Cayman
Showing 1501–1650 of 45550 results
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1-(3-Chlorophenyl)piperazine (mCPP) is a psychoactive compound which is commonly abused worldwide.{20497,19874} A phenylpiperazine, this compound has been extensively studied and found to produce diverse physiological and emotional effects.{19874,21515,20499} This product is intended for forensic and research purposes.
Brand:CaymanSKU:- 1-(3-Chlorophenyl)piperazine (mCPP) is a psychoactive compound which is commonly abused worldwide.{20497,19874} A phenylpiperazine, this compound has been extensively studied and found to produce diverse physiological and emotional effects.{19874,21515,20499} This product is intended for forensic and research purposes.
Brand:CaymanSKU:-
1-(3-Fluorophenyl)piperazine (hydrochloride) (Item No. 21953) is an analytical reference standard that is categorized as a piperazine. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Brand:CaymanSKU:21953 -Out of stock
1-(3-Fluorophenyl)piperazine (hydrochloride) (Item No. 21953) is an analytical reference standard that is categorized as a piperazine. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Brand:CaymanSKU:21953 -Out of stock
1-(3-Methoxyphenyl)piperazine (Item No. 19273) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
1-(3-Methoxyphenyl)piperazine (Item No. 19273) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
1-(3-Methoxyphenyl)piperazine (Item No. 19273) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.
Brand:CaymanSKU:-Available on backorder
1-(3-Methylbenzyl)piperazine (Item No. 24018) is an analytical reference standard categorized as a piperazine. It has been detected in illicit tablets.{41394} This product is intended for research and forensic applications.
Brand:CaymanSKU:24018 - 1 mgAvailable on backorder
1-(3-Methylbenzyl)piperazine (Item No. 24018) is an analytical reference standard categorized as a piperazine. It has been detected in illicit tablets.{41394} This product is intended for research and forensic applications.
Brand:CaymanSKU:24018 - 5 mgAvailable on backorder
1-(3-Methylbenzyl)piperazine (Item No. 24018) is an analytical reference standard categorized as a piperazine. It has been detected in illicit tablets.{41394} This product is intended for research and forensic applications.
Brand:CaymanSKU:24018 - 50 mgAvailable on backorder
1-(3-Trifluoromethylphenyl)piperazine (TFMPP) is an entactogenic drug which selectively promotes the release of serotonin.{20498} When used in combination with 1-benzylpiperazine, TFMPP increases both serotonin and dopamine, mirroring the effects of 3,4-methylenedioxymethamphetamine.{20498} Drug-drug synergism may induce seizures.{20498} TFMPP has been identified in party pills and powders.{20500,20497} Its metabolism in rats has been described.{19874} This product is intended for forensic applications.
Brand:CaymanSKU:11205 - 10 mgAvailable on backorder
1-(3-Trifluoromethylphenyl)piperazine (TFMPP) is an entactogenic drug which selectively promotes the release of serotonin.{20498} When used in combination with 1-benzylpiperazine, TFMPP increases both serotonin and dopamine, mirroring the effects of 3,4-methylenedioxymethamphetamine.{20498} Drug-drug synergism may induce seizures.{20498} TFMPP has been identified in party pills and powders.{20500,20497} Its metabolism in rats has been described.{19874} This product is intended for forensic applications.
Brand:CaymanSKU:11205 - 100 mgAvailable on backorder
1-(3-Trifluoromethylphenyl)piperazine (TFMPP) is an entactogenic drug which selectively promotes the release of serotonin.{20498} When used in combination with 1-benzylpiperazine, TFMPP increases both serotonin and dopamine, mirroring the effects of 3,4-methylenedioxymethamphetamine.{20498} Drug-drug synergism may induce seizures.{20498} TFMPP has been identified in party pills and powders.{20500,20497} Its metabolism in rats has been described.{19874} This product is intended for forensic applications.
Brand:CaymanSKU:11205 - 50 mgAvailable on backorder
1-(3,5-Dimethylphenyl)piperazine is a piperidine compound that is inactive at dopamine and serotonin receptors.{32836} It may be used as a heterocyclic building block to develop bioactive compounds.
Brand:CaymanSKU:20627 -Available on backorder
1-(3,5-Dimethylphenyl)piperazine is a piperidine compound that is inactive at dopamine and serotonin receptors.{32836} It may be used as a heterocyclic building block to develop bioactive compounds.
Brand:CaymanSKU:20627 -Available on backorder
1-(3,5-Dimethylphenyl)piperazine is a piperidine compound that is inactive at dopamine and serotonin receptors.{32836} It may be used as a heterocyclic building block to develop bioactive compounds.
Brand:CaymanSKU:20627 -Available on backorder
1-(4-Bromophenyl)piperazine (hydrochloride) (Item No. 30229) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.
Brand:CaymanSKU:30229 - 1 mgAvailable on backorder
1-(4-Bromophenyl)piperazine (hydrochloride) (Item No. 30229) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.
Brand:CaymanSKU:30229 - 5 mgAvailable on backorder
1-(4-Chlorophenyl)piperazine (Item No. 14481) is an analytical reference standard categorized as a piperazine. It is psychoactive and an isomer of 1-(3-chlorophenyl)piperazine (Item No. 13949).{40610} This product is intended for research and forensic applications.
Brand:CaymanSKU:- 1-(4-Chlorophenyl)piperazine (Item No. 14481) is an analytical reference standard categorized as a piperazine. It is psychoactive and an isomer of 1-(3-chlorophenyl)piperazine (Item No. 13949).{40610} This product is intended for research and forensic applications.
Brand:CaymanSKU:- 1-(4-Chlorophenyl)piperazine (Item No. 14481) is an analytical reference standard categorized as a piperazine. It is psychoactive and an isomer of 1-(3-chlorophenyl)piperazine (Item No. 13949).{40610} This product is intended for research and forensic applications.
Brand:CaymanSKU:-
1-(4-Fluorophenyl)-2-methyl-2-propylamine is a fluorinated building block used for the synthesis of various pharmaceutical amides.
Brand:CaymanSKU:9002780 - 100 mgAvailable on backorder
1-(4-Fluorophenyl)-2-methyl-2-propylamine is a fluorinated building block used for the synthesis of various pharmaceutical amides.
Brand:CaymanSKU:9002780 - 250 mgAvailable on backorder
1-(4-Fluorophenyl)-2-methyl-2-propylamine is a fluorinated building block used for the synthesis of various pharmaceutical amides.
Brand:CaymanSKU:9002780 - 50 mgAvailable on backorder
Phenylpiperazines are entactogenic drugs which direct central serotonin release.{20499,20498,20500} Substituted phenylpiperazines, such as 1-(3-chlorophenyl)piperazine, have been identified as designer drugs or drugs of abuse.{19758,20497} 1-(4Fluorophenyl)piperazine (hydrochloride) is a substituted phenylpiperazine with a potential for abuse. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.
Brand:CaymanSKU:11204 - 10 mgAvailable on backorder
Phenylpiperazines are entactogenic drugs which direct central serotonin release.{20499,20498,20500} Substituted phenylpiperazines, such as 1-(3-chlorophenyl)piperazine, have been identified as designer drugs or drugs of abuse.{19758,20497} 1-(4Fluorophenyl)piperazine (hydrochloride) is a substituted phenylpiperazine with a potential for abuse. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.
Brand:CaymanSKU:11204 - 100 mgAvailable on backorder
Phenylpiperazines are entactogenic drugs which direct central serotonin release.{20499,20498,20500} Substituted phenylpiperazines, such as 1-(3-chlorophenyl)piperazine, have been identified as designer drugs or drugs of abuse.{19758,20497} 1-(4Fluorophenyl)piperazine (hydrochloride) is a substituted phenylpiperazine with a potential for abuse. The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.
Brand:CaymanSKU:11204 - 50 mgAvailable on backorder
1-(4-Methoxyphenyl)piperazine (hydrochloride) is a piperazine derivative with euphoric, stimulant properties comparable to those produced by amphetamine.{19874,21281} It is assumed to have a mixed mechanism of action, with serotonergic and dopamine antagonistic properties in a similar fashion to 3,4-methylenedioxymethamphetamine. Also, its metabolism has been described.{19874,20497} This product is intended for research and forensic purposes.
Brand:CaymanSKU:- 1-(4-Methoxyphenyl)piperazine (hydrochloride) is a piperazine derivative with euphoric, stimulant properties comparable to those produced by amphetamine.{19874,21281} It is assumed to have a mixed mechanism of action, with serotonergic and dopamine antagonistic properties in a similar fashion to 3,4-methylenedioxymethamphetamine. Also, its metabolism has been described.{19874,20497} This product is intended for research and forensic purposes.
Brand:CaymanSKU:- 1-(4-Methoxyphenyl)piperazine (hydrochloride) is a piperazine derivative with euphoric, stimulant properties comparable to those produced by amphetamine.{19874,21281} It is assumed to have a mixed mechanism of action, with serotonergic and dopamine antagonistic properties in a similar fashion to 3,4-methylenedioxymethamphetamine. Also, its metabolism has been described.{19874,20497} This product is intended for research and forensic purposes.
Brand:CaymanSKU:-
1-(6-Methoxy-2-naphthyl)ethanol is a potential impurity in commercial preparations of naproxen.{38232} Naproxen (Item No. 70290) is a non-selective COX inhibitor.{1286,1791} The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 µM and 2.0-28.4 µM, respectively.
Brand:CaymanSKU:22162 -Out of stock
1-(6-Methoxy-2-naphthyl)ethanol is a potential impurity in commercial preparations of naproxen.{38232} Naproxen (Item No. 70290) is a non-selective COX inhibitor.{1286,1791} The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 µM and 2.0-28.4 µM, respectively.
Brand:CaymanSKU:22162 -Out of stock
1-(6-Methoxy-2-naphthyl)ethanol is a potential impurity in commercial preparations of naproxen.{38232} Naproxen (Item No. 70290) is a non-selective COX inhibitor.{1286,1791} The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 µM and 2.0-28.4 µM, respectively.
Brand:CaymanSKU:22162 -Out of stock
1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium (bromide) is a fluorescent indicator dye that can be used to measure intracellular and extracellular chloride concentrations (absorption/emission max: 350/460 nm).{22804} It detects the ion via diffusion-limited collisional quenching.
Brand:CaymanSKU:19585 -Available on backorder
1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium (bromide) is a fluorescent indicator dye that can be used to measure intracellular and extracellular chloride concentrations (absorption/emission max: 350/460 nm).{22804} It detects the ion via diffusion-limited collisional quenching.
Brand:CaymanSKU:19585 -Available on backorder
1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium (bromide) is a fluorescent indicator dye that can be used to measure intracellular and extracellular chloride concentrations (absorption/emission max: 350/460 nm).{22804} It detects the ion via diffusion-limited collisional quenching.
Brand:CaymanSKU:19585 -Available on backorder
1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium (bromide) is a fluorescent indicator dye that can be used to measure intracellular and extracellular chloride concentrations (absorption/emission max: 350/460 nm).{22804} It detects the ion via diffusion-limited collisional quenching.
Brand:CaymanSKU:19585 -Available on backorder
1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PC is a plasmalogen that has been found in various rat tissues, including the liver, heart, kidney, gluteus muscle, soleus muscle, and visceral and subcutaneous adipose tissue.{52046} It has been used in the synthesis of lipid bilayers to quantify the effects of amphiphilic compounds, such as lysophosphatidylcholine (1-palmitoyl-2-hydroxy-sn-glycero-3-PC; Item No. 10172) and lysoplasmenylcholine, on membrane dynamics.{52047}
Brand:CaymanSKU:28348 - 1 mgAvailable on backorder
1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PC is a plasmalogen that has been found in various rat tissues, including the liver, heart, kidney, gluteus muscle, soleus muscle, and visceral and subcutaneous adipose tissue.{52046} It has been used in the synthesis of lipid bilayers to quantify the effects of amphiphilic compounds, such as lysophosphatidylcholine (1-palmitoyl-2-hydroxy-sn-glycero-3-PC; Item No. 10172) and lysoplasmenylcholine, on membrane dynamics.{52047}
Brand:CaymanSKU:28348 - 25 mgAvailable on backorder
1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PC is a plasmalogen that has been found in various rat tissues, including the liver, heart, kidney, gluteus muscle, soleus muscle, and visceral and subcutaneous adipose tissue.{52046} It has been used in the synthesis of lipid bilayers to quantify the effects of amphiphilic compounds, such as lysophosphatidylcholine (1-palmitoyl-2-hydroxy-sn-glycero-3-PC; Item No. 10172) and lysoplasmenylcholine, on membrane dynamics.{52047}
Brand:CaymanSKU:28348 - 5 mgAvailable on backorder
1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PE is a plasmalogen that contains 1(Z)-hexadecanoic acid and palmitic acid (Item No. 10006627) at the sn-1 and sn-2 positions, respectively.
Brand:CaymanSKU:28349 - 1 mgAvailable on backorder
1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PE is a plasmalogen that contains 1(Z)-hexadecanoic acid and palmitic acid (Item No. 10006627) at the sn-1 and sn-2 positions, respectively.
Brand:CaymanSKU:28349 - 5 mgAvailable on backorder
1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PE is a plasmalogen that contains 1(Z)-hexadecanoic acid and palmitic acid (Item No. 10006627) at the sn-1 and sn-2 positions, respectively.
Brand:CaymanSKU:28349 - 500 µgAvailable on backorder
1-Alaninechlamydocin is a fungal metabolite originally isolated from a Great Lakes-derived Tolypocladium sp. and an inhibitor of histone deacetylases (HDACs).{46278} It reduces total HDAC activity in HeLa cell lysates in a concentration-dependent manner. 1-Alaninechlamydocin reduces proliferation of MIA PaCa-2, PANC-1, and hTERT-HPNE cells (GI50s = 5.3, 14, and 2.0 nM, respectively).
Brand:CaymanSKU:28102 - 2.5 mgAvailable on backorder
1-Alaninechlamydocin is a fungal metabolite originally isolated from a Great Lakes-derived Tolypocladium sp. and an inhibitor of histone deacetylases (HDACs).{46278} It reduces total HDAC activity in HeLa cell lysates in a concentration-dependent manner. 1-Alaninechlamydocin reduces proliferation of MIA PaCa-2, PANC-1, and hTERT-HPNE cells (GI50s = 5.3, 14, and 2.0 nM, respectively).
Brand:CaymanSKU:28102 - 500 µgAvailable on backorder
1-Amino-1-deoxy-D-fructose is an amino monosaccharide.{53651} It induces site-specific DNA damage at pyrimidine residues in cell-free assays. 1-Amino-1-deoxy-D-fructose moieties have been found as a component of fructosamines, glycated serum proteins that are elevated in patients with conditions such as diabetes.{53652,53653}
Brand:CaymanSKU:30571 - 100 mgAvailable on backorder
1-Amino-1-deoxy-D-fructose is an amino monosaccharide.{53651} It induces site-specific DNA damage at pyrimidine residues in cell-free assays. 1-Amino-1-deoxy-D-fructose moieties have been found as a component of fructosamines, glycated serum proteins that are elevated in patients with conditions such as diabetes.{53652,53653}
Brand:CaymanSKU:30571 - 250 mgAvailable on backorder
1-Amino-1-deoxy-D-fructose is an amino monosaccharide.{53651} It induces site-specific DNA damage at pyrimidine residues in cell-free assays. 1-Amino-1-deoxy-D-fructose moieties have been found as a component of fructosamines, glycated serum proteins that are elevated in patients with conditions such as diabetes.{53652,53653}
Brand:CaymanSKU:30571 - 50 mgAvailable on backorder
1-Amino-1-deoxy-D-fructose is an amino monosaccharide.{53651} It induces site-specific DNA damage at pyrimidine residues in cell-free assays. 1-Amino-1-deoxy-D-fructose moieties have been found as a component of fructosamines, glycated serum proteins that are elevated in patients with conditions such as diabetes.{53652,53653}
Brand:CaymanSKU:30571 - 500 mgAvailable on backorder
1-aminobenzotriazole (ABT) is a non-specific cytochrome P450 (CYP) inhibitor.{32434,32435,24115} It does not appear to affect other enzymes, including UDP-glucuronosyltransferases.{32436,20875} ABT acts as a CYP suicide substrate, producing maximal destruction of hepatic and renal microsome CYP protein in vitro at 10 mM.{32436} It is effective in vivo, significantly reducing CYP content in both liver and kidney in rats within two hours.{32436} The effects of ABT on CYP activity is time-dependent, with significant shift in IC50 values with preincubation.{24115}
Brand:CaymanSKU:- 1-aminobenzotriazole (ABT) is a non-specific cytochrome P450 (CYP) inhibitor.{32434,32435,24115} It does not appear to affect other enzymes, including UDP-glucuronosyltransferases.{32436,20875} ABT acts as a CYP suicide substrate, producing maximal destruction of hepatic and renal microsome CYP protein in vitro at 10 mM.{32436} It is effective in vivo, significantly reducing CYP content in both liver and kidney in rats within two hours.{32436} The effects of ABT on CYP activity is time-dependent, with significant shift in IC50 values with preincubation.{24115}
Brand:CaymanSKU:- 1-aminobenzotriazole (ABT) is a non-specific cytochrome P450 (CYP) inhibitor.{32434,32435,24115} It does not appear to affect other enzymes, including UDP-glucuronosyltransferases.{32436,20875} ABT acts as a CYP suicide substrate, producing maximal destruction of hepatic and renal microsome CYP protein in vitro at 10 mM.{32436} It is effective in vivo, significantly reducing CYP content in both liver and kidney in rats within two hours.{32436} The effects of ABT on CYP activity is time-dependent, with significant shift in IC50 values with preincubation.{24115}
Brand:CaymanSKU:- 1-aminobenzotriazole (ABT) is a non-specific cytochrome P450 (CYP) inhibitor.{32434,32435,24115} It does not appear to affect other enzymes, including UDP-glucuronosyltransferases.{32436,20875} ABT acts as a CYP suicide substrate, producing maximal destruction of hepatic and renal microsome CYP protein in vitro at 10 mM.{32436} It is effective in vivo, significantly reducing CYP content in both liver and kidney in rats within two hours.{32436} The effects of ABT on CYP activity is time-dependent, with significant shift in IC50 values with preincubation.{24115}
Brand:CaymanSKU:-
1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence.{26310} ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on NMDA receptors (EC50 = 0.7-0.9 µM) in the presence of low levels (1 µM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 µM) of glutamate.{26311} This compound has been reported to protect against neuron cell death in in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.{26311}
Brand:CaymanSKU:- 1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence.{26310} ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on NMDA receptors (EC50 = 0.7-0.9 µM) in the presence of low levels (1 µM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 µM) of glutamate.{26311} This compound has been reported to protect against neuron cell death in in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.{26311}
Brand:CaymanSKU:- 1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence.{26310} ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on NMDA receptors (EC50 = 0.7-0.9 µM) in the presence of low levels (1 µM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 µM) of glutamate.{26311} This compound has been reported to protect against neuron cell death in in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.{26311}
Brand:CaymanSKU:- 1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence.{26310} ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on NMDA receptors (EC50 = 0.7-0.9 µM) in the presence of low levels (1 µM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 µM) of glutamate.{26311} This compound has been reported to protect against neuron cell death in in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.{26311}
Brand:CaymanSKU:-
The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands.{4614} 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand.{5306} However, 2-AG is chemically unstable and undergoes rapid isomerization to 1-AG (synonymous with 1(3)-AG) both in vitro and in vivo. 1-AG is a frequent contaminant in synthetic 2-AG preparations, and can markedly reduce their cannabinergic potency. 1-AG is a weak CB1 receptor agonist and may have other pharmacologic properties.
Brand:CaymanSKU:62150 - 1 mgAvailable on backorder
The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands.{4614} 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand.{5306} However, 2-AG is chemically unstable and undergoes rapid isomerization to 1-AG (synonymous with 1(3)-AG) both in vitro and in vivo. 1-AG is a frequent contaminant in synthetic 2-AG preparations, and can markedly reduce their cannabinergic potency. 1-AG is a weak CB1 receptor agonist and may have other pharmacologic properties.
Brand:CaymanSKU:62150 - 10 mgAvailable on backorder
The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands.{4614} 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand.{5306} However, 2-AG is chemically unstable and undergoes rapid isomerization to 1-AG (synonymous with 1(3)-AG) both in vitro and in vivo. 1-AG is a frequent contaminant in synthetic 2-AG preparations, and can markedly reduce their cannabinergic potency. 1-AG is a weak CB1 receptor agonist and may have other pharmacologic properties.
Brand:CaymanSKU:62150 - 25 mgAvailable on backorder
The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands.{4614} 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand.{5306} However, 2-AG is chemically unstable and undergoes rapid isomerization to 1-AG (synonymous with 1(3)-AG) both in vitro and in vivo. 1-AG is a frequent contaminant in synthetic 2-AG preparations, and can markedly reduce their cannabinergic potency. 1-AG is a weak CB1 receptor agonist and may have other pharmacologic properties.
Brand:CaymanSKU:62150 - 5 mgAvailable on backorder
1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol (1-AG; Item No. 62150).{10322} 1-Arachidonoyl lysophosphatidic acid binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM.{43503} It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS.{43504} It also decreases differentiation of HT-29 human colon carcinoma cells to goblet cells in the presence of sodium butyrate.{43505}
Brand:CaymanSKU:10019 - 1 mgAvailable on backorder
1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol (1-AG; Item No. 62150).{10322} 1-Arachidonoyl lysophosphatidic acid binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM.{43503} It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS.{43504} It also decreases differentiation of HT-29 human colon carcinoma cells to goblet cells in the presence of sodium butyrate.{43505}
Brand:CaymanSKU:10019 - 10 mgAvailable on backorder
1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol (1-AG; Item No. 62150).{10322} 1-Arachidonoyl lysophosphatidic acid binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM.{43503} It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS.{43504} It also decreases differentiation of HT-29 human colon carcinoma cells to goblet cells in the presence of sodium butyrate.{43505}
Brand:CaymanSKU:10019 - 5 mgAvailable on backorder
1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol (1-AG; Item No. 62150).{10322} 1-Arachidonoyl lysophosphatidic acid binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM.{43503} It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS.{43504} It also decreases differentiation of HT-29 human colon carcinoma cells to goblet cells in the presence of sodium butyrate.{43505}
Brand:CaymanSKU:10019 - 500 µgAvailable on backorder
1-Arachidoyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906), oleic acid (Item Nos. 90260 | 24659), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in a variety of plant oils, including poppy seed, hazelnut, maize, olive, yellow melon, and date seed oils.{49107,49047}
Brand:CaymanSKU:28556 - 1 mgAvailable on backorder
1-Arachidoyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906), oleic acid (Item Nos. 90260 | 24659), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in a variety of plant oils, including poppy seed, hazelnut, maize, olive, yellow melon, and date seed oils.{49107,49047}
Brand:CaymanSKU:28556 - 10 mgAvailable on backorder
1-Arachidoyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906), oleic acid (Item Nos. 90260 | 24659), and palmitic acid (Item No. 10006627) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in a variety of plant oils, including poppy seed, hazelnut, maize, olive, yellow melon, and date seed oils.{49107,49047}
