An aminoalikylindole which acts as a CB mimetic

WIN 54,461 – 5 mg

Brand:
Cayman
CAS:
166599-63-9
Storage:
-20
UN-No:
Non-Hazardous - /

WIN 54,461 is an aminoalikylindole which acts as a cannabinoid (CB) mimetic, displacing WIN 55212-2 from CB receptors on rat cerebellum membranes (IC50 = 515 nM).{16961} As it antagonizes the inhibition of electrically-induced contractions in isolated mouse vas deferens preparations by tetrahydrocannabinol or pravadoline, it may act as a receptor antagonist.{16961} The physiological effects of WIN 54,461 in vivo have not been examined. This product is intended for research and forensic applications.  

 

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SKU: 9001204 - 5 mg Category:

Description

An aminoalikylindole which acts as a CB mimetic, displacing WIN 55,212-2 from CB receptors on rat cerebellum membranes (IC50 = 515 nM); antagonizes the inhibition of electrically-induced contractions in isolated mouse vas deferens preparations by tetrahydrocannabinol or pravadoline; intended for research and forensic applications

Formal name: [6-bromo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](4-methoxyphenyl)-methanone

Synonyms:  6-Bromopravadoline

Molecular weight: 457.4

CAS: 166599-63-9

Purity: ≥98%

Formulation: A crystalline solid

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