Description
Phospholipase A2 (PLA2) catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids. PLA2 (type V) is a secretory PLA2 (sPLA2) of approximately 14 kDa and is one of the isoforms in the growing list of the PLA2 enzyme family.{3506} This enzyme, rather than the sPLA2 (type II), is responsible for arachidonic acid mobilization leading to prostaglandin production in macrophages and mast cells.{3941,4455,4053,8454} Consistent with this role, sPLA2 (type V) is associated with the golgi apparatus, nuclear envelope, and plasma membrane in murine bone marrow-derived mast cells.{7627} sPLA2 (type V) has been cloned from a variety of species including human, mouse, and rat.{7748,5754,7749} The enzyme is expressed in heart, lung, placenta, and spleen, as well as P388D1 macrophages and mast cells.{3941,4455,7749}
Synonyms: gVPLA2|Secretory Phospholipase A2 (human Group V)
Immunogen: Recombinant human sPLA2 (Type V), W79A mutant
Formulation: 100 µg of protein A-purified antibody
Isotype: IgG1
Applications: ELISA and WB
Origin: Animal/Mouse
Stability: 365 days
Application|ELISA||Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases
