Description
A long-chain saturated fatty acid; binds to the DNA binding domain of p53 (Kd = 12 nM) and inhibits the DNA binding activity; inhibits rat DNA polymerase β and human DNA polymerase λ activity at 100 µM; inhibits human DNA topoisomerase I and II relaxation activity at 25 µM; liver levels are reduced in rats fed a high-fat or a high-fat high-cholesterol diet
Formal name:
Synonyms: Behenic Acid|C22:0|DCA|NSC 32364
Molecular weight: 340.6
CAS: 112-85-6
Purity: ≥98%
Formulation: A crystalline solid