Description
Prostaglandin I synthase (PGIS) catalyzes the isomerization of PGH2 to PGI2. PGI2 (prostacyclin) is a potent vasodilator and inhibitor of platelet aggregation. PGIS is a membrane-bound hemoprotein localized primarily in endothelial cells.{3476} The cloned bovine and human enzymes contain 500 amino acids and a calculated molecular mass of 56,629 and 57,103, respectively.{3477,3478,3475} Northern blot analysis reveals that the mRNA for PGIS is expressed in a wide variety of human tissues and is particularly abundant in ovary, heart, skeletal muscle, lung, and prostate.{3477}
Synonyms: PGIS|Prostacyclin Synthase
Immunogen: Cell surface PGIS from follicular dendritic cell line HK
Formulation: 200 µg of lyophilized protein G-purified monoclonal antibody
Isotype:
Applications: FC, ICC, IHC, IP, and WB
Origin: Animal/Mouse
Stability: 365 days
Application|Flow Cytometry||Application|Immunocytochemistry||Application|Immunohistochemistry||Application|Immunoprecipitation||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cardiovascular System|Heart||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway
