This pan-cytokeratin antibody detects cytokeratin isoforms 4, 5, 6, 8, 10, 13, and 18.{11908} Cytokeratins make up a large family of proteins classified as intermediate filament polypeptides.{11908,15722} They are subdivided into type I (acidic) and type II (basic/neutral) proteins.{15723} Under normal conditions, these proteins are found in epithelial cells as type I/type II pairs.{11908,15740} These pairs provide cellular support as well as contribute to more dynamic processes. Cytokeratins undergo extensive post translational modifications, such as phosphorylation, and are differentially expressed in normal and cancer cells.{15740,15721}
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Host: Mouse, clone C-11 • Species Reactivity: (+) Human • Isotype: IgG1 • Application(s): FC and IF
Synonyms: pan-Cytokeratin
Immunogen:
Formulation: 100 µg of protein A-purified, PE-labeled monoclonal antibody
Isotype: IgG1
Applications: FC and IF
Origin:
Stability: 365 days
Application|Flow Cytometry||Application|Immunofluorescence||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cancer||Research Area|Cell Biology|Cytoskeleton & Motor Proteins
For the quantitation of Human LCN2 concentrations in cell culture supernates, serum, plasma(heparin), saliva and urine.
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For the quantitation of Human CSF3 concentrations in cell culture supernates, serum and plasma (heparin, EDTA, citrate).
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For the quantitation of Mouse Ifng concentrations in bone tissue, cell culture supernates and serum.
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