532}  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • 1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine.{30531,30530} Urinary levels of MIMA are commonly measured to evaluate histamine secretion, particularly in the context of systemic mastocytosis.{30533,30534,30532}  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • 1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine.{30531,30530} Urinary levels of MIMA are commonly measured to evaluate histamine secretion, particularly in the context of systemic mastocytosis.{30533,30534,30532}  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • 1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine.{30531,30530} Urinary levels of MIMA are commonly measured to evaluate histamine secretion, particularly in the context of systemic mastocytosis.{30533,30534,30532}  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • Indoleamine 2,3-dioxygenase (IDO) metabolizes tryptophan to kynurenine, leading to the production of NAD+ via the kynurenine pathway. The overexpression of IDO in tumors and tumor-draining lymph nodes induces immune tolerance and enhances tumor growth in vivo.{26962,26961} 1-methyl-D-Tryptophan is an inhibitor of IDO (IC50 = 7 µM) that is effective in vivo.{26963,26959} In mice, 1-methyl-D-tryptophan prevents T-cell anergy triggered by dendritic cells overexpressing IDO.{26959} It augments the antitumor and antiviral immunoresponse of CD8+ T-cells and reduces tumor volume in mice with xenografts overexpressing IDO.{26962,26961} 1-methyl-D-Tryptophan, in combination with chemotherapy, causes regression of tumors and prolongs survival.{26962,26960} Surprisingly, 1-methyl-D-tryptophan induces the expression of IDO in human ovarian carcinoma SKOV3 cells in culture.{26960}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • Indoleamine 2,3-dioxygenase (IDO) metabolizes tryptophan to kynurenine, leading to the production of NAD+ via the kynurenine pathway. The overexpression of IDO in tumors and tumor-draining lymph nodes induces immune tolerance and enhances tumor growth in vivo.{26962,26961} 1-methyl-D-Tryptophan is an inhibitor of IDO (IC50 = 7 µM) that is effective in vivo.{26963,26959} In mice, 1-methyl-D-tryptophan prevents T-cell anergy triggered by dendritic cells overexpressing IDO.{26959} It augments the antitumor and antiviral immunoresponse of CD8+ T-cells and reduces tumor volume in mice with xenografts overexpressing IDO.{26962,26961} 1-methyl-D-Tryptophan, in combination with chemotherapy, causes regression of tumors and prolongs survival.{26962,26960} Surprisingly, 1-methyl-D-tryptophan induces the expression of IDO in human ovarian carcinoma SKOV3 cells in culture.{26960}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • Indoleamine 2,3-dioxygenase (IDO) metabolizes tryptophan to kynurenine, leading to the production of NAD+ via the kynurenine pathway. The overexpression of IDO in tumors and tumor-draining lymph nodes induces immune tolerance and enhances tumor growth in vivo.{26962,26961} 1-methyl-D-Tryptophan is an inhibitor of IDO (IC50 = 7 µM) that is effective in vivo.{26963,26959} In mice, 1-methyl-D-tryptophan prevents T-cell anergy triggered by dendritic cells overexpressing IDO.{26959} It augments the antitumor and antiviral immunoresponse of CD8+ T-cells and reduces tumor volume in mice with xenografts overexpressing IDO.{26962,26961} 1-methyl-D-Tryptophan, in combination with chemotherapy, causes regression of tumors and prolongs survival.{26962,26960} Surprisingly, 1-methyl-D-tryptophan induces the expression of IDO in human ovarian carcinoma SKOV3 cells in culture.{26960}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • Indoleamine 2,3-dioxygenase (IDO) metabolizes tryptophan to kynurenine, leading to the production of NAD+ via the kynurenine pathway. The overexpression of IDO in tumors and tumor-draining lymph nodes induces immune tolerance and enhances tumor growth in vivo.{26962,26961} 1-methyl-D-Tryptophan is an inhibitor of IDO (IC50 = 7 µM) that is effective in vivo.{26963,26959} In mice, 1-methyl-D-tryptophan prevents T-cell anergy triggered by dendritic cells overexpressing IDO.{26959} It augments the antitumor and antiviral immunoresponse of CD8+ T-cells and reduces tumor volume in mice with xenografts overexpressing IDO.{26962,26961} 1-methyl-D-Tryptophan, in combination with chemotherapy, causes regression of tumors and prolongs survival.{26962,26960} Surprisingly, 1-methyl-D-tryptophan induces the expression of IDO in human ovarian carcinoma SKOV3 cells in culture.{26960}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases.{27864,27867,27862} The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection.{17048,27865,27863} It can also be monitored in serum.{27868} Urinary levels of 1-methyladenosine also increase during active rheumatoid arthritis.{27866}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases.{27864,27867,27862} The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection.{17048,27865,27863} It can also be monitored in serum.{27868} Urinary levels of 1-methyladenosine also increase during active rheumatoid arthritis.{27866}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases.{27864,27867,27862} The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection.{17048,27865,27863} It can also be monitored in serum.{27868} Urinary levels of 1-methyladenosine also increase during active rheumatoid arthritis.{27866}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases.{27864,27867,27862} The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection.{17048,27865,27863} It can also be monitored in serum.{27868} Urinary levels of 1-methyladenosine also increase during active rheumatoid arthritis.{27866}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Methylhistamine is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism.{30531} It has been used as a biomarker of histaminergic system activity in the brains of Alzheimer’s disease patients as well as those with hypersomnia and other neurological conditions.{31523,31522}  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • 1-Methylhistamine is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism.{30531} It has been used as a biomarker of histaminergic system activity in the brains of Alzheimer’s disease patients as well as those with hypersomnia and other neurological conditions.{31523,31522}  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • 1-Methylhistamine is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism.{30531} It has been used as a biomarker of histaminergic system activity in the brains of Alzheimer’s disease patients as well as those with hypersomnia and other neurological conditions.{31523,31522}  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • 1-Methylhistamine is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism.{30531} It has been used as a biomarker of histaminergic system activity in the brains of Alzheimer’s disease patients as well as those with hypersomnia and other neurological conditions.{31523,31522}  

     