Brand:CaymanSKU:28556 - 5 mgAvailable on backorder
1-Arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906), palmitic acid (Item No. 10006627), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in butterfat.{46189} Liver levels of 1-arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol are increased in Plin5-overexpressing mice fed a high-fat diet.{53077}
Brand:CaymanSKU:28555 - 1 mgAvailable on backorder
1-Arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906), palmitic acid (Item No. 10006627), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in butterfat.{46189} Liver levels of 1-arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol are increased in Plin5-overexpressing mice fed a high-fat diet.{53077}
Brand:CaymanSKU:28555 - 10 mgAvailable on backorder
1-Arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906), palmitic acid (Item No. 10006627), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in butterfat.{46189} Liver levels of 1-arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol are increased in Plin5-overexpressing mice fed a high-fat diet.{53077}
Brand:CaymanSKU:28555 - 25 mgAvailable on backorder
1-Arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906), palmitic acid (Item No. 10006627), and oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in butterfat.{46189} Liver levels of 1-arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol are increased in Plin5-overexpressing mice fed a high-fat diet.{53077}
Brand:CaymanSKU:28555 - 5 mgAvailable on backorder
1-Arachidoyl-rac-glycerol is a monoacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906) at the sn-1 position. It has been found in pork muscle.{47753}
Brand:CaymanSKU:26947 - 100 mgAvailable on backorder
1-Arachidoyl-rac-glycerol is a monoacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906) at the sn-1 position. It has been found in pork muscle.{47753}
Brand:CaymanSKU:26947 - 250 mgAvailable on backorder
1-Arachidoyl-rac-glycerol is a monoacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906) at the sn-1 position. It has been found in pork muscle.{47753}
Brand:CaymanSKU:26947 - 50 mgAvailable on backorder
1-Arachidoyl-rac-glycerol is a monoacylglycerol that contains arachidic acid (Item Nos. 9000339 | 21906) at the sn-1 position. It has been found in pork muscle.{47753}
Brand:CaymanSKU:26947 - 500 mgAvailable on backorder
1-Azakenpaullone is an analog of kenpaullone (Item No. 10010239) that inhibits glycogen synthase kinase 3β (GSK3β) more potently (IC50 = 18 nM) than CDK1/cyclin B or CDK5/p25 (IC50s = 2.0 and 4.2 µM, respectively).{27328} Through its effects on GSK3β, 1-azakenpaullone stimulates the proliferation of human pancreatic islets and drives the differentiation of mouse embryonic stem cells and Nematostella larvae.{27329,27331,27330}
Brand:CaymanSKU:-Out of stock
1-Azakenpaullone is an analog of kenpaullone (Item No. 10010239) that inhibits glycogen synthase kinase 3β (GSK3β) more potently (IC50 = 18 nM) than CDK1/cyclin B or CDK5/p25 (IC50s = 2.0 and 4.2 µM, respectively).{27328} Through its effects on GSK3β, 1-azakenpaullone stimulates the proliferation of human pancreatic islets and drives the differentiation of mouse embryonic stem cells and Nematostella larvae.{27329,27331,27330}
Brand:CaymanSKU:-Out of stock
1-Azakenpaullone is an analog of kenpaullone (Item No. 10010239) that inhibits glycogen synthase kinase 3β (GSK3β) more potently (IC50 = 18 nM) than CDK1/cyclin B or CDK5/p25 (IC50s = 2.0 and 4.2 µM, respectively).{27328} Through its effects on GSK3β, 1-azakenpaullone stimulates the proliferation of human pancreatic islets and drives the differentiation of mouse embryonic stem cells and Nematostella larvae.{27329,27331,27330}
Brand:CaymanSKU:-Out of stock
1-Benzyl-2-methylpiperazine (hydrochloride) (Item No. 23708) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.
Brand:CaymanSKU:23708 - 1 mgAvailable on backorder
1-Benzyl-2-methylpiperazine (hydrochloride) (Item No. 23708) is an analytical reference standard categorized as a piperazine. This product is intended for research and forensic applications.
Brand:CaymanSKU:23708 - 5 mgAvailable on backorder