A fatty acid alkyne; a suicide inhibitor of leukotriene B4 20-hydroxylase and renal CYP450 ω-hydroxylase; completely inhibits the bradykinin-dependent transport of sodium chloride in rat TALH cells; has been used as a click-chemistry probe for labeling palmitoylation substrates in vitro; has been used to study the formation of lipid droplets in live THP-1 macrophages and C. elegans

17-Octadecynoic Acid – 5 mg

Brand:
Cayman
CAS:
34450-18-5
Storage:
-20
UN-No:
Non-Hazardous - /

17-Octadecynoic Acid (17-ODYA) is a fatty acid alkyne. It is a suicide inhibitor of leukotriene B4 20-hydroxylase and renal CYP450 ω-hydroxylase.{376,5823} 17-ODYA (10 µM) completely inhibits the bradykinin-dependent transport of sodium chloride in rat TALH cells.{5823} It has been used as a click-chemistry probe for labeling palmitoylation substrates in vitro.{17771} It has also been used to study the formation of lipid droplets in live THP-1 macrophages and C. elegans.{47045}  

 

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SKU: 90270 - 5 mg Category:

Description

A fatty acid alkyne; a suicide inhibitor of leukotriene B4 20-hydroxylase and renal CYP450 ω-hydroxylase; completely inhibits the bradykinin-dependent transport of sodium chloride in rat TALH cells; has been used as a click-chemistry probe for labeling palmitoylation substrates in vitro; has been used to study the formation of lipid droplets in live THP-1 macrophages and C. elegans

Formal name:

Synonyms:  17-ODYA|Alk-16

Molecular weight: 280.5

CAS: 34450-18-5

Purity: ≥98%

Formulation: A crystalline solid

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