5,8,11-Eicosatriynoic Acid – 1 mg

Brand:
Cayman
CAS:
13488-22-7
Storage:
-20
UN-No:
Non-Hazardous - /

5,8,11-ETI is a nonselective inhibitor of lipoxygenases. It inhibits 12-LO in human platelets with an ID50 value of 24 µM.{66} 5,8,11-ETI also inhibits A23187 and L-cysteine induced LTC4 biosynthesis in mouse mastocytoma cells with an ID50 value of 5 µM.{650} At higher concentrations, 5,8,11-ETI also inhibits cyclooxygenases (ID50 = 340 µM).{66}  

 

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SKU: 90200 - 1 mg Category:

Description

5,8,11-ETI is a nonselective inhibitor of lipoxygenases. It inhibits 12-LO in human platelets with an ID50 value of 24 µM.{66} 5,8,11-ETI also inhibits A23187 and L-cysteine induced LTC4 biosynthesis in mouse mastocytoma cells with an ID50 value of 5 µM.{650} At higher concentrations, 5,8,11-ETI also inhibits cyclooxygenases (ID50 = 340 µM).{66}


Formal name: 5,8,11-eicosatriynoic acid

Synonyms:  5,8,11-ETI

Molecular weight: 300.4

CAS: 13488-22-7

Purity: ≥99%

Formulation: A crystalline solid