Nitrotyrosine is formed by peroxynitrite-mediated nitration of protein tyrosine residues. Its presence on proteins can be used as a marker for peroxynitrite formation in vivo.{5439

Nitrotyrosine – 25 g

Brand:
Cayman
CAS:
621-44-3
Storage:
22
UN-No:
Non-Hazardous - /

Nitrotyrosine is formed by peroxynitrite-mediated nitration of protein tyrosine residues. Its presence on proteins can be used as a marker for peroxynitrite formation in vivo.{5439,1269,4663,5357} Both free and protein-bound nitrotyrosine are commonly found in mammalian tissues and are increased in pathological conditions.{1269,7112,11380} The basal levels of free nitrotyrosine in human plasma is approximately 3 nM as determined by gas chromatography/mass spectrometry.{10970,7925}  

 

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Description

Nitrotyrosine is formed by peroxynitrite-mediated nitration of protein tyrosine residues. Its presence on proteins can be used as a marker for peroxynitrite formation in vivo.{5439,1269,4663,5357} Both free and protein-bound nitrotyrosine are commonly found in mammalian tissues and are increased in pathological conditions.{1269,7112,11380} The basal levels of free nitrotyrosine in human plasma is approximately 3 nM as determined by GC/MS.{10970,7925}

Formal name: 3-nitro-L-tyrosine

Synonyms:  NT

Molecular weight: 226.2

CAS: 621-44-3

Purity: ≥98%

Formulation: A crystalline solid

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