    Brand:
    Cayman
    SKU:-

    Available on backorder

  • Nicotinamide is a precursor of NAD (Item No. 16077) and NADP (Item No. 10004675), which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide N-methyltransferase (NNMT; Item No. 15138).{24617} It demonstrates antithrombotic and anti-inflammatory properties through direct action on the endothelium by a mechanism involving the prostacyclin pathway and by improving nitric oxide bioavailability.{24618,27798} Aggressive cancer cell lines are reported to have higher levels of MNA due to increased NNMT-directed transfer of methyl groups from S-adenosyl-L-methionine to nicotinamide, implicating a role for MNA in cancer cell metabolism.{24772,24614}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • Nicotinamide is a precursor of NAD (Item No. 16077) and NADP (Item No. 10004675), which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide N-methyltransferase (NNMT; Item No. 15138).{24617} It demonstrates antithrombotic and anti-inflammatory properties through direct action on the endothelium by a mechanism involving the prostacyclin pathway and by improving nitric oxide bioavailability.{24618,27798} Aggressive cancer cell lines are reported to have higher levels of MNA due to increased NNMT-directed transfer of methyl groups from S-adenosyl-L-methionine to nicotinamide, implicating a role for MNA in cancer cell metabolism.{24772,24614}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • Nicotinamide is a precursor of NAD (Item No. 16077) and NADP (Item No. 10004675), which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide N-methyltransferase (NNMT; Item No. 15138).{24617} It demonstrates antithrombotic and anti-inflammatory properties through direct action on the endothelium by a mechanism involving the prostacyclin pathway and by improving nitric oxide bioavailability.{24618,27798} Aggressive cancer cell lines are reported to have higher levels of MNA due to increased NNMT-directed transfer of methyl groups from S-adenosyl-L-methionine to nicotinamide, implicating a role for MNA in cancer cell metabolism.{24772,24614}  

     

    Brand:
    Cayman
    SKU:-

    Out of stock

  • 1-Myristoyl-2-hydroxy-sn-glycero-3-PC is a saturated 14:0 lysophosphatidylcholine that consists of one chain of myristic acid (Item No. 13351) at the sn-1 position. It is formed in plasma by lecithin:cholesterol acyltransferase (LCAT) and has a role in lipid signaling by acting on lysophospholipid receptors.{17610}  

     

    Brand:
    Cayman
    SKU:20958 -

    Out of stock

  • 1-Myristoyl-2-hydroxy-sn-glycero-3-PC is a saturated 14:0 lysophosphatidylcholine that consists of one chain of myristic acid (Item No. 13351) at the sn-1 position. It is formed in plasma by lecithin:cholesterol acyltransferase (LCAT) and has a role in lipid signaling by acting on lysophospholipid receptors.{17610}  

     

    Brand:
    Cayman
    SKU:20958 -

    Out of stock

  • 1-Myristoyl-2-hydroxy-sn-glycero-3-PC is a saturated 14:0 lysophosphatidylcholine that consists of one chain of myristic acid (Item No. 13351) at the sn-1 position. It is formed in plasma by lecithin:cholesterol acyltransferase (LCAT) and has a role in lipid signaling by acting on lysophospholipid receptors.{17610}  

     

    Brand:
    Cayman
    SKU:20958 -

    Out of stock

  • 1-Myristoyl-2-hydroxy-sn-glycero-3-PC is a saturated 14:0 lysophosphatidylcholine that consists of one chain of myristic acid (Item No. 13351) at the sn-1 position. It is formed in plasma by lecithin:cholesterol acyltransferase (LCAT) and has a role in lipid signaling by acting on lysophospholipid receptors.{17610}  

     

    Brand:
    Cayman
    SKU:20958 -

    Out of stock

  • 1-Myristoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid.{48105} It induces transient increases in intracellular calcium in PC12 cells.{36852} Serum levels of 1-myristoyl-2-hydroxy-sn-glycero-3-PE are elevated in patients with malignant breast cancer compared to healthy controls.{48105}  

     

    Brand:
    Cayman
    SKU:25591 - 25 mg

    Available on backorder

  • 1-Myristoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid.{48105} It induces transient increases in intracellular calcium in PC12 cells.{36852} Serum levels of 1-myristoyl-2-hydroxy-sn-glycero-3-PE are elevated in patients with malignant breast cancer compared to healthy controls.{48105}  

     

    Brand:
    Cayman
    SKU:25591 - 5 mg

    Available on backorder

  • 1-Myristoyl-2-hydroxy-sn-glycero-3-PG is a lysophospholipid containing myristic acid (14:0) at the sn-1 position. It has been used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.{33498}  

     

    Brand:
    Cayman
    SKU:25587 - 1 g

    Available on backorder

  • 1-Myristoyl-2-hydroxy-sn-glycero-3-PG is a lysophospholipid containing myristic acid (14:0) at the sn-1 position. It has been used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.{33498}  

     

    Brand:
    Cayman
    SKU:25587 - 100 mg

    Available on backorder

  • 1-Myristoyl-2-hydroxy-sn-glycero-3-PG is a lysophospholipid containing myristic acid (14:0) at the sn-1 position. It has been used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.{33498}  

     

    Brand:
    Cayman
    SKU:25587 - 250 mg

    Available on backorder

  • 1-Myristoyl-2-hydroxy-sn-glycero-3-PG is a lysophospholipid containing myristic acid (14:0) at the sn-1 position. It has been used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.{33498}  

     

    Brand:
    Cayman
    SKU:25587 - 500 mg

    Available on backorder

  • 1-Myristoyl-2-lauroyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and lauric acid (Item No. 10006626) at the sn-2 position.  

     

    Brand:
    Cayman
    SKU:26880 - 1 mg

    Available on backorder

  • 1-Myristoyl-2-lauroyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and lauric acid (Item No. 10006626) at the sn-2 position.  

     

    Brand:
    Cayman
    SKU:26880 - 10 mg

    Available on backorder

  • 1-Myristoyl-2-lauroyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and lauric acid (Item No. 10006626) at the sn-2 position.  

     

    Brand:
    Cayman
    SKU:26880 - 5 mg

    Available on backorder

  • 1-Myristoyl-2-linoleoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains myristic acid (Item No. 13351), linoleic acid (Item Nos. 90150 | 90150.1 | 21909), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in mature human milk, infant formula fats, and butterfat.{48194,46189}  

     

    Brand:
    Cayman
    SKU:28561 - 1 mg

    Available on backorder

  • 1-Myristoyl-2-linoleoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains myristic acid (Item No. 13351), linoleic acid (Item Nos. 90150 | 90150.1 | 21909), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in mature human milk, infant formula fats, and butterfat.{48194,46189}  

     

    Brand:
    Cayman
    SKU:28561 - 10 mg

    Available on backorder

  • 1-Myristoyl-2-linoleoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains myristic acid (Item No. 13351), linoleic acid (Item Nos. 90150 | 90150.1 | 21909), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in mature human milk, infant formula fats, and butterfat.{48194,46189}  

     

    Brand:
    Cayman
    SKU:28561 - 5 mg

    Available on backorder

  • 1-Myristoyl-2-linoleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains myristic acid (Item No. 13351), linoleic acid (Item Nos. 90150 | 90150.1 | 21909), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in palm and vegetable oils.{53094,53095}  

     

    Brand:
    Cayman
    SKU:28560 - 1 mg

    Available on backorder

  • 1-Myristoyl-2-linoleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains myristic acid (Item No. 13351), linoleic acid (Item Nos. 90150 | 90150.1 | 21909), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in palm and vegetable oils.{53094,53095}  

     

    Brand:
    Cayman
    SKU:28560 - 10 mg

    Available on backorder

  • 1-Myristoyl-2-linoleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains myristic acid (Item No. 13351), linoleic acid (Item Nos. 90150 | 90150.1 | 21909), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in palm and vegetable oils.{53094,53095}  

     

    Brand:
    Cayman
    SKU:28560 - 5 mg

    Available on backorder

  • 1-Myristoyl-2-oleoyl-3-butyryl-rac-glycerol is a triacylglycerol containing myristic acid (Item No. 13351), oleic acid (Item Nos. 90260 | 24659), and butyric acid (Item No. 13121) in the sn-1, sn-2, and sn-3 positions, respectively. It has been found in human breast milk.{49050}  

     

    Brand:
    Cayman
    SKU:26823 - 1 mg

    Available on backorder

  • 1-Myristoyl-2-oleoyl-3-butyryl-rac-glycerol is a triacylglycerol containing myristic acid (Item No. 13351), oleic acid (Item Nos. 90260 | 24659), and butyric acid (Item No. 13121) in the sn-1, sn-2, and sn-3 positions, respectively. It has been found in human breast milk.{49050}  

     

    Brand:
    Cayman
    SKU:26823 - 10 mg

    Available on backorder

  • 1-Myristoyl-2-oleoyl-3-butyryl-rac-glycerol is a triacylglycerol containing myristic acid (Item No. 13351), oleic acid (Item Nos. 90260 | 24659), and butyric acid (Item No. 13121) in the sn-1, sn-2, and sn-3 positions, respectively. It has been found in human breast milk.{49050}  

     

    Brand:
    Cayman
    SKU:26823 - 5 mg

    Available on backorder

  • 1-Myristoyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains myristic acid (Item No. 13351), oleic acid (Item Nos. 90260 | 24659), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in butterfat and the fat body of male B. hortorum bumblebees.{46825,42664} 1-Myristoyl-2-oleoyl-3-palmitoyl-rac-glycerol has also been found as a minor triacylglycerol preserved in the subcutaneous fat of the 5,300-year-old Iceman mummy.{46826}  

     

    Brand:
    Cayman
    SKU:29233 - 10 mg

    Available on backorder

  • 1-Myristoyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains myristic acid (Item No. 13351), oleic acid (Item Nos. 90260 | 24659), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in butterfat and the fat body of male B. hortorum bumblebees.{46825,42664} 1-Myristoyl-2-oleoyl-3-palmitoyl-rac-glycerol has also been found as a minor triacylglycerol preserved in the subcutaneous fat of the 5,300-year-old Iceman mummy.{46826}  

     

    Brand:
    Cayman
    SKU:29233 - 25 mg

    Available on backorder

  • 1-Myristoyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains myristic acid (Item No. 13351), oleic acid (Item Nos. 90260 | 24659), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in butterfat and the fat body of male B. hortorum bumblebees.{46825,42664} 1-Myristoyl-2-oleoyl-3-palmitoyl-rac-glycerol has also been found as a minor triacylglycerol preserved in the subcutaneous fat of the 5,300-year-old Iceman mummy.{46826}  

     

    Brand:
    Cayman
    SKU:29233 - 5 mg

    Available on backorder

  • 1-Myristoyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains myristic acid (Item No. 13351), oleic acid (Item Nos. 90260 | 24659), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in butterfat and the fat body of male B. hortorum bumblebees.{46825,42664} 1-Myristoyl-2-oleoyl-3-palmitoyl-rac-glycerol has also been found as a minor triacylglycerol preserved in the subcutaneous fat of the 5,300-year-old Iceman mummy.{46826}  

     

    Brand:
    Cayman
    SKU:29233 - 50 mg

    Available on backorder

  • 1-Myristoyl-2-palmitoyl-3-butyryl-rac-glycerol is a triacylglycerol containing myristic acid (Item No. 13351), palmitic acid (Item No. 10006627), and butyric acid (Item No. 13121) at the sn-1, sn-2, and sn-3 positions, respectively. It has been detected in human breast milk.{49049}  

     

    Brand:
    Cayman
    SKU:26821 - 1 mg

    Available on backorder

  • 1-Myristoyl-2-palmitoyl-3-butyryl-rac-glycerol is a triacylglycerol containing myristic acid (Item No. 13351), palmitic acid (Item No. 10006627), and butyric acid (Item No. 13121) at the sn-1, sn-2, and sn-3 positions, respectively. It has been detected in human breast milk.{49049}  

     

    Brand:
    Cayman
    SKU:26821 - 10 mg

    Available on backorder

  • 1-Myristoyl-2-palmitoyl-3-butyryl-rac-glycerol is a triacylglycerol containing myristic acid (Item No. 13351), palmitic acid (Item No. 10006627), and butyric acid (Item No. 13121) at the sn-1, sn-2, and sn-3 positions, respectively. It has been detected in human breast milk.{49049}  

     

    Brand:
    Cayman
    SKU:26821 - 5 mg

    Available on backorder

  • 1-Myristoyl-3-butyryl-rac-glycerol is a diacylglycerol containing myristic acid (Item No. 13351) at the sn-1 position and butyric acid (Item No. 13121) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26794 - 10 mg

    Available on backorder

  • 1-Myristoyl-3-butyryl-rac-glycerol is a diacylglycerol containing myristic acid (Item No. 13351) at the sn-1 position and butyric acid (Item No. 13121) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26794 - 25 mg

    Available on backorder

  • 1-Myristoyl-3-butyryl-rac-glycerol is a diacylglycerol containing myristic acid (Item No. 13351) at the sn-1 position and butyric acid (Item No. 13121) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26794 - 5 mg

    Available on backorder

  • 1-Myristoyl-3-butyryl-rac-glycerol is a diacylglycerol containing myristic acid (Item No. 13351) at the sn-1 position and butyric acid (Item No. 13121) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26794 - 50 mg

    Available on backorder

  • 1-Myristoyl-3-docosanoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and docosanoic acid (Item No. 9000338) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26999 - 1 mg

    Available on backorder

  • 1-Myristoyl-3-docosanoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and docosanoic acid (Item No. 9000338) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26999 - 10 mg

    Available on backorder

  • 1-Myristoyl-3-docosanoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and docosanoic acid (Item No. 9000338) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26999 - 5 mg

    Available on backorder

  • 1-Myristoyl-3-elaidoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) and elaidic acid (Item No. 90250) at the sn-1 and sn-3 positions, respectively.  

