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Gap-43 (Phospho-Ser41) Polyclonal Antibody – 1 ea

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Cayman
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Gap-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration.{14428} There is also evidence from knockout animals that Gap-43 serves to amplify path finding signals from the growth cone.{14431} Gap-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser41 by protein kinase C (Catalog No. 1609-PKC) modulates the interaction of Gap-43 with actin and may also affect neurotransmitter release during forms of plasticity like LTP.{14429,14430}  

 

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SKU: 10009400 - 1 ea Category:

Description

Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Ser41 of Gap-43 · Host: rabbit · Cross Reactivity: (+) rat Gap-43; expected to react with bovine, canine, chicken, finch, human, mouse, non-human primates, Xenopus, and zebrafish Gap-43 · Application: WB

Synonyms:

Immunogen: phosphopeptide corresponding to amino acid residues surrounding phospho-Ser41 of Gap-43

Formulation: Peptide affinity-purified antibody

Isotype:

Applications: WB

Origin: Animal/Rabbit

Stability: 365 days

Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Neuroscience

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