Cayman
Showing 15151–15300 of 45550 results
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CHM-1 is an inhibitor of tubulin polymerization (IC50 = 0.68 µM) with anticancer activity.{57149} It inhibits colchicine (Item No. 9000760) tubulin binding by 39% when used at a concentration of 5 µM. CHM-1 inhibits the growth of K562, NCI H226, HCT116, OVCAR-3, RXF 393L, SK-MEL-5, SF-268, and SF-295 cancer cells (mean GI50 = 130 nM). It induces apoptosis in HA22T hepatocellular carcinoma cells in a concentration-dependent manner.{57150} CHM-1 (10 mg/kg) reduces tumor volume and increases survival in an HA22T mouse xenograft model.
Brand:CaymanSKU:27647 - 10 mgAvailable on backorder
CHM-1 is an inhibitor of tubulin polymerization (IC50 = 0.68 µM) with anticancer activity.{57149} It inhibits colchicine (Item No. 9000760) tubulin binding by 39% when used at a concentration of 5 µM. CHM-1 inhibits the growth of K562, NCI H226, HCT116, OVCAR-3, RXF 393L, SK-MEL-5, SF-268, and SF-295 cancer cells (mean GI50 = 130 nM). It induces apoptosis in HA22T hepatocellular carcinoma cells in a concentration-dependent manner.{57150} CHM-1 (10 mg/kg) reduces tumor volume and increases survival in an HA22T mouse xenograft model.
Brand:CaymanSKU:27647 - 5 mgAvailable on backorder
CHM-122 (Item No. 22043) is an analytical reference standard that is structurally categorized as a cannabinoid. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Brand:CaymanSKU:22043 -Out of stock
CHM-122 (Item No. 22043) is an analytical reference standard that is structurally categorized as a cannabinoid. The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications.
Brand:CaymanSKU:22043 -Out of stock
Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group.{44005} It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Cho-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence or absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin (Item No. 21633) and the caveolae-mediated endocytosis inhibitor genistein (Item No. 10005167). It is cytotoxic to H1299 cells (IC50 = 88.5 μg/ml).
Brand:CaymanSKU:25943 - 1 mgAvailable on backorder
Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group.{44005} It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Cho-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence or absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin (Item No. 21633) and the caveolae-mediated endocytosis inhibitor genistein (Item No. 10005167). It is cytotoxic to H1299 cells (IC50 = 88.5 μg/ml).
Brand:CaymanSKU:25943 - 10 mgAvailable on backorder
Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group.{44005} It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assay at charge ratios greater than or equal to 4. Cho-Arg facilitates transfection of plasmid DNA into H1299 and HeLa cells in the presence or absence of fetal bovine serum, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin (Item No. 21633) and the caveolae-mediated endocytosis inhibitor genistein (Item No. 10005167). It is cytotoxic to H1299 cells (IC50 = 88.5 μg/ml).
Brand:CaymanSKU:25943 - 5 mgAvailable on backorder
Cholenic acid is a monohydroxy bile acid.{55080} It is a cholesterol oxidation product formed by 7α-hydroxylation of 27-hydroxycholesterol (Item Nos. 14790 | 14791), as well as a precursor in the biosynthesis of chenodeoxycholic acid (Item No. 10011286). Levels of cholenic acid are increased in patients with neonatal liver disease harboring mutations in CYP7A1, the gene encoding 7α-hydroxylase, as well as in patients with intrahepatic and extrahepatic cholestasis.{55081,55082}
Brand:CaymanSKU:29543 - 1 gAvailable on backorder
Cholenic acid is a monohydroxy bile acid.{55080} It is a cholesterol oxidation product formed by 7α-hydroxylation of 27-hydroxycholesterol (Item Nos. 14790 | 14791), as well as a precursor in the biosynthesis of chenodeoxycholic acid (Item No. 10011286). Levels of cholenic acid are increased in patients with neonatal liver disease harboring mutations in CYP7A1, the gene encoding 7α-hydroxylase, as well as in patients with intrahepatic and extrahepatic cholestasis.{55081,55082}
Brand:CaymanSKU:29543 - 100 mgAvailable on backorder
Cholenic acid is a monohydroxy bile acid.{55080} It is a cholesterol oxidation product formed by 7α-hydroxylation of 27-hydroxycholesterol (Item Nos. 14790 | 14791), as well as a precursor in the biosynthesis of chenodeoxycholic acid (Item No. 10011286). Levels of cholenic acid are increased in patients with neonatal liver disease harboring mutations in CYP7A1, the gene encoding 7α-hydroxylase, as well as in patients with intrahepatic and extrahepatic cholestasis.{55081,55082}
