2-Methoxyestradiol (2-ME2) is a natural metabolite of estradiol with potent antitumor and antiangiogenic properties. 2-Methoxyestradiol is a natural metabolite of estradiol with potent antitumor and antiangiogenic properties. Cayman’s 2-Methoxyestradiol ELISA is a competitive assay that can be used for quantification of 2-methoxyestradiol in plasma

2-Methoxyestradiol ELISA Kit – 480 solid wells

Brand:
Cayman
Storage:
-20

2-Methoxyestradiol (2-ME2) is a natural metabolite of estradiol produced by CYP450-dependant hydroxylation followed by catechol-O-methyltransferase-catalyzed O-methylation. Deficiency in catechol-O-methyltransferase is associated with pre-eclampsia. Therefore, 2-ME2 may be utilized as a plasma and urinary diagnostic marker for this disease, as well as a therapeutic supplement for its prevention. Several clinical trials have demonstrated the antitumor effects of 2-ME2 in prostate cancer, breast cancer, renal cell carcinoma, ovarian cancer, glioblastoma, and multiple myeloma. Other studies indicate that 2-ME2 exhibits more potent cardioprotective effects than estradiol. Cayman’s 2-Methoxyestradiol ELISA Kit is a competitive assay that can be used for quantification of 2-ME2 in plasma, urine, and other sample matrices.  

 

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SKU: 582261 - 480 solid wells Category:

Description

2-Methoxyestradiol (2-ME2) is a natural metabolite of estradiol with potent antitumor and antiangiogenic properties. 2-Methoxyestradiol is a natural metabolite of estradiol with potent antitumor and antiangiogenic properties. Cayman’s 2-Methoxyestradiol ELISA is a competitive assay that can be used for quantification of 2-methoxyestradiol in plasma, urine, and other sample matrices.

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Synonyms:  2-Hydroxyestradiol 2-methyl ester|2-ME2 EIA Kit

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Origin: Animal/Mouse|Animal/Bovine|Animal/Eel|Animal/Rabbit

Application|ELISA||Product Type|Assay Kits|ELISA||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins||Research Area|Endocrinology & Metabolism|Reproductive Biology

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