Immunogen: Synthetic peptide from the an internal region of human 11β-HSD1 • Host: Rabbit • Species reactivity: (+) Human

11β-Hydroxysteroid Dehydrogenase (Type 1) Polyclonal Antibody – 1 ea

Brand:
Cayman
Storage:

11β-Hydroxysteroid dehydrogenase (Type 1) (11β-HSD1) catalyzes the conversion of inactive cortisone to active cortisol in adipose tissue. mRNA and protein for this enzyme have been detected in a wide range of tissues including liver, kidney, testis, lung, heart, and colon.{12000} The enzyme’s expression is developmentally regulated, suggesting its importance in regulation of glucocorticoid action during embryonic development.{11999} Over-expression of 11β-HSD1 results in visceral obesity and metabolic syndrome including insulin-resistant diabetes, hyperlipidemia, and hyperphagia.{9545} Cayman’s 11β-HSD1 Polyclonal Antibody detects a 32 kDa protein in human, mouse, and rat liver samples by western blot analysis. The antibody can be used on paraffin-embedded tissue sections to detect 11β-HSD1 expression.  

 

Available on backorder

Add to quotes
SKU: 10004303 - 1 ea Category:

Description

Immunogen: Synthetic peptide from the an internal region of human 11β-HSD1 • Host: Rabbit • Species reactivity: (+) Human, mouse, and rat • Applications: IHC and WB • 11β-HSD1 catalyzes the conversion of inactive cortisone to active cortisol in adipose tissue. Over-expression of 11β-HSD1 results in visceral obesity and metabolic syndrome including insulin-resistant diabetes, hyperlipidemia, and hyperphagia.

Synonyms: 11-DH|11β-HSD1|Corticosteroid 11β-Dehydrogenase Isozyme 1|Short Chain Dehydrogenase/Reductase Family 26C Member 1

Immunogen: Synthetic peptide from the an internal region of human 11β-HSD1

Formulation: 500 µl of peptide affinity-purified IgG antibody

Isotype:

Applications: IHC and WB

Origin: Animal/Rabbit

Stability: 365 days

Application|Immunohistochemistry||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cardiovascular System|Heart||Research Area|Cardiovascular System|Lipids & Lipoproteins||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Dyslipidemias||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity

Related products