Brand:CaymanSKU:29543 - 250 mgAvailable on backorder
Cholenic acid is a monohydroxy bile acid.{55080} It is a cholesterol oxidation product formed by 7α-hydroxylation of 27-hydroxycholesterol (Item Nos. 14790 | 14791), as well as a precursor in the biosynthesis of chenodeoxycholic acid (Item No. 10011286). Levels of cholenic acid are increased in patients with neonatal liver disease harboring mutations in CYP7A1, the gene encoding 7α-hydroxylase, as well as in patients with intrahepatic and extrahepatic cholestasis.{55081,55082}
Brand:CaymanSKU:29543 - 500 mgAvailable on backorder
Cholestanol is a cholesterol metabolite formed by oxidation and an intermediate in the biosynthesis of chenodeoxycholic acid (Item No. 10011286).{47049} Cholestanol (10 µg/ml) induces apoptosis in cornea and lens epithelial cells and increases the activity of IL-1β converting enzyme (ICE) and CPP32 proteases.{47050} Dietary administration of 1% cholestanol to mice increases serum and liver cholestanol levels and leads to corneal opacities and gallstones and in rats it leads to cholestanol deposition in the cerebellum.{47051} Cholestanol levels are increased in plasma of patients with cerebrotendinous xanthomatosis (CTX), a disease characterized by a deficiency in the mitochondrial enzyme sterol 27-hydrolylase (CYP27A1) that leads to progressive neurological symptoms.{47052}
Brand:CaymanSKU:9003101 - 10 gAvailable on backorder
Cholestanol is a cholesterol metabolite formed by oxidation and an intermediate in the biosynthesis of chenodeoxycholic acid (Item No. 10011286).{47049} Cholestanol (10 µg/ml) induces apoptosis in cornea and lens epithelial cells and increases the activity of IL-1β converting enzyme (ICE) and CPP32 proteases.{47050} Dietary administration of 1% cholestanol to mice increases serum and liver cholestanol levels and leads to corneal opacities and gallstones and in rats it leads to cholestanol deposition in the cerebellum.{47051} Cholestanol levels are increased in plasma of patients with cerebrotendinous xanthomatosis (CTX), a disease characterized by a deficiency in the mitochondrial enzyme sterol 27-hydrolylase (CYP27A1) that leads to progressive neurological symptoms.{47052}
Brand:CaymanSKU:9003101 - 25 gAvailable on backorder
Cholestanol is a cholesterol metabolite formed by oxidation and an intermediate in the biosynthesis of chenodeoxycholic acid (Item No. 10011286).{47049} Cholestanol (10 µg/ml) induces apoptosis in cornea and lens epithelial cells and increases the activity of IL-1β converting enzyme (ICE) and CPP32 proteases.{47050} Dietary administration of 1% cholestanol to mice increases serum and liver cholestanol levels and leads to corneal opacities and gallstones and in rats it leads to cholestanol deposition in the cerebellum.{47051} Cholestanol levels are increased in plasma of patients with cerebrotendinous xanthomatosis (CTX), a disease characterized by a deficiency in the mitochondrial enzyme sterol 27-hydrolylase (CYP27A1) that leads to progressive neurological symptoms.{47052}
Brand:CaymanSKU:9003101 - 5 gAvailable on backorder
Cholestanone is a cholesterol metabolite that has a keto group in place of the 3-hydroxy group on cholesterol.{48122} It decreases TGF-β-induced Smad2 phosphorylation and TGF-β expression and prevents inhibition of DNA synthesis by TGF-β in Mv1Lu cells when used at a concentration of 50 µg/ml.{48123} Increased fecal excretion of cholestenone is correlated with an increased risk of colorectal cancer. Cholestenone reduces serum cholesterol levels in a variety of animal models but is toxic to rats when administered at doses of 700-1,000 mg/kg per day, inducing hypertrophy in and reducing the activity of the adrenal gland.{48124} It has been used as synthetic intermediate in the synthesis of steroids.{48125}
Brand:CaymanSKU:25713 - 10 gAvailable on backorder
Cholestanone is a cholesterol metabolite that has a keto group in place of the 3-hydroxy group on cholesterol.{48122} It decreases TGF-β-induced Smad2 phosphorylation and TGF-β expression and prevents inhibition of DNA synthesis by TGF-β in Mv1Lu cells when used at a concentration of 50 µg/ml.{48123} Increased fecal excretion of cholestenone is correlated with an increased risk of colorectal cancer. Cholestenone reduces serum cholesterol levels in a variety of animal models but is toxic to rats when administered at doses of 700-1,000 mg/kg per day, inducing hypertrophy in and reducing the activity of the adrenal gland.{48124} It has been used as synthetic intermediate in the synthesis of steroids.{48125}
Brand:CaymanSKU:25713 - 5 gAvailable on backorder
Cholesterol is a major sterol produced in mammalian cells that is required for cell viability and proliferation.{39788} It is a component of mammalian cell membranes that interacts with membrane phospholipids, sphingolipids, and proteins to influence their behavior. Cholesterol is a precursor of steroid hormones, bile acids, and the active form of vitamin D. Impaired cholesterol homeostasis is related to development of various diseases including fatty liver, diabetes, gallstones, dyslipidemia, atherosclerosis, heart attack, and stroke.{39789}
Brand:CaymanSKU:9003100 - 100 gAvailable on backorder
Cholesterol is a major sterol produced in mammalian cells that is required for cell viability and proliferation.{39788} It is a component of mammalian cell membranes that interacts with membrane phospholipids, sphingolipids, and proteins to influence their behavior. Cholesterol is a precursor of steroid hormones, bile acids, and the active form of vitamin D. Impaired cholesterol homeostasis is related to development of various diseases including fatty liver, diabetes, gallstones, dyslipidemia, atherosclerosis, heart attack, and stroke.{39789}
Brand:CaymanSKU:9003100 - 250 gAvailable on backorder
Cholesterol is a major sterol produced in mammalian cells that is required for cell viability and proliferation.{39788} It is a component of mammalian cell membranes that interacts with membrane phospholipids, sphingolipids, and proteins to influence their behavior. Cholesterol is a precursor of steroid hormones, bile acids, and the active form of vitamin D. Impaired cholesterol homeostasis is related to development of various diseases including fatty liver, diabetes, gallstones, dyslipidemia, atherosclerosis, heart attack, and stroke.{39789}
Brand:CaymanSKU:9003100 - 500 gAvailable on backorder
Brand:CaymanSKU:10008052 - 1 eaAvailable on backorder
Brand:CaymanSKU:10008052 - 5 eaAvailable on backorder
Brand:CaymanSKU:10008054 - 1 eaAvailable on backorder
Brand:CaymanSKU:10008057 - 1 eaAvailable on backorder
Brand:CaymanSKU:10008057 - 5 eaAvailable on backorder
Brand:CaymanSKU:10008055 - 1 eaAvailable on backorder
Brand:CaymanSKU:10008055 - 5 eaAvailable on backorder
Brand:CaymanSKU:10008056 - 1 eaAvailable on backorder
Brand:CaymanSKU:10008056 - 5 eaAvailable on backorder
Brand:CaymanSKU:10008053 - 1 eaAvailable on backorder
Brand:CaymanSKU:10008053 - 5 eaAvailable on backorder
The mechanism for the movement of cholesterol from intracellular sites to their ultimate cellular destination is an unresolved question of fundamental importance to cell biology and medicine. Thus, defining mechanisms of intracellular cholesterol transport and identifying the cellular factors involved are therefore of great interest. Cayman’s Cholesterol Cell-Based Detection Assay Kit includes Filipin III, Fixative, and Wash Buffer in a ready to use format. It provides a simple fluorometric method to study mechanisms and biological factors that regulate cholesterol metabolism or movement within cells. A cholesterol trafficking inhibitor, U-18666A, is included as a positive control.
Brand:CaymanSKU:10009779 - 2 x 96 wellsAvailable on backorder
Brand:CaymanSKU:10009868 - 1 eaAvailable on backorder
Cholesterol, particularly in the form of low density lipoproteins (LDL), is well understood to be associated with increased risk of coronary heart disease. The measurement of cholesterol is one of the most common tests performed in the clinical laboratory setting. However, simple and easy assays for cholesterol in the research lab have not been readily available. Cayman’s Cholesterol Fluorometric Assay provides a simple fluorometric method for the sensitive quantitation of total cholesterol in plasma or serum. In our assay, cholesteryl esters in the sample are first hydrolyzed by cholesterol esterase. All cholesterol, whether previously esterified or existing free in the circulation, is then oxidized by cholesterol oxidase to the corresponding ketone and hydrogen peroxide. ADHP (10-acetyl-3,7-dihydroxyphenoxazine) is utilized as a highly sensitive and stable probe for hydrogen peroxide. Horseradish peroxidase catalyzes the reaction of ADHP with hydrogen peroxide to yield the highly fluorescent product resorufin which can be monitored using excitation wavelengths of 530-540 nm and emission wavelengths of 585-595 nm.
Brand:CaymanSKU:10007640 - 480 wellsAvailable on backorder
Cholesterol, particularly in the form of low density lipoproteins (LDL), is well understood to be associated with increased risk of coronary heart disease. The measurement of cholesterol is one of the most common tests performed in the clinical laboratory setting. However, simple and easy assays for cholesterol in the research lab have not been readily available. Cayman’s Cholesterol Fluorometric Assay provides a simple fluorometric method for the sensitive quantitation of total cholesterol in plasma or serum. In our assay, cholesteryl esters in the sample are first hydrolyzed by cholesterol esterase. All cholesterol, whether previously esterified or existing free in the circulation, is then oxidized by cholesterol oxidase to the corresponding ketone and hydrogen peroxide. ADHP (10-acetyl-3,7-dihydroxyphenoxazine) is utilized as a highly sensitive and stable probe for hydrogen peroxide. Horseradish peroxidase catalyzes the reaction of ADHP with hydrogen peroxide to yield the highly fluorescent product resorufin which can be monitored using excitation wavelengths of 530-540 nm and emission wavelengths of 585-595 nm.
Brand:CaymanSKU:10007640 - 96 wellsAvailable on backorder
Cholesterol sulfate is an endogenous component of cell membranes where it serves as a substrate for steroid synthesis, influences lipid metabolism, stabilizes cell membranes, regulates the activity of functional proteins, and plays a role in keratinocyte differentiation and development of the epidermal barrier.{24230} This synthetic formulation can be used to form nonconventional liposomes in order to study cellular membrane properties.{24229}
Brand:CaymanSKU:-Cholesterol sulfate is an endogenous component of cell membranes where it serves as a substrate for steroid synthesis, influences lipid metabolism, stabilizes cell membranes, regulates the activity of functional proteins, and plays a role in keratinocyte differentiation and development of the epidermal barrier.{24230} This synthetic formulation can be used to form nonconventional liposomes in order to study cellular membrane properties.{24229}
Brand:CaymanSKU:-Cholesterol sulfate is an endogenous component of cell membranes where it serves as a substrate for steroid synthesis, influences lipid metabolism, stabilizes cell membranes, regulates the activity of functional proteins, and plays a role in keratinocyte differentiation and development of the epidermal barrier.{24230} This synthetic formulation can be used to form nonconventional liposomes in order to study cellular membrane properties.{24229}
Brand:CaymanSKU:-Cholesterol sulfate is an endogenous component of cell membranes where it serves as a substrate for steroid synthesis, influences lipid metabolism, stabilizes cell membranes, regulates the activity of functional proteins, and plays a role in keratinocyte differentiation and development of the epidermal barrier.{24230} This synthetic formulation can be used to form nonconventional liposomes in order to study cellular membrane properties.{24229}
Brand:CaymanSKU:-Maintaining body cholesterol homeostasis is critical for normal physiological functions and is achieved by a highly regulated balance of de novo synthesis, dietary cholesterol absorption, biliary clearance, and excretion. However, the mechanisms controlling cholesterol absorption are not well understood. A better understanding of the relationship between cholesterol absorption and synthesis may allow for the development of powerful novel strategies for the prevention and treatment of hypercholesterolemia. Cayman’s Cholesterol Uptake Cell-Based Assay Kit provides a convenient tool for studying cholesterol absorption modulators. The kit employs NBD Cholesterol, a fluorescently tagged cholesterol, as a probe for the detection of cholesterol taken up by cultured cells. U-18666A, a cholesterol intracellular trafficking inhibitor, is included as a positive control.
Brand:CaymanSKU:600440 - 1 eaAvailable on backorder
Cholesterol α-linolenate is a cholesterol ester found in fatty streaks and atherosclerotic plaques isolated from human aorta.{37246}
Brand:CaymanSKU:22596 -Out of stock
Cholesterol α-linolenate is a cholesterol ester found in fatty streaks and atherosclerotic plaques isolated from human aorta.{37246}
Brand:CaymanSKU:22596 -Out of stock
Cholesterol β-D-glucoside is a derivative of cholesterol that contains β-D-glucose (Item No. 16775). It is formed from cholesterol and glucosylceramide by β-glucosidase 1.{47305} It activates heat shock transcription factor 1 (Hsf1) in response to heat shock, which increases the expression of heat shock protein 70 (Hsp70) in TIG-3 human fetal lung fibroblasts when used at a concentration of 10 µM.{47306} Cholesterol β-D-glucoside (100 mg/kg) prevents ulcer formation following cold-restraint stress and increases Hsf1 activity, as well as Hsp70 expression and protein levels in rat gastric mucosa.{47307} [Matreya, LLC. Catalog No. 1940]
Brand:CaymanSKU:26713 - 1 mgAvailable on backorder
Cholesterol β-D-glucoside is a derivative of cholesterol that contains β-D-glucose (Item No. 16775). It is formed from cholesterol and glucosylceramide by β-glucosidase 1.{47305} It activates heat shock transcription factor 1 (Hsf1) in response to heat shock, which increases the expression of heat shock protein 70 (Hsp70) in TIG-3 human fetal lung fibroblasts when used at a concentration of 10 µM.{47306} Cholesterol β-D-glucoside (100 mg/kg) prevents ulcer formation following cold-restraint stress and increases Hsf1 activity, as well as Hsp70 expression and protein levels in rat gastric mucosa.{47307} [Matreya, LLC. Catalog No. 1940]
Brand:CaymanSKU:26713 - 10 mgAvailable on backorder
Cholesterol β-D-glucoside is a derivative of cholesterol that contains β-D-glucose (Item No. 16775). It is formed from cholesterol and glucosylceramide by β-glucosidase 1.{47305} It activates heat shock transcription factor 1 (Hsf1) in response to heat shock, which increases the expression of heat shock protein 70 (Hsp70) in TIG-3 human fetal lung fibroblasts when used at a concentration of 10 µM.{47306} Cholesterol β-D-glucoside (100 mg/kg) prevents ulcer formation following cold-restraint stress and increases Hsf1 activity, as well as Hsp70 expression and protein levels in rat gastric mucosa.{47307} [Matreya, LLC. Catalog No. 1940]
Brand:CaymanSKU:26713 - 5 mgAvailable on backorder
Cholesterol-d6 is intended for use as an internal standard for the quantification of cholesterol by GC- or LC-MS. Cholesterol is a major sterol produced in mammalian cells that is required for cell viability and proliferation.{39788} It is a component of mammalian cell membranes that interacts with membrane phospholipids, sphingolipids, and proteins to influence their behavior. Cholesterol is a precursor of steroid hormones, bile acids, and the active form of vitamin D. Impaired cholesterol homeostasis is related to development of various diseases including fatty liver, diabetes, gallstones, dyslipidemia, atherosclerosis, heart attack, and stroke.{39789}
Brand:CaymanSKU:25546 - 1 mgAvailable on backorder
Cholesterol-d6 is intended for use as an internal standard for the quantification of cholesterol by GC- or LC-MS. Cholesterol is a major sterol produced in mammalian cells that is required for cell viability and proliferation.{39788} It is a component of mammalian cell membranes that interacts with membrane phospholipids, sphingolipids, and proteins to influence their behavior. Cholesterol is a precursor of steroid hormones, bile acids, and the active form of vitamin D. Impaired cholesterol homeostasis is related to development of various diseases including fatty liver, diabetes, gallstones, dyslipidemia, atherosclerosis, heart attack, and stroke.{39789}
Brand:CaymanSKU:25546 - 10 mgAvailable on backorder
Cholesterol-d6 is intended for use as an internal standard for the quantification of cholesterol by GC- or LC-MS. Cholesterol is a major sterol produced in mammalian cells that is required for cell viability and proliferation.{39788} It is a component of mammalian cell membranes that interacts with membrane phospholipids, sphingolipids, and proteins to influence their behavior. Cholesterol is a precursor of steroid hormones, bile acids, and the active form of vitamin D. Impaired cholesterol homeostasis is related to development of various diseases including fatty liver, diabetes, gallstones, dyslipidemia, atherosclerosis, heart attack, and stroke.{39789}
Brand:CaymanSKU:25546 - 5 mgAvailable on backorder