     

    Brand:
    Cayman
    SKU:27289 - 1 mg

    Available on backorder

  • 1-Myristoyl-3-elaidoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) and elaidic acid (Item No. 90250) at the sn-1 and sn-3 positions, respectively.  

     

    Brand:
    Cayman
    SKU:27289 - 10 mg

    Available on backorder

  • 1-Myristoyl-3-elaidoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) and elaidic acid (Item No. 90250) at the sn-1 and sn-3 positions, respectively.  

     

    Brand:
    Cayman
    SKU:27289 - 5 mg

    Available on backorder

  • 1-Myristoyl-3-oleoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and oleic acid (Item Nos. 90260 | 24659) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26886 - 10 mg

    Available on backorder

  • 1-Myristoyl-3-oleoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and oleic acid (Item Nos. 90260 | 24659) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26886 - 25 mg

    Available on backorder

  • 1-Myristoyl-3-oleoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and oleic acid (Item Nos. 90260 | 24659) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26886 - 5 mg

    Available on backorder

  • 1-Myristoyl-3-oleoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and oleic acid (Item Nos. 90260 | 24659) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26886 - 50 mg

    Available on backorder

  • 1-Myristoyl-3-palmitoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and palmitic acid (Item No. 10006627) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26873 - 1 mg

    Available on backorder

  • 1-Myristoyl-3-palmitoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and palmitic acid (Item No. 10006627) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26873 - 10 mg

    Available on backorder

  • 1-Myristoyl-3-palmitoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and palmitic acid (Item No. 10006627) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26873 - 25 mg

    Available on backorder

  • 1-Myristoyl-3-palmitoyl-rac-glycerol is a diacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position and palmitic acid (Item No. 10006627) at the sn-3 position.  

     

    Brand:
    Cayman
    SKU:26873 - 5 mg

    Available on backorder

  • 1-Myristoyl-rac-glycerol is a monoacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position. It is active against H. pylori with a 50% bactericidal concentration (BC50) value of 0.3 mM.{45619} 1-Myristoyl-rac-glycerol is cytotoxic to A498, PaCa-2, and PC3 cancer cells (EC50s = 3.58, 1.87, and 8.84 µg/ml, respectively).{45620} It has been found in saw palmetto berries.  

     

    Brand:
    Cayman
    SKU:28173 - 100 mg

    Available on backorder

  • 1-Myristoyl-rac-glycerol is a monoacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position. It is active against H. pylori with a 50% bactericidal concentration (BC50) value of 0.3 mM.{45619} 1-Myristoyl-rac-glycerol is cytotoxic to A498, PaCa-2, and PC3 cancer cells (EC50s = 3.58, 1.87, and 8.84 µg/ml, respectively).{45620} It has been found in saw palmetto berries.  

     

    Brand:
    Cayman
    SKU:28173 - 250 mg

    Available on backorder

  • 1-Myristoyl-rac-glycerol is a monoacylglycerol that contains myristic acid (Item No. 13351) at the sn-1 position. It is active against H. pylori with a 50% bactericidal concentration (BC50) value of 0.3 mM.{45619} 1-Myristoyl-rac-glycerol is cytotoxic to A498, PaCa-2, and PC3 cancer cells (EC50s = 3.58, 1.87, and 8.84 µg/ml, respectively).{45620} It has been found in saw palmetto berries.  

     

    Brand:
    Cayman
    SKU:28173 - 500 mg

    Available on backorder

  • 1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become ‘analog sensitive’ (as), as compared to the wild-type kinase. 1-NA-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 1.5 nM versus 1.0 μM, respectively).{17286} The homologous mutation in other kinases generated similar analog sensitivity (e.g., IC50 = 1.5 nM for c-Fyn-as1 versus 0.6 μM for c-Fyn; 7.0 nM for c-Abl-as2 versus 0.6 μM for c-Abl; 15 nM for Cdk2-as1 versus 18 μM for Cdk2).{17287} This approach has been used to elucidate functions of several kinases in both mammalian and yeast systems.{17287,20028,20029}  

     

    Brand:
    Cayman
    SKU:10954 - 1 mg

    Available on backorder

  • 1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become ‘analog sensitive’ (as), as compared to the wild-type kinase. 1-NA-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 1.5 nM versus 1.0 μM, respectively).{17286} The homologous mutation in other kinases generated similar analog sensitivity (e.g., IC50 = 1.5 nM for c-Fyn-as1 versus 0.6 μM for c-Fyn; 7.0 nM for c-Abl-as2 versus 0.6 μM for c-Abl; 15 nM for Cdk2-as1 versus 18 μM for Cdk2).{17287} This approach has been used to elucidate functions of several kinases in both mammalian and yeast systems.{17287,20028,20029}  

     

    Brand:
    Cayman
    SKU:10954 - 10 mg

    Available on backorder

  • 1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become ‘analog sensitive’ (as), as compared to the wild-type kinase. 1-NA-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 1.5 nM versus 1.0 μM, respectively).{17286} The homologous mutation in other kinases generated similar analog sensitivity (e.g., IC50 = 1.5 nM for c-Fyn-as1 versus 0.6 μM for c-Fyn; 7.0 nM for c-Abl-as2 versus 0.6 μM for c-Abl; 15 nM for Cdk2-as1 versus 18 μM for Cdk2).{17287} This approach has been used to elucidate functions of several kinases in both mammalian and yeast systems.{17287,20028,20029}  

     

    Brand:
    Cayman
    SKU:10954 - 5 mg

    Available on backorder

  • 1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become ‘analog sensitive’ (as), as compared to the wild-type kinase. 1-NA-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 1.5 nM versus 1.0 μM, respectively).{17286} The homologous mutation in other kinases generated similar analog sensitivity (e.g., IC50 = 1.5 nM for c-Fyn-as1 versus 0.6 μM for c-Fyn; 7.0 nM for c-Abl-as2 versus 0.6 μM for c-Abl; 15 nM for Cdk2-as1 versus 18 μM for Cdk2).{17287} This approach has been used to elucidate functions of several kinases in both mammalian and yeast systems.{17287,20028,20029}  

     

    Brand:
    Cayman
    SKU:10954 - 50 mg

    Available on backorder

  • 1-Naphthyl 3,5-dinitrobenzoate has been identified as a dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor with IC50 values of 1 and 3.6 µM, respectively.{20842} The scaffold of this compound is being explored for anti-inflammatory drug design.{20842}  

     

    Brand:
    Cayman
    SKU:11729 - 1 mg

    Available on backorder

  • 1-Naphthyl 3,5-dinitrobenzoate has been identified as a dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor with IC50 values of 1 and 3.6 µM, respectively.{20842} The scaffold of this compound is being explored for anti-inflammatory drug design.{20842}  

     

    Brand:
    Cayman
    SKU:11729 - 10 mg

    Available on backorder

  • 1-Naphthyl 3,5-dinitrobenzoate has been identified as a dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor with IC50 values of 1 and 3.6 µM, respectively.{20842} The scaffold of this compound is being explored for anti-inflammatory drug design.{20842}  

     

    Brand:
    Cayman
    SKU:11729 - 25 mg

    Available on backorder

  • 1-Naphthyl 3,5-dinitrobenzoate has been identified as a dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor with IC50 values of 1 and 3.6 µM, respectively.{20842} The scaffold of this compound is being explored for anti-inflammatory drug design.{20842}  

     

    Brand:
    Cayman
    SKU:11729 - 5 mg

    Available on backorder

  • 1-NM-PP1 is a cell permeable inhibitor of kinases that have been mutated, by a single base substitution, to become ‘analog sensitive’ (as), as compared to the wild-type kinase. 1-NM-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 4.2 nM versus 28 μM, respectively).{17286} The homologous mutation in other kinases generated similar analog sensitivity (e.g., IC50 = 3.2 nM for c-Fyn-as1 versus 1.0 μM for c-Fyn; 5.0 nM for Cdk2-as1 versus 29 μM for Cdk2; 8.0 nM for CAMKII-as1 versus 24 μM for CAMKII).{17287} This approach has been used to elucidate functions of several kinases in both mammalian and yeast systems.{17287,17288,17289,17290,17291}  

     

    Brand:
    Cayman
    SKU:-
  • 1-NM-PP1 is a cell permeable inhibitor of kinases that have been mutated, by a single base substitution, to become ‘analog sensitive’ (as), as compared to the wild-type kinase. 1-NM-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 4.2 nM versus 28 μM, respectively).{17286} The homologous mutation in other kinases generated similar analog sensitivity (e.g., IC50 = 3.2 nM for c-Fyn-as1 versus 1.0 μM for c-Fyn; 5.0 nM for Cdk2-as1 versus 29 μM for Cdk2; 8.0 nM for CAMKII-as1 versus 24 μM for CAMKII).{17287} This approach has been used to elucidate functions of several kinases in both mammalian and yeast systems.{17287,17288,17289,17290,17291}  

     

    Brand:
    Cayman
    SKU:-
  • 1-NM-PP1 is a cell permeable inhibitor of kinases that have been mutated, by a single base substitution, to become ‘analog sensitive’ (as), as compared to the wild-type kinase. 1-NM-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 4.2 nM versus 28 μM, respectively).{17286} The homologous mutation in other kinases generated similar analog sensitivity (e.g., IC50 = 3.2 nM for c-Fyn-as1 versus 1.0 μM for c-Fyn; 5.0 nM for Cdk2-as1 versus 29 μM for Cdk2; 8.0 nM for CAMKII-as1 versus 24 μM for CAMKII).{17287} This approach has been used to elucidate functions of several kinases in both mammalian and yeast systems.{17287,17288,17289,17290,17291}  

     

    Brand:
    Cayman
    SKU:-
  • 1-NM-PP1 is a cell permeable inhibitor of kinases that have been mutated, by a single base substitution, to become ‘analog sensitive’ (as), as compared to the wild-type kinase. 1-NM-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 4.2 nM versus 28 μM, respectively).{17286} The homologous mutation in other kinases generated similar analog sensitivity (e.g., IC50 = 3.2 nM for c-Fyn-as1 versus 1.0 μM for c-Fyn; 5.0 nM for Cdk2-as1 versus 29 μM for Cdk2; 8.0 nM for CAMKII-as1 versus 24 μM for CAMKII).{17287} This approach has been used to elucidate functions of several kinases in both mammalian and yeast systems.{17287,17288,17289,17290,17291}  

     

    Brand:
    Cayman
    SKU:-
  • 1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether.{42507,42508} It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 (PGE2; Item No. 14010) in normal human epidermal keratinocytes (NHEKs).{42507} 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury.{42508}  

     

    Brand:
    Cayman
    SKU:25723 - 1 g

    Available on backorder

  • 1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether.{42507,42508} It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 (PGE2; Item No. 14010) in normal human epidermal keratinocytes (NHEKs).{42507} 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury.{42508}  

     

    Brand:
    Cayman
    SKU:25723 - 100 mg

    Available on backorder

  • 1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether.{42507,42508} It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 (PGE2; Item No. 14010) in normal human epidermal keratinocytes (NHEKs).{42507} 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury.{42508}  

     

    Brand:
    Cayman
    SKU:25723 - 250 mg

    Available on backorder

  • 1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether.{42507,42508} It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 (PGE2; Item No. 14010) in normal human epidermal keratinocytes (NHEKs).{42507} 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury.{42508}  

     

    Brand:
    Cayman
    SKU:25723 - 500 mg

    Available on backorder

  • 1-O-Octadecyl-2-O-methyl-sn-glycerol is a metabolite of a phosphotidylinositol ether lipid analog (PIA). PIAs are known to target the pleckstrin homology domain of the serine/threonine kinase Akt and to induce apoptosis in cancer cell lines with high levels of endogenous Akt activity.{24386,24385}  

     

    Brand:
    Cayman
    SKU:-
  • 1-O-Octadecyl-2-O-methyl-sn-glycerol is a metabolite of a phosphotidylinositol ether lipid analog (PIA). PIAs are known to target the pleckstrin homology domain of the serine/threonine kinase Akt and to induce apoptosis in cancer cell lines with high levels of endogenous Akt activity.{24386,24385}  

     

    Brand:
    Cayman
    SKU:-
  • 1-O-Octadecyl-2-O-methyl-sn-glycerol is a metabolite of a phosphotidylinositol ether lipid analog (PIA). PIAs are known to target the pleckstrin homology domain of the serine/threonine kinase Akt and to induce apoptosis in cancer cell lines with high levels of endogenous Akt activity.{24386,24385}  

     

    Brand:
    Cayman
    SKU:-
  • 1-O-Octadecyl-2-O-methyl-sn-glycerol is a metabolite of a phosphotidylinositol ether lipid analog (PIA). PIAs are known to target the pleckstrin homology domain of the serine/threonine kinase Akt and to induce apoptosis in cancer cell lines with high levels of endogenous Akt activity.{24386,24385}  

     

    Brand:
    Cayman
    SKU:-
  • 1-Octacosanol is a very long-chain fatty alcohol that has diverse biological activities, including antibacterial, antifungal, anti-inflammatory, and antioxidative properties.{45357,45358,45359} It is active against the bacteria K. pneumoniae, S. flexneri, S. typhi, and E. faecalis (MICs = 4, 8, 2, and 32 µg/ml, respectively), as well as the pathogenic fungi T. ajelloi and T. rubrum (MICs = 4 and 32 µg/ml, respectively), but not the yeast C. albicans, C. lusitaniae, or C. krusei.{45357} It reduces the expression of TNF-α, inducible nitric oxide synthase (iNOS), IL-1β, and IL-6 in RAW 264.7 cells stimulated with LPS when used at concentrations of 30 and 100 µg/ml.{45359} 1-Octacosanol (100 mg/kg per day) increases body weight, decreases diarrhea and hematochezia, and improves histopathological and morphological changes in the colon in a mouse model of ulcerative colitis induced by dextran sulfate sodium (DSS; Item No. 23250). 1-Octacosanol (10, 50, or 100 mg/kg) reduces carbon tetrachloride-induced increases in serum transaminase, hepatic myeloperoxidase, and hepatic xanthine oxidase activity, as well as lipid peroxidation, in a rat model of acute liver injury progression.{45358} It also reverses decreases in hepatic superoxide dismutase and catalase activity, as well as glutathione (GSH) levels, in the same model.  

     

    Brand:
    Cayman
    SKU:28010 - 1 g

    Available on backorder

  • 1-Octacosanol is a very long-chain fatty alcohol that has diverse biological activities, including antibacterial, antifungal, anti-inflammatory, and antioxidative properties.{45357,45358,45359} It is active against the bacteria K. pneumoniae, S. flexneri, S. typhi, and E. faecalis (MICs = 4, 8, 2, and 32 µg/ml, respectively), as well as the pathogenic fungi T. ajelloi and T. rubrum (MICs = 4 and 32 µg/ml, respectively), but not the yeast C. albicans, C. lusitaniae, or C. krusei.{45357} It reduces the expression of TNF-α, inducible nitric oxide synthase (iNOS), IL-1β, and IL-6 in RAW 264.7 cells stimulated with LPS when used at concentrations of 30 and 100 µg/ml.{45359} 1-Octacosanol (100 mg/kg per day) increases body weight, decreases diarrhea and hematochezia, and improves histopathological and morphological changes in the colon in a mouse model of ulcerative colitis induced by dextran sulfate sodium (DSS; Item No. 23250). 1-Octacosanol (10, 50, or 100 mg/kg) reduces carbon tetrachloride-induced increases in serum transaminase, hepatic myeloperoxidase, and hepatic xanthine oxidase activity, as well as lipid peroxidation, in a rat model of acute liver injury progression.{45358} It also reverses decreases in hepatic superoxide dismutase and catalase activity, as well as glutathione (GSH) levels, in the same model.  

     

    Brand:
    Cayman
    SKU:28010 - 100 mg

    Available on backorder

  • 1-Octacosanol is a very long-chain fatty alcohol that has diverse biological activities, including antibacterial, antifungal, anti-inflammatory, and antioxidative properties.{45357,45358,45359} It is active against the bacteria K. pneumoniae, S. flexneri, S. typhi, and E. faecalis (MICs = 4, 8, 2, and 32 µg/ml, respectively), as well as the pathogenic fungi T. ajelloi and T. rubrum (MICs = 4 and 32 µg/ml, respectively), but not the yeast C. albicans, C. lusitaniae, or C. krusei.{45357} It reduces the expression of TNF-α, inducible nitric oxide synthase (iNOS), IL-1β, and IL-6 in RAW 264.7 cells stimulated with LPS when used at concentrations of 30 and 100 µg/ml.{45359} 1-Octacosanol (100 mg/kg per day) increases body weight, decreases diarrhea and hematochezia, and improves histopathological and morphological changes in the colon in a mouse model of ulcerative colitis induced by dextran sulfate sodium (DSS; Item No. 23250). 1-Octacosanol (10, 50, or 100 mg/kg) reduces carbon tetrachloride-induced increases in serum transaminase, hepatic myeloperoxidase, and hepatic xanthine oxidase activity, as well as lipid peroxidation, in a rat model of acute liver injury progression.{45358} It also reverses decreases in hepatic superoxide dismutase and catalase activity, as well as glutathione (GSH) levels, in the same model.  

     

    Brand:
    Cayman
    SKU:28010 - 500 mg

    Available on backorder

  • 1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM.{15053}  

     

    Brand:
    Cayman
    SKU:10010164 - 1 mg

    Available on backorder

  • 1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM.{15053}  

     

    Brand:
    Cayman
    SKU:10010164 - 10 mg

    Available on backorder

  • 1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM.{15053}  

     

    Brand:
    Cayman
    SKU:10010164 - 5 mg

    Available on backorder

  • 1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM.{15053}  

     

    Brand:
    Cayman
    SKU:10010164 - 500 µg

    Available on backorder

  • 1-Octanoyl-2-decanoyl-3-stearoyl-rac-glycerol is a triacylglycerol that contains octanoic acid, decanoic acid (Item No. 20838), and stearic acid (Item No. 10011298) at the sn-1, sn-2, and sn-3 positions, respectively.  

     

    Brand:
    Cayman
    SKU:29237 - 1 mg

    Available on backorder

  • 1-Octanoyl-2-decanoyl-3-stearoyl-rac-glycerol is a triacylglycerol that contains octanoic acid, decanoic acid (Item No. 20838), and stearic acid (Item No. 10011298) at the sn-1, sn-2, and sn-3 positions, respectively.  

     

    Brand:
    Cayman
    SKU:29237 - 10 mg

    Available on backorder

  • 1-Octanoyl-2-decanoyl-3-stearoyl-rac-glycerol is a triacylglycerol that contains octanoic acid, decanoic acid (Item No. 20838), and stearic acid (Item No. 10011298) at the sn-1, sn-2, and sn-3 positions, respectively.  

     

    Brand:
    Cayman
    SKU:29237 - 25 mg

    Available on backorder

  • 1-Octanoyl-2-decanoyl-3-stearoyl-rac-glycerol is a triacylglycerol that contains octanoic acid, decanoic acid (Item No. 20838), and stearic acid (Item No. 10011298) at the sn-1, sn-2, and sn-3 positions, respectively.  