Cholesterol-d7 is intended for use as an internal standard for the quantification of cholesterol by GC- or LC-MS. Cholesterol is a major sterol produced in mammalian cells that is required for cell viability and proliferation.{39788} It is a component of mammalian cell membranes that interacts with membrane phospholipids, sphingolipids, and proteins to influence their behavior. Cholesterol is a precursor of steroid hormones, bile acids, and the active form of vitamin D. Impaired cholesterol homeostasis is related to development of various diseases including fatty liver, diabetes, gallstones, dyslipidemia, atherosclerosis, heart attack, and stroke.{39789}
Brand:CaymanSKU:25265 - 1 mgAvailable on backorder
Cholesterol-d7 is intended for use as an internal standard for the quantification of cholesterol by GC- or LC-MS. Cholesterol is a major sterol produced in mammalian cells that is required for cell viability and proliferation.{39788} It is a component of mammalian cell membranes that interacts with membrane phospholipids, sphingolipids, and proteins to influence their behavior. Cholesterol is a precursor of steroid hormones, bile acids, and the active form of vitamin D. Impaired cholesterol homeostasis is related to development of various diseases including fatty liver, diabetes, gallstones, dyslipidemia, atherosclerosis, heart attack, and stroke.{39789}
Brand:CaymanSKU:25265 - 10 mgAvailable on backorder
Cholesterol-d7 is intended for use as an internal standard for the quantification of cholesterol by GC- or LC-MS. Cholesterol is a major sterol produced in mammalian cells that is required for cell viability and proliferation.{39788} It is a component of mammalian cell membranes that interacts with membrane phospholipids, sphingolipids, and proteins to influence their behavior. Cholesterol is a precursor of steroid hormones, bile acids, and the active form of vitamin D. Impaired cholesterol homeostasis is related to development of various diseases including fatty liver, diabetes, gallstones, dyslipidemia, atherosclerosis, heart attack, and stroke.{39789}
Brand:CaymanSKU:25265 - 5 mgAvailable on backorder
Cholesteryl 11,14-eicosadienoate is a cholesterol ester.{46098} It has been used as a synthetic intermediate in the synthesis of cholesterol methyl esters.
Brand:CaymanSKU:26467 - 100 mgAvailable on backorder
Cholesteryl 11,14-eicosadienoate is a cholesterol ester.{46098} It has been used as a synthetic intermediate in the synthesis of cholesterol methyl esters.
Brand:CaymanSKU:26467 - 250 mgAvailable on backorder
Cholesteryl 11,14-eicosadienoate is a cholesterol ester.{46098} It has been used as a synthetic intermediate in the synthesis of cholesterol methyl esters.
Brand:CaymanSKU:26467 - 50 mgAvailable on backorder
Cholesteryl 11,14-eicosadienoate is a cholesterol ester.{46098} It has been used as a synthetic intermediate in the synthesis of cholesterol methyl esters.
Brand:CaymanSKU:26467 - 500 mgAvailable on backorder
Cholesteryl arachidonate is a cholesterol ester that is found in plasma and the adrenal gland.{42068} It is a component of low-density lipoprotein (LDL) and oxidiation of the arachidonate moiety contributes to macrophage activation and foam cell formation in atherosclerosis.{42069} Cholesteryl arachidonate undergoes hydrolysis to release arachidonic acid during ACTH-stimulated prostaglandin synthesis in rat adrenocortical cells.{42070} Levels of cholesteryl arachidonate are increased in the bronchoalveolar lavage fluid (BALF) in pediatric cystic fibrosis patients compared to healthy controls as well as in placentas of women with chorioamnionitis.{42071,42072}
Brand:CaymanSKU:22595 -Out of stock
Cholesteryl arachidonate is a cholesterol ester that is found in plasma and the adrenal gland.{42068} It is a component of low-density lipoprotein (LDL) and oxidiation of the arachidonate moiety contributes to macrophage activation and foam cell formation in atherosclerosis.{42069} Cholesteryl arachidonate undergoes hydrolysis to release arachidonic acid during ACTH-stimulated prostaglandin synthesis in rat adrenocortical cells.{42070} Levels of cholesteryl arachidonate are increased in the bronchoalveolar lavage fluid (BALF) in pediatric cystic fibrosis patients compared to healthy controls as well as in placentas of women with chorioamnionitis.{42071,42072}
Brand:CaymanSKU:22595 -Out of stock
Cholesteryl arachidonate is a cholesterol ester that is found in plasma and the adrenal gland.{42068} It is a component of low-density lipoprotein (LDL) and oxidiation of the arachidonate moiety contributes to macrophage activation and foam cell formation in atherosclerosis.{42069} Cholesteryl arachidonate undergoes hydrolysis to release arachidonic acid during ACTH-stimulated prostaglandin synthesis in rat adrenocortical cells.{42070} Levels of cholesteryl arachidonate are increased in the bronchoalveolar lavage fluid (BALF) in pediatric cystic fibrosis patients compared to healthy controls as well as in placentas of women with chorioamnionitis.{42071,42072}
Brand:CaymanSKU:22595 -Out of stock
Cholesteryl behenate is a cholesterol ester.{47142} It has been used as an internal standard for the quantification of cholesterol esters in human meibum samples.