     

    Brand:
    Cayman
    SKU:29237 - 5 mg

    Available on backorder

  • 1-Octanoyl-rac-glycerol is a monoacylglycerol that contains octanoic acid at the sn-1 position. It reduces the growth of a variety of bacteria and pathogenic fungi, including C. albicans and C. parapsilosis, on textiles when applied as a 15 wt% solution in ethanol.{47412} 1-Octanoyl-rac-glycerol, in combination with ethanol or 2-mercaptoethanol, dissolves gallstones in vitro.{47413}  

     

    Brand:
    Cayman
    SKU:26945 - 1 g

    Available on backorder

  • 1-Octanoyl-rac-glycerol is a monoacylglycerol that contains octanoic acid at the sn-1 position. It reduces the growth of a variety of bacteria and pathogenic fungi, including C. albicans and C. parapsilosis, on textiles when applied as a 15 wt% solution in ethanol.{47412} 1-Octanoyl-rac-glycerol, in combination with ethanol or 2-mercaptoethanol, dissolves gallstones in vitro.{47413}  

     

    Brand:
    Cayman
    SKU:26945 - 250 mg

    Available on backorder

  • 1-Octanoyl-rac-glycerol is a monoacylglycerol that contains octanoic acid at the sn-1 position. It reduces the growth of a variety of bacteria and pathogenic fungi, including C. albicans and C. parapsilosis, on textiles when applied as a 15 wt% solution in ethanol.{47412} 1-Octanoyl-rac-glycerol, in combination with ethanol or 2-mercaptoethanol, dissolves gallstones in vitro.{47413}  

     

    Brand:
    Cayman
    SKU:26945 - 500 mg

    Available on backorder

  • 1-Oleoyl glycerol is a monoacylglycerol containing oleic acid (Item No. 90260) at the sn-1 position. 1-Oleoyl glycerol (10%), in a formulation with cyclosporin A (Item No. 12088) in propylene glycol, enhances diffusion of cyclosporin A from the donor compartment of a Franz diffusion cell into the stratum corneum, epidermis, and dermis of porcine ear skin, as well as through the skin to the receptor compartment.{48157} Mixed micellar systems containing 1-oleoyl glycerol and bile salts increase the apparent permeability coefficient (Papp) and absorption rate of amphotericin B (Item No. 11636) in perfused rat intestine in vivo.{48158} Formulations containing 1-oleoyl glycerol have been used as emulsifying agents, food additives, and absorption enhancers.  

     

    Brand:
    Cayman
    SKU:26793 - 1 g

    Available on backorder

  • 1-Oleoyl glycerol is a monoacylglycerol containing oleic acid (Item No. 90260) at the sn-1 position. 1-Oleoyl glycerol (10%), in a formulation with cyclosporin A (Item No. 12088) in propylene glycol, enhances diffusion of cyclosporin A from the donor compartment of a Franz diffusion cell into the stratum corneum, epidermis, and dermis of porcine ear skin, as well as through the skin to the receptor compartment.{48157} Mixed micellar systems containing 1-oleoyl glycerol and bile salts increase the apparent permeability coefficient (Papp) and absorption rate of amphotericin B (Item No. 11636) in perfused rat intestine in vivo.{48158} Formulations containing 1-oleoyl glycerol have been used as emulsifying agents, food additives, and absorption enhancers.  

     

    Brand:
    Cayman
    SKU:26793 - 250 mg

    Available on backorder

  • 1-Oleoyl glycerol is a monoacylglycerol containing oleic acid (Item No. 90260) at the sn-1 position. 1-Oleoyl glycerol (10%), in a formulation with cyclosporin A (Item No. 12088) in propylene glycol, enhances diffusion of cyclosporin A from the donor compartment of a Franz diffusion cell into the stratum corneum, epidermis, and dermis of porcine ear skin, as well as through the skin to the receptor compartment.{48157} Mixed micellar systems containing 1-oleoyl glycerol and bile salts increase the apparent permeability coefficient (Papp) and absorption rate of amphotericin B (Item No. 11636) in perfused rat intestine in vivo.{48158} Formulations containing 1-oleoyl glycerol have been used as emulsifying agents, food additives, and absorption enhancers.  

     

    Brand:
    Cayman
    SKU:26793 - 500 mg

    Available on backorder

  • 1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed by phosphorylation of DAG by diglycerol kinase.{2656} Hydrolysis of the fatty acid at the sn-2 position by phospholipase A2 (PLA2) yields bioactive LPA. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} 1-Oleoyl lysophosphatidic acid is the most potent of the LPA analogs for calcium mobilization in A431 cells and for growth stimulation of a variety of cell lines.{2665,2666}  

     

    Brand:
    Cayman
    SKU:10010093 - 1 mg

    Available on backorder

  • 1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed by phosphorylation of DAG by diglycerol kinase.{2656} Hydrolysis of the fatty acid at the sn-2 position by phospholipase A2 (PLA2) yields bioactive LPA. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} 1-Oleoyl lysophosphatidic acid is the most potent of the LPA analogs for calcium mobilization in A431 cells and for growth stimulation of a variety of cell lines.{2665,2666}  

     

    Brand:
    Cayman
    SKU:10010093 - 10 mg

    Available on backorder

  • 1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed by phosphorylation of DAG by diglycerol kinase.{2656} Hydrolysis of the fatty acid at the sn-2 position by phospholipase A2 (PLA2) yields bioactive LPA. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} 1-Oleoyl lysophosphatidic acid is the most potent of the LPA analogs for calcium mobilization in A431 cells and for growth stimulation of a variety of cell lines.{2665,2666}  

     

    Brand:
    Cayman
    SKU:10010093 - 25 mg

    Available on backorder

  • 1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed by phosphorylation of DAG by diglycerol kinase.{2656} Hydrolysis of the fatty acid at the sn-2 position by phospholipase A2 (PLA2) yields bioactive LPA. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} 1-Oleoyl lysophosphatidic acid is the most potent of the LPA analogs for calcium mobilization in A431 cells and for growth stimulation of a variety of cell lines.{2665,2666}  

     

    Brand:
    Cayman
    SKU:10010093 - 5 mg

    Available on backorder

  • 1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of PLD or through a two step process involving liberation of DAG by PLC followed by phosphorylation of DAG by diglycerol kinase.{2656} Hydrolysis of the fatty acid at the sn-2 position by PLA2 yields bioactive LPA. LPA binds to one of four different G-protein linked receptors{13001} to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{2656} 1-Oleoyl lysophosphatidic acid is the most potent of the LPA analogs for calcium mobilization in A431 cells{2665} and for growth stimulation of a variety of cell lines.{2666}  

     

    Brand:
    Cayman
    SKU:62215 - 1 mg

    Available on backorder

  • 1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of PLD or through a two step process involving liberation of DAG by PLC followed by phosphorylation of DAG by diglycerol kinase.{2656} Hydrolysis of the fatty acid at the sn-2 position by PLA2 yields bioactive LPA. LPA binds to one of four different G-protein linked receptors{13001} to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{2656} 1-Oleoyl lysophosphatidic acid is the most potent of the LPA analogs for calcium mobilization in A431 cells{2665} and for growth stimulation of a variety of cell lines.{2666}  

     