Brand:CaymanSKU:26466 - 100 mgAvailable on backorder
Cholesteryl behenate is a cholesterol ester.{47142} It has been used as an internal standard for the quantification of cholesterol esters in human meibum samples.
Brand:CaymanSKU:26466 - 25 mgAvailable on backorder
Cholesteryl behenate is a cholesterol ester.{47142} It has been used as an internal standard for the quantification of cholesterol esters in human meibum samples.
Brand:CaymanSKU:26466 - 250 mgAvailable on backorder
Cholesteryl behenate is a cholesterol ester.{47142} It has been used as an internal standard for the quantification of cholesterol esters in human meibum samples.
Brand:CaymanSKU:26466 - 50 mgAvailable on backorder
Cholesteryl docosapentaenoate is a cholesterol ester. It is elevated in liver, plasma, and skeletal muscle of acyl-CoA binding protein (ACBP) knockout mice compared with homozygous controls.{43233}
Brand:CaymanSKU:22718 -Out of stock
Cholesteryl docosapentaenoate is a cholesterol ester. It is elevated in liver, plasma, and skeletal muscle of acyl-CoA binding protein (ACBP) knockout mice compared with homozygous controls.{43233}
Brand:CaymanSKU:22718 -Out of stock
Cholesteryl docosapentaenoate is a cholesterol ester. It is elevated in liver, plasma, and skeletal muscle of acyl-CoA binding protein (ACBP) knockout mice compared with homozygous controls.{43233}
Brand:CaymanSKU:22718 -Out of stock
Cholesteryl docosapentaenoate is a cholesterol ester. It is elevated in liver, plasma, and skeletal muscle of acyl-CoA binding protein (ACBP) knockout mice compared with homozygous controls.{43233}
Brand:CaymanSKU:22718 -Out of stock
Cholesteryl eicosapentaenoate is a cholesterol ester.{47068} It induces cytotoxicity in human monocyte-macrophages in a concentration-dependent manner at concentrations ranging from 88 to 880 μM. Cholesteryl eicosapentaenoate levels are elevated 1.89-fold in the serum of pediatric patients with extrahepatic biliary atresia and decreased in the serum and plasma of patients with Alzheimer’s disease and abetalipoproteinemia, respectively, compared with healthy individuals.{47069,47070,47071}
Brand:CaymanSKU:22719 -Out of stock
Cholesteryl eicosapentaenoate is a cholesterol ester.{47068} It induces cytotoxicity in human monocyte-macrophages in a concentration-dependent manner at concentrations ranging from 88 to 880 μM. Cholesteryl eicosapentaenoate levels are elevated 1.89-fold in the serum of pediatric patients with extrahepatic biliary atresia and decreased in the serum and plasma of patients with Alzheimer’s disease and abetalipoproteinemia, respectively, compared with healthy individuals.{47069,47070,47071}
Brand:CaymanSKU:22719 -Out of stock
Cholesteryl eicosapentaenoate is a cholesterol ester.{47068} It induces cytotoxicity in human monocyte-macrophages in a concentration-dependent manner at concentrations ranging from 88 to 880 μM. Cholesteryl eicosapentaenoate levels are elevated 1.89-fold in the serum of pediatric patients with extrahepatic biliary atresia and decreased in the serum and plasma of patients with Alzheimer’s disease and abetalipoproteinemia, respectively, compared with healthy individuals.{47069,47070,47071}
Brand:CaymanSKU:22719 -Out of stock
Cholesteryl eicosapentaenoate is a cholesterol ester.{47068} It induces cytotoxicity in human monocyte-macrophages in a concentration-dependent manner at concentrations ranging from 88 to 880 μM. Cholesteryl eicosapentaenoate levels are elevated 1.89-fold in the serum of pediatric patients with extrahepatic biliary atresia and decreased in the serum and plasma of patients with Alzheimer’s disease and abetalipoproteinemia, respectively, compared with healthy individuals.{47069,47070,47071}
Brand:CaymanSKU:22719 -Out of stock
Cholesteryl erucate is a cholesterol ester.{46092} It has been used as a standard for the quantification of cholesterol esters in human meibomian gland secretions.
Brand:CaymanSKU:26468 - 100 mgAvailable on backorder
Cholesteryl erucate is a cholesterol ester.{46092} It has been used as a standard for the quantification of cholesterol esters in human meibomian gland secretions.
Brand:CaymanSKU:26468 - 250 mgAvailable on backorder
Cholesteryl erucate is a cholesterol ester.{46092} It has been used as a standard for the quantification of cholesterol esters in human meibomian gland secretions.