    Brand:
    Cayman
    SKU:62215 - 10 mg

    Available on backorder

  • 1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of PLD or through a two step process involving liberation of DAG by PLC followed by phosphorylation of DAG by diglycerol kinase.{2656} Hydrolysis of the fatty acid at the sn-2 position by PLA2 yields bioactive LPA. LPA binds to one of four different G-protein linked receptors{13001} to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{2656} 1-Oleoyl lysophosphatidic acid is the most potent of the LPA analogs for calcium mobilization in A431 cells{2665} and for growth stimulation of a variety of cell lines.{2666}  

     

    Brand:
    Cayman
    SKU:62215 - 5 mg

    Available on backorder

  • 1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of PLD or through a two step process involving liberation of DAG by PLC followed by phosphorylation of DAG by diglycerol kinase.{2656} Hydrolysis of the fatty acid at the sn-2 position by PLA2 yields bioactive LPA. LPA binds to one of four different G-protein linked receptors{13001} to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{2656} 1-Oleoyl lysophosphatidic acid is the most potent of the LPA analogs for calcium mobilization in A431 cells{2665} and for growth stimulation of a variety of cell lines.{2666}  

     

    Brand:
    Cayman
    SKU:62215 - 50 mg

    Available on backorder

  • OAG is a cell-permeable analog of the PKC-activating second messenger DAG. It activates PKC in platelets, resulting in the phosphorylation of a 40 kDa protein. OAG is metabolized to its corresponding phosphatidic acid (1-oleoyl-2-acetyl-3-phosphoglycerol), most likely through the action of a diglycerol kinase.{656}  

     

    Brand:
    Cayman
    SKU:62600 - 10 mg

    Available on backorder

  • OAG is a cell-permeable analog of the PKC-activating second messenger DAG. It activates PKC in platelets, resulting in the phosphorylation of a 40 kDa protein. OAG is metabolized to its corresponding phosphatidic acid (1-oleoyl-2-acetyl-3-phosphoglycerol), most likely through the action of a diglycerol kinase.{656}  

     

    Brand:
    Cayman
    SKU:62600 - 100 mg

    Available on backorder

  • OAG is a cell-permeable analog of the PKC-activating second messenger DAG. It activates PKC in platelets, resulting in the phosphorylation of a 40 kDa protein. OAG is metabolized to its corresponding phosphatidic acid (1-oleoyl-2-acetyl-3-phosphoglycerol), most likely through the action of a diglycerol kinase.{656}  

     

    Brand:
    Cayman
    SKU:62600 - 25 mg

    Available on backorder

  • OAG is a cell-permeable analog of the PKC-activating second messenger DAG. It activates PKC in platelets, resulting in the phosphorylation of a 40 kDa protein. OAG is metabolized to its corresponding phosphatidic acid (1-oleoyl-2-acetyl-3-phosphoglycerol), most likely through the action of a diglycerol kinase.{656}  

     

    Brand:
    Cayman
    SKU:62600 - 50 mg

    Available on backorder

  • 1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine.{36851,36852,36853} It induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid receptor 1 (LPA1) antagonist AM095 (Item No. 22141).{36852} 1-Oleoyl-2-hydroxy-sn-glycero-3-PE (100 ng/ml) increases IL-2 production in CD1d-stimulated murine natural killer T (NKT) cell hybridoma 2H4 cells.{36853} It also induces production of IL-4, but not IFN-γ, in murine splenocytes when used at a concentration of 100 ng/ml and in mouse serum when administered at a dose of 1 μg per animal, indicating induction of the T helper 2 (Th2) response. 1-Oleoyl-2-hydroxy-sn-glycero-3-PE levels increase in interscapular brown adipose tissue (iBAT) in mice following three-day cold exposure.{36851}  

     

    Brand:
    Cayman
    SKU:25596 - 10 mg

    Available on backorder

  • 1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine.{36851,36852,36853} It induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid receptor 1 (LPA1) antagonist AM095 (Item No. 22141).{36852} 1-Oleoyl-2-hydroxy-sn-glycero-3-PE (100 ng/ml) increases IL-2 production in CD1d-stimulated murine natural killer T (NKT) cell hybridoma 2H4 cells.{36853} It also induces production of IL-4, but not IFN-γ, in murine splenocytes when used at a concentration of 100 ng/ml and in mouse serum when administered at a dose of 1 μg per animal, indicating induction of the T helper 2 (Th2) response. 1-Oleoyl-2-hydroxy-sn-glycero-3-PE levels increase in interscapular brown adipose tissue (iBAT) in mice following three-day cold exposure.{36851}  

     

    Brand:
    Cayman
    SKU:25596 - 25 mg

    Available on backorder

  • 1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine.{36851,36852,36853} It induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid receptor 1 (LPA1) antagonist AM095 (Item No. 22141).{36852} 1-Oleoyl-2-hydroxy-sn-glycero-3-PE (100 ng/ml) increases IL-2 production in CD1d-stimulated murine natural killer T (NKT) cell hybridoma 2H4 cells.{36853} It also induces production of IL-4, but not IFN-γ, in murine splenocytes when used at a concentration of 100 ng/ml and in mouse serum when administered at a dose of 1 μg per animal, indicating induction of the T helper 2 (Th2) response. 1-Oleoyl-2-hydroxy-sn-glycero-3-PE levels increase in interscapular brown adipose tissue (iBAT) in mice following three-day cold exposure.{36851}  

     

    Brand:
    Cayman
    SKU:25596 - 5 mg

    Available on backorder

  • 1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine.{36851,36852,36853} It induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid receptor 1 (LPA1) antagonist AM095 (Item No. 22141).{36852} 1-Oleoyl-2-hydroxy-sn-glycero-3-PE (100 ng/ml) increases IL-2 production in CD1d-stimulated murine natural killer T (NKT) cell hybridoma 2H4 cells.{36853} It also induces production of IL-4, but not IFN-γ, in murine splenocytes when used at a concentration of 100 ng/ml and in mouse serum when administered at a dose of 1 μg per animal, indicating induction of the T helper 2 (Th2) response. 1-Oleoyl-2-hydroxy-sn-glycero-3-PE levels increase in interscapular brown adipose tissue (iBAT) in mice following three-day cold exposure.{36851}  

     

    Brand:
    Cayman
    SKU:25596 - 50 mg

    Available on backorder

  • 1-Oleoyl-2-hydroxy-sn-glycero-3-PG (sodium salt) is a lysophospholipid containing oleic acid (18:1) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.{33498,33497}  

     

    Brand:
    Cayman
    SKU:20960 -

    Out of stock

  • 1-Oleoyl-2-hydroxy-sn-glycero-3-PG (sodium salt) is a lysophospholipid containing oleic acid (18:1) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.{33498,33497}  

     

    Brand:
    Cayman
    SKU:20960 -

    Out of stock