Brand:CaymanSKU:26468 - 50 mgAvailable on backorder
Cholesteryl erucate is a cholesterol ester.{46092} It has been used as a standard for the quantification of cholesterol esters in human meibomian gland secretions.
Brand:CaymanSKU:26468 - 500 mgAvailable on backorder
Cholesteryl hemisuccinate is a cholesterol ester with anticancer activity.{36854} It inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells when used at concentrations of 50 and 150 μM, respectively.{36854} Cholesteryl hemisuccinate acts as an ionizable anionic detergent and is commonly used to stabilize unilamellar vesicles and liposomes.{36855} It has also been used as an emulsifying agent in various vesicular drug delivery systems for anticancer drugs, antibiotics, and oligonucleotides and to solubilize various proteins including chemokine receptor 1 as well as erythrocyte ghosts.{24443,36856,36857}
Brand:CaymanSKU:25698 - 1 gAvailable on backorder
Cholesteryl hemisuccinate is a cholesterol ester with anticancer activity.{36854} It inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells when used at concentrations of 50 and 150 μM, respectively.{36854} Cholesteryl hemisuccinate acts as an ionizable anionic detergent and is commonly used to stabilize unilamellar vesicles and liposomes.{36855} It has also been used as an emulsifying agent in various vesicular drug delivery systems for anticancer drugs, antibiotics, and oligonucleotides and to solubilize various proteins including chemokine receptor 1 as well as erythrocyte ghosts.{24443,36856,36857}
Brand:CaymanSKU:25698 - 10 gAvailable on backorder
Cholesteryl hemisuccinate is a cholesterol ester with anticancer activity.{36854} It inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells when used at concentrations of 50 and 150 μM, respectively.{36854} Cholesteryl hemisuccinate acts as an ionizable anionic detergent and is commonly used to stabilize unilamellar vesicles and liposomes.{36855} It has also been used as an emulsifying agent in various vesicular drug delivery systems for anticancer drugs, antibiotics, and oligonucleotides and to solubilize various proteins including chemokine receptor 1 as well as erythrocyte ghosts.{24443,36856,36857}
Brand:CaymanSKU:25698 - 25 gAvailable on backorder
Cholesteryl hemisuccinate is a cholesterol ester with anticancer activity.{36854} It inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells when used at concentrations of 50 and 150 μM, respectively.{36854} Cholesteryl hemisuccinate acts as an ionizable anionic detergent and is commonly used to stabilize unilamellar vesicles and liposomes.{36855} It has also been used as an emulsifying agent in various vesicular drug delivery systems for anticancer drugs, antibiotics, and oligonucleotides and to solubilize various proteins including chemokine receptor 1 as well as erythrocyte ghosts.{24443,36856,36857}
Brand:CaymanSKU:25698 - 5 gAvailable on backorder
Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high concentrations.{34595} As such, it is commonly used as an internal standard for the quantification of cholesterol esters by GC- or LC-mass spectrometry. CEs are major constituents of lipoprotein particles carried in blood and accumulate in the fatty acid lesions of atherosclerotic plaques.{34591,34594} CEs of various fatty acids are major constituents of murine and human adrenal glands.{34592}
Brand:CaymanSKU:21750 -Out of stock
Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high concentrations.{34595} As such, it is commonly used as an internal standard for the quantification of cholesterol esters by GC- or LC-mass spectrometry. CEs are major constituents of lipoprotein particles carried in blood and accumulate in the fatty acid lesions of atherosclerotic plaques.{34591,34594} CEs of various fatty acids are major constituents of murine and human adrenal glands.{34592}
Brand:CaymanSKU:21750 -Out of stock
Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high concentrations.{34595} As such, it is commonly used as an internal standard for the quantification of cholesterol esters by GC- or LC-mass spectrometry. CEs are major constituents of lipoprotein particles carried in blood and accumulate in the fatty acid lesions of atherosclerotic plaques.{34591,34594} CEs of various fatty acids are major constituents of murine and human adrenal glands.{34592}
Brand:CaymanSKU:21750 -Out of stock
Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high concentrations.{34595} As such, it is commonly used as an internal standard for the quantification of cholesterol esters by GC- or LC-mass spectrometry. CEs are major constituents of lipoprotein particles carried in blood and accumulate in the fatty acid lesions of atherosclerotic plaques.{34591,34594} CEs of various fatty acids are major constituents of murine and human adrenal glands.{34592}
Brand:CaymanSKU:21750 -Out of stock